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| 1 | Spatial distribution and pollution assessment of heavy metals in urban soils from southwest China显示文摘To identify the concentrations and sources of heavy metals, and to assess soil environmental quality, 63 soil samples were collected in Yibin City, Sichuan Province, China. Mean concentrations of As, Pb, Zn, and Cu were 10.55, 61.23, 138.88 and 56.35 mg/kg, respectively. As concentrations were comparable to background values, while Pb, Zn, and Cu concentrations were higher than their corresponding background values. Industrial areas exhibited the highest concentrations of As, Pb, Zn, and Cu, while the lowest concentrations occurred in parks. Statistical analysis was performed and two cluster groups of metals were identified with Pb, Zn, and Cu in one group and As in the other. Spatial distribution maps indicated that Pb, Zn, and Cu were mainly controlled by anthropogenic activities, whereas As could be mainly accounted for by soil parent materials. Pollution index values of As, Pb, Zn, and Cu varied in the range of 0.24-1.93, 0.66-7.24, 0.42-4.19, and 0.62-5.25, with mean values of 0.86, 1.98, 1.61, and 1.78, respectively. The integrated pollution index (IPI) values of these metals varied from 0.82 to 3.54, with a mean of 1.6 and more than 90% of soil samples were moderately or highly contaminated with heavy metals. The spatial distribution of IPI showed that newer urban areas displayed relatively lower heavy metal contamination in comparison with older urban areas. | Guanghui Guo Fengchang Wu Fazhi Xie Ruiqing Zhang | 2012 | Journal of Environmental Sciences2012,24,3: | 86 |
| 2 | Distribution characteristics and ecological risk assessment of PAHs in surface waters of China显示文摘The concentrations of PAHs in the surface waters from seven river basins in China were summarized from literature published from 2000-2010. Subsequently, the risks from individual PAHs and ∑PAHs in the surface waters of China were quantified by comparing the overlap between the probability distributions of exposure concentrations with the probability distributions of toxicity data. The results show that the concentrations of 15 PAHs in the surface waters ranged from 3.09 to 38139.00 ng L-1, with a geometric mean of 474.93 ng L-1. The significantly higher concentrations of the 15 PAHs occurred in the surface waters from northern China when compared with those from southern China. The concentrations of the 15 PAHs in Chinese surface waters were higher than those in other waters worldwide. The MOS10 (margin of safety) values were calculated at 90th percentile values of exposure concentrations and 10th percentile values of toxicity data, with 5.75, 0.17, 2.33, 0.30, 0.57, 1.74, 1.05, and 0.11 for Ace, Ant, Flu, BaP, Flua, Nap, Phe, and Pyr, respectively. The probabilities of the individual PAH concentrations exceeding the 10th percentile value of the toxicity data were 6.06%, 2.07%, 9.51%, and 2.07% for Nap, Ace, Phe, and Flu, respectively, suggesting minimal risk to aquatic organisms; however, the probabilities of BaP, Ant, Flua, and Pyr exceeding this value were 19.49%, 25.46%, 15.15%, and 30.50%, respectively, indicating potential risks. Among the individual PAHs, the ecological risk from Pyr was the highest, followed by, in descending order of risk, Ant, Bap, Flua, Phe, Nap, Flu, and Ace. Additionally, the combined ecological risk of ∑PAH8 in Chinese surface waters was significantly higher than any that of individual PAHs alone. The MOS10 values in the river basins were < 1, except for the Haihe River Basin, suggesting a potential combined risk from ∑PAH8 in the other six river basins. The probabilities calculation indicate that low to high ecological risk from ∑PAH8 for all aquatic species was reported in the Liaohe River Basin (65.58%), Huaihe River Basin (57.15%), Songhua River Basin (46.49%), Pearl River Basin (38.41%), Yangtze River Basin (25.98%), Yellow River Basin (15.92%), and Haihe River Basin (5.22%). | GUO GuangHui WU FengChang HE HongPing ZHANG RuiQing LI HuiXian FENG ChengLian | 2012 | Science China Earth Sciences2012,55,6: | 14 |
