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| 1 | Engineering Herbicide-Resistant Rice Plants through CRISPR/Cas9-Mediated Homologous Recombination of Acetolactate Synthase显示文摘 | Sun, Yongwei Zhang, Xin Wu, Chuanyin He, Yubing Ma, Youzhi Hou, Han Guo, Xiuping Du, Wenming Zhao, Yunde Xia, Lanqin | 2016 | Molecular Plant2016，9，4： | 94 |
| 2 | RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings显示文摘在有前列腺癌症的不同赛跑的病人之中有显著不同;然而,位于这差别下面的机制仍然保持不清楚。这里,我们在场 transcriptome 的一处全面风景用 RNA-seq,越过关于基因熔化的前列腺癌症 transcriptomes 的揭示巨大的差异,长 noncoding RNA (长 ncRNA ) ,其他的拼接和体的变化从中国人口 14 主要前列腺癌症和他们的配对的正常对应物介绍。14 个肿瘤(21.4%) 中的三个在中国病人怀有 TMPRSS2 尔格熔化,和这熔化的低流行进一步在一个另外的肿瘤集合(10/54=18.5%) 被证实。尤其是,二新奇基因熔化, CTAGE5-KHDRBS3 (20/54=37%) 和 USP9Y-TTTY15 (19/54=35.2%) ,在我们的耐心的队经常发生了。介绍的进一步系统的 transcriptional 识别了是在肿瘤表示的差别的众多的长 ncRNAs。在长 ncRNA 和基因的表示之间的关联的分析建议长 ncRNAs 可以在 transcriptional 规定以外有功能。这研究在中国人口产出新卓见进前列腺癌症的致病。 | Shancheng Ren Zhiyu Peng Jian-Hua Mao Yongwei Yu Changjun Yin Xin Gao Zilian Cui Jibin Zhang Kang Yi Weidong Xu Chao Chen Fubo Wang Xinwu Guo Ji Lu Jun Yang Min Wei Zhijian Tian Yinghui Guan Liang Tang Chuanliang Xu Linhui Wang Xu Gao Wei Tian Jian Wang Huanming Yang Jun Wang Yinghao Sun | 2012 | Cell Research2012，22，5： | 66 |
| 3 | Generation of Targeted Point Mutations in Rice by a Modified CRISPR/Cas9 System显示文摘 | Jingying Li Yongwei Sun Jinlu Du Yunde Zhao Lanqin Xia | 2017 | Molecular Plant2017，10，3： | 72 |
| 4 | Mapping wetland changes in China between 1978 and 2008显示文摘Four wetland maps for all China have been produced,based on Landsat and CBERS-02B remote sensing data between 1978 and 2008 (1978,1990,2000 and 2008).These maps were mainly developed by manual interpretation and validated by substantial field investigation in 2009.Based on these maps,we analyzed the 2008 wetland distribution in China and discussed wetland changes and their drivers over the past 30 years.(i) There were about 324097 km 2 of wetlands in 2008,for which inland marshes or swamps were the most common wetland type (35%),with lakes (26%) second.Most of the wetlands were in Heilongjiang,Inner Mongolia,Qinghai and Tibet,occupying about 55% of the national wetland area.(ii) From 1978 to 2008,China's wetland area continually and significantly decreased,by about 33% based on changes in the wetland map.This was in sharp contrast to the increase in artificial wetlands,which increased by about 122%.Inland marshes accounted for the main loss of total wetlands from 1978 to 2000.From 2000 through 2008,riverine and lacustrine wetlands constituted the main wetland loss.Fortunately however,the rate of wetland loss decreased from 5523 to 831 km 2 /a.(iii) The change ratio of lost natural wetlands (including inland and coastal wetlands) to non-wetlands has decreased slightly over the past 30 years.From 1978 to 1990,nearly all natural wetlands (98%) lost were transformed into non-wetlands.However,the ratio declined to 86% from 1990 to 2000,and to 77% from 2000 to 2008.(iv) All Chinese provinces were divided into three groups according to patterns of wetland changes,which could relate to the driving forces of such changes.Tibet was completely different from other provinces,as it was one representative example in which there was a net wetland increase,because of global warming and decreased human activity since 1990.Increased economic development caused considerable wetland loss in most eastern provinces,and artificial wetlands increased. | NIU ZhenGuo ZHANG HaiYing WANG XianWei YAO WenBo ZHOU DeMin ZHAO KuiYi ZHAO Hui LI NaNa HUANG HuaBing LI CongCong YANG Jun LIU CaiXia LIU Shuang WANG Lin LI Zhan YANG ZhenZhong QIAO Fei ZHENG YaoMin CHEN YanLei SHENG YongWei GAO XiaoHong ZHU WeiHong WANG WenQing WANG Hong WENG YongLing ZHUANG DaFang LIU JiYuan LUO ZhiCai CHENG Xiao GUO ZiQi GONG Peng | 2012 | Chinese Science Bulletin2012，57，22： | 51 |
