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| 1 | Comparison of thermal and light performance in two typical Chinese solar greenhouses in Beijing显示文摘Solar greenhouses have been used for producing vegetables in northern China during early spring,late autumn or over-winter.To improve the thermal performance of solar greenhouses,a traditional type and a retrofitted design were comparatively evaluated.In the retrofitted design,three adjustments were incorporated:the material and structure of the walls,south-facing roof angle,and structure of the north-facing back-roof.The results indicated that the thermal and light performance of the retrofitted greenhouse was much better than that of the traditional greenhouse.Specifically,the daily mean temperature,minimum air temperature,and soil temperature inside the greenhouses after retrofit ting were increased by 1.3,2.4,and 1.9℃,respectively,meanwhile,the daily total solar radiation and PAR were increased by 28.2%and 9.2%,respectively.The wall temperature and its daily variation range were reduced with increasing depth and height.The characteristic analysis of heat storage and release indicated that higher locations have longer heat storage,and shorter heat release time in vertical direction,as well as a lower ratio of heat release to storage.In horizontal direction,the western wall has the shortest heat storage time but the highest heat release flux density.Altogether,the heat storage time of the wall is 1.5 h less than that of the soil.The heat storage flux density of the wall is 1.5 times of that of the soil,but the heat release flux is only 61%of the soil’s value.The total wall heat storage is half of that of the soil in the greenhouse;the total wall heat release amount is only a quarter of that of the soil.Therefore,the thermal environment of solar greenhouses can be further improved by improving the thermal insulation properties of the wall. | Fan Xu Chao Shang Hongling Li Xuzhang Xue Weituo Sun Hong Chen Yinkun Li Zhenhe Zhang Xinxu Li Wenzhong Guo | 2019 | International Journal of Agricultural and Biological Engineering2019，12，1： | 4 |
| 2 | Effect of minocycline on cerebral ischemia-reperfusion injury显示文摘Minocylcine, a tetracycline derivate, has been shown to cross the blood-brain barrier and enter the central nervous system. In this study, cerebral ischemia-reperfusion injury models were established using the suture method, and minocycline was immediately injected intraperitoneally after cerebral ischemia-reperfusion (22.5 mg/kg, initially 45 mg/kg) at a 12-hour interval. Results showed that after minocycline treatment, the volume of cerebral infarction was significantly reduced, the number of surviving cell in the hippocampal CA1 region increased, the number of apoptotic cells decreased, the expression of caspase-3 and poly(adenosine diphosphate-ribose) polymerase-1 protein was down-regulated, and the escape latency in the water maze test was significantly shortened compared with the ischemia-reperfusion group. Our experimental findings indicate that minocycline can protect against neuronal injury induced by focal ischemia-reperfusion, which may be mediated by the inhibition of caspase-3 and poly(adenosine diphosphate-ribose) polymerase-1 protein expression. | Yuanyin Zheng Lijuan Xu Jinbao Yin Zhichao Zhong Hongling Fan Xi Li Quanzhong Chang | 2013 | Neural Regeneration Research2013，8，10： | 4 |
| 3 | ClC-3 chloride channel in hippocampal neuronal apoptosis显示文摘Over-production of nitric oxide is pathogenic for neuronal apoptosis around the ischemic area following ischemic brain injury.In this study,an apoptotic model in rat hippocampal neurons was established by 0.5 mmol/L 3-morpholinosyndnomine(SIN-1),a nitric oxide donor.The models were then cultured with 0.1 mmol/L of 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid(DIDS;the chloride channel blocker) for 18 hours.Neuronal survival was detected using the 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay,and apoptosis was assayed by Hoechst 33342-labeled neuronal DNA fluorescence staining.Western blot analysis and immunochemiluminescence staining were applied to determine the changes of activated caspase-3 and CIC-3 channel proteins.Real-time PCR was used to detect the mRNA expression of CIC-3.The results showed that SIN-1 reduced the neuronal survival rate,induced neuronal apoptosis,and promoted ClC-3 chloride channel protein and mRNA expression in the apoptotic neurons.DIDS reversed the effect of SIN-1.Our findings indicate that the increased activities of the ClC-3 chloride channel may be involved in hippocampal neuronal apoptosis induced by nitric oxide. | Lijuan Xu Shuling Zhang Hongling Fan Zhichao Zhong Xi Li Xiaoxiao Jin Quanzhong Chang | 2013 | Neural Regeneration Research2013，8，32： | 3 |
