|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Slope Stability Analysis Based on Group Decision Theory and Fuzzy Comprehensive Evaluation显示文摘A slope stability evaluation method is proposed combining group decision theory,the analytic hierarchy process and fuzzy comprehensive evaluation.The index weight assignment of each evaluation element is determined by group decision theory and the analytic hierarchy process,and the membership degree of each indicator is determined based on fuzzy set theory.According to the weights and memberships,the membership degrees of the criterion layer are obtained by fuzzy operations to evaluate the slope stability.The results show that(1)the evaluation method comprehensively combines the effects of multiple factors on the slope stability,and the evaluation results are accurate;(2)the evaluation method can fully leverage the experience of the expert group and effectively avoid evaluation errors caused by the subjective bias of a single expert;(3)based on a group decision theory entropy model,this evaluation method can quantitatively evaluate the reliability of expert decisions and effectively improve the efficiency of expert group discussion;and(4)the evaluation method can transform the originally fuzzy and subjective slope stability evaluation into a quantitative evaluation. | Peng Xia Xinli Hu Shuangshuang Wu Chunye Ying Chang Liu | 2020 | Journal of Earth Science2020，31，6： | 11 |
| 2 | Linear Strain-Gradient Effect on the Energy Bandgap in Bent CdS Nanowires显示文摘尽管在半导体的可能的非同类的紧张效果被调查了因为在一半上世纪和紧张坡度能每在灵活 nanostructures 的测微计是超过 1% ,我们仍然缺乏他们对精力乐队的影响的理解。这里,我们进行紧张坡度的系统的阴极射线发光光谱学研究在在低温度的有弹性地弄弯的 CdS nanowires 的导致的激子精力移动,并且发现在弄弯的 nanowires 的激子精力红移动与紧张坡度成正比,格子失真的一个索引。密度功能的计算在弄弯的 nanostructures 显示出乐队差距减小的一样的趋势并且揭示内在的机制。半导体的乐队差距上的重要线性紧张坡度效果应该在在 nanoelectronics 调节光电子的性质的方法上打开新灯。 | Qiang Fu Zi Yue Zhang Liangzhi KOU Peicai Wu Xiaobing Han Xinli Zhu Jingyun Gao Jun Xu Qing Zhao Wanlin Guo Dapeng Yu | 2011 | Nano Research2011，4，3： | 5 |
| 3 | A MyD88-JAK1-STAT1 complex directly induces SOCS-1 expression in macrophages infected with Group A Streptococcus显示文摘一些病原体能使用表明 1 的 cytokine (SOCS-1 ) 的主人 suppressor,一个重要否定反馈的分子,有免疫力的避免的主要模式。这里,我们发现那个组 A 链球菌(气体) 能够在 RAW264.7 和 BMDM 巨噬细胞导致 SOCS-1 表示。IFN-β在由气体跟随 cytokine 表示的正式就职的巨噬细胞在导致气体的 SOCS-1 表示起一个作用,代表 SOCS-1 表示的古典小径。然而,当感染气体的房间与 anti-IFN-β 被孵化时,气体也导致了 STAT1 激活和 SOCS-1 表示;在这研究的 monoclonal 抗体。而且,在把 TLR4 −/− BMDM 巨噬细胞与作比较之上野类型(WT ) 房间,我们发现 TLR4 也在 SOCS-1 的正式就职起一个必要作用。MyD88,是为 TLR4 的适配器蛋白质,由与 Janus kinase 形成建筑群贡献 STAT1 激活和 phosphorylation 1 (JAK1 ) 并且信号变换器和在巨噬细胞的抄写 1 的使活跃之物(STAT1 ) 。而 JAK1 的表示是未受影响的, STAT1 的刺激气体的表示严重地在 MyD88 −/− 巨噬细胞被损害,建议 MyD88 涉及 STAT1 表示和 phosphorylation。一起,这些数据除了 IFN-β 表明了那;发信号并且 MyD88 复杂形成, JAK1 和 STAT1 在一条新奇小径行动直接在感染气体的巨噬细胞导致 SOCS-1 表示,它可能对快速的细菌的感染更导致。 | Jinghua Wu Cuiqing Ma Haixin Wang Shuhui Wu Gao Xue Xinli Shi Zhang Song Lin Wei | 2015 | Cellular & Molecular Immunology2015，12，3： | 5 |
| 4 | Tangnaikang improves insulin resistance and β-cell apoptosis by ameliorating metabolic inflammation in SHR.Cg-Lepr^(cp)/NDmcr rats显示文摘OBJECTIVE: To investigate the effects of Tangnaikang(TNK), a mixture of five herbal plant extracts,on inflammation-mediated insulin resistance andβ-cell apoptosis in SHR.Cg-Leprcp/NDmcr(SHR-cp)rats.METHODS: Seven-week-old SHR-cp rats were randomly divided into a control(CON) group and a TNK(3.24 g/kg) group. Wistar-Kyoto rats at the same age were used as the normal control group.After 7 weeks of continuous intragastric administration of TNK, the glucose metabolic status and insulin sensitivity of the rats were evaluated by assessing fasting serum glucose(FBG), the oral glucose tolerance test(OGTT), fasting serum insulin(FINS),and the insulin sensitivity index(ISI). Serum tumor necrosis