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| 1 | Chemical formation and source apportionment of PM_(2.5) at an urban site at the southern foot of the Taihang mountains显示文摘The region along the Taihang Mountains in the North China Plain(NCP) is characterized by serious fine particle pollution. To clarify the formation mechanism and controlling factors, an observational study was conducted to investigate the physical and chemical properties of the fine particulate matter in Jiaozuo city, China. Mass concentrations of the water-soluble ions(WSIs) in PM_(2.5) and gaseous pollutant precursors were measured on an hourly basis from December 1, 2017, to February 27, 2018. The positive matrix factorization(PMF) method and the FLEXible PARTicle(FLEXPART) model were employed to identify the sources of PM_(2.5). The results showed that the average mass concentration of PM_(2.5) was 111 μg/m^(3) during the observation period. Among the major WSIs, sulfate, nitrate, and ammonium(SNA) constituted 62% of the total PM_(2.5) mass, and NO_(3)^(-) ranked the highest with an average contribution of 24.6%. NH_(4)^(+) was abundant in most cases in Jiaozuo. According to chemical balance analysis, SO_(2)-4, NO_(3)^(-), and Cl^(-) might be present in the form of(NH_4)_(2)SO_4, NH_4NO_3, NH_4Cl, and KCl. The liquid-phase oxidation of SO_(2) and NO_(2) was severe during the haze period. The relative humidity and pH were the key factors influencing SO_(4)^(2-) formation. We found that NO_(3)^(-) mainly stemmed from homogeneous gas-phase reactions in the daytime and originated from the hydrolysis of N_(2)O_5 in the nighttime, which was inconsistent with previous studies. The PMF model identified five sources of PM_(2.5) : secondary origin(37.8%), vehicular emissions(34.7%), biomass burning(11.5%), coal combustion(9.4%), and crustal dust(6.6%). | Xiaoyong Liu Mingshi Wang Xiaole Pan Xiyue Wang Xiaolong Yue Donghui Zhang Zhigang Ma Yu Tian Hang Liu Shandong Lei Yuting Zhang Qi Liao Baozhu Ge Dawei Wang Jie Li Yele Sun Pingqing Fu Zifa Wang Hong He | 2021 | Journal of Environmental Sciences2021，33，5： | 5 |
| 2 | Study on the Control Strategy of Free Piston Expander-Linear Generator Used for Organic Rankine Cycle Waste Heat Recovery显示文摘This study presents a free piston expander-linear generator (FPE-LG) for engine waste heat recovery.The control strategies based on displacement (control strategy A) and valve timings (control strategy B) are proposed.The operation and output characteristics with different control strategies are conducted.The results show that control strategy has significant effect on the FPE-LG performance.When FPE-LG operates with control strategy A,the operation frequency is determined by the intake pressure,advanced exhaust duration,fixed position point and external load resistance,whereas it is only related with the intake/exhaust time and advanced exhaust duration (ta) for control strategy B.The external load resistance has slight influence on the stroke length for these two control strategies.For control strategy A,when advanced exhaust duration is more than 40 ms,the stroke length rises with the intake pressure,whereas it first rises and then reduces when advanced exhaust duration is less than 40 ms.There exist the optimal external load resistance and advanced exhaust duration to achieve the maximum power output with control strategy A,whereas the average power output reduces with the increasing advanced exhaust duration when using control strategy B.Stable operation and high power output can be obtained by using different control strategies and adjusting relevant operation parameters. | HOU Xiaochen ZHANG Hongguang ZHAO Tenglong SHI Xin XU Yonghong LI Jian GE Zhong ZHANG Jun WU Yuting | 2021 | Journal of Thermal Science2021，30，2： | 1 |
| 3 | Enhanced therapeutic efficacy of vitamin K2 by silencing BCL-2 expressionin SMMC-7721 hepatocellular carcinoma cells显示文摘 | Yuting Yao Lu Li He Zhang Renbing Jia Bo Liu Xiaoping Zhao Leilei Zhang Guanxiang Qian Xianqun Fan Shengfang Ge | 2012 | Oncology Letters2012，，1： | 1 |
