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| 1 | Evolution of disease phenotype in adult and pediatric onset Crohn's disease in a population-based cohort显示文摘AIM:To investigate the evolution of disease phenotypein adult and pediatric onset Crohn's disease(CD) populations,diagnosed between 1977 and 2008.METHODS:Data of 506 incident CD patients were analyzed(age at diagnosis:28.5 years,interquartile range:22-38 years).Both in-and outpatient records were collected prospectively with a complete clinical follow-up and comprehensively reviewed in the population-based Veszprem province database,which included incident patients diagnosed between January 1,1977 and December 31,2008 in adult and pediatric onset CD populations.Disease phenotype according to the Montreal classification and long-term disease course was analysed according to the age at onset in time-dependent univariate and multivariate analysis.RESULTS:Among this population-based cohort,seventy-four(12.8%) pediatric-onset CD patients were identified(diagnosed ≤ 17 years of age).There was no significant difference in the distribution of disease behavior between pediatric(B1:62%,B2:15%,B3:23%) and adult-onset CD patients(B1:56%,B2:21%,B3:23%) at diagnosis,or during follow-up.Overall,the probability of developing complicated disease behaviour was 49.7% and 61.3% in the pediatric and 55.1% and 62.4% in the adult onset patients after 5-and 10-years of follow-up.Similarly,time to change in disease behaviour from non stricturing,non penetrating(B1) to complicated,stricturing or penetrating(B2/B3) disease was not significantly different between pediatric and adult onset CD in a Kaplan-Meier analysis.Calendar year of diagnosis(P = 0.04),ileal location(P < 0.001),perianal disease(P < 0.001),smoking(P = 0.038) and need for steroids(P < 0.001) were associated with presence of,or progression to,complicated disease behavior at diagnosis and during follow-up.A change in disease location was observed in 8.9% of patients and it was associated with smoking status(P = 0.01),but not with age at diagnosis.CONCLUSION:Long-term evolution of disease behavior was not different in pediatric-and adult-onset CD patients in this population-based cohort but was associated to location,perianal disease and smoking status. | Barbara Dorottya Lovasz Laszlo Lakatos Agnes Horvath Istvan Szita Tunde Pandur Michael Mandel Zsuzsanna Vegh Petra Anna Golovics Gabor Mester Mihaly Balogh Csaba Molnar Erzsebet Komaromi Lajos Sandor Kiss Peter Laszlo Lakatos | 2013 | World Journal of Gastroenterology2013，19，14： | 2 |
| 2 | Determination of the Distribution of Elements as a Function of Particle Size in Aerosol Samples by Sequential Leaching显示文摘 | Jozsef H Lavay Klara Polyak Agnes Molnar | 1998 | Analyst1998，123，： | 1 |
| 3 | Determination of the distribution of elements as a function of particle size in aerosol samples by sequential leaching显示文摘 | Lavay Jozsef H Polyak Klara Molnar Agnes | 1998 | Analyst1998，123，： | 1 |
| 4 | The risk of lymphoma and immunomodulators in patients with inflammatory bowel diseases: Results from a population-based cohort in Eastern Europe显示文摘 | Peter L. Lakatos Barbara D. Lovasz Gyula David Tunde Pandur Zsuzsanna Erdelyi Gabor Mester Mihaly Balogh Istvan Szipocs Csaba Molnar Erzsebet Komaromi Petra A. Golovics Zsuzsanna Vegh Michael Mandel Agnes Horvath Miklos Szathmari Lajos S. Kiss Laszlo Laka | 2012 | Journal of Crohn’s and Colitis2012，，： | 1 |
| 5 | Glossary for the implementation of Health in All Policies (HiAP)显示文摘 | Alix Freiler Carles Muntaner Ketan Shankardass Catherine L Mah Agnes Molnar Emilie Renahy Patricia O’Campo | 2013 | Journal of Epidemiology & Community Health2013，，12： | 1 |
| 6 | Determination of the Distribution of Elements as a Function of Particle Size in Aerosol Samples by Sequential leaching显示文摘 | Jozsef H Lavay Klara Polyak Agnes Molnar | 1998 | Analyst1998，123，： | 1 |
| 7 | Symptoms of Depression in Kidney Transplant Recipients: A Cross-sectional Study显示文摘 | Lilla Szeifert Miklos Zsolt Molnar Csaba Ambrus Agnes Borbala Koczy Agnes Zsofia Kovacs Eszter Panna Vamos Andras Keszei Istvan Mucsi Marta Novak | 2009 | American Journal of Kidney Diseases2009，，1： | 1 |
| 8 | Determination of the Distribution of Elements as a Function of Particle Size in Aerosol Samples by Sequential Leaching显示文摘 | Jozsef H Lavay Klara Polyak Agnes Molnar | 1998 | Analyst1998，123，： | 1 |