factor-α(TNF-α), interleukin-6(IL-6), C-reactive protein(CRP) and adiponectin were measured via enzyme-linked immunosorbent assays.Macrophage infiltration and apoptosis in adipose tissues were detected through F4/80 immunohistochemistry and the terminal deoxynucleotidyl transferase d UTP nick end labeling(TUNEL) assay. Islet morphology and β-cell apoptosis were investigated using double immunofluorescence staining and the TUNEL assay. The expression of cytokine genes in adipose tissue, the liver, and the pancreas was detected in real-time polymerase chain reaction assays. The expression and phosphorylation levels of insulin signaling-, inflammation-, and β-cell survival-related proteins in the liver and pancreas of SHR-cp rats were detected by western blotting.RESULTS: TNK(3.24 g/kg) treatment significantly decreased body weight, FBG and FINS; improved impaired glucose tolerance; increased the ISI; reduced serum levels of TNF-α, CRP and IL-6; and increased serum adiponectin. The m RNA expression of inflammatory markers was markedly reduced in the liver, pancreas, and adipose tissue. F4/80-and TUNEL-positive cells in adipose tissues were decreased, as was the number of TUNEL-positiveβ-cells. The phosphorylation of c-Jun N-terminal kinase and that of insulin receptor substrate-1 at serines 307 and 1101 was significantly decreased.In the pancreas, the expression of nuclear factor kappa-light chain-enhancer of activated B cells-p65 was significantly decreased, and phosphoinositide3-kinase and IRS-2 were significantly increased.CONCLUSION: TNK was able to improve insulin resistance and β-cell apoptosis in SHR-cp rats, which might be associated with its ability to relieve the overall and local metabolic inflammatory responses observed in SHR-cp rats. | Li Linyi Hisae Yoshitomi Qin Lingling Wu Xinli Zhou Tian Wang Haiyan Jiang Yueying Wei Ying Xu Tunhai Liu Tonghua Gao Ming | 2017 | Journal of Traditional Chinese Medicine2017，37，3： | 3 |
| 5 | A full-process intelligent trial system for smart court显示文摘In constructing a smart court,to provide intelligent assistance for achieving more efficient,fair,and explainable trial proceedings,we propose a full-process intelligent trial system(FITS).In the proposed FITS,we introduce essential tasks for constructing a smart court,including information extraction,evidence classification,question generation,dialogue summarization,judgment prediction,and judgment document generation.Specifically,the preliminary work involves extracting elements from legal texts to assist the judge in identifying the gist of the case efficiently.With the extracted attributes,we can justify each piece of evidence’s validity by establishing its consistency across all evidence.During the trial process,we design an automatic questioning robot to assist the judge in presiding over the trial.It consists of a finite state machine representing procedural questioning and a deep learning model for generating factual questions by encoding the context of utterance in a court debate.Furthermore,FITS summarizes the controversy focuses that arise from a court debate in real time,constructed under a multi-task learning framework,and generates a summarized trial transcript in the dialogue inspectional summarization(DIS)module.To support the judge in making a decision,we adopt first-order logic to express legal knowledge and embed it in deep neural networks(DNNs)to predict judgments.Finally,we propose an attentional and counterfactual natural language generation(AC-NLG)to generate the court’s judgment. | Bin WEI Kun KUANG Changlong SUN Jun FENG Yating ZHANG Xinli ZHU Jianghong ZHOU Yinsheng ZHAI Fei WU | 2022 | Frontiers of Information Technology & Electronic Engineering2022，23，2： | 2 |