| 5 | Nitrification performance of nitrifying bacteria immobilized in waterborne polyurethane at low ammonia nitrogen concentrations显示文摘Suspended and waterborne polyurethane immobilized nitrifying bacteria have been adopted for evaluating the effects of environmental changes,such as temperature,dissolved oxygen (DO) concentration and pH,on nitrification characteristics under conditions of low ammonia concentrations.The results showed that nitrification was prone to complete with increasing pH,DO and temperature.Sensitivity analysis demonstrated the effects of temperature and pH on nitrification feature of suspended bacteria were slightly greater than those of immobilized nitrifying bacteria.Immobilized cells could achieve complete nitrification at low ammonia concentrations when DO was sufficient.Continuous experiments were carried out to discuss the removal of ammonia nitrogen from synthetic micropollute source water with the ammonia concentration of about 1 mg/L using immobilized nitrifying bacteria pellets in an up-flow inner circulation reactor under different hydraulic retention times (HRT).The continuous removal rate remains above 80% even under HRT 30 min.The results verified that the waterborne polyurethane immobilized nitrifying bacteria pellets had great potential applications for micro-pollution source water treatment. | Yamei Dong Zhenjia Zhang Yongwei Jin Zhirong Li Jian Lu | 2011 | Journal of Environmental Sciences2011，23，3： | 32 |
| 6 | Incidence and mortality rate of esophageal cancer has decreased during past 40 years in Hebei Province,China显示文摘Background:Hebei province is located in North of China with of approximately 6% of whole national population.It is known as a high-risk area for esophageal cancer in China and worldwide.The aim of our study was to estimate the esophageal cancer burden and trend in Hebei Province.Methods:Eight cancer registries in Hebei Province submitted cancer registry data to the Hebei Provincial Cancer Registry Center.All data were qualified and compiled for cancer statistics in 2011.The pooled data were stratified by gender and age group(0,1-4,5-9,10-14…80+).Incidence and mortality rates were age-standardized to World Segi's population standard and expressed per 100,000 persons.In addition,proportions and cumulative incidence/mortality rates for esophageal cancer were calculated.Esophageal cancer mortality data during the periods 1973-1975,1990-1992,and 2004-2005 were extracted from the national death surveys.Mortality and incidence rate data from Cixian and Shexian were obtained from population-based cancer registries in each county.Results:The estimated number of newly diagnosed esophageal cancer cases and deaths in 2011 in Hebei Province was 24,318 and 18,226,respectively.The crude incidence rate of esophageal cancer was 33.37/100,000(males,42.18/100,000 and females,24.31/100,000).The age-standardized rate by world standard population(ASRW) was 28.09/100,000,ranking third among all cancers.The esophageal cancer mortality rate was 25.01/100,000(males,31.40/100,000 and females,18.45/100,000),ranking third in deaths among all cancers.The mortality rates of esophageal cancer displayed a significant decreasing trend in Hebei Province from 1973-1975(ASRW =48.69/100,000) to 2004-2005(ASRW =28.02/100,000),with a decreased rate of 42.45%.In Cixian,the incidence of esophageal cancer decreased from 250.76/100,000 to 106.74/100,000 in males and from 153.86/100,000 to 75.41/100,000 in females,with annual percentage changes(APC) of 2.13 and 2.16,while the mortality rates declined with an