|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prevalence of Autism Spectrum Disorder in China:A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years显示文摘This study aimed to obtain the first national estimate of the prevalence of autism spectrum disorder(ASD) in Chinese children.We targeted the population of 6 to 12-year-old children for this prevalence study by multistage convenient cluster sampling.The Modified Chinese Autism Spectrum Rating Scale was used for the screening process.Of the target population of 142,086 children,88.5%(n=125,806) participated in the study.A total of 363 children were confirmed as having ASD.The observed ASD prevalence rate was 0.29%(95% CI:0.26%-0.32%) for the overall population.After adjustment for response rates,the estimated number of ASD cases was867 in the target population sample,thereby achieving an estimated prevalence of 0.70%(95% CI:0.64%-0.74%).The prevalence was significantly higher in boys than in girls(0.95%;95% CI:0.87%-1.02% versus 0.30%;95%CI:0.26%-0.34%;P <0.001).Of the 363 confirmed ASD cases,43.3% were newly diagnosed,and most of those(90.4%) were attending regular schools,and 68.8% of the children with ASD had at least one neuropsychiatric comorbidity.Our findings provide reliable data on the estimated ASD prevalence and comorbidities in Chinese children. | Hao Zhou Xiu Xu Weili Yan Xiaobing Zou Lijie Wu Xuerong Luo Tingyu Li Yi Huang Hongyan Guan Xiang Chen Meng Mao Kun Xia Lan Zhang Erzhen Li Xiaoling Ge Lili Zhang Chunpei Li Xudong Zhang Yuanfeng Zhou Ding Ding Andy Shih Eric Fombonne Yi Zheng Jisheng Han Zhongsheng Sun Yong-hui Jiang Yi Wang LATENT-NHC Study Team | 2020 | Neuroscience Bulletin2020，36，9： | 158 |
| 2 | Modifying the Autism Spectrum Rating Scale(6–18 years)to a Chinese Context:An Exploratory Factor Analysis显示文摘The purpose of this study was to explore the psychometric properties of the Chinese version of the autism spectrum rating scale(ASRS). We recruited 1,625community-based children and 211 autism spectrum disorder(ASD) cases from 4 sites, and the parents of all participants completed the Chinese version of the ASRS. A robust weighted least squares means and variance adjusted estimator was used for exploratory factor analysis. The3-factor structure included 59 items suitable for the current sample. The item reliability for the modi?ed Chinese version of the ASRS(MC-ASRS) was excellent. Moreover,with 60 as the cut-off point, receiver operating characteristic analysis showed that the MC-ASRS had excellent discriminate validity, comparable to that of the unmodi?ed Chinese version(UC-ASRS), with area under the curve values of 0.952(95% CI: 0.936–0.967) and 0.948(95% CI:0.930–0.965), respectively. Meanwhile, the con?rm factor analysis revealed that MC-ASRS had a better construct validity than UC-ASRS based on the above factor solution in another children sample. In conclusion, the MC-ASRS shows better ef?cacy in epidemiological screening for ASD in Chinese children. | Hao Zhou Lili Zhang Xuerong Luo Lijie Wu Xiaobing Zou Kun Xia Yimin Wang Xiu Xu Xiaoling Ge Yong-Hui Jiang Eric Fombonne Weili Yan Yi Wang | 2017 | Neuroscience Bulletin2017，33，2： | 8 |
| 3 | Recombinant vaccine containing an RBD-Fc fusion induced protection against SARS-CoV-2 in nonhuman primates and mice显示文摘The novel coronavirus SARS-CoV-2 has infected more than 104 million individuals and resulted in more than 2.2 million deaths worldwide as of February 7,2021(http://gffzze7c39cdc9e894ca6s0xnkvwfvcw0o60wk.ffgz.tsg.suse.edu.cn).The COVID-19 pandemic highlights the need for safe and effective vaccines against SARS-CoV-2 infection. | Shihui Sun Lei He Zhongpeng Zhao Hongjing Gu Xin Fang Tiecheng Wang Xiaolan Yang Shaolong Chen Yongqiang Deng Jiangfan Li Jian Zhao Liang Li Xinwang Li Peng He Ge Li Hao Li Yuee Zhao Chunrun Gao Xiaoling Lang Xin Wang Guoqiang Fei Yan Li Shusheng Geng Yuwei Gao Wenjin Wei Zhongyu Hu Gencheng Han Yansong Sun | 2021 | Cellular & Molecular Immunology2021，18，4： | 5 |
