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| 1 | RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings显示文摘在有前列腺癌症的不同赛跑的病人之中有显著不同;然而,位于这差别下面的机制仍然保持不清楚。这里,我们在场 transcriptome 的一处全面风景用 RNA-seq,越过关于基因熔化的前列腺癌症 transcriptomes 的揭示巨大的差异,长 noncoding RNA (长 ncRNA ) ,其他的拼接和体的变化从中国人口 14 主要前列腺癌症和他们的配对的正常对应物介绍。14 个肿瘤(21.4%) 中的三个在中国病人怀有 TMPRSS2 尔格熔化,和这熔化的低流行进一步在一个另外的肿瘤集合(10/54=18.5%) 被证实。尤其是,二新奇基因熔化, CTAGE5-KHDRBS3 (20/54=37%) 和 USP9Y-TTTY15 (19/54=35.2%) ,在我们的耐心的队经常发生了。介绍的进一步系统的 transcriptional 识别了是在肿瘤表示的差别的众多的长 ncRNAs。在长 ncRNA 和基因的表示之间的关联的分析建议长 ncRNAs 可以在 transcriptional 规定以外有功能。这研究在中国人口产出新卓见进前列腺癌症的致病。 | Shancheng Ren Zhiyu Peng Jian-Hua Mao Yongwei Yu Changjun Yin Xin Gao Zilian Cui Jibin Zhang Kang Yi Weidong Xu Chao Chen Fubo Wang Xinwu Guo Ji Lu Jun Yang Min Wei Zhijian Tian Yinghui Guan Liang Tang Chuanliang Xu Linhui Wang Xu Gao Wei Tian Jian Wang Huanming Yang Jun Wang Yinghao Sun | 2012 | Cell Research2012，22，5： | 66 |
| 2 | Assessing the numbers of SNPs needed to establish molecular IDs and characterize the genetic diversityof soybean cultivars derived from Tokachi nagaha显示文摘The development of a core set of SNP molecular markers that could be widely used in soybean genetic research would greatly facilitate research into the genetic diversity of soybean.We conducted an analysis of Tokachi nagaha and 137 of its descendant soybean cultivars using 4044 SNP markers with the goal of determining the appropriate number of single-nucleotide polymorphisms(SNPs)needed to construct unambiguous molecular IDs and characterize genetic diversity based on a genetic distance matrix correlation method.When the number of SNPs was held constant,the number of accession pairs that could be distinguished increased as the polymorphism informative content(PIC)value of the SNPs increased.A core panel of 20 selected SNPs from 11 linkage groups with a mean PIC value of 0.3703 and a range of 0.3640–0.3749 was able to identify almost all of the accession pairs in our study[9445 pairs(99.92%)].The eight accession pairs that could not be identified with this core SNP set all originated from the same province and some of them had the same parental cultivars.The molecular IDs of the 138 accessions were constructed using the core 20 SNPs.It is known that both the number of SNPs and PIC values should be considered when SNPs are selected for use in the analysis of genetic diversity.In this study,when the PIC value was 0.3460,the correlation coefficient between the genetic distance matrices associated with a panel of 200 SNPs and the total population was>0.800,indicating satisfactory correlation.Our high-accuracy,high-resolution core SNP panel for germplasm fingerprinting and our findings about assessing genetic diversity will likely markedly improve the management and utilization efficiency of soybean germplasm resources. | Zhangxiong Liu Jun Li Xuhong Fan Nang Myint Phyu Sin Htwe Shuming Wang Wen Huang Jiyu Yang Lili Xing Lijun Chen Yinghui Li Rongxia Guan Ruzhen Chang Dechun Wang Lijuan Qiu | 2017 | The Crop Journal2017，5，4： | 10 |
| 3 | Development and utilization of a new chemically-induced soybean library with a high mutation density显示文摘Mutagenized populations have provided important materials for introducing variation and identifying gene function in plants. In this study, an ethyl methanesulfonate(EMS)-induced soybean(Glycine max) population,consisting of 21,600 independent M_2 lines, was developed.Over 1,000 M_(4(5))families, with diverse abnormal phenotypes for seed composition, seed shape, plant morphology and maturity that are stably expressed across different environments and generations were identified. Phenotypic analysis of the population led to the identification of a yellow pigmentation mutant, gyl, that displayed significantly decreased chlorophyll(Chl) content and abnormal chloroplast development. Sequence analysis showed that gyl is allelic to Minn Gold, where a different single nucleotide polymorphism