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| 1 | Anti-hepatoma activity and mechanism of ursolic acid and its derivatives isolated from Aralia decaisneana显示文摘瞄准:为了调查 ursolic (UA ) 和它的衍生物的反肿瘤活动,在肝细胞癌上从美┦木孤立 decaisneana 在试管内和在活体内。方法:在活体内细胞毒性被 3- 首先屏蔽[4,5-dimethylthiazol-2-yl ]-2, 5-diphenyltetrazolium 溴化物(MTT ) 试金。词法观察, DNA 梯子,流动血细胞计数分析,西方的污点和实时 PCR 被采用阐明 UA 的细胞毒素的机制。植入的老鼠肝细胞瘤 H22 被用来评估生长 UA 的禁止的效果在活体内。结果:UA 能显著地禁止 HepG2 和它的药抵抗的增长紧张, R-HepG2 房间,而是首先有教养的正常老鼠 hepatocytes 上的有的不禁止的效果而 UA 的所有六衍生物不能禁止所有的生长,测试房间排队。机制上的进一步的学习证明那 apoptosis 和 G0/G1 拘捕涉及多(自动数据处理核糖) 的细胞毒性和劈开聚合酶(PARP ) 。cyclooxygenase-2 (COX-2 ) 的 Downregulation 蛋白质并且在热吃惊蛋白质(HSP ) 的规定上面, 105 mRNA 相关到与 UA 对待的 HepG2 房间的 apoptosis。另外, UA 能也禁止 H22 肝细胞瘤在活体内的生长。结论:UA 是一个有希望的反肿瘤代理人,但是推进工作需要被做改进它的溶解度。 | Ze Tian Geng Lin Rui-Xia Zheng Feng Huang Meng-Su Yang Pei-Gen Xiao | 2006 | World Journal of Gastroenterology2006，12，6： | 31 |
| 2 | Efficient and stable planar all-inorganic perovskite solar cells based on high-quality CsPbBr3 films with controllable morphology显示文摘All-inorganic cesium lead bromide(CsPbBr3)perovskite is attracting growing interest as functional materials in photovoltaics and other optoelectronic devices due to its superb stability.However,the fabrication of high-quality CsPbBr3 films still remains a big challenge by solution-process because of the low solubility of the cesium precursor in common solvents.Herein,we report a facile solution-processed approach to prepare high-quality CsPbBr3 perovskite films via a two-step spin-coating method,in which the Cs Br methanol/H2 O mixed solvent solution is spin-coated onto the lead bromide films,followed by an isopropanol-assisted post-treatment to regulate the crystallization process and to control the film morphology.In this fashion,dense and uniform CsPbBr3 films are obtained consisting of large crystalline domains with sizes up to microns and low defect density.The effectiveness of the resulting CsPbBr3 films is further examined in perovskite solar cells(PSCs)with a simplified planar architecture of fluorine–doped tin oxide/compact Ti O2/CsPbBr3/carbon,which deliver a maximum power conversion efficiency of 8.11%together with excellent thermal and humidity stability.The present work offers a simple and effective strategy in fabrication of high-quality CsPbBr3 films for efficient and stable PSCs as well as other optoelectronic devices. | Xiaojing Wan Ze Yu Wenming Tian Fuzhi Huang Shengye Jin Xichuan Yang Yi-Bing Cheng Anders Hagfeldt Licheng Sun | 2020 | Journal of Energy Chemistry2020，29，7： | 6 |
| 3 | Xinglou Chengqi Decoction improves neurological function in experimental stroke mice as evidenced by gut microbiota analysis and network pharmacology显示文摘The current study was designed to explore the brain protection mechanism of Xinglou Chengqi Decoction(XCD)based on gut microbiota analysis and network pharmacology. A transient middle cerebral artery occlusion(MCAO) model of mice was established, followed by behavioral evaluation, TTC and TUNEL staining. Additionally, to investigate the effects of gut microbiota on neurological function after stroke, C57BL/6 mice were treated with anti-biotic cocktails 14 days prior to ischemic stroke(IS) to deplete the gut microbiota. High-throughput 16S rDNA gene sequencing, metabonomics technique, and flow multifactor technology were used to analyze bacterial communities, SCFAs and inflammatory cytokines respectively. Finally, as a supplement, network pharmacology and molecular docking were applied to fully explore the multicomponent-multitarget-multichannel mechanism of XCD in treating IS, implicated in ADME screening, target identification, network analysis, functional annotation, and pathway enrichment analysis.We found that XCD effectively improved neurological function, relieved cerebral infarction and decreased the neuronal apoptosis.Moreover, XCD promoted the release of anti-inflammatory factor like IL-10, while down-regulating pro-inflammatory factors such as TNF-α, IL-17A, and IL-22. Furthermore, XCD significantly increased the levels of short chain fatty acids(SCFAs), especially