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| 1 | The Reference Genome of Tea Plant and Resequencing of 81 Diverse Accessions Provide Insights into Its Genome Evolution and Adaptation显示文摘Tea plant is an important economic crop,which is used to produce the world's oldest and most widely consumed tea beverages.Here,we present a high-quality reference genome assembly of the tea plant(Camellia sinensis var.sinensis)consisting of 15 pseudo-chromosomes.LTR retrotransposons(LTR-RTs)account for 70.38%of the genome,and we present evidence that LTR-RTS play critical roles in genome size expansion and the transcriptional diversification of tea plant genes through preferential insertion in promoter regions and introns.Genes,particularly those coding for terpene biosynthesis pro-teins,associated with tea aroma and stress resistance were significantly amplified through recent tandem duplications and exist as gene clusters in tea plant genome.Phylogenetic analysis of the sequences of 81 tea plant accessions with diverse origins revealed three well-differentiated tea plant populations,support-ing the proposition for the southwest origin of the Chinese cultivated tea plant and its later spread to western Asia through introduction.Domestication and modern breeding left significant signatures on hundreds of genes in the tea plant genome,particularly those associated with tea quality and stress resis-tance.The genomic sequences of the reported reference and resequenced tea plant accessions provide valuable resources for future functional genomics study and molecular breeding of improved cul-tivars of tea plants. | Enhua Xia Wei Tong Yan Hou Yanlin An Linbo Chen Qiong Wu Yunlong Liu Jie Yu Fangdong Li Ruopei Li Penghui Li Huijuan Zhao Ruoheng Ge Jin Huang Ali Inayat Mallano Yanrui Zhang Shengrui Liu Weiwei Deng Chuankui Song Zhaoliang Zhang Jian Zhao Shu Wei Zhengzhu Zhang Tao Xia Chaoling Wei Xiaochun Wan | 2020 | Molecular Plant2020，13，7： | 51 |
| 2 | High-performance modified uni-traveling carrier photodiode integrated on a thin-film lithium niobate platform显示文摘Lithium niobate on insulator(LNOI)has become an intriguing platform for integrated photonics for applications in communications,microwave photonics,and computing.Whereas,integrated devices including modulators,resonators,and lasers with high performance have been recently realized on the LNOI platform,high-speed photodetectors,an essential building block in photonic integrated circuits,have not been demonstrated on LNOI yet.Here,we demonstrate for the first time,heterogeneously integrated modified uni-traveling carrier photodiodes on LNOI with a record-high bandwidth of 80 GHz and a responsivity of 0.6 A/W at a 1550-nm wavelength.The photodiodes are based on an n-down In GaAs/InP epitaxial layer structure that was optimized for high carrier transit time-limited bandwidth.Photodiode integration was achieved using a scalable wafer die bonding approach that is fully compatible with the LNOI platform. | XIANGWEN GUO LINBO SHAO LINGYAN HE KEVIN LUKE JESSE MORGAN KEYE SUN JUNYI GAO TA-CHING TZU YANG SHEN DEKANG CHEN BINGTIAN GUO FENGXIN YU QIANHUAN YU MASOUD JAFARI MARKO LONčAR MIAN ZHANG ANDREAS BELING | 2022 | Photonics Research2022，10，6： | 2 |
| 3 | Increasing Momentum-Like Factors:A Method for Reducing Training Errors on Multiple GPUs显示文摘In distributed training,increasing batch size can improve parallelism,but it can also bring many difficulties to the training process and cause training errors.In this work,we investigate the occurrence of training errors in theory and train ResNet-50 on CIFAR-10 by using Stochastic Gradient Descent(SGD) and Adaptive moment estimation(Adam) while keeping the total batch size in the parameter server constant and lowering the batch size on each Graphics Processing Unit(GPU).A new method that considers momentum to eliminate training errors in distributed training is proposed.We define a Momentum-like Factor(MF) to represent the influence of former gradients on parameter updates in each iteration.Then,we modify the MF values and conduct experiments to explore how different MF values influence the training performance based on SGD,Adam,and Nesterov accelerated gradient.Experimental results reveal that increasing MFs is a reliable method for reducing training errors in distributed training.The analysis of convergent conditions in distributed training with consideration of a large batch size and multiple GPUs is presented in this paper. | Yu Tang Zhigang Kan Lujia Yin Zhiquan Lai Zhaoning Zhang Linbo Qiao Dongsheng Li | 2022 | Tsinghua Science and Technology2022，27，1： | 1 |
