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| 1 | Long-range optical trapping and binding of microparticles in hollow-core photonic crystal fibre显示文摘Optically levitated micro-and nanoparticles offer an ideal playground for investigating photon–phonon interactions over macroscopic distances.Here we report the observation of long-range optical binding of multiple levitated microparticles,mediated by intermodal scattering and interference inside the evacuated core of a hollow-core photonic crystal fibre(HC-PCF).Three polystyrene particles with a diameter of 1μm are stably bound together with an inter-particle distance of~40μm,or 50 times longer than the wavelength of the trapping laser.The levitated boundparticle array can be translated to-and-fro over centimetre distances along the fibre.When evacuated to a gas pressure of 6 mbar,the collective mechanical modes of the bound-particle array are able to be observed.The measured interparticle distance at equilibrium and mechanical eigenfrequencies are supported by a novel analytical formalism modelling the dynamics of the binding process.The HC-PCF system offers a unique platform for investigating the rich optomechanical dynamics of arrays of levitated particles in a well-isolated and protected environment. | Dmitry S.Bykov Shangran Xie Richard Zeltner Andrey Machnev Gordon K.L.Wong Tijmen G.Euser Philip St.J.Russell | 2018 | Light(Science & Applications)2018，7，1： | 3 |
| 2 | A vision based row detection system for sugar beet 显示文摘 | Tijmen Bakker Hendrik Wouters Kees Van Asselt | 2008 | Computers and Electronics in Agriculture2008，60，1： | 1 |
| 3 | A vision based row detection system for sugar beet 显示文摘 | Tijmen Bakker Hendrik Wouters Kees van Asseh | 2008 | Computers and Electronics in Agricuhure2008，60，1： | 1 |
| 4 | A vision based row detection system for sugar beet 显示文摘 | Tijmen Bakker Hendrik Wouters Kees van Asselt | 2008 | Com- puters and Electronics in Agrieuhure2008，60，1： | 1 |
| 5 | Surface Structure of Untreated Parallel and Fishbone Carbon Nanofibres: An Infrared Study显示文摘 | Tijmen GeorgeRos Adrianus Jacobusvan Dillen John WilhelmGeus Diederik ChristiaanKoningsberger | 2002 | ChemPhysChem2002，，2： | 1 |
| 6 | A vision based row detection system for sugar beet 显示文摘 | Tijmen Bakkera Hendrik Woutersa Kees van Asseha | 2008 | Computers and Electronics in Agriculture2008，60，1： | 1 |
| 7 | Sensitive capacitive pressure sensors based on graphene membrane arrays显示文摘The high flexibility,impermeability and strength of graphene membranes are key properties that can enable the next generation of nanomechanical sensors.However,for capacitive pressure sensors,the sensitivity offered by a single suspended graphene membrane is too small to compete with commercial sensors.Here,we realize highly sensitive capacitive pressure sensors consisting of arrays of nearly ten thousand small,freestanding double-layer graphene membranes.We fabricate large arrays of small-diameter membranes using a procedure that maintains the superior material and mechanical properties of graphene,even after high-temperature annealing.These sensors are readout using a low-cost battery-powered circuit board,with a responsivity of up to 47:8aF Pa^(−1) mm^(−2),thereby outperforming the commercial sensors. | Makars Siskins Martin Lee Dominique Wehenkel Richard van Rijn Tijmen W.de Jong Johannes R.Renshof Berend C.Hopman Willemijn S.J.M.Peters Dejan Davidovikj Herre S.J.van der Zant Peter G.Steeneken | 2020 | Microsystems & Nanoengineering2020，6，1： | 1 |
| 8 | A vision based row detection system for sugar beet显示文摘 | Tijmen Bakker Hendfik Wouters Kees van Asseh | 2008 | Computers and Electronics in Agriculture2008，60，： | 1 |
| 9 | -Systematic design of an autonomous platform for robotic weeding 显示文摘 | Tijmen B Kees A Jan B | 2010 | Journal of Terramechanics2010，47，2： | 1 |
| 10 | In vitro 3D phenotypic drug screen identifies celastrol as an effective in vivo inhibitor of polycystic kidney disease显示文摘Polycystic kidney disease(PKD)is a prevalent genetic disorder,characterized by the formation of kidney cysts that progressively lead to kidney failure.The currently available drug tolvaptan is not well tolerated by all patients and there remains a strong need for alternative treatments.The signalling rewiring in PKD that drives cyst formation is highly complex and not fully understood.As a consequence,the effects of drugs are sometimes difficult to predict.We previously established a high-throughput microscopy phenotypic screening method for quantitative assessment of renal cyst growth.Here,we applied this 3D cyst growth phenotypic assay and screened 2320 small drug-like molecules,including approved drugs.We identified 81 active molecules that inhibit cyst growth.Multi-parametric phenotypic profiling of the effects on 3D cultured cysts discriminated molecules that showed preferred pharmacological effects above genuine toxicological properties.Celastrol,a triterpenoid from Tripterygium wilfordii,was identified as a potent inhibitor of cyst growth in vitro.In an in vivo iKspCre-Pkd1^lox,lox mouse model for PKD,celastrol inhibited the growth of renal cysts and maintained kidney function. | Tijmen H.Booij Wouter N.Leonhard Hester Bange Kuan Yan Michiel Fokkelman Anna J.Plugge Kimberley A.M.Veraar Johannes G.Dauwerse Gerard J.P.van Westen Bob van de Water Leo S.Price Dorien j.M.Peters | 2020 | Journal of Molecular Cell Biology2020，12，8： | 1 |