| 3 | Development of a model to simulate soil heavy metals lateral migration quantity based on SWAT in Huanjiang watershed,China显示文摘Lateral transportation of soil heavy metals in rainfall events could significantly increase the scope of pollution. Therefore, it is necessary to develop a model with high accuracy to simulate the migration quantity of heavy metals. A model for heavy metal migration simulation was developed based on the SWAT(Soil and Water Assessment Tool) model. This model took into consideration the influence of soil p H value, soil particle size, runoff volume, sediment amount,concentration of water-soluble heavy metals dissolved in runoff and insoluble absorbed to the soil particles. This model was reasonable in Huanjiang watershed, Guangxi Zhuang Autonomous Region, south China, covering an area of 273 km^2. The optimal drainage area threshold was determined by analyzing the effects of watershed subdivision on the simulation results to ensure the simulation accuracy. The main conclusions of this paper were:(1) watershed subdivision could affect simulation migration quantity of heavy metals;(2) the quantity of heavy metals transported by sediment accounted for 97%–99% of the total migration quantity in the study watershed. Therefore, sediment played the most important role in heavy metal migration;(3) the optimal drainage area threshold percentage to ensure high simulation accuracy was determined to be 2.01% of the total watershed;(4) with the optimal threshold percentage, this model could simulate the migration quantity of As, Pb and Cd accurately at the total watershed and subwatershed level. The results of this paper were useful for identifying the key regions with heavy metal migration. | Pengwei Qiao Mei Lei Sucai Yang Jun Yang Xiaoyong Zhou Nan Dong Guanghui Guo | 2019 | Journal of Environmental Sciences2019,31,3: | 11 |
| 4 | Toripalimab plus chemotherapy as second-line treatment in previously EGFR-TKI treated patients with EGFR-mutant-advanced NSCLC:a multicenter phase-II trial显示文摘This multicenter phase-II trial aimed to investigate the efficacy,safety,and predictive biomarkers of toripalimab plus chemotherapy as second-line treatment in patients with EGFR-mutant-advanced NSCLC.Patients who failed from first-line EGFR-TKIs and did not harbor T790M mutation were enrolled.Toripalimab plus carboplatin and pemetrexed were administrated every three weeks for up to six cycles,followed by the maintenance of toripalimab and pemetrexed.The primary endpoint was objective-response rate(ORR).Integrated biomarker analysis of PD-L1 expression,tumor mutational burden(TMB),CD8+tumor-infiltrating lymphocyte(TIL)density,whole-exome,and transcriptome sequencing on tumor biopsies were also conducted.Forty patients were enrolled with an overall ORR of 50.0%and disease-control rate(DCR)of 87.5%.The median progression free survival(PFS)and overall survival were 7.0 and 23.5 months,respectively.The most common treatment-related adverse effects were leukopenia,neutropenia,anemia,ALT/AST elevation,and nausea.Biomarker analysis showed that none of PD-L1 expression,TMB level,and CD8+TIL density could serve as a predictive biomarker.Integrated analysis of whole-exome and transcriptome sequencing data revealed that patients with DSPP mutation had a decreased M2 macrophage infiltration and associated with longer PFS than those of wild type.Toripalimab plus chemotherapy showed a promising anti-tumor activity with acceptable safety profiles as the second-line setting in patients with EGFR-mutant NSCLC.DSPP mutation might serve as a potential biomarker for this combination.A phase-III trial to compare toripalimab versus placebo in combination with chemotherapy in this setting is ongoing(NCT03924050). | Tao Jiang Pingyang Wang Jie Zhang Yanqiu Zhao Jianying Zhou Yun Fan Yongqian Shu Xiaoqing Liu Helong Zhang Jianxing He Guanghui Gao Xiaoqian Mu Zhang Bao Yanjun Xu Renhua Guo Hong Wang Lin Deng Ningqiang Ma Yalei Zhang Hui Feng Sheng Yao Jiarui Wu Luonan Chen Caicun Zhou Shengxiang Ren | 2021 | Signal Transduction and Targeted Therapy2021,6,11: | 8 |
