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| 1 | A handy review of carpal tunnel syndrome:From anatomy to diagnosis and treatment显示文摘Carpal tunnel syndrome(CTS) is the most commonly diagnosed disabling condition of the upper extremities. It is the most commonly known and prevalent type of peripheral entrapment neuropathy that accounts for about 90% of all entrapment neuropathies. This review aims to provide an outline of CTS by considering anat-omy, pathophysiology, clinical manifestation, diagnostic modalities and management of this common condition, with an emphasis on the diagnostic imaging evaluation. | Mohammad Ghasemi-rad Emad Nosair Andrea Vegh Afshin Mohammadi Adam Akkad Emal Lesha Mohammad Hossein Mohammadi Doaa Sayed Ali Davarian Tooraj Maleki-Miyoab Anwarul Hasan | 2014 | World Journal of Radiology2014，6，6： | 24 |
| 2 | Ankylosing spondylitis: A state of the art factual backbone显示文摘Ankylosing spondylitis(AS) is a chronic inflammatory disease that affects 1% of the general population. As one of the most severe types of spondyloarthropathy, AS affects the spinal vertebrae and sacroiliac joints, causing debilitating pain and loss of mobility. The goal of this review is to provide an overview of AS, from the pathophysiological changes that occur as the disease progresses, to genetic factors that are involved with its onset. Considering the high prevalence in the population, and the debilitating life changes that occur as a result of the disease, a strong emphasis is placed on the diagnostic imaging methods that are used to detect this condition, as well as several treatment methods that could improve the health of individuals diagnosed with AS. | Mohammad Ghasemi-rad Hosam Attaya Emal Lesha Andrea Vegh Tooraj Maleki-Miandoab Emad Nosair Nariman Sepehrvand Ali Davarian Hamid Rajebi Abdolghader Pakniat Seyed Amirhossein Fazeli Afshin Mohammadi | 2015 | World Journal of Radiology2015，7，9： | 13 |
| 3 | Ehealth monitoring in irritable bowel syndrome patients treated with low fermentable oligo-, di-, mono-saccharides and polyols diet显示文摘In the present study we report on changes in irritable bowel syndrome-severity scoring system(IBS-SSS)and irritable bowel syndrome-quality of life(IBS-QoL)in 19 IBS patients,aged 18 to 74 years(F/M:14/5),during 12 wk registering their symptoms on the webapplication(www.ibs.constant-care.dk).During a control period of the first 6-wk patients were asked to register their IBS-SSS and IBS-QoL on the web-application weekly without receiving any intervention.Thereafter,low fermentable oligo-,di-,mono-saccharides and polyols(FODMAP)diet(LFD)was introduced for the next6 wk while continuing the registration.Though a small sample size a significant improvement in disease activity(IBS-SSS)was observed during both the control period,median:278(range:122-377),P=0.02,and subsequently during the LFD period,median:151(range:29-334),P<0.01.The IBS-QoL solely changed significantly during the LFD period,median:67(37-120),P<0.01.The significant reduction in disease activity during the control period shows a positive effect of the web-application on IBS symptoms when presented as a'traffic light'.However adding the diet reduced IBSSSS to<150,inactive to mild symptoms.In the future results from larger scale trials are awaited. | Natalia Pedersen Zsuzsanna Vegh Johan Burisch Lisbeth Jensen Dorit Vedel Ankersen Maria Felding Nynne Nyboe Andersen Pia Munkholm | 2014 | World Journal of Gastroenterology2014，20，21： | 7 |
| 4 | Is early limited surgery associated with a more benign disease course in Crohn's disease?