| 4 | Effects of minocycline on learning and memory of mice following ischemic-hypoxic cerebral injuries显示文摘An ischemic-hypoxic animal model was established using right common carotid artery occlusions and inhalation of low concentrations of oxygen in mice. At 10 days after the ischemic-hypoxic injuries, saline-treated mice exhibited significantly prolonged escape latencies in water-maze tests and significantly shorter memory latencies and more mistakes in step-down tests. In contrast, mice treated with 5 mg/kg minocycline exhibited significant reversals of each of these effects compared with the saline-treated control mice. Moreover, we found that minocycline can relieve brain water content and morphological changes in mice following ischemic-hypoxic cerebral injuries. Accordingly, our findings indicate that minocycline provides some protections against the deleterious effects of these injuries in mice. | Hongling Fan Yuanyin Zheng Lijuan Xu Zhichao Zhong Shining Cai Shuling Zhang Quanzhong Chang | 2012 | Neural Regeneration Research2012，7，2： | 2 |
| 5 | Chloride channel blocker 4,4-diisothiocyanatostilbene-2,2'-disulfonic acid inhibits nitric oxide-induced apoptosis in cultured rat hippocampal neurons显示文摘Apoptosis in cultured rat hippocampal neurons was induced using the nitric oxide donor 3-morpholinosydnonimine, and cells were treated with the chloride channel blocker, 4,4-diisothiocyanatostilbene-2,2'-disulfonic acid. Results showed that the survival rate of neurons was significantly increased after treatment with 4,4-diisothiocyanatostilbene-2,2'-disulfonic acid, and the rate of apoptosis decreased. In addition, the expression of the apoptosis-related proteins poly(adenosine diphosphate-ribose)polymerase-1 and apoptosis-inducing factor were significantly reduced. Our experimental findings indicate that the chloride channel blocker 4,4- diisothiocyanatostilbene-2,2'-disulfonic acid can antagonize apoptotic cell death of hippocampal neurons by inhibiting the expression of the apoptosis-related proteins poly(adenosine diphosphate-ribose)polymerase-1 and apoptosis-inducing factor. | Jinbao Yin Lijuan Xu Shuling Zhang Yuanyin Zheng Zhichao Zhong Hongling Fan XiLi Quanzhong Chang | 2013 | Neural Regeneration Research2013，8，2： | 2 |
| 6 | Microgravity inhibition of lipopolysaccharide-induced tumor necrosis factor-α expression in macrophage cells显示文摘 | Chongzhen Wang Haiying Luo Linnan Zhu Fan Yang Zhulang Chu Hongling Tian Meifu Feng Yong Zhao Peng Shang | 2014 | Inflammation Research2014，，1： | 1 |
| 7 | Research on Steam Piping Optimal Operation in Large-Scale System 显示文摘 | Hongling Yu Guojun Li Fan Zhu etal | 2007 | Challenges of Power Engineering and Environment2007，，8： | 1 |
| 8 | Structure and second-order NLO property of the molecules bridged through n-vertex bis-substituted carborane (n=5, 6, 7)显示文摘Density functional theory (DFT) B3LYP at 6-31G* level is employed to optimize the structures of the molecules bridged through n-vertex bis-substituted carborane (n=5, 6, 7) and combined with finite field (FF) formalism to calculate the second-order NLO properties. The results indicate that the structures of n-vertex bis-substituted carborane (n=5, 6, 7) are changed due to bridged donor and acceptor moieties. The distances between two C atoms are becoming longer. And the stability and dipole moment are in- fluenced by changing substituted positions of C atoms. The isomers with the substituents connecting with C atoms of lower coordination number have better stability and larger values of polarizability. One-dimensional structure of the molecules bridged through n-vertex bis-substituted carborane (n=5, 6, 7) is in favor of intramolecular charge-transfer. Meanwhile, the isomer with a larger change of dipole moment has larger value of second-order NLO properties during the charge-transfer process. | QIU YongQingt CHEN Hui SUN ShiLing FAN HongLing SU ZhongMin | 2007 | Chinese Science Bulletin2007，52，17： | 0 |
| 9 | Bagging Neural Networks for Predicting Water Consumption显示文摘 | ZHANG Gao FAN Ming ZHAO Hongling | 2005 | 通讯和计算机(中英文版)2005，2，3： | 0 |