variation in the Mg-chelatase subunit gene(ChlI1a) results in golden yellow leaves. A cleaved amplified polymorphic sequence marker was developed and may be applied to marker-assisted selection for the golden yellow phenotype in soybean breeding. We show that the newly developed soybean EMS mutant population has potential for functional genomics research and genetic improvement in soybean. | Zhongfeng Li Lingxue Jiang Yansong Ma Zhongyan Wei Huilong Hong Zhangxiong Liu Jinhui Lei Ying Liu Rongxia Guan Yong Guo Longguo Jin Lijuan Zhang Yinghui Li Yulong Ren Wei He Ming Liu Nang Myint Phyu Sin Htwe Lin Liu Bingfu Guo Jian Song Bing Tan Guifeng Liu Maiquan Li Xianli Zhang Bo Liu Xuehui Shi Sining Han Sunan Hua Fulai Zhou Lili Yu Yanfei Li Shuang Wang Jun Wang Ruzhen Chang Lijuan Qiu | 2017 | Journal of Integrative Plant Biology2017，59，1： | 6 |
| 4 | Molecular characterization of GmNHX2,a Na^+/H^+ antiporter gene homolog from soybean,and its heterologous expression to improve salt tolerance in Arabidopsis显示文摘Na+/H+ antiporters have been well documented to enhance plant salt tolerance by regulating cellular ion homeostasis. Here, a putative Na+/H+ antiporter gene homolog GmNHX2 from soybean was cloned and predicted to encode a protein of 534 amino acids with 10 putative transmembrane domains. GmNHX2 was expressed in all soybean plant tissues but enriched in roots and its expression was induced by NaCl and polyethylene glycol (PEG) treatments. GmNHX2 exhibits greater sequence similarity with LeNHX2 and AtNHX6 than that of AtNHX1 and AtSOS1. Although phylogenetic analysis clustered GmNHX2 with organellar (tonoplast and vesicles) antiporters, the GmNHX2-EGFP (enhanced green fluorescent protein) fusion protein was possibly localized in the plasma membrane or organelle membrane of transgenic plant cells. Furthermore, transgenic Arabidopsis plants expressing GmNHX2 were more tolerant to high NaCl concentrations during germination and seedling stages when compared with wild-type plants. These results suggest that GmNHX2 is a membrane Na+/H+ antiporter and may function to regulate ion homeostasis under salt stress. | ZHOU GuoAn GUAN RongXia LI YingHui CHANG RuZhen QIU LiJuan | 2009 | Chinese Science Bulletin2009，54，19： | 4 |
| 5 | Genetic contribution of foreign germplasm to elite Chinese soybean (Glycine max) cultivars revealed by SSR markers显示文摘Simple sequence repeats (SSR) marker analysis, combined with pedigree analysis, was car- ried out to trace the genetic constitutes of Suinong 14 and Hefeng 25 in assessing the contribution of for- eign germplasm to those elite cultivars. The overall goal is to accumulate information for further effective utilization of foreign germplasm in Chinese soybean breeding programs. SSR clustering results indicated that the genetic base of elite Chinese soybean culti- vars, including Suinong 14 and Hefeng 25, were broadened and enhanced via introduction of Amsoy from the U.S. and Shishengchangye from Japan. The pedigree analysis showed a very high coefficient of parentage between Shishengchangye and Hefeng 25, between Shishengchangye and Suinong 14, and between Amsoy and Suinong 14. The genetic simi- larity between Suinong 14 and Hefeng 25 was 60.58%. Among 20 linkage groups, more genomic regions were transferred from Hefeng 25 to Suinong 14 in linkage group (LG) I, L and C2 than other LGs. Among the unique alleles of foreign parents, five specific loci in Amsoy were transferred to Suinong 14, and three loci from Shishengchangye to Suinong 14. Some SSR loci were proved to be correlated with phenotypes: two loci for seed size introgressed from Shishengchangye to Suinong 14, and one locus forprotein content from Amsoy to Suinong 14. These results indicate that the two foreign parents might have important contributions in the development of Suinong 14 and Hefeng 25. | QIN Jun CHEN Weiyuan GUAN Rongxia JIANG Chengxi LI Yinghui FU Yashu LIU Zhangxiong ZHANG Mengchen CHANG Ruzhen QIU Lijuan | 2006 | Chinese Science Bulletin2006，51，9： | 4 |