| 9 | Significantly elevated Helicobacter pylori density and different genotype distribution in erosions as compared with normal gastric biopsy specimen detected by quantitative real-time PCR显示文摘 | Bela Molnar Dominika Szoke Agnes Ruzsovics Zsolt Tulassay | 2008 | European Journal of Gastroenterology & Hepatology2008，，4： | 1 |
| 10 | Determination of the Distribution of Elements as a Function of Particle Size in Agnes Samples by Sequential leaching显示文摘 | Jozsef H Lavay Klara Polyak Agnes Molnar | 1998 | Analyst1998，123，： | 1 |
| 11 | Pancreatic Autoantibodies and Autoantibodies Against Goblet Cells in Pediatric Patients With Inflammatory Bowel Disease显示文摘 | Marta Kovacs Peter Laszlo Lakatos Maria Papp Silvia Jacobsen Eva Nemes Marianne Polgar Eniko Solyom Piroska Bodi Agnes Horvath Katalin Eszter Muller Kriszta Molnar Doloresz Szabo Aron Cseh Antal Dezsofi Andras Arato Gabor Veres | 2012 | Journal of Pediatric Gastroenterology and Nutrition2012，，4： | 1 |
| 12 | The diagnosis of central vestibular disorders based on the complementary examination of the vestibulospinal reflex显示文摘Objectives:Stance and gait unsteadiness along with vertigo contribute to a central vestibular disorder.For objective analysis ultrasound-computer-craniocorpography(US-COMP-CCG)can be used.Aim of the study was to characterize the unsteadiness in central vestibular disorders and discuss the possible diagnostic usage of US-COMP-CCG.Methods and results:Hundred-and-ninety patients(70 male and 120 female,mean age±SD,58.94±15.27)suffering from central vestibular disorder and 230 healthy control patients(78 male and 152 female,mean age±SD,50.94±15.27)were enrolled.Stance and gait analysis was according to vestibulospinal tests of US-COMPCCG.IBM SPSS V24 software was used for statistical analysis.Mann-Whitney U test and Chi-square test were used,along with sensitivity and specificity categorization.The significance level was p<0.05.According to schematic and statistical analysis instability and postural sway were increased in the vertigo population and statistically significant difference was shown.Upon categorical analysis significant correlation was detected[standing test:longitudinal sway(p<0.00001),lateral sway(p<0.00001),forehead covering area parameters(p=0.0001);stepping test:longitudinal deviation(p=0.05),lateral sway(p=0.011)parameters].Conclusions:Clinicians should consider that postural instability is prominently present in this population and might be of a diagnostic importance. | Stefani Maihoub Andras Molnar Laszl Tamas Agnes Szirmai | 2022 | Journal of Otology2022，17，1： | 0 |
| 13 | A possible objective test to detect benign paroxysmal positional vertigo. The role of the caloric and video-head impulse tests in the diagnosis显示文摘Background:Benign paroxysmal positional vertigo(BPPV)is characterized by vertigo lasting from seconds to minutes,induced by head movements.Objectives:Our study aimed to investigate the clinical significance of the caloric vestibular and video head-impulse tests(vHIT)diagnosing the disorder.Methods:68 patients suffering from posterior canal BPPV(25 male,43 females,mean age±SD,54.5±13.2 years)and 56 patients with a normal functioning vestibular system as control were investigated.Bithermal caloric test and vHIT was performed during the same medical check-up.Canal paresis(CP%),gain(GA)and asymmetry(GA%)parameters were calculated.Results:The Dix-Hallpike manoeuvre was only positive in 4%of this population.The CP%parameter was only pathologic in two patients,and there was no significant difference between control and BPPV patients(p=0.76).The GA value was never under 0.8 in this population,but GA%was abnormal in 63.2%.A significant difference comparing the GA%values to the control group was seen(p=0.034).There was no correlation detected between the CP%and GA%values in BPPV.Regarding the GA%value,61%sensitivity and 76%specificity was seen.Conclusion:The Dix-Hallpike manoeuvre was not often positive in the non-acute phase of BPPV;therefore,objective testing is essential.The caloric test does not have clinical significance in BPPV,but vHIT can be helpful based on the GA%parameter。 | Andras Molnar Stefani Maihoub Laszlo Tamas Agnes Szirmai | 2022 | Journal of Otology2022，17，1： | 0 |
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