| 4 | Transport Patterns and Potential Sources of Atmospheric Pollution during the ⅩⅩⅣ Olympic Winter Games Period显示文摘The attainment of suitable ambient air quality standards is a matter of great concern for successfully hosting the ⅩⅩⅣ Olympic Winter Games(OWG). Transport patterns and potential sources of pollutants in Zhangjiakou(ZJK) were investigated using pollutant monitoring datasets and a dispersion model. The PM_(2.5) concentration during February in ZJK has increased slightly(28%) from 2018 to 2021, mostly owing to the shift of main potential source regions of west-central Inner Mongolia and Mongolian areas(2015–18) to the North China Plain and northern Shanxi Province(NCPS) after 2018.Using CO as an indicator, the relative contributions of the different regions to the receptor site(ZJK) were evaluated based on the source-receptor-relationship method(SRR) and an emission inventory. We found that the relative contribution of pollutants from NCPS increased from 33% to 68% during 2019–21. Central Inner Mongolia(CIM) also has an important impact on ZJK under unfavorable weather conditions. This study demonstrated that the effect of pollution control measures in the NCPS and CIM should be strengthened to ensure that the air quality meets the standard during the ⅩⅩⅣ OWG. | Yuting ZHANG Xiaole PAN Yu TIAN Hang LIU Xueshun CHEN Baozhu GE Zhe WANG Xiao TANG Shandong LEI Weijie YAO Yuanzhe REN Yongli TIAN Jie LI Pingqing FU Jinyuan XIN Yele SUN Junji CAO Zifa WANG | 2022 | Advances in Atmospheric Sciences2022，39，10： | 1 |
| 5 | IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent STAT3-K631 acetylation and its Y705-phosphorylation显示文摘The cancer cell metastasis is a major death reason for patients with non-small cell lung cancer(NSCLC).Although researchers have disclosed that interleukin 17(IL-17)can increase matrix metalloproteinases(MMPs)induction causing NSCLC cell metastasis,the underlying mechanism remains unclear.In the study,we found that IL-17 receptor A(IL-17RA),p300,p-STAT3,Ack-STAT3,and MMP19 were up-regulated both in NSCLC tissues and NSCLC cells stimulated with IL-17.p300,STAT3 and MMP19 overexpression or knockdown could raise or reduce IL-17-induced p-STAT3,Ack-STAT3 and MMP19 level as well as the cell migration and invasion.Mechanism investigation revealed that STAT3 and p300 bound to the same region(−544 to−389 nt)of MMP19 promoter,and p300 could acetylate STAT3-K631 elevating STAT3 transcriptional activity,p-STAT3 or MMP19 expression and the cell mobility exposed to IL-17.Meanwhile,p300-mediated STAT3-K631 acetylation and its Y705-phosphorylation could interact,synergistically facilitating MMP19 gene transcription and enhancing cell migration and invasion.Besides,the animal experiments exhibited that the nude mice inoculated with NSCLC cells by silencing p300,STAT3 or MMP19 gene plus IL-17 treatment,the nodule number,and MMP19,Ack-STAT3,or p-STAT3 production in the lung metastatic nodules were all alleviated.Collectively,these outcomes uncover that IL-17-triggered NSCLC metastasis involves up-regulating MMP19 expression via the interaction of STAT3-K631 acetylation by p300 and its Y705-phosphorylation,which provides a new mechanistic insight and potential strategy for NSCLC metastasis and therapy. | WEN GE YA LI YUTING RUAN NINGXIA WU PEI MA TONGPENG XU YONGQIAN SHU YINGWEI WANG WEN QIU CHENHUI ZHAO | 2024 | Oncology Research2024，32，4： | 0 |
| 6 | Near-surface structure from ambient-noise tomography and horizontal-to-vertical spectral ratio beneath the Nankou-Sunhe fault显示文摘Active faults pose a great threat to urban security.As the largest NW-trend active fault in Beijing area,the Nankou-Sunhe fault plays an important role in earthquake disaster and city construction.In this study,we collect continuous ambient noise data recorded by 43 temporary short-period seismograph between September 21th to October 12th 2019 to investigate the near-surface structure beneath the Nankou-Sunhe fault by using ambient noise tomography(ANT)and horizontal-to-vertical spectral ratio(HVSR)method.From ambient noise processing,fundamental-mode Rayleigh wave signals are clearly observed in the frequency band of 0.4-2.5 Hz.Then direct surface-wave inversion algorithm is applied to calculate the 3D shear-wave velocity model.Our results show that there is a sharp velocity contrast across the Nankou-Sunhe fault,with low velocities down to about 2 km on the hanging wall and high velocity on the footwall of the fault.According to the geological investigation,the low velocities are related to thicker sediments and Jurassic volcanic rock below which are the cap rock of the hydrothermal system.From the HVSR analysis,the HVSR curves of the sites near the fault shows double-peak,one less than 1 Hz and the other centered 7 Hz.After converting frequency to depth by the empirical equation,the results show that the thickness of sediments is thinned from southwest to northeast,which generally agrees well to field survey.Our results provide high-resolution near-surface structure for future study on disaster risk reduction and urban planning. | Yuting Zhang Hongyi Li Yanzhen Li Zhijie Wei Zeyu Ma Huiying Ge Tongli Wang Yafen Huang Min Liu | 2020 | Earthquake Science2020，33，5： | 0 |