| 4 | Toxic effects ofcitrinin on the male reproductive system in mice显示文摘 | HAN Qingqing YU Linbo GUO Yunqian | 2012 | Experimental andToxicologic Pathology2012，64，： | 1 |
| 5 | Optimization of a single-drop microextraction procedure for the determination of organophosphorus pesticides in water and fruit juice with gas chromatography-flame photometric detection显示文摘 | Qin Xiao Bin Hu Chunhe Yu Linbo Xia Zucheng Jiang | 2005 | Talanta2005，，4： | 1 |
| 6 | Toxic effects of citrinin on the male reproductive system in mice显示文摘 | Han Qingqing Yu Linbo Guo Yunqian Liu Shuqiang | 2010 | Experimental and Toxicologic Pathology2010，，： | 1 |
| 7 | CDP-GAN:Near-Infrared and Visible Image Fusion Via Color Distribution Preserved GAN显示文摘Dear Editor,This letter is concerned with dealing with the great discrepancy between near-infrared(NIR)and visible(VS)image fusion via color distribution preserved generative adversarial network(CDP-GAN).Different from the global discriminator in prior GAN,conflict of preserving NIR details and VS color is resolved by introducing an attention guidance mechanism into the discriminator.Moreover。 | Jun Chen Kangle Wu Yang Yu Linbo Luo | 2022 | IEEE/CAA Journal of Automatica Sinica2022，9，9： | 1 |
| 8 | Cluster Randomization Trial of Sequence Mass Screening for Colorectal Cancer显示文摘 | Shu Zheng M.D. Kun Chen M.D. Xiyong Liu M.D. Xinyuan Ma M.D. Hai Yu Ph.D. Kang Chen Kaiyan Yao Lun Zhou M.D. Linbo Wang M.D. Peiling Qiu M.D. Yongchuan Deng M.D. Suzhan Zhang M.D | 2003 | Diseases of the Colon & Rectum2003，，1： | 1 |
| 9 | Temporal dynamic changes of connexin 43 expression in C6 cells following lipopolysaccharide stimulation显示文摘Connexin 43,a gap junction protein,is expressed mainly in glia in the central nervous system.Neuroinflammation plays an important role in central nervous system injury.Changes to glial connexin 43 levels and neuroinflammation may trigger brain injury and neurodegenerative diseases.To illustrate the relationship between connexin 43 and neuroinflammation,this study investigated how connexin 43 expression levels change in lipopolysaccharide-stimulated rat C6 glioma cells.C6 cells were treated with 0.05,0.25,0.5,1,2.5 and 5 μg/mL lipopolysaccharide for 24 hours.The nitrite estimation-detected nitric oxide release level was elevated substantially after lipopolysaccharide stimulation.To test the transcriptional level changes of inducible nitric oxide synthase,tumor necrosis factor-α and connexin 43 mRNA,C6 cells were treated with 5 μg/mL lipopolysaccharide for 3-48 hours.Reverse transcription-PCR showed that the expression of inducible nitric oxide synthase and tumor necrosis factor-α mRNA increased over time,but connexin 43 mRNA levels increased in lipopolysaccharide-stimulated C6 cells at 3 and 6 hours,and then decreased from 12 to 48 hours.Connexin 43 protein expression was detected by immunofluorescence staining,and the protein levels matched the mRNA expression levels.These results suggest that connexin 43 expression is biphasic in lipopolysaccharide-induced neuroinflammation in C6 cells,which may be correlated with the connexin 43 compensatory mechanism. | Ling Liu Zhenping Gao Linbo Zhang Lue Su Guojun Dong Haiyang Yu Jiayi Tian Hang Zhao Yanyan Xu Haiyan Liu | 2012 | Neural Regeneration Research2012，7，25： | 1 |