butyric acid. The mechanism might be related to the regulation of SCFAs-producing bacteria like Verrucomicrobia and Akkermansia, and bacteria that regulate inflammation like Paraprevotella, Roseburia, Streptophyta and Enterococcu. Finally, in the network pharmacological analysis, 51 active compounds in XCD and 44 intersection targets of IS and XCD were selected. As a validation, components in XCD docked well with key targets. It was obviously that biological processes were mainly involved in the regulation of apoptotic process, inflammatory response, response to fatty acid, and regulation of establishment of endothelial barrier in GO enrichment. XCD can improve neurological function in experimental stroke mice, partly due to the regulation of gut microbiota. Besises, XCD has the characteristic of 'multi-component, multi-target and multi-channel' in the treatment of IS revealed by network pharmacology and molecular docking. | GAO Qiang HAN Zhen-Yun TIAN Dan-Feng LIU Gan-Lu WANG Zhen-Yi LIN Jing-Feng CHANG Ze ZHANG Dan-Dan XIE Ying-Zhen SUN Yi-Kun YAO Xing-Wei MA Da-Yong | 2021 | Chinese Journal of Natural Medicines2021，19，12： | 6 |
| 4 | Syntheses, structures and magnetic properties of three Co(Ⅱ)coordination architectures based on a flexible multidentate carboxylate ligand and different N-donor ligands显示文摘Three new cobalt complexes,{[Co5(tci)2(bimb)3(3-O)2(H2O)2]·3DMF·4H2O}n(1),{[Co3(tci)2(bib)]·2DMF·2H2O}n(2)and{[Co(Htci)(bpea)0.5]·H2O}n(3)(H3tci=tris(2-carboxyethyl)isocyanurate,bimb=4,4′-bis(imidazol-1-yl)biphenyl,bib=1,4-bis(imidazol-1-yl)benzene,bpea=1,2-bis(4-pyridyl)ethane,DMF=N,N′-dimethylformamide),have been successfully synthesized through the assembly of Co(II)ions,H3tci and different N-donor ligands,respectively.All complexes were structurally characterized by single crystal X-ray diffraction,elemental analyses,IR spectra,thermogravimetric(TG)analyses and X-ray powder diffraction(XRPD).Complex 1 exhibits a 3D three-fold parallel interpenetrated 3D→3D structure with(65·8)CdSO4topology.Complex 2 is built from[Co3(2-Ocarboxyl)2(CO2)4]clusters and linear bib ligands,displaying a two-fold parallel interpenetrated(3,8)-connected(43)2(46·618·84)topology,while complex 3 is a 3D pillar-layered structure involving an infinite–Co–(2-Ocarboxyl)(CO2)–Co–chain.The diverse structures of the three complexes indicate that the skeletons of different N-donor ligands play an important role in the assembly of such different frameworks.In addition,magnetic investigation indicates that besides spin-orbit coupling of Co(II)ions,there exist antiferromagnetic exchange interactions in Co5and Co3clusters of 1 and 2,respectively. | TIAN Dan LIU SuiJun ZHANG DaShuai CHANG Ze HU TongLiang BU XianHe | 2013 | Science China Chemistry2013，56，12： | 5 |
| 5 | Spatio-temporal variation in rock exhumation linked to large-scale shear zones in the southeastern Tibetan Plateau显示文摘Crustal-scale shear zones are believed to have played an important role in the tectonic and landscape evolution of orogens. However, the variation of long-term rock exhumation between the interior of shear zones and adjacent regions has not been documented in detail. In this study, we obtained new zircon U-Pb, biotite ^(40)Ar/^(39)Ar, zircon and apatite(U-Th)/He data, and conducted inverse thermal history modeling from two age-elevation profiles(the Pianma and Tu'er profiles) in the southeastern Tibetan Plateau. Our goal is to constrain the exhumation history of the Gaoligong and Chongshan shear zones and adjacent regions, so as to explore the effect of the shear zones on exhumation and their thermal effect on cooling that should not be ignored. Our results suggest that during the interval of 18–11 Ma the exhumation rates of rocks within the Gaoligong shear zone are anomalously high compared with those outside of. The rapid cooling during 18–11 Ma appears to be restricted to the shear zone, likely due to localized thermal effects of shearing and exhumation. After 11 Ma, both the areas within and outside of the shear zones experienced a similar two-stage exhumation history: slower cooling until the early Pliocene, and then a rapid increase in cooling rate since the early Pliocene. Our results indicate a synchronized exhumation but with spatially varied exhumation rates. Our study also highlights the important role of large-scale shear zones in exposing rocks, and thus the importance of the structural context when interpreting thermochronological data in the southeastern margin of the Tibetan Plateau. | Yukui GE Jing LIU-ZENG Jinyu ZHANG Wei WANG Yuntao TIAN Matthew FOX Lingsen ZENG Xiaoming SHEN Heng WANG Ze SU Kejia XIE | 2020 | Science China Earth Sciences2020，63，4： | 5 |