| 5 | Familial Parkinson's Disease-Associated L166P Mutant DJ-1 is Cleaved by Mitochondrial Serine Protease Omi/HtrA2显示文摘Parkinson's disease(PD) is the most common neurodegenerative movement disorder. Mutations in the DJ-1, including L166 P, are responsible for recessive earlyonset PD. Many lines of evidence have shown that L166 P is not only a loss-of-function mutant, but also a proapoptotic-like protein that results in mitochondrial dysfunction. L166 P has been reported to be unstable and to mislocalize to mitochondria. However, the mechanisms underlying the instability of L166 P compared to wild-type DJ-1 remain largely unknown. Here, we showed that Omi/Htr A2, a mitochondrial serine protease that has also been linked to the pathogenesis of PD, contributed to L166 P instability. Omi directly interacted with and cleaved L166 P in mitochondria to decrease the L166 P level. However,Omi did not bind and cleave wild-type DJ-1. Moreover,Omi cleaved L166 P at both serine residues 3 and 121,while L166 P-induced cell death under H_2O_2 treatment was alleviated by over-expression of Omi. Our data reveal a bridge between DJ-1 and Omi, two PD-associated geneticfactors, which contributes to our understanding of the pathogenesis of PD. | Kai Fu Yanfei Wang Dongkai Guo Guanghui Wang Haigang Ren | 2017 | Neuroscience Bulletin2017,33,6: | 6 |
| 6 | Large-Scale Renewable Energy Transmission by HVDC: Challenges and Proposals显示文摘Renewable energy transmission by high-voltage direct current(HVDC)has attracted increasing attention for the development and utilization of large-scale renewable energy under the Carbon Peak and Carbon Neutrality Strategy in China.High-penetration power electronic systems(HPPESs)have gradually formed at the sending end of HVDC transmission.The operation of such systems has undergone profound changes compared with traditional power systems dominated by synchronous generators.New stability issues,such as broadband oscillation and transient over-voltage,have emerged,causing tripping accidents in large-scale renewable energy plants.The analysis methods and design principles of traditional power systems are no longer suitable for HPPESs.In this paper,the mechanisms of broadband oscillation and transient over-voltage are revealed,and analytical methods are proposed for HPPESs,including small-signal impedance analysis and electromagnetic transient simulation.Validation of the theoretical research has been accomplished through its application in several practical projects in north,northwest,and northeast region of China.Finally,suggestions for the construction and operation of the future renewable-energy-dominated power system are put forward. | Weisheng Wang Guanghui Li Jianbo Guo | 2022 | Engineering2022,,12: | 3 |
| 7 | A brief review of forensically important flesh flies (Diptera: Sarcophagidae)显示文摘Forensic entomology could provide valuable data for the minimum postmortem interval (PMImin) estimation and other relevant information,such as causes and circumstances of death.Some representatives of flesh flies are one of the dominant necrophagous insects during early stages of decomposition,demonstrating unique biological characteristics compared with other necrophagous flies.Moreover,they lead to global health concerns as carriers of various pathogenic micro-organisms,and dominantly result in the traumatic myiasis.Thus,sarcophagid flies are considered important in decomposition processes for PMImin estimation.However,the utility of sarcophagid flies has been seriously hampered by limited ecological,biological and taxonomic knowledge of them.The aim of this paper is to provide a brief review on the species,distribution and biological habit of forensically important sarcophagid flies.In addition,the relation between traumatic myiasis and flesh flies,molecular identification methods and developmental pattern of flesh flies are summarized. | Lipin Ren Yanjie Shang Wei Chen Fanming Meng Jifeng Cai Guanghui Zhu Lushi Chen Yong Wang Jianqiang Deng Yadong Guo | 2018 | Forensic Sciences Research2018,3,1: | 3 |