| 6 | Improved USLE-K factor prediction:A case study on water erosion areas in China显示文摘Soil erodibility(K-factor)is an essential factor in soil erosion prediction and conservation practises.The major obstacles to any accurate,large-scale soil erodibility estimation are the lack of necessary data on soil characteristics and the misuse of variable K factor calculators.In this study,we assessed the per-formance of available erodibility estimators Universal Soil Loss Equation(USLE),Revised Universal Soil Loss Equation(RUSLE),Erosion Productivity Impact Calculator(EPIC)and the Geometric Mean Diameter based(Dg)model for different geographic regions based on the Chinese soil erodibility database(CSED).Results showed that previous estimators overestimated almost all K-values.Furthermore,only the USLE and Dg approaches could be directly and reliably applicable to black and loess soil regions.Based on the nonlinear best ftting techniques,we improved soil erodibility prediction by combining Dg and soil or ganic matter(SOM).The NSE,R^(2)and RE values were 0.94,0.67 and 9.5%after calibrating the results independently:similar model performance was showed for the validation process.The results obtained via the proposed approach were more accurate that the former K-value predictions.Moreover,those improvements allowed us to effectively establish a regional soil erodibility map(1:250,000 scale)of water erosion areas in China.The mean K-value of Chinese water erosion regions was 0.0321(t ha h).(ha MJ mm)^(-1)with a standard deviation of 0.0107(t ha h).(ha MJ mm)^(-1);K-values present a decreasing trend from North to South in water erosion areas in China.The yield soil erodibility dataset also sa-tisfactorily corresponded to former K-values from diferent scales(local,regional,and national). | Bin Wang Fenli Zheng Yinghui Guan | 2016 | International Soil and Water Conservation Research2016，4，3： | 2 |
| 7 | Study on the nursing of patients with chronic heart fa显示文摘 | Zhang Yinghui Guan Qingling Zhang Na | 2014 | Chinese Minkang medical2014，27，8： | 1 |
| 8 | Effect of coir geotextile and geocell on ephemeral gully erosion in the Mollisol region of Northeast China显示文摘The unique geomorphological features and farming methods in the Mollisol region of Northeast China increase water catchment flow and aggravate the erosion of ephemeral gully(EG).Vegetation suffers from rain erosion and damage during the growth stage,which brings serious problems to the restoration of grass in the early stage.Therefore,effects of coir geotextile and geocell on EG erosion under four confluence intensities were researched in this study.Results of the simulated water discharge erosion test showed that when the confluence strength was less than 30 L/min,geocell and coir geotextile had a good effect on controlling EG erosion,and sediment yield of geocell and coir geotextile was reduced by 25.95%–37.82%and 73.73%–88.96%,respectively.However,when confluence intensity increased to 40 L/min,protective effect of coir geotextile decreased,and sediment yield rate increased sharply by 189.03%.When confluence intensity increased to 50 L/min,the protective effect of coir geotextile was lost.On the other hand,geocell showed that the greater the flow rate,the better the protective effect.In addition,with the increase in confluence intensity,erosion pattern of coir geotextile developed from sheet erosion to intermittent fall and then to completion of main rill,and the protective effect was gradually weakened.In contrast,the protective effect of EG under geocell was gradually enhanced from the continuous rill to the intermittent rill and finally to the intermittent fall.This study shows that coir geotextile and geocell can prevent EG erosion,and the effect of geocell is better than that of coir geotextile on the surface of EG. | QIN Xijin SUN Yiqiu ZHANG Yan GUAN Yinghui WU Hailong WANG Xinyu WANG Guangyu | 2024 | Journal of Arid Land2024，16，4： | 0 |