| 6 | Microstructure,tensile properties and thermal stability of AlMgSiScZr alloy printed by laser powder bed fusion显示文摘The new generation of Sc and Zr modified Al alloys has been attracted wide concerns in aerospace industry,owing to the excellent mechanical performances and superior thermal stability than other normal Al alloys.By microalloying with Sc and Zr,the Al3(Sc,Zr)particle forms as the grain refiner during the solidification,which is extremely beneficial for the laser powder bed fusion(LPBF)processed Al alloys.In this study,a new type Al-14.1 Mg-0.47 Si-0.31 Sc-0.17 Zr alloy was additively manufactured by LPBF,and the microstructure,tensile properties and thermal stability were studied in detail.By using a single melt-67°scanning strategy,the LPBF-processed specimen with a relative density of 99.4%and tensile strength of 487.7 MPa was obtained at 160 W-200 mm/s.And this AlMgSiScZr alloy can still exhibit an excellent tensile strength of 393.9 MPa at a moderate temperature of 473 K.After the aging treatment,the tensile properties further increased due to the precipitate hardening of Mg2Si and Al3(Sc,Zr),and the maximum value(580 MPa)was reached at an aging time of 10 h.The average crystal size was almost unchanged after aging treated at 325℃and 24 h,indicating this AlMgSiScZr alloy has an improved thermal stability.The AlMgSiScZr alloy is recommended to substitute some particular titanium alloys in aerospace field afterwards. | Jiang Bi Zhenglong Lei Yanbin Chen Xi Chen Ze Tian Nannan Lu Xikun Qin Jingwei Liang | 2021 | Journal of Materials Science & Technology2021，，10： | 4 |
| 7 | Back-n white neutron source at CSNS and its applications显示文摘Back-streaming neutrons from the spallation target of the China Spallation Neutron Source(CSNS)that emit through the incoming proton channel were exploited to build a white neutron beam facility(the so-called Back-n white neutron source),which was completed in March 2018.The Back-n neutron beam is very intense,at approximately 29107 n/cm2/s at 55 m from the target,and has a nominal proton beam with a power of 100 kW in the CSNS-I phase and a kinetic energy of 1.6 GeV and a thick tungsten target in multiple slices with modest moderation from the cooling water through the slices.In addition,the excellent energy spectrum spanning from 0.5 eV to 200 MeV,and a good time resolution related tothe time-of-flight measurements make it a typical white neutron source for nuclear data measurements;its overall performance is among that of the best white neutron sources in the world.Equipped with advanced spectrometers,detectors,and application utilities,the Back-n facility can serve wide applications,with a focus on neutron-induced cross-sectional measurements.This article presents an overview of the neutron beam characteristics,the experimental setups,and the ongoing applications at Backn. | Jing-Yu Tang Qi An Jiang-Bo Bai Jie Bao Yu Bao Ping Cao Hao-Lei Chen Qi-Ping Chen Yong-Hao Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Rong Liu Shu-Bin Liu Xing-Yan Liu Ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Xin-Yi Tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Yi-Wei Yang Han Yi Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu 无 | 2021 | Nuclear Science and Techniques2021，32，1： | 4 |