| 6 | Forest biomass is strongly shaped by forest height across boreal to tropical forests in China显示文摘Forest height is a major factor shaping geographic biomass patterns,and there is a growing dependence on forest height derived from satellite light detecting and ranging(LiDAR)to monitor large-scale biomass patterns.However,how the relationship between forest biomass and height is modulated by climate and biotic factors has seldom been quantified at broad scales and across various forest biomes,which may be crucial for improving broad-scale biomass estimations based on satellite LiDAR.Methods We used 1263 plots,from boreal to tropical forest biomes across China,to examine the effects of climatic(energy and water avail-ability)and biotic factors(forest biome,leaf form and leaf phenol-ogy)on biomass-height relationship,and to develop the models to estimate biomass from forest height in China.Important Findings(i)Forest height alone explained 62%of variation in forest biomass across China and was far more powerful than climate and other biotic factors.(ii)However,the relationship between biomass and forest height were significantly affected by climate,forest biome,leaf phenology(evergreen vs.deciduous)and leaf form(needleleaf vs.broadleaf).among which,the effect of climate was stronger than other factors.The intercept of biomass-height relationship was more affected by precipitation while the slope more affected by energy availability.(iii)When the effects of climate and biotic factors were considered in the models,geographic biomass patterns could be well predicted from forest height with an r2 between 0.63 and 0.78(for each forest biome and for all biomes together).For most biomes,forest biomass could be well predicted with simple models includ-ing only forest height and climate.(iv)We provided the first broad-scale models to estimate biomass from forest height across China,which can be utilized by future LiDAR studies.(v)our results suggest that the effect of climate and biotic factors should be carefully considered in models estimating broad-scale forest biomass patterns with satellite LiDAR. | Xian Wu Xiangping Wang Yulian Wu Xinli Xia Jingyun Fang | 2015 | Journal of Plant Ecology2015，8，6： | 2 |
| 7 | Positioning taxonomic research for the future显示文摘Why do taxonomists matter? The work of taxonomists is often understated if not completely misunderstood. Without taxonomists, organisms cannot be accurately identified, neither can these organisms be given universally accepted names, and reliably positioned in the phylogenetic tree of life. Thanks to the work of taxonomists over the last 269 years since Carl Linnaeus established the binomial system, we can now measure the health and wealth of our biodiversity in a refined, science-based inventory prescribed by stringent nomenclatural rules. | Deyuan Hong Wenying Zhuang Min Zhu Keping Ma Xiaoquan Wang Dawei Huang Yalin Zhang Guodong Ren Wenjun Bu Wanzhi Cai Dong Ren Ding Yang Aiping Liang Fengyan Bai Runzhi Zhang Fumin Lei Shuqiang Li Hongzhi Kong Lei Cai Yucheng Dai Chaodong Zhu Qisen Yang Jun Chen Zhongli Sha Jianping Jiang Jing Che Donghui Wu Jiatang Li Qiang Wang Xinli Wei Ming Bai Xingyue Liu Xuexin Chen Gexia Qiao | 2022 | Zoological Systematics2022，47，3： | 2 |
| 8 | A fusion–fission hybrid reactor with water-cooled pressure tube blanket for energy production显示文摘 | Hongchun Wu Tiejun Zu Suizheng Qiu Xinli Gao Youqi Zheng Liangzhi Cao Wenxi Tian | 2012 | Progress in Nuclear Energy2012，，： | 1 |
| 9 | Study on supplier selection model for supply chain collaboration显示文摘 | XU Xing LI Renwang WU Xinli | 2011 | Advances in Intelli gent and Soft Computing2011，123，24： | 1 |