| 9 | Sediment yield and erosion–deposition distribution characteristics in ephemeral gullies in black soil areas under geocell protection显示文摘Investigating the effect of geocells on the erosion and deposition distribution of ephemeral gullies in the black soil area of Northeast China can provide a scientific basis for the allocation of soil and water conservation measures in ephemeral gullies.In this study,an artificial simulated confluence test and stereoscopic photogrammetry were used to analyze the distribution characteristics of erosion and deposition in ephemeral gullies protected by geocells and the effect of different confluence flows on the erosion process of ephemeral gullies.Results showed that when the confluence flow was larger,the effect of geocell was more evident,and the protection against ephemeral gully erosion was stronger.When the confluence flow rates were 0.6,1.8,2.4,and 3.0 m^(3)/h,ephemeral gully erosion decreased by 37.84%,26.09%,21.40%,and 35.45%.When the confluence flow rates were 2.4 and 3.0 m^(3)/h,the average sediment yield rate of the ephemeral gully was close to 2.14 kg/(m^(2)•min),and the protective effect of ephemeral gully erosion was enhanced.When the flow rate was higher,the surface fracture of the ephemeral gully was more serious.With an increase in confluence flow rate,the ratio of erosion to deposition increased gradually,the erosion area of ephemeral gullies was expanded,and erosion depth changed minimally.In conclusion,geocell measures changed erosion patterns by altering the rill erosion/deposition ratio,converting erosion from rill erosion to sheet erosion. | WANG Xinyu SU Yu SUN Yiqiu ZHANG Yan GUAN Yinghui WANG Zhirong WU Hailong | 2023 | Journal of Arid Land2023，15，2： | 0 |
| 10 | Leap of Li Metal Anodes from Coin Cells to Pouch Cells:Challenges and Progress显示文摘Li metal anodes have attracted tremendous attention in the last decade because of their high theoretical capacities and low electrochemical potentials.However,until now,there has only been limited success in improving the interfacial and structural stabilities and in realizing the highly controllable and large-scale fabrication of this emerging material;these limitations have posed great obstacles to further performing fundamental and applied studies in Li metal anodes.In this review,we focus on summarizing the existing challenges of Li metal anodes based on the leap from coin cells to pouch cells and on outlining typical methods for designing Li metal anodes on demand;we controllably engineer their surface protection layers and structure sizes by encapsulating structured Li metal inside a variety of synthetic protection layers.We aim to provide a comprehensive understanding and serve as a strategic guide for designing and fabricating practicable Li metal anodes for use in pouch batteries.Challenges and opportunities regarding this burgeoning field are critically evaluated at the end of this review. | Qian Wang Tiantian Lu Yuanbin Xiao Jianyang Wu Lixiang Guan Lifeng Hou Huayun Du Huan Wei Xiaoda Liu Chengkai Yang Yinghui Wei Henghui Zhou Yan Yu | 2023 | Electrochemical Energy Reviews2023，6，1： | 0 |
| 11 | Study on Biological Characteristics of Apricot Blooming in Hongfeng and New Century显示文摘In this paper, the pollination and biology of apricot in Hongfeng and New Century were studied. The results are as follows:(1) The est pollination with the red variety is early, new century's best pollinating varieties is camel yellow.(2) The fl owering period of diff erent cultivars was diff erent, and the fl owering period of Hongfeng and other varieties was 3 - 7 days later than that of Baxing water apricot and other varieties, which provided germplasm for further breeding of late flowering varieties.(3) Hongfeng, the new century and other varieties of self-flowering rate of 0 - 3.61% range, is self-incompatible varieties.(4) The pollen germination rate of diff erent cultivars was higher than 50%, which indicated that the pollen was mature and the fertility was strong, and the reason of low percentage of self-pollination was pollen abortion, the main reason was self and so on. | Xinting Guan Yinghui Yuan Xiujuan Liang | 2018 | Trends in Horticulture2018，1，1： | 0 |