| 4 | Chinese Norms for the Autism Spectrum Rating Scale显示文摘This study aimed to establish norms for the modi?ed Chinese version of the Autism Spectrum Rating Scale(ASRS). Participants were recruited from Shanghai,Harbin, Guangzhou, and Changsha, China, and their parents and teachers were invited to complete the Chinese Parent version and the Teacher version of the ASRS. In both versions, boys had signi?cantly higher sub-scale scores and total score(T-score) by 1–3 and 4–5 points respectively, than girls(both P \ 0.001). Age had weak correlations with some sub-scores and the T-score(r ranged from-0.1859 to 0.0738), and some reached signi?cance(P \ 0.03). The correlations appeared stronger and were more common in females. The T-score based on Chinese norms ideally correlated with the score based on the United States norms in boys and girls for both versions.Norms for the Chinese version of the ASRS for children aged 6–12 years are proposed and may be helpful for screening individuals with autism spectrum disorders from the general population of children. | Hao Zhou Lili Zhang Xiaobing Zou Xuerong Luo Kun Xia Lijie Wu Yimin Wang Xiu Xu Xiaoling Ge Yong-Hui Jiang Eric Fombonne Weili Yan Yi Wang | 2017 | Neuroscience Bulletin2017，33，2： | 5 |
| 5 | Chemical formation and source apportionment of PM_(2.5) at an urban site at the southern foot of the Taihang mountains显示文摘The region along the Taihang Mountains in the North China Plain(NCP) is characterized by serious fine particle pollution. To clarify the formation mechanism and controlling factors, an observational study was conducted to investigate the physical and chemical properties of the fine particulate matter in Jiaozuo city, China. Mass concentrations of the water-soluble ions(WSIs) in PM_(2.5) and gaseous pollutant precursors were measured on an hourly basis from December 1, 2017, to February 27, 2018. The positive matrix factorization(PMF) method and the FLEXible PARTicle(FLEXPART) model were employed to identify the sources of PM_(2.5). The results showed that the average mass concentration of PM_(2.5) was 111 μg/m^(3) during the observation period. Among the major WSIs, sulfate, nitrate, and ammonium(SNA) constituted 62% of the total PM_(2.5) mass, and NO_(3)^(-) ranked the highest with an average contribution of 24.6%. NH_(4)^(+) was abundant in most cases in Jiaozuo. According to chemical balance analysis, SO_(2)-4, NO_(3)^(-), and Cl^(-) might be present in the form of(NH_4)_(2)SO_4, NH_4NO_3, NH_4Cl, and KCl. The liquid-phase oxidation of SO_(2) and NO_(2) was severe during the haze period. The relative humidity and pH were the key factors influencing SO_(4)^(2-) formation. We found that NO_(3)^(-) mainly stemmed from homogeneous gas-phase reactions in the daytime and originated from the hydrolysis of N_(2)O_5 in the nighttime, which was inconsistent with previous studies. The PMF model identified five sources of PM_(2.5) : secondary origin(37.8%), vehicular emissions(34.7%), biomass burning(11.5%), coal combustion(9.4%), and crustal dust(6.6%). | Xiaoyong Liu Mingshi Wang Xiaole Pan Xiyue Wang Xiaolong Yue Donghui Zhang Zhigang Ma Yu Tian Hang Liu Shandong Lei Yuting Zhang Qi Liao Baozhu Ge Dawei Wang Jie Li Yele Sun Pingqing Fu Zifa Wang Hong He | 2021 | Journal of Environmental Sciences2021，33，5： | 5 |
| 6 | Present advances and perspectives of broadband photo-detectors based on emerging 2D-Xenes beyond graphene显示文摘As an excellent optical device,photodetectors have many important applications,such as communication technology,display technology,scientific measurement,fire monitoring,aerospace and biomedical research,and ifs of great significance in the research of nanotechnology and optoelectronics.Graphene,as the first two-dimensional(2D)single-element nanomaterial,has the advantages of high carrier mobility,high strength,high light transmittance and excellent thermal conductivity,and ifs widely used in various nano-optical devices.The great success of graphene has led scientists to extensive research on other 2D single-element nanomaterials.Recently,a group of novel 2D single-element nanomaterials