显示文摘AIM:To analyze the difference in disease course and need for surgery in patients with Crohn’s disease(CD).METHODS:Data of 506 patients with incident CD were analyzed(age at diagnosis:31.5±13.8 years).Both hospital and outpatient records were collected prospectively with a complete clinical follow-up and comprehensively reviewed in the population-based Veszprem province database,which includes incident CD patients diagnosed between January 1,1977 and December 31,2008.Follow-up data were collected until December 31,2009.All patients included had at least 1year of follow-up available.Patients with indeterminate colitis at diagnosis were excluded from the analysis.RESULTS:Overall,73 patients(14.4%)required resective surgery within 1 year of diagnosis.Steroid exposure and need for biological therapy were lower in patients with early limited surgery(P<0.001 and P=0.09).In addition,surgery rates during follow-up in patients with and without early surgery differed significantly after matching on propensity scores(P<0.001,HR=0.23).The need for reoperation was also lower in patients with early limited resective surgery(P=0.038,HR=0.42)in a Kaplan-Meier and multivariate Cox regression(P=0.04)analysis.However,this advantage was not observed after matching on propensity scores(PLogrank=0.656,PBreslow=0.498).CONCLUSION:Long-term surgery rates and overall exposure to steroids and biological agents were lower in patients with early limited resective surgery,but reoperation rates did not differ. | Petra Anna Golovics Laszlo Lakatos Attila Nagy Tunde Pandur Istvan Szita Mihaly Balogh Csaba Molnar Erzsebet Komaromi Barbara Dorottya Lovasz Michael Mandel Gabor Veres Lajos S Kiss Zsuzsanna Vegh Peter Laszlo Lakatos | 2013 | World Journal of Gastroenterology2013，19，43： | 3 |
| 5 | Evolution of disease phenotype in adult and pediatric onset Crohn's disease in a population-based cohort显示文摘AIM:To investigate the evolution of disease phenotypein adult and pediatric onset Crohn's disease(CD) populations,diagnosed between 1977 and 2008.METHODS:Data of 506 incident CD patients were analyzed(age at diagnosis:28.5 years,interquartile range:22-38 years).Both in-and outpatient records were collected prospectively with a complete clinical follow-up and comprehensively reviewed in the population-based Veszprem province database,which included incident patients diagnosed between January 1,1977 and December 31,2008 in adult and pediatric onset CD populations.Disease phenotype according to the Montreal classification and long-term disease course was analysed according to the age at onset in time-dependent univariate and multivariate analysis.RESULTS:Among this population-based cohort,seventy-four(12.8%) pediatric-onset CD patients were identified(diagnosed ≤ 17 years of age).There was no significant difference in the distribution of disease behavior between pediatric(B1:62%,B2:15%,B3:23%) and adult-onset CD patients(B1:56%,B2:21%,B3:23%) at diagnosis,or during follow-up.Overall,the probability of developing complicated disease behaviour was 49.7% and 61.3% in the pediatric and 55.1% and 62.4% in the adult onset patients after 5-and 10-years of follow-up.Similarly,time to change in disease behaviour from non stricturing,non penetrating(B1) to complicated,stricturing or penetrating(B2/B3) disease was not significantly different between pediatric and adult onset CD in a Kaplan-Meier analysis.Calendar year of diagnosis(P = 0.04),ileal location(P < 0.001),perianal disease(P < 0.001),smoking(P = 0.038) and need for steroids(P < 0.001) were associated with presence of,or progression to,complicated disease behavior at diagnosis and during follow-up.A change in disease location was observed in 8.9% of patients and it was associated with smoking status(P = 0.01),but not with age at diagnosis.CONCLUSION:Long-term evolution of disease behavior was not different in pediatric-and adult-onset CD patients in this population-based cohort but was associated to location,perianal disease and smoking status. | Barbara Dorottya Lovasz Laszlo Lakatos Agnes Horvath Istvan Szita Tunde Pandur Michael Mandel Zsuzsanna Vegh Petra Anna Golovics Gabor Mester Mihaly Balogh Csaba Molnar Erzsebet Komaromi Lajos Sandor Kiss Peter Laszlo Lakatos | 2013 | World Journal of Gastroenterology2013，19，14： | 2 |