| 8 | The Ternary Goldbach Problem with Primes in Arithmetic Progressions | Zhen Feng ZHANG Tian Ze WANG State Key Laboratory of Information Security, Graduate School, Chinese Academy of Sciences, Beijing 100039, P. R. China Depariment of Mathematics, Henan University, Kaifeng 475001, P. R. China Department of Mathematics, Henan University, Kaifeng 475001, P. R. China | 2001 | Acta Mathematica Sinica,English Series2001，17，4： | 3 |
| 9 | First experimental constraints on WIMP couplings in the effective field theory framework from CDEX显示文摘We present weakly interacting massive particles(WIMPs) search results performed using two approaches of effective field theory from the China Dark Matter Experiment(CDEX), based on the data from both CDEX-1B and CDEX-10 stages. In the nonrelativistic effective field theory approach, both time-integrated and annual modulation analyses were used to set new limits for the coupling of WIMP-nucleon effective operators at 90% confidence level(C.L.) and improve over the current bounds in the low mχregion. In the chiral effective field theory approach, data from CDEX-10 were used to set an upper limit on WIMP-pion coupling at 90% C.L. We for the first time extended the limit to the m_(χ)<6 GeV/c^(2) region. | Yi Wang Zhi Zeng Qian Yue LiTao Yang KeJun Kang YuanJing Li Mehment Agartioglu HaiPeng An JianPing Chang JingHan Chen YunHua Chen JianPing Cheng Cheng Yi Chiang WenHan Dai Zhi Deng ChangHao Fang XinPing Geng Hui Gong QiuJu Guo XuYuan Guo HongJian He Li He ShengMing He JinWei Hu TuChen Huang HanXiong Huang HaiTao Jia LiPing Jia Xi Jiang HauBin Li JianMin Li Jin Li MingXuan Li RenMingJie Li Xia Li YuLan Li Bin Liao FongKay Lin ShinTed Lin ShuKui Liu YanDong Liu Yu Liu YuanYuan Liu ZhongZhi Liu Hao Ma YuCai Mao QiYuan Nie JinHua Ning Hui Pan NingChun Qi Jie Ren XiChao Ruan ChangSong Shang Vivek Sharma Ze She Lakhwinder Singh Monoj Kumar Singh TianXi Sun ChangJian Tang WeiYou Tang Yang Tian GuangFu Wang Li Wang Qing Wang Yu Chen Wang YunXiang Wang Zhen Wang Henry Tsz-King Wong ShiYong Wu YuCheng Wu HaoYang Xing Yin Xu Tao Xue YuLu Yan Nan Yi ChunXu Yu HaiJun Yu JianFeng Yue Ming Zeng BingTao Zhang Lei Zhang FengShou Zhang ZhenYu Zhang KangKang Zhao MingGang Zhao JiFang Zhou ZuYing Zhou JingJun Zhu | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，8： | 3 |
| 10 | Optimal Waist Circumference Cut-off values for Identifying Metabolic Risk Factors in Middle-aged and Elderly Subjects in Shandong Province of China显示文摘Objective To study the optimal waist circumference(WC) cut-off values for identifying metabolic risk factors in middle-aged and elderly subjects in Shandong Province of China. Methods A total of 2 873 men and 5 559 women were included in this cross-sectional study. Metabolic syndrome(MetS) was diagnosed according to the definition of Chinese Diabetes Society in 2004. The relation between WC and MetS was analyzed by multivariate logistic regression analysis. The optimal WC cut-off values were identified using the area under the ROC curve and the different diagnostic criteria for central obesity were compared. Results The WC was the risk factor for MetS independent of BMI, blood glucose, blood lipid, and blood pressure. The optimal WC cut-off value was 83.8 cm and 91.1 cm for identifying MetS in women and men, respectively. Compared with 80 cm and 85 cm for women and men, 85 cm and 90 cm had a higher Youden index for identifying all metabolic risk factors and MetS in women and men. Conclusion The appropriate WC cut-off value is 85 cm and 90 cm for identifying central obesity and MetS in women and men in Shandong Province of China. | HOU Xin Guo WANG Chuan MA Ze Qiang YANG Wei Fang WANG Ji Xiang LI Cheng Qiao WANG Yu Lian LIU Shu Min Hu Xiu Ping ZHANG Xiu Ping JIANG Mei WANG Wei Qing NING Guang ZHENG Hui Zhen MA Ai Xia SUN Yu SONG Jun LIN Peng LIANG Kai LIU Fu Qiang LI Wen Juan XIAO Juan GONG Lei WANG Mei Jian LIU Ji Dong YAN Fei YANG Jun Peng WANG Ling Shu TIAN Meng ZHAO Ru Xing JIANG Ling CHEN Li | 2014 | Biomedical and Environmental Sciences2014，27，5： | 3 |