| 7 | Refractory black carbon aerosols in rainwater in the summer of 2019 in Beijing:Mass concentration,size distribution and wet scavenging ratio显示文摘Black carbon(BC)aerosols in the atmosphere play a significant role in climate systems due to their strong ability to absorb solar radiation.The lifetime of BC depends on atmospheric transport,aging and consequently on wet scavenging processes(in-cloud and below-cloud scavenging).In this study,sequential rainwater samples in eight rainfall events collected in 2 mm interval were measured by a tandem system including a single particle soot photometer(SP2)and a nebulizer.The results showed that the volume-weighted average(VWA)mass concentrations of refractory black carbon(rBC)in each rainfall event varied,ranging from 10.8 to 78.9μg/L.The highest rBC concentrations in the rainwater samples typically occurred in the first fraction from individual rainfall events.The geometric mean median mass-equivalent diameter(MMD)decreased under precipitation,indicating that rBC with larger sizes was relatively aged and preferentially removed by wet scavenging.A positive correlation(R2=0.73)between the VWA mass concentrations of rBC in rainwater and that in ambient air suggested the important contribution of scavenging process.Additionally,the contributions of in-cloud and below-cloud scavenging were distinguished and accounted for 74%and 26%to wet scavenging,respectively.The scavenging ratio of rBC particles was estimated to be 0.06 on average.This study provides helpful information for better understanding the mechanism of rBC wet scavenging and reducing the uncertainty of numerical simulations of the climate effects of rBC. | Shandong Lei Baozhu Ge Hang Liu Jiannong Quan Danhui Xu Yuting Zhang Weijie Yao Lu Lei Yu Tian Qi Liao Xiaoyong Liu Jie Li Jinyuan Xin Yele Sun Pingqing Fu Junji Cao Zifa Wang Xiaole Pan | 2023 | Journal of Environmental Sciences2023，，10： | 0 |
| 8 | A genome-wide association study of lateral root number for Asian cotton(Gossypium arboreum L.)显示文摘Background:The lateral root is one of the most important organs that constitute the root architecture system in plants.It can directly affect the contact area between plants and soil and plays an important role in plant structural support and nutrient absorption.Optimizing root architecture systems can greatly increase crop yields.This study was designed to identify the molecular markers and candidate genes associated with lateral root development in cotton and to evaluate correlations with yield and disease traits.Result:The number of lateral roots for 14-day old seedlings was recorded for 215 Gossypium arboreum accessions.A correlation analysis showed that the number of lateral roots positively correlates with the sympodial branch node and seed index traits,but negatively correlates with lint percentage.A Genome-wide association study(GWAS)identified 18 significant SNPs with 19 candidate genes associated with the lateral root number.Expression analysis identified three genes(FLA 12,WRKY29,and RBOHA)associated with lateral root development.Conclusion:GWAS an alysis identified key SNPs and candidate gen esfor lateral root number,a nd gen es of FLA 12,WRKY29,and RBOHA may play a pivotal role in lateral root development in Asian cotton. | HU Daowu HE Shoupu SUN Gaofei JIA Yinhua GENG Xiaoli WANG Liru PAN Zhaoe CHEN Baojun LI Hongge ZUBAIR Iqbal WANG Xiaoyang ZHAO Zibo GE Yuting PANG Baoyin DU Xiongming | 2022 | Journal of Cotton Research2022，5，2： | 0 |
| 9 | Determination of the half-life of^(91)Sr in uranium sample bombarded by 14.8 MeV neutron显示文摘Purpose Due to the few reports on the^(91)Sr half-life previously,the accuracy and uncertainty of the results are difficult to meet the requirements such as calculating the cross section and thefission yields of 235U,238U,and 239Pu.To solve the discrepancy of^(91)Sr half-life in existing experimental data,the half-life of^(91)Sr was measured in this work,and the uncertainty was discussed in detail.Method The measurements were performed by the activation method implemented for the uranium sample using the K-400 neutron generator at the Chinese Academy of Engineering Physics(CAEP).The half-life of^(91)Sr was measured byγ-ray spectrometry using the high-resolution High