| 10 | Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomics显示文摘Dear Editor,Recent study showed that around 80%of coronavirus disease-19(COVID-19)patients are moderate cases who will recover with or without conventional treatment,while the remaining 20%developed severe disease requiring intensive care.1 Early and accurate screening of new COVID-19 patients to identify those who will develop severe disease will facilitate decision-making on appropriate treatment regimens and reasonable allocation of limited healthcare resources.Therefore,novel predictive factors for disease progress from moderate to severe are urgently needed. | Biao Di Hongling Jia Oscar Junhong Luo Fangqin Lin Kuibiao Li Yuanliang Zhang Huadong Wang Huiying Liang Jun Fan Zhicong Yang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 11 | The complete and fully-phased diploid genome of a male Han Chinese显示文摘Since the release of the complete human genome,the priority of human genomic study has now been shifting towards closing gaps in ethnic diversity.Here,we present a fully phased and well-annotated diploid human genome from a Han Chinese male individual(CN1),in which the assemblies of both haploids achieve the telomere-to-telomere(T2T)level.Comparison of this diploid genome with the CHM13 haploid T2T genome revealed significant variations in the centromere.Outside the centromere,we discovered 11,413 structural variations,including numerous novel ones.We also detected thousands of CN1 alleles that have accumulated high substitution rates and a few that have been under positive selection in the East Asian population.Further,we found that CN1 outperforms CHM13 as a reference genome in mapping and variant calling for the East Asian population owing to the distinct structural variants of the two references.Comparison of SNP calling for a large cohort of 8869 Chinese genomes using CN1 and CHM13 as reference respectively showed that the reference bias profoundly impacts rare SNP calling,with nearly 2 million rare SNPs miss-called with different reference genomes.Finally,applying the CN1 as a reference,we discovered 5.80 Mb and 4.21 Mb putative introgression sequences from Neanderthal and Denisovan,respectively,including many East Asian specific ones undetected using CHM13 as the reference.Our analyses reveal the advances of using CN1 as a reference for population genomic studies and paleo-genomic studies.This complete genome will serve as an alternative reference for future genomic studies on the East Asian population. | Chentao Yang Yang Zhou Yanni Song Dongya Wu Yan Zeng Lei Nie Panhong Liu Shilong Zhang Guangji Chen Jinjin Xu Hongling Zhou Long Zhou Xiaobo Qian Chenlu Liu Shangjin Tan Chengran Zhou Wei Dai Mengyang Xu Yanwei Qi Xiaobo Wang Lidong Guo Guangyi Fan Aijun Wang Yuan Deng Yong Zhang Jiazheng Jin Yunqiu He Chunxue Guo Guoji Guo Qing Zhou Xun Xu Huanming Yang Jian Wang Shuhua Xu Yafei Mao Xin Jin Jue Ruan Guojie Zhang | 2023 | Cell Research2023，33，10： | 0 |
| 12 | Psychological Cognition of Women of Childbearing Age on the Use of Cosmetics During Pregnancy显示文摘Objective:To investigate the psychological cognition of women of childbearing age on the use of cosmetics during pregnancy,so as to provide guidance for women of childbearing age to correctly use cosmetics during pregnancy.Methods:A total of 180 women of childbearing age who underwent gynecological examination in Dezhou People’s Hospital from October 2020 to October 2021 were selected as the research subjects.Questionnaires were used to investigate the psychological cognition of women of childbearing age on the use of cosmetics during pregnancy.Results:Among the 180 women of childbearing age,48(26.67%)felt that cosmetics cannot be used during pregnancy,60(33.33%)felt that it did not matter,and 72(40.00%)agreed that cosmetics can be used during pregnancy.In addition,urban women,highly educated women,unmarried women,and enterprise employees agreed with the use of special cosmetics for pregnant women or the selective use of cosmetics during pregnancy.Conclusion:Most women of child-bearing age felt that cosmetics can be used during pregnancy;this cognition is related to their education level,occupation,and registered residence. | Jing Huo Hongling Fan Hui Liu Chunjing Zhao Xiuli Hou | 2021 | Journal of Contemporary Educational Research2021，5，11： | 0 |
| 13 | A snapshot of the Chinese SOL Project显示文摘In 2003, the International Solanaceae Project (SOL) was initiated by an international consortium of ten countries including Korea, China, the United Kingdom, India, the Netherlands, France, Japan, Spain, Italy and the United States. The first major effort of the SOL aimed to produce a DNA sequence map for euchromatin regions of 12 chromosomes of tomato (Solanum lycopersicum) before 2010. Here we present an update on Chinese effort for sequencing the euchromatin region of chromosome 3. | Changbao Li Jiuhai Zhao Hongling Jiang Yu Geng Yuanyuan Dai Huajie Fan Dongfen Zhang Jinfeng Chen Fei Lu Jinfeng Shi Shouhong Sun Jianjun Chen Xiaohua Yang Chen Lu Mingsheng Chen Zhukuan Cheng Hongqing Ling Ying Wang Yongbiao Xue Chuanyou Li | 2008 | Journal of Genetics and Genomics2008，35，7： | 0 |
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