APC of 2.46 for males and 3.10 for females from 1988 to 2011.In Shexian,the incidence rate decreased from 116.90/100,000 to 74.12/100,000 in males and from 46.98/100,000 to 40.64/100,000 in females,while the mortality rates declined,with an APC of 4.89 in males from 2003 to 2011.Conclusions:Although the incidence and mortality rates of esophageal cancer remain high,an obvious decreasing trend has been observed in Hebei Province,as well as in high-risk regions,such as Cixian and Shexian,over the past 40 years. | Yutong He Yan Wu Guohui Song Yongwei Li Di Liang Jing Jin Denggui Wen Baoen Shan | 2015 | Chinese Journal of Cancer Research2015，27，6： | 22 |
| 7 | Differential regulation of survivin by p53 contributes to cell cycle dependent apoptosis显示文摘Recent studies indicate that cell-cycle checkpoints are tightly correlated with the regulation of apoptosis, in which p53 plays an important role. Our present works show that the expression of E6/E7 oncogenes of human papillomavirus in HeLa cells is inhibited in the presence of anti-tumor reagent tripchlorolide (TC), which results in the up-regulation of p53 in HeLa cells. Interestingly, under the same TC-treatment, the cells at the early S-phase are more susceptible to apoptosis than those at the middle S-phase although p53 protein is stabilized to the same level in both situations. Significant difference is exhibited between the two specified expression profiles. Further analysis demonstrates that anti-apoptotic gene survivin is up-regulated by p53 in the TC-treated middle-S cells, whereas it is down-regulated by p53 in the TC-treated early-S cells. Taken together, the present study indicates that the differential p53-regulated expres- sion of survivin at different stages of the cell cycle results in different cellular outputs under the same apoptosis-inducer. | YanJIN YongWEI LeiXIONG YingYANG JiaRuiWU | 2005 | Cell Research2005，15，5： | 21 |
| 8 | 羌塘高原湖水δ^(13)C_(DIC)值特征及影响因素分析显示文摘湖水溶解无机碳同位素(δ13CDIC)是研究湖泊碳循环的有效手段,其影响因素分析是古湖沼学中重建过去环境的理论基础,但国内关于这一方面的研究却还相对较少.本文研究了羌塘高原24个湖泊水体δ13CDIC值空间分布特征及其影响因素.结果表明,所选湖泊水体δ13CDIC值在-15.0‰至3.2‰之间,平均值为-1.2‰,表现出较高的同位素特征,部分湖泊δ13CDIC值甚至高于水体与大气CO2交换平衡时的同位素值.羌塘高原湖水普遍显碱性并具有较高的碱度,大部分咸水湖泊溶解CO2呈逸出状态,仅有少数淡水或微咸水湖泊以溶解大气CO2为主要特征.封闭湖泊水体DIC浓度和δ13CDIC值要明显高于入流河水,而外流湖泊与河水较为接近.湖水与大气CO2交换程度决定了羌塘高原封闭湖泊δ13CDIC值的高低.由于封闭湖泊DIC滞留时间长,湖水与大气CO2交换程度高,湖水δ13CDIC值比较接近平衡状态.本研究对认识羌塘高原封闭湖泊碳循环过程及沉积物中无机碳同位素环境意义具有重要理论价值. | 类延斌 姚檀栋 张恩楼 Sheng Yongwei 王伟财 李均力 王翔 | 2011 | 湖泊科学2011，23，5： | 16 |
| 9 | The impacts of climate change and human activities on grassland productivity in Qinghai Province, China显示文摘Qinghai 省,是三条主要的河的来源,,长江,黄河和 Lancang 河) 在东亚,在过去的十年经历了严重草地降级。这个工作的目的是在不同空间、时间的规模在草地生态系统上分析气候变化和人的活动的影响。为这个目的,回归和剩余分析从遥感数据和气象学的车站基于数据被使用。结果证明气候变化的效果在展出精力旺盛的植被生长的区域是大得多的。除了 Haixi 府,草地降级强烈在学习区域与气候因素被相关。在草地的质量的时间、空间的异质也被检测,它主要可能因为人的活动的效果。在 1980 年代,人的活动和草地植被生长在平衡,它意味着人的活动的影响处于有气候变化的平衡。在 1990 年代,连接到人的活动的重要草地降级不管多么被观察,首先在三河的 Headwaters 区域。自从 21 ^ ,啜 st ^ 世纪,这个不利趋势在金海·莱克区域并且在北省的边界附近继续,反面到在学习的东方部分被观察的。这些结果与一致当前在 Qinghai 省的草地降级的地位,它能用作本地草地管理和恢复节目的一个基础[出版摘要] | Fang YIN Xiangzheng DENG Qin JIN Yongwei YUAN Chunhong ZHAO | 2014 | Frontiers of Earth Science2014，8，1： | 16 |
| 10 | Nitrification characteristics of nitrobacteria immobilized in waterborne polyurethane in wastewater of corn-based ethanol fuel production显示文摘A technology to achieve stable and high ammonia nitrogen removal rates for corn distillery wastewater (ethanol fuel production) treatment has been designed.The characteristics of nitrifying bacteria entrapped in a waterborne polyurethane (WPU) gel carrier were evaluated after acclimation.In the acclimation period,nitrification rates of WPU-immobilized nitrobacteria were monitored and polymerase chain reaction (PCR) was also