Purity Germanium(HPGe)Detector.Results Through exponential functionfitting and a detailed discussion of the uncertainty evaluation,the half-life of^(91)Sr in the present work was determined to be 9.65±0.30 h,which was consistent with the values reported previously and the uncertainty was reduced greatly,however,the uncertainty assessment of the latter was barely documented.Conclusions In this work,a more accurate measurement of the^(91)Sr half-life is provided,as well as the uncertainty is discussed in detail.This result will provide essential information for applications using an activation method,such as the calculation offission yields of 235U,238U,and 239Pu. | Yuting Wei Changlin Lan Li Feng Chao Xu Xianlin Yang Xiaojun Li Jiahao Wang Yujie Ge Benchao Lou Li Jiang | 2022 | Radiation Detection Technology and Methods2022，6，3： | 0 |
| 10 | Multi-View & Transfer Learning for Epilepsy Recognition Based on EEG Signals显示文摘Epilepsy is a central nervous system disorder in which brain activity becomes abnormal.Electroencephalogram(EEG)signals,as recordings of brain activity,have been widely used for epilepsy recognition.To study epilep-tic EEG signals and develop artificial intelligence(AI)-assist recognition,a multi-view transfer learning(MVTL-LSR)algorithm based on least squares regression is proposed in this study.Compared with most existing multi-view transfer learning algorithms,MVTL-LSR has two merits:(1)Since traditional transfer learning algorithms leverage knowledge from different sources,which poses a significant risk to data privacy.Therefore,we develop a knowledge transfer mechanism that can protect the security of source domain data while guaranteeing performance.(2)When utilizing multi-view data,we embed view weighting and manifold regularization into the transfer framework to measure the views’strengths and weaknesses and improve generalization ability.In the experimental studies,12 different simulated multi-view&transfer scenarios are constructed from epileptic EEG signals licensed and provided by the Uni-versity of Bonn,Germany.Extensive experimental results show that MVTL-LSR outperforms baselines.The source code will be available on http://gffzz188fe103f8f1460asp990pkkb9xwx65wf.ffgz.tsg.suse.edu.cn/didid5/MVTL-LSR. | Jiali Wang Bing Li Chengyu Qiu Xinyun Zhang Yuting Cheng Peihua Wang Ta Zhou Hong Ge Yuanpeng Zhang Jing Cai | 2023 | Computers, Materials & Continua2023，，6： | 0 |
| 11 | A novel synthesized prodrug of gemcitabine based on oxygen-free radical sensitivity inhibited the growth of lung cancer cells显示文摘In the present study,we introduced the H2O2-sensitive thiazolidinone moiety at the 4th amino group of gemcitabine(GEM)to synthesize a new target compound named GEM-ZZQ,and then we confirmed its chemical structure by nuclear magnetic resonance spectroscopy.We further confirmed that GEM-ZZQ had a good chemical stability in different pH solutions in vitro and that it could be activated by H2O2 to release GEM.Pharmacodynamic studies revealed that the growth inhibition of human normal epithelial cells was weaker by GEM-ZZQ than by GEM treatment and that the inhibition of various lung cancer cell lines by GEM-ZZQ was similar to that of GEM.For the lung cancer cell lines that are resistant to the epidermal growth factor receptor(EGFR)-targeting inhibitor osimertinib,GEM-ZZQ showed less growth inhibition than GEM;however,GEM-ZZQ in combination with cisplatin showed better synergistic effects than GEM in the low-dose groups.In summary,we provided a new anti-cancer compound GEM-ZZQ for treating lung cancer by modifying the GEM structure. | Xinlu Chai Yuting Meng Wei Ge Juan Wang Fei Li Xue Jun Wang Xuerong Wang | 2023 | The Journal of Biomedical Research2023，37，5： | 0 |
| 12 | Sustainable Mining in the Era of Artificial Intelligence显示文摘The mining sector historically drove the global economy but at the expense of severe environmental and health repercussions,posing sustainability challenges[1]-[3].Recent advancements on artificial intelligence(AI)are revolutionizing mining through robotic and data-driven innovations[4]-[7].While AI offers mining industry advantages,it is crucial to acknowledge the potential risks associated with its widespread use.Over-reliance on AI may lead to a loss of human control over mining operations in the future,resulting in unpredictable consequences. | Long Chen Yuting Xie Yutong Wang Shirong Ge Fei-Yue Wang | 2024 | IEEE/CAA Journal of Automatica Sinica2024，11，1： | 0 |
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