| 8 | Glossy15 Plays an Important Role in the Divergence of the Vegetative Transition between Maize and Its Progenitor, Teosinte显示文摘 | Dingyi Xu Xufeng Wang Cheng Huang Guanghui Xu Yameng Liang Qiuyue Chen Chenglong Wang Dan Li Jinge Tian Lishuan Wu Yaoyao Wu Li Guo Xuehan Wang Weihao Wu Weiqiang Zhang Xiaohong Yang Feng Tian | 2017 | Molecular Plant2017,10,12: | 3 |
| 9 | Current status and developing trends of the contents of heavy metals in sewage sludges in China显示文摘在污水污泥决定重金属集中选择适当处理方法是必要的。我们从位于盖住的 48 个城市的 107 市政的污水处理植物进行了污水污泥样品的重金属集中的国家调查由 Xinjiang 的 31 个省和自治区域,以及香港,澳门和台湾在 2006 的生产和构造军团,并且由比较在污水污泥识别了重金属内容的时间的趋势,调查在 19942001 进行了。在 2006,平均集中作为,在污水污泥的 Cd, Cr, Cu, Hg, Ni, Pb,和 Zn 是 20.2, 1.97, 93.1, 218.8, 2.13, 48.7, 72.3,和 1058 mg 湥? | Jun YANG Mei LEI Tongbin CHEN Ding GAO Guodi ZHENG Guanghui GUO Duujong LEE | 2014 | Frontiers of Environmental Science & Engineering2014,8,5: | 3 |
| 10 | 用高压氧治疗高原脱习服症的效果分析显示文摘目的:探讨用高压氧治疗高原脱习服症的临床效果。方法:对近期结束高原防守任务后赴临潼疗养院进行疗养治疗的31例高原官兵的临床资料进行回顾性研究。我们将这31例患者分为高压氧组和康复疗养组,其中,高压氧组有18例患者,康复疗养组有13例患者。我院对康复疗养组的患者进行康复疗养,在此基础上,对高压氧组的患者进行高压氧治疗。我们在患者入院时、进行治疗后的15天及30天记录其临床症状,并对其临床症状的改善情况进行评分,比较两组患者的评分结果。结果:在治疗后15天后,高压氧组患者的高原脱习服症状评分明显低于康复疗养组的患者,二者相比差异有显著性(P<0.05)。结论:在进行康复疗养的基础上用高压氧治疗高原脱习服症可明显地改善患者的症状。但该方法的治疗效果及成熟的治疗方案尚待进一步的研究。 | 哈振德 Xu Li Shi Runze Guo Guanghui Song Wei Wang Junfang Zhang Quan | 2014 | 当代医药论丛2014,12,14: | 3 |
| 11 | A novel minimally invasive percutaneous nephrolithotomy technique: safety and efficacy report显示文摘 | Guanghui Hu Zhuifeng Guo Huan Liu Ming Luo Min Liu Peng Lai Haimin Zhang Jing Yuan Xudong Yao Junhua Zheng Yunfei Xu | 2014 | Scandinavian Journal of Urology2014,,2: | 2 |
| 12 | Electrochemical Aptasensor Based on Prussian Blue-Chitosan-Glutaraldehyde for the Sensitive Determination of Tetracycline显示文摘In this paper, a novel and sensitive electrochemical aptasensor for detecting tetracycline(TET)with prussian blue(PB) as the label-free signal was fabricated. A PB-chitosan-glutaraldehyde(PB-CS-GA)system acting as the signal indicator was developed to improve the sensitivity of the electrochemical aptasensor.Firstly, the PB-CS-GA was fixed onto the glass carbon electrode surface. Then, colloidal gold nanoparticles(Au NPs) were droped onto the electrode to immobilize the anti-TET aptamer for preparation of the aptasensor.The stepwise assembly process of the aptasensor was characterized by cyclic voltammetry(C-V) and scanning electron microscope(SEM). The target TET captured onto the electrode induced the current response of the electrode due to the non-conducting biomoleculars. Under the optimum operating conditions, the response of differential pulse voltammetry(DPV) was used for detecting the concentration of TET. The proposed aptasensor showed a high sensitivity and a wide linear range of 109-~ 105-M and 105-~ 102-M with the correlation coefficients of 0.994 and 0.992, respectively. The detection limit was 3.2×1010-M(RSD 4.12%). Due to its rapidity, sensitivity and low cost, the proposed aptasensor could be used as a pre-scanning method in TET determination for the analysis of livestock products. | Guanghui Shen Yemin Guo Xia Sun Xiangyou Wang | 2014 | Nano-Micro Letters2014,6,2: | 2 |
| 13 | Progress in octahedral spherical hohlraum study显示文摘In this paper,we give a review of our theoretical and experimental progress in octahedral spherical hohlraum study.From our theoretical study,the octahedral spherical hohlraums with 6 Laser Entrance Holes(LEHs)of octahedral symmetry have robust high symmetry during the capsule implosion at hohlraum-to-capsule radius ratio larger than 3.7.In addition,the octahedral spherical hohlraums also have potential superiority on low backscattering without supplementary technology.We studied the laser arrangement and constraints of the octahedral spherical hohlraums,and gave a design on the laser arrangement for ignition octahedral hohlraums.As a result,the injection angle of laser beams of 50°-60°was proposed as the optimum candidate range for the octahedral spherical hohlraums.We proposed