| 11 | Hierarchical grain size and nanotwin gradient microstructure for improved mechanical properties of a non-equiatomic CoCrFeMnNi high-entropy alloy显示文摘This study explored a multi-mechanism approach to improving the mechanical properties of a Co CrFe Mn Ni high-entropy alloy through non-equiatomic alloy design and processing.The alloy design ensures a single-phase face-centered cubic structure while lowering the stacking fault energy to encourage the formation of deformation twins and stacking faults by altering the equiatomic composition of the alloy.The processing strategy applied helped create a hierarchical grain size gradient microstructure with a high nanotwins population.This was achieved by means of rotationally accelerated shot peening(RASP).The non-equiatomic Co Cr Fe Mn Ni high-entropy alloy achieved a yield strength of 750 MPa,a tensile strength of 1050 MPa,and tensile uniform elongation of 27.5%.The toughness of the alloy was 2.53×10^(10)k J/m^(3),which is about 2 times that of the same alloy without the RASP treatment.The strength increase is attributed to the effects of grain boundary strengthening,dislocation strengthening,twin strengthening,and hetero-deformation strengthening associated with the heterogeneous microstructure of the alloy.The concurrent occurrence of the multiple deformation mechanisms,i.e.,dislocation deformation,twining deformation and microband deformation,contributes to achieving a suitable strain hardening of the alloy that helps to prevent early necking and to assure steady plastic deformation for high toughness. | Zibing An Shengcheng Mao Yinong Liu Hao Zhou Yadi Zhai Zhiyong Tian Cuixiu Liu Ze Zhang Xiaodong Han | 2021 | Journal of Materials Science & Technology2021，，33： | 3 |
| 12 | Atomic-scale mechanism of the θ’’→θ’ phase transformation in Al-Cu alloys显示文摘The phase transformation of θ’’→θ’ in an Al-5.7 Cu alloy was investigated by aberration-corrected scanning transmission electron microscopy, and the tranformation mode of θ’’→θ’ during aging treatment was clarified. In the presence of the θ’ phases, θ’ was found to be formed by in-situ transformation fromθ’’ with the same plate shape, size and broad faces. The transformation starts from multiple sites within the θ’ precipitate and the whole θ’ phase finally forms as the preferential θ’ sections grow and connect with each other. Antiphase domain boundaries are also found in some θ’ precipitates when the disregistry exists between different θ’ sections. | Zhenju Shen Qingqing Ding Chunhui Liu Jiangwei Wang He Tian Jixue Li Ze Zhang | 2017 | Journal of Materials Science & Technology2017，33，10： | 3 |
| 13 | Current Trends and Perspectives of Detection and Location for Buried Non-Metallic Pipelines显示文摘Buried pipelines are an essential component of the urban infrastructure of modern cities.Traditional buried pipes are mainly made of metal materials.With the development of material science and technology in recent years,non-metallic pipes,such as plastic pipes,ceramic pipes,and concrete pipes,are increasingly taking the place of pipes made from metal in various pipeline networks such as water supply,drainage,heat,industry,oil,and gas.The location technologies for the location of the buried metal pipeline have become mature,but detection and location technologies for the non-metallic pipelines are still developing.In this paper,current trends and future perspectives of detection and location of buried non-metallic pipelines are summarized.Initially,this paper reviews and analyzes electromagnetic induction technologies,electromagnetic wave technologies,and other physics-based technologies.It then focuses on acoustic detection and location technologies,and finally introduces emerging technologies.Then the technical characteristics of each detection and location method have been compared,with their strengths and weaknesses identified.The current trends and future perspectives of each buried non-metallic pipeline detection and location technology have also been defined.Finally,some suggestions for the future development of buried non-metallic pipeline detection and location technologies are provided. | Liang Ge Changpeng Zhang Guiyun Tian Xiaoting Xiao Junaid Ahmed Guohui Wei Ze Hu Ju Xiang Mark Robinson | 2021 | Chinese Journal of Mechanical Engineering2021，34，5： | 2 |