| 6 | Prevalence and predictors of hospitalization in Crohn's disease in a prospective population-based inception cohort from 2000-2012显示文摘AIM: To analyze the prevalence, length and predictors of hospitalization in the biological era in the populationbased inception cohort from Veszprem province.METHODS: Data of 331 incident Crohn's disease(CD) patients diagnosed between January 1, 2000 and December 31, 2010 were analyzed(median age at diagnosis: 28; IQR: 21-40 years). Both in- and outpatient records were collected and comprehensively reviewed.RESULTS: Probabilities of first CD-related hospitalization and re-hospitalization were 32.3%, 45.5%,53.7% and 13.6%, 23.9%, 29.8%, respectively after one, three and five years of follow-up in Kaplan-Meier analysis. First-year hospitalizations were related to diagnostic procedures(37%), surgery or disease activity(27% and 21%). Non-inflammatory disease behavior at diagnosis(HR = 1.32, P = 0.001) and perianal disease(HR = 1.47, P = 0.04) were associated with time to first CD-related hospitalization, while disease behavior change(HR = 2.38, P = 0.002) and need for steroids(HR = 3.14, P = 0.003) were associated with time to first re-hospitalization in multivariate analyses.Early CD-related hospitalization(within the year of diagnosis) was independently associated with need for immunosuppressives(OR = 2.08, P = 0.001) and need for surgeries(OR = 7.25, P < 0.001) during the disease course.CONCLUSION: Hospitalization and re-hospitalization rates are still high in this cohort, especially during the first-year after the diagnosis. Non-inflammatory disease behavior at diagnosis was identified as the pivotal predictive factor of both hospitalization and rehospitalization. | Petra A Golovics Laszlo Lakatos Michael D Mandel Barbara D Lovasz Zsuzsanna Vegh Zsuzsanna Kurti Istvan Szita Lajos S Kiss Tunde Pandur Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，23： | 2 |
| 7 | Local intracoronary infusions of bradykinin profoundly reduce the severity of is- chaemia-induced arrhythmia in anaesthetized dogs 显示文摘 | VEGH A SZEKERES L PARRATF J R | 1991 | Br J Pharmacol1991，104，： | 1 |
| 8 | Maturationdependent expression of C1q binding proteins on the cell surface of human monocyte-derived dendritic cells显示文摘 | Goyarts EC Rozengarten K | 2003 | Int Immunopharmacol2003，3，3： | 1 |
| 9 | Noradrenaline infused locally,reduces arrhythmia severity during coronary artery occlusion in anaes- thetised dogs显示文摘 | Vegh A Parratt JR | 2002 | Cardiovasc Res2002，55，1： | 1 |
| 10 | Chemotaxis of human monocyte-derived dendritic cells to complement component C1q is mediated by the receptors gC1qR and cC1qR显示文摘 | Kew RR Gruber BL | 2006 | Mol Immunol2006，43，14： | 1 |
| 11 | New derivation for the rough-surface reflection coefficient and for the distribution of sea-wave elevations显示文摘 | MILLER A R BROWN R M and VEGH E | 1984 | IEE Proceedings and Microwaves Optics Antennas1984，131，2： | 1 |
| 12 | Isosorbide-2-mononitrate reduces the consequences of myocardial ischaemia,including arrhythmia severity:implications for preconditioning显示文摘 | Gyorgy K Vegh A Rastegar M A | 2000 | Cardiovasc Drugs Ther2000，14，： | 1 |
| 13 | Transient ischaemia inducedby rapid caridac pacing results in myocardial preconditioning 显示文摘 | Vegh A Szekeres L Parratt JR | 1991 | Cardiovasc Res1991，25，12： | 1 |
| 14 | 查看详情显示文摘 | Viktor Vegh Tieng Q M Bpereton I M | | 0，，03： | 1 |
| 15 | The role of homocysteine and methylenetetrahydrofolate reductase,methionine synthase,methionine synthase reductase polymorphisms in the development ot cardiovascular diseases and hypertension显示文摘 | MAROSI K AGOTA A VeGH V | 2012 | Orv Hetil2012，153，12： | 1 |
| 16 | New trends in inflammatory bowel disease epidemiology and disease course in Eastern Europe显示文摘 | Barbara D. Lovasz Petra A. Golovics Zsuzsanna Vegh Peter L. Lakatos | 2012 | Digestive and Liver Disease2012，，： | 1 |
| 17 | 2,3-benzodiazepine-type AMPA receptor antagonists and their neuroprotective effects显示文摘 | Szenasi G Vegh M Szabo G | 2005 | J Neurochemistry2005，52，： | 1 |
| 18 | Matrix metalloproteinases and their inhibitors in gestational trophoblastic disease and normal placenta显示文摘 | Vegh GL Selcuk T Z Fulop V | 1999 | Gynecol Oncol1999，75，： | 1 |
| 19 | Matrix metalloproteinases and their inhibitors in gestationa trophoblastic diseases and normal placenta显示文摘 | Vegh GL Selcuk Tuncer Z Fulop V | 1999 | Gynecol Oncol1999，75，2： | 1 |
| 20 | Deranged expression of the E-cadherin/beta-catenin complex and the epidermal growth factor receptor in the clinical evolution and progression of oral squamous cell carcinomas显示文摘 | Bankfalvi A Krassort M Vegh A | | 0，，08： | 1 |
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