a novel octahedral spherical hohlraum with cylindrical LEHs and LEH shields,in order to increase the laser coupling efficiency and improve the capsule symmetry and to mitigate the influence of the wall blowoff on laser transport.We studied on the sensitivity of the octahedral spherical hohlraums to random errors and compared the sensitivity among the octahedral spherical hohlraums,the rugby hohlraums and the cylindrical hohlraums,and the results show that the octahedral spherical hohlraums are robust to these random errors while the cylindrical hohlraums are the most sensitive.Up till to now,we have carried out three experiments on the spherical hohlraum with 2 LEHs on Shenguang(SG)laser facilities,including demonstration of improving laser transport by using the cylindrical LEHs in the spherical hohlraums,spherical hohlraum energetics on the SGIII prototype laser facility,and comparisons of laser plasma instabilities between the spherical hohlraums and the cylindrical hohlraums on the SGIII laser facility. | Ke Lan Jie Liu Zhichao Li Xufei Xie Wenyi Huo Yaohua Chen Guoli Ren Chunyang Zheng Dong Yang Sanwei Li Zhiwen Yang Liang Guo Shu Li Mingyu Zhang Xiaoying Han Chuanlei Zhai Lifei Hou Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Feng Wang Guanghui Yuan Haijun Zhang Bobin Jiang Lizhen Huang Wei Zhang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Xuewei Deng Dongxia Hu Wei Zhou Huaiting Jia Yongkun Ding Wanguo Zheng Xiantu He | 2016 | Matter and Radiation at Extremes2016,1,1: | 2 |
| 14 | Polaron effects on nonlinear optical rectification in asymmetrical Gaussian potential quantum wells with applied electric fields显示文摘 | Jinghe Wu Kangxian Guo Guanghui Liu | 2014 | Physica B: Physics of Condensed Matter2014,,: | 2 |
| 15 | Dynamic simulation of a space gas-cooled reactor power system with a closed Brayton cycle显示文摘Space nuclear reactor power(SNRP)using a gas-cooled reactor(GCR)and a closed Brayton cycle(CBC)is the ideal choice for future high-power space missions.To investigate the safety characteristics and develop the control strategies for gas-cooled SNRP,transient models for GCR,energy conversion unit,pipes,heat exchangers,pump and heat pipe radiator are established and a system analysis code is developed in this paper.Then,analyses of several operation conditions are performed using this code.In full-power steady-state operation,the core hot spot of 1293 K occurs near the upper part of the core.If 0.4$reactivity is introduced into the core,the maximum temperature that the fuel can reach is 2059 K,which is 914 K lower than the fuel melting point.The system finally has the ability to achieve a new steady-state with a higher reactor power.When the GCR is shut down in an emergency,the residual heat of the reactor can be removed through the conduction of the core and radiation heat transfer.The results indicate that the designed GCR is inherently safe owing to its negative reactivity feedback and passive decay heat removal.This paper may provide valuable references for safety design and analysis of the gas-cooled SNRP coupled with CBC. | Chenglong WANG Ran ZHANG Kailun GUO Dalin ZHANG Wenxi TIAN Suizheng QIU Guanghui SU | 2021 | Frontiers in Energy2021,15,4: | 2 |
| 16 | Effect of high magnetic field on the primary dendrite arm spacing and segregation of directionally solidified superalloy DZ417G显示文摘 | Tao Zhang Weili Ren Jianwen Dong Xu Li Zhongming Ren Guanghui Cao Yunbo Zhong Kang Deng Zuosheng Lei Jianting Guo | 2009 | Journal of Alloys and Compounds2009,,1: | 2 |