| 14 | A Platform to Improve Echinococcosis Control in Tibetan Populations-Sichuan Province,China,2015‒2020显示文摘Echinococcosis is a neglected parasitic zoonotic disease that is distributed worldwide.Previous data has shown that China holds the highest disease burden of echinococcosis in the world,resulting in 22.97×10^(5) disability adjusted life year(DALYs)lost annually(1).Echinococcosis is one of the epidemiological factors responsible for poverty in China.Since 2000,China’s central government(CG)has taken several actions to control echinococcosis in Western China.Since 2005. | Tian Tian Shuai Han Chuizhao Xue Xu Wang Shijie Yang Bo Zhong Qian Wang Wenjie Yu Sha Liao Dan Ba Ze Li Wei Li Fei Xie Qiang Wang Zelin Zhu Yuwan Hao Weiping Wu Ning Xiao Xiao-nong Zhou | 2021 | China CDC weekly2021，3，5： | 2 |
| 15 | An additively manufactured Al-14.1Mg-0.47Si-0.31Sc-0.17Zr alloy with high specific strength,good thermal stability and excellent corrosion resistance显示文摘A novel Al-14.1 Mg-0.47 Si-0.31 Sc-0.17 Zr alloy was applied in the printing process of selective laser melting(SLM),and the corresponding microstructural feature,phase identification,tensile properties and corrosion behavior of the Al Mg Si Sc Zr alloy were studied in detail.As fabricated at 160 W and 200 mm/s,the Mg content of bulk sample decreased to 11.7 wt%due to the element vaporization at high energy density,and the density of this additively manufactured Al Mg Si Sc Zr alloy was 2.538 g/cm^(3),which is4.2%8.5%lighter than that of other SLM-processed Al alloys.After heat-treated(HT)at 325℃and 6 h,the microstructure was almost unchanged with an alternate distribution of fine equiaxed crystals and coarse columnar crystals.Nano-sized Al3(Sc,Zr)and Mg_(2)Si phases precipitated dispersedly in the Al matrix,and the tensile strength increased from 487.6 MPa to 578.4 MPa for precipitation strengthening and fine grain strengthening.With a fine grain size of 2.53μm,an excellent corrosion resistance was obtained for the as-printed(AP)Al Mg Si Sc Zr alloy.While the corrosion resistance of HT sample decreased slightly for the formation of non-dense oxide layer and pitting corrosion induced by diffuse precipitation distribution.This SLM-printed Al Mg Si Sc Zr alloy with high specific strength,good thermal stability and excellent corrosion resistance has broad prospects for the aerospace and automotive applications. | Jiang Bi Zhenglong Lei Yanbin Chen Xi Chen Nannan Lu Ze Tian Xikun Qin | 2021 | Journal of Materials Science & Technology2021，，8： | 2 |
| 16 | An Investigation on the Molecular Characteristics and Intracellular Growth Ability among Environmental and Clinical Isolates of Legionella pneumophila in Sichuan Province, China显示文摘Objective To investigate the molecular characteristics and intracellular growth ability of Legionella pneumophila(L. pneumophila) strains from 1989 to 2016 in Sichuan Province, China. Methods Seventy-nine isolates of L. pneumophila were collected from environmental and clinical sources, including cooling towers, hot springs, bath water, fountains, and patients, and identified with 16 S rRNA gene analysis and serum agglutination assay. The isolates were then typed by Sequence-Based Typing(SBT), and Genotyping of forty-two LP1 strains were analyzed by means of multiple-locus VNTR analysis with 8 loci(MLVA-8). All strains were further analyzed for two virulence genes: Legionella vir homologue(lvh) and repeats in structural toxin(rtx A). The intracellular growth ability of 33 selected isolates was determined by examining their interaction with J774 cells. Results All isolates were identified to L. pneumophila including 11 serogroups, among which the main serogroup were LP1, accounting for 54.43%. Thirty-three different sequence types(STs) from five main clonal groups and five singletons were identified, along with 8 different MLVA patterns. Both the lvh and rtx A loci were found in all 79 strains. Thirty isolates showed high intracellular growth ability in J774 cells. Conclusion L. pneumophila is a potential threat to public health, and effective control and prevention strategies are urgently needed. | ZENG Lin Zi LIAO Hong Yu LUO Long Ze HE Shu Sen QIN Tian ZHOU Hai Jian LI Hong Xia CHEN Da Li CHEN Jian Ping | 2019 | Biomedical and Environmental Sciences2019，32，7： | 1 |