have attracted a lot of attention from scientists because of its excellent physical,chemical,electronic,mechanical and optical properties.Furthermore,it has opened a new door for the realization of new and efficient photodetectors.The group of 2D single-element nanomaterials are called 2D-Xenes and used to make high-performance photodetectors.Currently,there are few studies on photodetectors based on 2D-Xenes,but some 2D-Xenes have been applied to photodetectors and reported.Some of these have excellent photodetection performance,such as high photoresponsivity(R),broad spectral response range,fast photoresponse speed and high specific detectivity(D).Based on the novel 2D-Xenes,this review explores the types and preparation methods of 2D-Xenes,and the working mechanisms of 2D-Xenes photodetectors.Finally,the challenges and development trends of 2D-Xenes in the future are discussed.The research of 2D-Xenes is of great significance for the development of high-performance photodetectors in the future,and is expected to be widely used in other nanoelectronics and optical devices. | Bing Wang Shipeng Zhong Yanqi Ge Huide Wang Xiaoling Luo Han Zhang | 2020 | Nano Research2020，13，4： | 4 |
| 7 | Impact of clinical research on public health policy of neonatal screening for congenital heart disease in China显示文摘Congenital heart disease(CHD)is one of the most common congenital malformations,with a prevalence of approximately 1%in live births.[1,2]Among them,1/4 to 1/3 are major CHD,including critical CHD(CCHD)and serious CHD,which require surgical or catheter intervention before 1 year of age.[3]Major CHD,if left untreated,may cause serious outcomes,such as heart failure,cardiogenic shock,acidosis,and hypoxic-ischemic brain damage,and is one of the leading causes of infant death and childhood disability.[4]The missed diagnosis rate of CCHD in four nurseries ranges from 13%to 48%in developed countries,[4,5]but in China,is>71%before serious symptoms occur after birth.[6]Therefore,screening for CHD is useful for early detection,diagnosis,and treatment and helps to improve prognosis and reduces the medical,economic,and mental burden to both the family and the society.[5,7] | Miao Yang Youping Tian Pin Jia Xiaojing Ma Xiaoling Ge Xiaojing Hu Quming Zhao Fang Liu Bing Jia Weili Yan Qing Gu Guoying Huang | 2022 | Chinese Medical Journal2022，，11： | 3 |
| 8 | Postzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals显示文摘 | August Y Huang Xiaojing Xu Adam Y Ye Qixi Wu Linlin Yan Boxun Zhao Xiaoxu Yang Yao He Sheng Wang Zheng Zhang Bowen Gu Han-Qing Zhao Meng Wang Hua Gao Ge Gao Zhichao Zhang Xiaoling Yang Xiru Wu Yuehua Zhang Liping Wei | 2014 | Cell Research2014，24，11： | 2 |
| 9 | A model for performance of the centrifugal countercurrent air classifier 显示文摘 | Xiaoyan Wang Xiaoling Ge Xuehua Zhao | 1998 | Powder Technology1998，，98： | 1 |
| 10 | A simple magnetic force-based cell patterning method using soft lithography显示文摘Dear Editor,Cell patterning is gaining more and more attention regarding a wide range of applications including cell biology,tissue engineering,and biosensor technology,to name a few.Magnetic force provides a promising tool to pattern cells because it is of excellent biocompatibility,tunable and re- | LI ShanShan LIU XiangQi CHAU Alicia PENG XiaoLing GUIDO Isabella WANG LiLi GE ZiGang XIONG ChunYang | 2015 | Science China(Life Sciences)2015，58，4： | 1 |
| 11 | Study on horizontal turbine classification 显示文摘 | WANG Xiaoyan GE Xiaoling ZHAO Xuehua | 1999 | Powder Technology1999，，102： | 1 |