carried out to investigate the change in ammonium-oxidizing bacteria.The results showed that the pellet nitrification rates increased from 21 to 228 mg-N/(L-pellet·hr) and the quantity of the ammonia oxidation bacteria increased substantially during the acclimation.A continuous ammonia removal experiment with the anaerobic pond effluent of a distillery wastewater system was conducted with immobilized nitrifying bacteria for 30 days using an 80 L airlift reactor with pellets at a fill ratio of 15% (V/V).Under the conditions of 75 mg/L influent ammonia,hydraulic retention time (HRT) of 3.7-5.6 hr,and dissolved oxygen (DO) of 4 mg/L,the effluent ammonia concentration was lower than 10 mg/L and the ammonia removal efficiency was 90%.While the highest ammonia removal rate,162 mg-N/(L-pellet·hr),was observed when the HRT was 1.3 hr. | Yamei Dong Zhenjia Zhang Yongwei Jin Jian Lut Xuehang Cheng Jun Li Yan-yan Deng Ya-nan Feng Dongning Chen | 2012 | Journal of Environmental Sciences2012，24，6： | 14 |
| 11 | Preparation of ChlL-2 and IBDV VP2 Fusion Protein by Baculovirus Expression System显示文摘This study aims to produce an effective subunit vaccine against infectious bursal disease virus (IBDV). The genes of chicken interleukin-2 (ChIL-2) and IBDV viral protein 2 (VP2) were amplified and fused by splice overlap extension-polymerase chain reaction (SOE-PCR). The fusion gene was digested by EcoR I/Kpn I and inserted into pBacPAK8 vector, resulting in recombinant transfer plasmid pBacPakVP2-IL2. The recombinant plasmid was transfected into Sf-9 cells accompanied with hybrid nuclear polyhedrosis virus (HyNPV) genome DNA and lipofectin. Plaque-purification indicated that we had got the recombinant Hy-VP2-IL2. Fusion protein VP2-IL2was expressed effectively both in insect cells and bombyx mori. The expression of fusion protein was confirmed by ELISA, SDS-PAGE and Western blotting assay, respectively. This efficient system allows us to meet the need for inexpensive vaccines required by the poultry industry. | Yan Liu Yongwei Wei Xiaofeng Wu Lian Yu | 2005 | Cellular & Molecular Immunology2005，2，3： | 12 |
| 12 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 13 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 14 | Efficient allelic replacement in rice by gene editing: A case study of the NRT1.1B gene显示文摘Precise replacement of an existing allele in commercial cultivars with an elite allele is a major goal in crop breeding. A single nucleotide polymorphism in the NRT1.1 B gene between japonica and indica rice is responsible for the improved nitrogen use efficiency in indica rice. Herein, we precisely replaced the japonica NRT1.1 B allele with the indica allele, in just one generation, using CRISPR/Cas9 gene-editing technology.No additional selective pressure was needed to enrich the precise replacement events. This work demonstrates the feasibility of replacing any genes with elite alleles within one generation, greatly expanding our ability to improve agriculturally important traits. | Jingying Li Xin Zhang Yongwei Sun Jiahui Zhang Wenming Du Xiuping Guo Shaoya Li Yunde Zhao Lanqin Xia | 2018 | Journal of Integrative Plant Biology2018，60，7： | 11 |