| 12 | Metallogenic model of the Shuangjianzishan Ag-Pb-Zn district,Northeast China:Revealed from integrated geophysical investigation显示文摘The Shuangjianzishan deposit in Inner Mongolia is a typical Ag-Pb-Zn deposit of the southern Great Xing’an Range.Proven reserves of Ag,Pb,and Zn in this deposit have reached the scale of super-large deposits,with favorable metallogenic conditions,strong prospecting signs,and high metallogenic potential.This paper reports a study involving integrated geophysical methods,including controlled-source audio-frequency magnetotelluric,gravity,magnetic,and shallow-seismic-reflection methods,to determine the spatial distribution of ore-controlling structures and subsurface intrusive rock for a depth range of<2000 m in the Shuangjianzishan ore district.The objective of this study is to construct a metallogenic model of the ore district and provide a scientific basis for the exploration of similar deposits in the deep and surrounding regions.We used three-dimensional inversion for controlled-source audio-frequency magnetotelluric data based on the limited memory quasi-Newton algorithm,and three-dimensional physical-property inversion for the gravity and magnetic data to obtain information about the subsurface distribution of ore-controlling structures and intrusive rocks.Under seismic reflection results,regional geology,petrophysical properties,and borehole information,the geophysical investigation shows that the Dashizhai group,which contains the main ore-bearing strata in the ore district,is distributed within a depth range of<1239 m,and is thick in the Xinglongshan ore block and the eastern part of the Shuangjianzishan ore block.The mineralization is spatially associated with a fault system characterized by NE-,NW-,and N-trending faults.The magnetic and electrical models identify large,deep bodies of intrusive rock that are inferred to have been involved in mineralization,with local shallow emplacement of some intrusions.Combining the subsurface spatial distributions of ore-bearing strata,ore-controlling faults,and intrusive rock,we propose two different metallogenic models for the Shuangjianzishan ore district,which provide a scientific basis for further prospecting in the deep regions of the ore district and surrounding areas. | Yihao Wu Jiangtao Han Yunhe Liu Guoqing Ma Fuxing Han Yanchen Yang Lijia Liu Lei Guo Ye Guan Yinghui Zhang Zhenyu Guo Qian Mu | 2022 | Geoscience Frontiers2022，13，2： | 0 |
| 13 | Rational Design of Plasmonic Metal Nanostructures for Solar Energy Conversion显示文摘Plasmonic metal nanostructures,possessing unique surface plasmon resonance properties,show excellent capabilities for light trapping and coupling.On this basis,various plasmonic metal nanostructures offer extraordinary opportunities to promote the conversion efficiency of solar energy to electric energy,hydrogen energy or thermal energy,and so on.In this review article,we highlight a number of recent research achievements on the rational design of plasmonic metal nanostructures so as to maximize the utilization of the entire solar spectrum.Compared with single metal nanoparticles,multiplex(such as multicompositions,sizes,or shapes)nanoparticle structures emphasize advantages in broadening the absorption range and improving light-utilization efficiency.This review concludes with discussions regarding challenges in this research field and proposals of prospects for future directions. | Yawen Wang Junchang Zhang Wenkai Liang He Yang Tianfu Guan Bo Zhao Yinghui Sun Lifeng Chi Lin Jiang | 2022 | CCS Chemistry2022，4，4： | 0 |
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