| 10 | High-cycle fatigue behavior of Mg-8Li-3Al-2Zn-0.5Y alloy under different states显示文摘In this study,the tensile and high-cycle fatigue properties of as-cast,solid solution treated and as-extruded Mg-8Li-3Al-2Zn-0.5Y alloy are investigated.The results show that the yield strength and ultimate tensile strength of as-cast alloy is 198.1 MPa and 222.5 MPa,which are improved to 274.7 MPa and 321.7 MPa,282.4 MPa and 319.3 MPa after solid solution and extrusion treatment,respectively.The high-cycle fatigue strength(at 10^(7)cycles,R=-1)of as-cast studied alloy is 65 MPa,which is improved to 90 MPa and 105 MPa after solid solution and extrusion treatment,respectively.The improvement of fatigue property of the solid solution treated alloy is mainly due to the lattice distortion caused by solid solution hindering the crack propagation.However,the improvement of fatigue property of the as-extruded alloy is mainly due to that the refined grains,stacked dislocations and dispersed secondary particles impede the crack propagation. | Xiang Peng Xinli Liang Wencai Liu Guohua Wu Hao Ji Xin Tong Liang Zhang Wenjiang Ding | 2021 | Journal of Magnesium and Alloys2021，9，5： | 1 |
| 11 | Influence of water pipe cooling on thermal stresses in mass concrete显示文摘 | Bai Xinli Wu Zeyu Ma Wenliang | | 0，，： | 1 |
| 12 | Feasibility and safety of combined interventional procedures in elderly patients with complex cardiovascular diseases:experience of a single medical center显示文摘Objectives:To report the clinical experience of combined interventional procedures in the treatment of elderly patients with coexisting two or more cardiovascular diseases in our medical center, and to assess the feasibility, safety and therapeutic efficacy of this management strategy. Methods : Patients were selected to the study if: 1) age >65 years; 2) with coexistence of two or more cardiovascular diseases which are indications for interventional therapy; 3) patients' general condition and organ functions allow the performance of combined multiple procedures; 4) the predicted procedure time is within 150 min; 5) the predicted contrast medium dosage is within 300 ml. The criteria we analyzed included procedural type, rocedural time, fluoroscopy time, dosage of contrast medium, success rates of the procedures, complications and in-hospital mortality. All patients were followed up for 30.4 ± 9.3 months,to determine the all-cause mortality, recurrence rates and adverse cardiac events. Results : From January 2000 to December 2004,combined interventional procedures were performed on 136 patients, with 2 procedures on 134 patients and 3 procedures on 2 patients.The mean procedure time was 115.4±11.6 min, the mean fluoroscopy time was 35.7±9.3 min, and the mean dosage of contrast medium used was 183.6±19.4 ml. Procedural success rate was 100%, no procedure related death or major complications occurred.Conclusion: Performed by a competent team, combined interventional procedures in elderly patients with multiple cardiovascular diseases were feasible and relatively safe. | Caiyi LU Shiwen WANG Xinli WU Qiao XUE Taohong HU Muyang YAN Rui CHEN Zhongren ZHAO Haiyun WU | 2005 | Journal of Geriatric Cardiology2005，2，3： | 1 |
| 13 | Long-term effect of stenting in unprotected left main coronary artery disease in the elderly显示文摘To evaluate the feasibility, safety and efficacy of percutaneous stent implantation for treating left main coronary artery (LMCA) stenosis. Methods Consecutive patients with unprotected left main coronary artery disease treated by stent-based percutaneous intervention (PCI) at 6 medical centers in China were enrolled. Procedural data and clinical outcomes were obtained from all patients. Results From January 2001 to December 2004, 138 patients (79 males and 59 females; mean age: 69.7±5.8 years)underwent PCI for LMCA stenosis. Bare metal stents (BMS) were implanted in 51 patients with non-bifurcational lesions and in 5 patients with bifurcational lesions from January of 2001 to June of 2003 (BMS group);. Drug eluting stents (DES) were used unselectively to cover both bifurcational and non-bifurcational lesions in 86 patients from July of 2003 to December of 2004 (DES group). Procedural success rate of the 138 cases was 98% (135/138). One patient (0.7%) with bifurcation lesion who was treated with DES died from severe heart failure 2 weeks after the procedure. During a mean follow up period of 21.3 ± 5.6 months, one patient died from renal failure, one from sudden cardiac death, 4 underwent target lesion revascularization (TLR) in the BMS group, which all occurred in patients with bifurcational lesions; whereas in the DES group no deaths occurred and only one patient with bifurcational lesion had TLR. Conclusions (1) PCI is feasible and relatively safe to treat unprotected left main coronary artery disease in elderly patients at medical centers with experienced professionals. (2) BMS and DES have similar immediate and long-term efficacy in the treatment of ostium and shaft lesions of the LMCA. (3) DES are strongly suggested in the therapy of distal bifurcation lesion of unprotected LMCA. | Caiyi LU Shiwen WANG Lingling LIU Qiao XUE Xinli WU Taohong HU Pingshuan DONG Zhiping WANG Shenfang TIAN Pinfa LIU Jicai ZANG | 2005 | Journal of Geriatric Cardiology2005，2，4： | 1 |
| 14 | Effects of seasonal climatic variability on several toxic contaminants in urban lakes: Implications for the impacts of climate change显示文摘Climate change is supposed to have influences on water quality and ecosystem.However,only few studies have assessed the effect of climate change on environmental toxic contaminants in urban lakes.In this research,response of several toxic contaminants in twelve urban lakes in Beijing,China,to the seasonal variations in climatic factors was studied.Fluorides,volatile phenols,arsenic,selenium,and other water quality parameters were analyzed monthly from2009 to 2012.Multivariate statistical methods including principle component analysis,cluster analysis,and multiple regression analysis were performed to study the relationship between contaminants and climatic factors including temperature,precipitation,wind speed,and sunshine duration.Fluoride and arsenic concentrations in most urban lakes exhibited a significant positive correlation with temperature/precipitation,which is mainly caused by rainfall induced diffuse pollution.A negative correlation was observed between volatile phenols and temperature/precipitation,and this could be explained by their enhanced volatilization and biodegradation rates caused by higher temperature.Selenium did not show a significant response to climatic factor variations,which was attributed to low selenium contents in the lakes and soils.Moreover,the response degrees of contaminants to climatic variations differ among lakes with different contamination levels.On average,temperature/precipitation contributed to 8%,15%,and 12%of the variations in volatile phenols,arsenic,and fluorides,respectively.Beijing is undergoing increased temperature and heavy rainfall frequency during the past five decades.This study suggests that water quality related to fluoride and arsenic concentrations of most urban lakes in Beijing is becoming worse under this climate change trend. | Qiong Wu Xinghui Xia Xinli Mou Baotong Zhu Pujun Zhao Haiyang Dong | 2014 | Journal of Environmental Sciences2014，26，12： | 1 |