| 15 | The High Energy X-ray telescope (HE) onboard the Insight-HXMT astronomy satellite显示文摘The Insight-Hard X-ray Modulation Telescope(Insight-HXMT) is a broadband X-ray and γ-ray(1-3000 ke V) astronomy satellite. One of its three main telescopes is the High Energy X-ray telescope(HE). The main detector plane of HE comprises 18 Na I(Tl)/Cs I(Na) phoswich detectors, where Na I(Tl) is used as the primary detector to measure ~ 20-250 ke V photons incident from the field of view(FOV) defined by collimators, and Cs I(Na) is used as the active shielding detector to Na I(Tl) by pulse shape discrimination. Additionally, Cs I(Na) is used as an omnidirectional γ-ray monitor. The HE collimators have a diverse FOV,i.e. 1.1°×5.7°(15 units), 5.7°×5.7°(2 units), and blocked(1 unit). Therefore, the combined FOV of HE is approximately5.7°×5.7°. Each HE detector has a diameter of 190 mm resulting in a total geometrical area of approximately 5100 cm2, and the energy resolution is ~15% at 60 ke V. For each recorded X-ray event by HE, the timing accuracy is less than 10 μs and the deadtime is less than 10 μs. HE is used for observing spectra and temporal variability of X-ray sources in the 20-250 ke V band either by pointing observations for known sources or scanning observations to unveil new sources. Additionally, HE is used for monitoring the γ-ray burst in 0.2-3 Me V band. This paper not only presents the design and performance of HE instruments but also reports results of the on-ground calibration experiments. | CongZhan Liu YiFei Zhang XuFang Li XueFeng Lu Zhi Chang ZhengWei Li AiMei Zhang YongJie Jin HuiMing Yu Zhao Zhang MinXue Fu YiBao Chen JianFeng Ji YuPeng Xu JingKang Deng RenCheng Shang GuoQing Liu FangJun Lu ShuangNan Zhang YongWei Dong TiPei Li Mei Wu YanGuo Li HuanYu Wang BoBing Wu YongJie Zhang Zhi Zhang ShaoLin Xiong Yuan Liu Shu Zhang HongWei Liu YiJung Yang Fan Zhang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 9 |
| 16 | Quaternary volcanism in the Nuomin River and Kuile River area of the Greater Hinggan Mountains显示文摘Field investigations have determined 24 Quaternary volcanoes and volcanic rocks with an area of about 600 km 2 in the Nuomin River and Kuile River area in the north of the Greater Hinggan Mountains.In the volcanic field,explosive eruption produced pyroclasts,which constitute volcanic cones,and effusive eruption produced aa,pahoehoe and block lava,which make up lava flows.There are three volcano types here,i.e.,cinder cone,spatter cone,and scutulum type volcano.Multi-vent pyroclastic cones and scutulum type volcanoes characterize this volcanic field.The volcanic features,stratigraphy,and weathering extent,in conjunction with dating data,indicate that the volcanism occurred in four periods:early Pleistocene,middle Pleistocene,late Pleistocene,and Holocene.Basalts of the early Pleistocene dominated by lava flows were distributed in a few valleys.Volcanic products of the middle Pleistocene constitute the main part of the Quaternary volcanic deposits,which indicates the peak season of volcanism.Volcanism in the late Pleistocene and Holocene were constrained in the Bila River valley,products of which make up fresh lava flows and spectacular volcanoes. | ZHAO YongWei FAN QiCheng BAI ZhiDa SUI JianLi | 2013 | Science China Earth Sciences2013，56，2： | 9 |
| 17 | Dynamic property tests of frozen red sandstone using a split hopkinson pressure bar显示文摘In this study, frozen red sandstone specimens were impacted by a Split Hopkinson bar (SHPB), with a velocity of 4.558 ~ 6.823 ms-1. The temperature of the specimens was maintained at -15℃ during the experiment. For comparison purposes, static uniaxial compression tests were conducted in advance using a freezing triaxial test machine. Four stress-strain curves were obtained in diff erent average strain rates. The test results suggested that when the average strain rate is low, the specimen strength changes gradually;but when it is high, its strength changes rapidly. When the average strain rate is 120.73 s-1, the peak value of stress is as high as 82.96 MPa, which is about two times that of the static compressive strength of 44.1 MPa. A constitutive model was established that was composed of the damaged, viscoelastic