| 11 | Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn’s disease patients显示文摘 | Henri Braat Pieter Stokkers Tijmen Hommes Danny Cohn Esther Vogels Inge Pronk Arnold Spek Antoine Kampen Sander Deventer Maikel Peppelenbosch Daan Hommes | 2005 | Journal of Molecular Medicine2005，，8： | 1 |
| 12 | A vision based row detection system for sugar beet显示文摘 | Tijmen Bakker Hendrik Wouters Kees van Asselt Jan Bontsema Lie Tang Joachim Müller Gerrit van Straten | 2007 | Computers and Electronics in Agriculture2007，，1： | 1 |
| 13 | Surface oxidation of carbon nanofibres显示文摘 | Tijmen G Adrianus J Van Dillen A John W Geus Prof Diederik C Koningsberger | | 0，，05： | 1 |
| 14 | A path following algorithm for mobile robots显示文摘 | Tijmen Bakker Kees van Asselt Jan Bontsema etal | 2010 | Auton Robot2010，，29： | 1 |
| 15 | Giant mid-IR resonant coupling to molecular vibrations in sub-nm gaps of plasmonic multilayer metafilms显示文摘Nanomaterials capable of confining light are desirable for enhancing spectroscopies such as Raman scattering,infrared absorption,and nonlinear optical processes.Plasmonic superlattices have shown the ability to host collective resonances in the mid-infrared,but require stringent fabrication processes to create well-ordered structures.Here,we demonstrate how short-range-ordered Au nanoparticle multilayers on a mirror,self-assembled by a sub-nm molecular spacer,support collective plasmon-polariton resonances in the visible and infrared,continuously tunable beyond 11 pm by simply varying the nanoparticle size and number of layers.The resulting molecule-plasmon system approaches vibrational strong coupling,and displays giant Fano dip strengths,SEIRA enhancement factors~106,light-matter coupling strengths g~100 cm-1,Purcell factors~106,and mode volume compression factors~108.The collectiive plasmon-polariton mode is highly robust to nanoparticle vacancy disorder and is sustained by the consistent gap size defined by the molecular spacer.Structural disorder efficiently couples light into the gaps between the multilayers and mirror,enabling Raman and infrared sensing of sub-picolitre sample volumes. | Rakesh Arul David-Benjamin Grys Rohit Chikkaraddy Niclas S.Mueller Angelos Xomalis Ermanno Miele Tijmen Geuser Jeremy J.Baumberg | 2022 | Light(Science & Applications)2022，11，10： | 0 |
| 16 | The Prognostic Value of Myocardial Deformation in Patients with Congenital Aortic Stenosis显示文摘Aims:To assess the prognostic value of left ventricular(LV)global longitudinal strain(GLS)and global longitudinal early diastolic strain rate(GLSre)with regard to cardiovascular events,as congenital aortic stenosis(AoS)is associated with significant mortality and morbidity but predictors for clinical outcome are scarce.Strain analysis provides a robust and reproducible method for early detection of LV dysfunction,which might be of prognostic value.Methods:This prospective study,included clinically stable patients with congenital AoS between 2011–2013.LV GLS and GLSre was performed in the apical 4,3 and 2-chamber views using Tomtec software.The endpoint was a composite of death,heart failure,hospitalization,arrhythmia,thrombo-embolic events and re-intervention.Results:In total 138 patients were included(33[26–43]years,86(62%)male),NYHA class I:134(97%).Mean LV GLS was–15.3±3.2%,GLSre 0.66±0.18 s–1.Both correlated with NT-proBNP,LV volumes and ejection fraction(strongest LV GLS with LV EF:r–0.539,p<0.001,strongest LV GLSre with age:r–0.376,p<0.001).During median follow-up of 5.9[5.5–6.2]years,the endpoint occurred in 53(38%)patients:4 patients died,9 developed heart failure,22 arrhythmias,8 thrombo-embolic events and 35 re-interventions.Both LV GLS(standardized HR(sHR 0.62(95%CI 0.47–0.81)and GLSre(sHR 0.62(95%CI 0.47–0.83)were associated with the endpoint.Additional multivariable analysis showed that both GLS and GLSre were associated independent of left atrial volume,NT-proBNP and prior re-interventions.Conclusion:Left ventricular GLS and GLSre are reduced in adult patients with congenital AoS.Both markers are associated with adverse cardiac events and have clear clinical relevance. | Roderick W.J.van Grootel Allard T.van den Hoven Dan Bowen Tijmen Ris Jolien W.Roos-Hesselink Annemien E.van den Bosch | 2021 | Congenital Heart Disease2021，16，3： | 0 |
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