| 17 | Numerical Simulation of Dilute Phase Transportation in Pulse Riser显示文摘To study the hydrodynamic characteristics of gas-solid-phase flow in a pulse riser,a dense discrete particle model considering particle collisions and solid volume fraction is used.The core-annular flow in the enlarged-diameter section of the pulse riser is described,which can be destroyed with a high superficial gas velocity.The particle trajectory crossing effect and particle-particle and particle-wall collisions in the reduced-diameter section of the pulse riser can also destroy the core-annular flow and enhance the gas-solid interaction.The solid volume fraction exhibits an S-type distribution at different solid mass rates.The distribution of axial velocity,radial velocity,and relative slip velocity is investigated by analyzing the simulated results at different pulse riser diameter ratios.A suitable pulse riser diameter ratio can improve the performance of the pulse riser. | An Xiaoxi Yang Ze Qiao Yingyun Tian Yuanyu | 2021 | China Petroleum Processing & Petrochemical Technology2021，23，4： | 1 |
| 18 | Passivity-Based Robust Control Against Quantified False Data Injection Attacks in Cyber-Physical Systems显示文摘Secure control against cyber attacks becomes increasingly significant in cyber-physical systems(CPSs).False data injection attacks are a class of cyber attacks that aim to compromise CPS functions by injecting false data such as sensor measurements and control signals.For quantified false data injection attacks,this paper establishes an effective defense framework from the energy conversion perspective.Then,we design an energy controller to dynamically adjust the system energy changes caused by unknown attacks.The designed energy controller stabilizes the attacked CPSs and ensures the dynamic performance of the system by adjusting the amount of damping injection.Moreover,with the disturbance attenuation technique,the burden of control system design is simplified because there is no need to design an attack observer.In addition,this secure control method is simple to implement because it avoids complicated mathematical operations.The effectiveness of our control method is demonstrated through an industrial CPS that controls a permanent magnet synchronous motor. | Yue Zhao Ze Chen Chunjie Zhou Yu-Chu Tian Yuanqing Qin | 2021 | IEEE/CAA Journal of Automatica Sinica2021，8，8： | 1 |
| 19 | Syntheses, electrochemistry and crystal structure studies of novel cis -configuration biferrocene trinuclear complexes 显示文摘 | Duan Chun - ying Tian Yu - peng Liu Ze - hua | 1998 | Organoment Chem1998，570，： | 1 |
| 20 | Influencing factors of rat small intestinal epithelial cell cultivation and effects of radiation on cell proliferation显示文摘INTRODUCTIONCrypt epithelial cells in normal small intestineproliferate at a high speed. But they are verydifficult to culture in vitro and passage stably. A lotof studies have been done[1-16]. Some domestic labsisolated and cultured crypt cells from embryonalintestines and aseptic animal intestine, but failed.We introduced normal rat epithelial cell line-IEC-6from the USA and its living condition for stablepassage was successfully established after trials. Thecell line was testified to be the small intestinalepithelial cell by electron microscopy,immunihistochemistry and enzymatic histoch-emistry. It has been applied to some relatedresearch work[17-21]. It was found that manyfactors were involved in the culture system. Ourpresent study focuses on the culture method and theinfluencing factors on IEC-6. | Xin Ze Ran Yong Ping Su Yong Jiang Wei Guo Ping Ai Tian Min Cheng Yuan Lin Institute of Combined Injury, PLA, School of Preventive Medicine, Third Military Medical University. Chongqing 400038, China | 2001 | World Journal of Gastroenterology2001，7，1： | 1 |
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