and spring bodies, and revealed the variations of compressive strength and strain for the frozen red sandstone under diff erent high strain rates. The test results also showed that the failure form was correlated to the average strain rate of the frozen red sandstone. When the average strain rate is low, the damage was only distributed on the specimen’s edges. However, as the average strain rate increases, the damage range extended to the central parts of the specimen. When the average strain rate reached 107.34s-1, the specimen was smashed. | Shan Renliang Song Yongwei Song Liwei Bai Yao | 2019 | Earthquake Engineering and Engineering Vibration2019，18，3： | 8 |
| 18 | Expression,Characterization and Immunogenicity of a Major Outer Membrane Protein from Vibrio alginolyticus显示文摘Vibrio alginolyticus 是对人和海洋的动物普通的 Vibrio 病原体之一。在主人免疫者反应的感染和正式就职期间,细菌玩的外部膜蛋白质一个重要角色。在这研究,外部膜蛋白质基因(ompW ) 从 V 被克隆。alginolyticus 并且在 Escherichia 关口 i 表示了。645 bp 开的读框架(ORF ) 与 23.3 kDa 的预言的分子的重量编码 214 氨基酸残余的蛋白质。氨基酸顺序与 Photobacterium damselae (96.2%) 和 Vibrioparahaemolyticus (94.4%) 的显示出高身份。排列分析显示 OmpW 高度被保存。Sodiumdodecyl sulfate-polyacrylamide 凝胶电泳证明基因在 E.coli BL21 (DE3 ) 是过去表示的。蛋白质印迹分析表明表示蛋白质有免疫反应。Therecombinant 蛋白质被亲和层析在 Ni-NTA Superflow 树脂上净化。大黄 croaker 种牛痘,净化的 OmpW 显著地出现了增加了抗体到 OmpW,它能由 V 抵抗感染。alginolyticus。特定的抗体被 enzyme-linkedimmunosorbent 试金检测。这研究建议保存 OmpW 能是对由 V 的感染的一个有效疫苗的候选人。alginolyticus。 | Ronghua QIAN Wuying CHU Zhijuan MAO Chongwen ZHANG Yongwei WEI Lian YU | 2007 | Acta Biochimica et Biophysica Sinica2007，39，3： | 8 |
| 19 | An improved OFDM chirp waveform used for MIMO SAR system显示文摘Special attention has been devoted to multi-input multi-output(MIMO)synthetic aperture radar(SAR)systems in recent years.The applications of MIMO SAR systems which involve 3D imaging,highresolution wide-swath remote sensing,and multi-baseline interferometry are seriously limited to the orthogonal waveforms.Although orthogonal frequency division multiplexing(OFDM)chirp waveforms can be used for MIMO SAR systems to avoid intra-pulse interferences,there is a small frequency shift between the transmitted OFDM pulses.This vulnerable shift,which can not only affect the waveform orthogonality,but also introduce residual phase error,renders the OFDM waveforms impractical.In this paper,an improved OFDM chirp waveform which works without the mentioned shift is presented,along with the novel modulation and efficient demodulation procedures.Comparison between the improved and the conventional OFDM chirp waveforms is detailed.The influence of random noise,quantization error,and Doppler shift on the orthogonality of OFDM waveform is also investigated in this paper.Theoretical analysis and simulation results illustrate the feasibility of this waveform scheme. | WANG Jie LIANG XingDong DING ChiBiao CHEN LongYong ZHOU LiangJiang DONG YongWei | 2014 | Science China(Information Sciences)2014，57，6： | 6 |
| 20 | SVOM gamma ray monitor显示文摘The space-based multi-band astronomical Variable Object Monitor(SVOM) mission is dedicated to the detection,localization and broad-band study of gamma-ray bursts(GRBs) and other high-energy transient phenomena.The gamma ray monitor(GRM) onboard is designed to observe GRBs up to 5 MeV.With this instrument,one of the key GRB parameters,Epeak,can be easily measured in the hard X-ray band.It can achieve a detection rate of 100 GRBs per year which ensures the scientific output of SVOM. | DONG YongWei,WU BoBing,LI YanGuo,ZHANG YongJie & ZHANG ShuangNan Key Laboratory of Particle Astrophysics,Institute of High Energy Physics,Chinese Academy of Sciences,Beijing 100049,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，S1： | 5 |
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