| 17 | Polyhexamethylene biguanide chemically modified cotton with desirable hemostatic,inflammation-reducing,intrinsic antibacterial property for infected wound healing显示文摘Medical cotton dressing is cheap and widely used in diversified fields,but in the application of promoting wound healing,the continuous research of multifunctional medical cotton dressing is still of great significance.Here,we developed a fresh type of antibacterial cotton dressing through a succinct strategy based on chemically anchoring polyhexamethylene biguanide(PHMB).Intriguingly,after PHMB modification,the cotton dressing exhibited outstanding antibacterial performance which could maintain>99.99%antibacterial rate after several treatments,including washing 50 times,repeated use 10 times,UV irradiation for 7 days,cationic dyes dying,and conditioned under 90℃water bath for 2 h.In addition,the water contact angle of cotton dressing increased dramatically from 0°to 111°,which could facilitate bacterial adhesion,thus further enhance the antibacterial efficiency,and easily remove the bacterial debris.Apart from that,the developed cotton dressing showed good cytocompatibility,promoted blood clotting and expression of platelets,and promoted the wound healing process in the infection intervened skin wound model.Taken together,this antibacterial cotton dressing with desirable blood clotting,sustained protection against bacterial infection and bacterial removal features shows the potential to be a candidate for infected skin wound healing. | Chuan Guo Jie Zhang Xiaojun Feng Zhenggui Du Yuanzhang Jiang Yidong Shi Guanghui Yang Lin Tan | 2022 | Chinese Chemical Letters2022,33,6: | 2 |
| 18 | Impacts of nano-scale pore structure and organic amine assembly in porous silica on the kinetics of CO_(2) adsorptive separation显示文摘Nano structure including pore structure and amine assembly is critical for improving sorption and desorption kinetics for adsorptive CO_(2) separation.The present work delineates(1)the influence of the nano-scale pore structure of amine-functionalized solid sorbents,and(2)effect of changing the assembly of amine molecules on surface of nano-porous SiO_(2) on the rates of adsorption and desorption of CO_(2).50PEI-MSN sorbent with inverted cone-shaped pores was prepared by using mesoporous silica nanospheres(MSN)with inverted cone-shaped pores for the loading of polyethyleneimine(PEI).Co-structure-directing(CSD)method was used to synthesize the sorbent with arranged amine assembly at nano-scale(2N-CSD).By comparison with 50PE卜SBA15 as a benchmark sorbent,both sorbents have improved sorption and desorption kinetics.There are significant effects of nano pore structure and amine assembly on the sorption and desorption kinetics.The inverted cone-shaped pores in MSN allow loading polymeric amines in their narrower ends and leaving larger pore mouths open for the transport of CO_(2);50PEI-MSN shows a maximum sorption rate of 81.4 mg·g^(-1)·min^(-1) with average sorption rate of 25.4mg·g^(-1)·min^(-1) at 80℃ which are 34%and 59%higher than the corresponding values for 50PEI-SBA15;a maximum desorption rate of 38.4mg·g^(-1)·min^(-1) with average desorption rate of 11.8 mg·g^(-1)·min^(-1) ramping from 30 to 95℃ which are 37%and 156%higher than the corresponding values for 50PEI-SBA15.The arranged monolayer-like amine assembly on surface of nanoporous SiO_(2) likely provides high amine sorption sites through improved accessibility of amine,and 2N-CSD shows a maximum sorption rate of 60.5 mg·g^(-1)·min^(-1),with average sorption rate of 12.8mg·g^(-1)·min^(-1) at 300C which are 108%and 205%higher than the corresponding values for 50PEI-SBA15;a lower maximum desorption rate of 9.7 mg g'1min'1 and average desorption rate of 9.8mg·g^(-1)·min^(-1) ramping from 30 to 95℃ which is 250%higher than the corresponding value for 50PEI-SBA15.The present work demonstrates the importance of tailoring nano-scale pore structure and amine assembly for significantly improving sorption and desorption kinetics of adsorptive CO_(2) separation. | Feijian Lou Guanghui Zhang Limin Ren Xinwen Guo Chunshan Song | 2021 | Nano Research2021,14,9: | 2 |
| 19 | Profiles design, optimization and geometric analysis of rotors of a novel continuous kneader reactor显示文摘 | WEI Jing GUO Li ZHANG Guanghui | 2010 | Journal of Reinforced Plastics andComposites2010,29,15: | 1 |
| 20 | Pattern of cerebrovascular atherosclerotic stenosis in older Chinese patients with stroke显示文摘 | Fang Yang Ling Liu Min Li Mingquan Li Qin Yin Ruibing Guo Yun Li Guanghui Chen Renliang Zhang Xinfeng Liu | 2013 | Journal of Clinical Neuroscience2013,,7: | 1 |