| 10 | Spectral control of nonclassical light pulses using an integrated thin-film lithium niobate modulator显示文摘Manipulating the frequency and bandwidth of nonclassical light is essential for implementing frequency-encoded/multiplexed quantum computation,communication,and networking protocols,and for bridging spectral mismatch among various quantum systems.However,quantum spectral control requires a strong nonlinearity mediated by light,microwave,or acoustics,which is challenging to realize with high efficiency,low noise,and on an integrated chip.Here,we demonstrate both frequency shifting and bandwidth compression of heralded single-photon pulses using an integrated thin-film lithium niobate(TFLN)phase modulator.We achieve record-high electro-optic frequency shearing of telecom single photons over terahertz range(±641 GHz or±5.2 nm),enabling high visibility quantum interference between frequency-nondegenerate photon pairs.We further operate the modulator as a time lens and demonstrate over eighteen-fold(6.55 nm to 0.35 nm)bandwidth compression of single photons.Our results showcase the viability and promise of on-chip quantum spectral control for scalable photonic quantum information processing. | Di Zhu Changchen Chen Mengjie Yu Linbo Shao Yaowen Hu CJXin Matthew Yeh Soumya Ghosh Lingyan He Christian Reimer Neil Sinclair Franco N.C.Wong Mian Zhang Marko Loncar | 2022 | Light(Science & Applications)2022，11，12： | 0 |
| 11 | Investigation and mitigation of Mott neuronal oscillation fluctuation in spiking neural network显示文摘Mott devices,featuring low hardware cost and high energy efficiency,have been demonstrated as a key oscillatory element in artificial neurons to enable spiking neural networks(SNNs)such as conversionbased SNNs(CSNNs).However,there will be inevitably non-ideal fluctuation in the oscillation behavior,causing the accuracy degradation of networks.In this paper,we investigate the Mott neuronal oscillation fluctuation(NOF)through experiments and modeling.The results show that the NOF phenomenon conforms to Gaussian distribution and originates from thermal fluctuation induced switching voltage variations.We construct a two-layer CSNN for image recognition tasks to study the NOF effect and propose the activation function boundary(AFB)method to strengthen the stability of the network.The results indicate that AFB can improve the accuracy of CSNN by up to 15.5%by tightening output distribution. | Lindong WU Zongwei WANG Lin BAO Linbo SHAN Zhizhen YU Yunfan YANG Shuangjie ZHANG Guandong BAI Cuimei WANG John ROBERTSON Yuan WANG Yimao CAI Ru HUANG | 2024 | Science China(Information Sciences)2024，67，2： | 0 |
| 12 | Bio-inspired Attachment Mechanism of Dynastes Hercules:Vertical Climbing for On-Orbit Assembly Legged Robots显示文摘With the increasing size of space facilities,on-orbit assembly requires robots to move on different heights of trusses.This paper proposes a bio-inspired attachment mechanism for robot feet to enable climbing on different heights of trusses.Inspired by the attachment and grasping abilities of Dynastes Hercules,we utilize its foot microstructures,such as microhooks and setae,to achieve efficient contact and firm grip with the surface.The morphology and arrangement of these structures can inspire the design of robot feet to improve their grasping and stability performance.We study the biological structure of Dynastes Hercules,design and optimize the bio-inspired structure,analyze the influence of various factors from theoretical and experimental perspectives,and verify the feasibility of the scheme through simulation.We propose an ideal climbing strategy that provides useful reference for robot applications in practice.Moreover,the influence laws of various factors in this paper can be applied to robot foot design to improve their operation ability and stability performance in the space environment.This bio-inspired mechanism can improve robot working range and efficiency,which is critical for on-orbit assemblyin space. | Yuetian Shi Xuyan Hou Zhonglai Na Jie Zhou Nan Yu Song Liu Linbo Xin Guowei Gao Yuhui Liu | 2024 | Journal of Bionic Engineering2024，21，1： | 0 |
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