| 12 | Transport Patterns and Potential Sources of Atmospheric Pollution during the ⅩⅩⅣ Olympic Winter Games Period显示文摘The attainment of suitable ambient air quality standards is a matter of great concern for successfully hosting the ⅩⅩⅣ Olympic Winter Games(OWG). Transport patterns and potential sources of pollutants in Zhangjiakou(ZJK) were investigated using pollutant monitoring datasets and a dispersion model. The PM_(2.5) concentration during February in ZJK has increased slightly(28%) from 2018 to 2021, mostly owing to the shift of main potential source regions of west-central Inner Mongolia and Mongolian areas(2015–18) to the North China Plain and northern Shanxi Province(NCPS) after 2018.Using CO as an indicator, the relative contributions of the different regions to the receptor site(ZJK) were evaluated based on the source-receptor-relationship method(SRR) and an emission inventory. We found that the relative contribution of pollutants from NCPS increased from 33% to 68% during 2019–21. Central Inner Mongolia(CIM) also has an important impact on ZJK under unfavorable weather conditions. This study demonstrated that the effect of pollution control measures in the NCPS and CIM should be strengthened to ensure that the air quality meets the standard during the ⅩⅩⅣ OWG. | Yuting ZHANG Xiaole PAN Yu TIAN Hang LIU Xueshun CHEN Baozhu GE Zhe WANG Xiao TANG Shandong LEI Weijie YAO Yuanzhe REN Yongli TIAN Jie LI Pingqing FU Jinyuan XIN Yele SUN Junji CAO Zifa WANG | 2022 | Advances in Atmospheric Sciences2022，39，10： | 1 |
| 13 | Study on horizontal turbine classification显示文摘 | WANG Xiaoyan GE Xiaoling ZHAO Xuehua | 1999 | Powder Technology1999，102，： | 1 |
| 14 | Dry slidingfriction and wear properties of B4C particulate-reinforced Al-5083 matrix composites显示文摘 | Feng Tang Xiaoling Wu Shirong Ge | 2008 | Wear2008，264，： | 1 |
| 15 | Study on horizontal turbine classification显示文摘 | WANG Xiaoyan GE Xiaoling ZHAO Xuehua | 1999 | Powder Technology1999，102，2： | 1 |
| 16 | Jet Formation Mechanism of the Gamma-Ray-emitting Narrow-line Seyfert 1 Galaxies显示文摘We use a large sample of gamma-ray narrow-line Seyfert 1 galaxies(γ-NLS1 s) to study the jet formation mechanisms. We find that the jet power of γ-NLS1 s is lower than the maximum jet power of the Blandford–Payne(BP) mechanism. At the same time, we find that there is a significant correlation between jet power and accretion disk luminosity. Moreover, the contribution rates of the accretion to the jet power are larger than that of black hole mass to jet power. These results further suggest that the jet of γ NLS1 s is mainly produced by the BP mechanism. | Yongyun Chen Qiusheng Gu Junhui Fan Xiaoling Yu Dingrong Xiong Nan Ding Xiaotong Guo Xue Ge | 2022 | Research in Astronomy and Astrophysics2022，22，9： | 0 |
| 17 | Refractory black carbon aerosols in rainwater in the summer of 2019 in Beijing:Mass concentration,size distribution and wet scavenging ratio显示文摘Black carbon(BC)aerosols in the atmosphere play a significant role in climate systems due to their strong ability to absorb solar radiation.The lifetime of BC depends on atmospheric transport,aging and consequently on wet scavenging processes(in-cloud and below-cloud scavenging).In this study,sequential rainwater samples in eight rainfall events collected in 2 mm interval were measured by a tandem system including a single particle soot photometer(SP2)and a nebulizer.The results showed that the volume-weighted average(VWA)mass concentrations of refractory black carbon(rBC)in each rainfall event varied,ranging from 10.8 to 78.9μg/L.The highest rBC concentrations in the rainwater samples typically occurred in the first fraction from individual rainfall events.The geometric mean median mass-equivalent diameter(MMD)decreased under precipitation,indicating that rBC with larger sizes was relatively aged and preferentially removed by wet scavenging.A positive correlation(R2=0.73)between the VWA mass concentrations of rBC in rainwater and that in ambient air suggested the important contribution of scavenging process.Additionally,the contributions of in-cloud and below-cloud scavenging were distinguished and accounted for 74%and 26%to wet scavenging,respectively.The scavenging ratio of rBC particles was estimated to be 0.06 on average.This study provides helpful information for better understanding the mechanism of rBC wet scavenging and reducing the uncertainty of numerical simulations of the climate effects of rBC. | Shandong Lei Baozhu Ge Hang Liu Jiannong Quan Danhui Xu Yuting Zhang Weijie Yao Lu Lei Yu Tian Qi Liao Xiaoyong Liu Jie Li Jinyuan Xin Yele Sun Pingqing Fu Junji Cao Zifa Wang Xiaole Pan | 2023 | Journal of Environmental Sciences2023，，10： | 0 |