| 15 | A joint call for actions to advance taxonomy in China显示文摘Taxonomy plays an important role in understanding the origin, evolution, and ecological functionality of biodiversity. There are large number of unknown species yet to be described by taxonomists, which together with their ecosystem services cannot be effectively protected prior to description. Despite this, taxonomy has been increasingly underrated insufficient funds and permanent positions to retain young talents. Further, the impact factordriven evaluation systems in China exacerbate this downward trend, so alternative evaluation metrics are urgently necessary. When the current generation of outstanding taxonomists retires,there will be too few remaining taxonomists left to train the next generation. In light of these challenges, all co-authors worked together on this paper to analyze the current situation of taxonomy and put out a joint call for immediate actions to advance taxonomy in China. | Chaodong Zhu Arong Luo Ming Bai Michael COrr Zhonge Hou Siqin Ge Jun Chen Yibo Hu Xuming Zhou Gexia Qiao Hongzhi Kong Limin Lu Xiaohua Jin Lei Cai Xinli Wei Ruilin Zhao Wei Miao Qingfeng Wang Zhongli Sha Qiang Lin Meng Qu Jianping Jiang Jiatang Li Jing Che Xuelong Jiang Xiaoyong Chen Lianming Gao Zongxin Ren Chunlei Xiang Shixiao Luo Donghui Wu Dong Liu Yanqiong Peng Tao Su Chenyang Cai Tianqi Zhu Wanzhi Cai Xingyue Liu Hu Li Huaijun Xue Zhen Ye Xuexin Chen Pu Tang Shujun Wei Hong Pang Qiang Xie Feng Zhang Feng Zhang Xianjin Peng Aibing Zhang Taiping Gao Changfa Zhou Chen Shao Libin Ma Zhaoming Wei Yunxia Luan Ziwei Yin Wu Dai Cong Wei Xiaolei Huang Jingxian Liu Xiangsheng Chen Tianci Yi Zhisheng Zhang Zhulidezi Aishan Qin Li Hongying Hu | 2022 | Zoological Systematics2022，47，3： | 1 |
| 16 | Sonochemical synthesis of polyaniline nanofibers 显示文摘 | Jing Xinli Wang Yangyong Wu Dan | 2007 | Ultrasonics Sono- chemistry2007，14，1： | 1 |
| 17 | Polyaniline nanofibers prepared with ultrasonic irradiation 显示文摘 | Jing Xinli Wang Yangyong Wu Dan | 2006 | Journal of Polymer Science Part A: Polymer Chemistry2006，44，2： | 1 |
| 18 | 显示文摘 | Xinli Jing Yangyong Wang Dan Wu | 2006 | J Polym Sci Pol Chem2006，44，： | 1 |
| 19 | 显示文摘 | Xinli Jing Yangyong Wang Dan Wu Jipeng Qiang | 2007 | Ultrason Sonochem2007，14，： | 1 |
| 20 | Erianin suppresses constitutive activation of MAPK signaling pathway by inhibition of CRAF and MEK1/2显示文摘Constitutive activation of RAS-RAF-MEK-ERK signaling pathway(MAPK pathway)frequently occurs in many cancers harboring RAS or RAF oncogenic mutations.Because of the paradoxical activation induced by a single use of BRAF or MEK inhibitors,dual-target RAF and MEK treatment is thought to be a promising strategy.In this work,we evaluated erianin is a novel inhibitor of CRAF and MEK1/2 kinases,thus suppressing constitutive activation of the MAPK signaling pathway induced by BRAF V600E or RAS mutations.KinaseProfiler enzyme profiling,surface plasmon resonance(SPR),isothermal titration calorimetry(ITC),cellular thermal shift assay,computational docking,and molecular dynamics simulations were utilized to screen and identify erianin binding to CRAF and MEK1/2.Kinase assay,luminescent ADP detection assay,and enzyme kinetics assay were investigated to identify the efficiency of erianin in CRAF and MEK1/2 kinase activity.Notably,erianin suppressed BRAF V600E or RAS mutant melanoma and colorectal cancer cell by inhibiting MEK1/2 and CRAF but not BRAF kinase activity.Moreover,erianin attenuated melanoma and colorectal cancer in vivo.Overall,we provide a promising leading compound for BRAF V600E or RAS mutant melanoma and colorectal cancer through dual targeting of CRAF and MEK1/2. | Penglei Wang Xuechao Jia Bingbing Lu Han Huang Jialin Liu Xuejiao Liu Qiong Wu Yamei Hu Pan Li Huifang Wei Tingting Liu Dengyun Zhao Lingwei Zhang Xueli Tian Yanan Jiang Yan Qiao Wenna Nie Xinli Ma Ruihua Bai Cong Peng Zigang Dong Kangdong Liu | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员