| 18 | Selenization of cotton products with NaHSe endowing the antibacterial activities显示文摘Selenization reaction with the in situ prepared NaHSe has been successfully developed to occur in aqueous solution.The technique affords a method to upload the bioactive Se element on cotton products in semi-industrial scale.The antibacterial tests revealed that the selenized cotton possessed a potent and prolonged antimicrobial effect against both Gram-positive S.aureus and Gram-negative E.coli bacteria.This work discloses a practical method for preparing the selenium-containing antibacterial materials concisely and directly with industrial application potential. | Mingxuan Liu Xiaoling Zhang Sainan Chu Yanyu Ge Tao Huang Yonghong Liu Lei Yu | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 19 | Operando generated copper‐based catalyst enabling efficient electrosynthesis of 2,5‐bis(hydroxymethyl)furan显示文摘Electrocatalytic upgrading of biomass-derived platform molecules has emerged as a sustainable and environmentally benign route to produce high-value chemicals.The main challenge lies in developing efficient catalysts for the selective activation of designated chemical bonds in the presence of various reducible groups.This work demonstrated a high-efficiency electrochemical conversion of 5-hydroxymethylfurfural(HMF)to 2,5-bis(hydroxymethyl)furan(BHMF),an important industrial synthetic reagent.A highly porous Cu-based catalyst was developed that achieved nearly 100%BHMF selectivity and long-term stability.Through comprehensive operando and ex-situ structural characterizations,an electrochemically generated catalyst with abundant Cu/Cu2O interfaces was identified as a catalytically active phase for HMF conversion.Deuterated BHMF,with the potential to produce deuterated drugs,was also synthesized using D2O as the deuterium source.Density functional theory calculations show that the Cu/Cu2O interface structure exhibits relatively low energy barriers for the hydrogenation of HMF to BHMF.This work provides insights into the origin of electrocatalytic hydrogenation activity and highlights the promising potential of the electrocatalytic synthesis of high-value chemicals. | Zhaolu Zhang Kai Huang Xinyue Qiu Wangxin Ge Xiaoling Yang Yihua Zhu Cheng Lian Honglai Liu Hongliang Jiang Chunzhong Li | 2023 | Fundamental Research2023，3，5： | 0 |
| 20 | Comprehensive overview of microRNA function in rheumatoid arthritis显示文摘MicroRNAs(miRNAs),a class of endogenous single-stranded short noncoding RNAs,have emerged as vital epigenetic regulators of both pathological and physiological processes in animals.They direct fundamental cellular pathways and processes by fine-tuning the expression of multiple genes at the posttranscriptional level.Growing evidence suggests that mi RNAs are implicated in the onset and development of rheumatoid arthritis(RA).RA is a chronic inflammatory disease that mainly affects synovial joints.This common autoimmune disorder is characterized by a complex and multifaceted pathogenesis,and its morbidity,disability and mortality rates remain consistently high.More in-depth insights into the underlying mechanisms of RA are required to address unmet clinical needs and optimize treatment.Herein,we comprehensively review the deregulated mi RNAs and impaired cellular functions in RA to shed light on several aspects of RA pathogenesis,with a focus on excessive inflammation,synovial hyperplasia and progressive joint damage.This review also provides promising targets for innovative therapies of RA.In addition,we discuss the regulatory roles and clinical potential of extracellular mi RNAs in RA,highlighting their prospective applications as diagnostic and predictive biomarkers. | Xiaole Peng Qing Wang Wenming Li Gaoran Ge Jiachen Peng Yaozeng Xu Huilin Yang Jiaxiang Bai Dechun Geng | 2023 | Bone Research2023，11，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员