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| 1 | Hepatitis C virus therapy with peg-interferon and ribavirin in Myanmar: A resource-constrained country显示文摘AIM To investigate peg-interferon(peg-IFN) and ribavirin(RBV) therapy in Myanmar and to predict sustained virologic response(SVR).METHODS This single-center, open-label, study was conducted in Myanmar between 2009 and 2014. A total of 288 patients infected with HCV genotypes 1, 2, 3 and 6 were treated with peg-IFN alpha-2a(180 μg/wk) or alpha-2b(50 to 100 μg as a weight-based dose) and RBV as a weight-based dose(15 mg/kg/d). Treatment duration was 48 wk for genotypes 1 and 6, 24 wk for genotype 2, and 24 or 48 wk for genotype 3 based on rapid virologic response(RVR). Those co-infected with hepatitis B received 48 wk of therapy.RESULTS Overall, SVR was achieved for 82% of patients and the therapy was well tolerated. All patients achieved SVR at equivalent rates regardless of HCV genotype(P = 0.314). Low fibrosis scores(P < 0.001), high baseline albumin levels(P = 0.028) and low baseline viral loads(P = 0.029) all independently predicted SVR. On the other hand, IL-28 B TT and CC genotypes were not found to significantly predict SVR(P = 0.634; P = 0.618). Among those who completed treatment, the occurrence of RVR showed a > 96% positive predictive value for achieving SVR. Treatment duration did not significantly impact the likelihood of achieving SVR for patients infected with genotype 3 HCV(P = 0.371). The most common adverse events were fatigue(71%) and poor appetite(60%). Among patients with genotype 3 HCV, more patients in the 48-wk treatment group required erythropoietin than in the 24-wk treatment group(61.1% vs 49.2%).CONCLUSION SVR rates were high with peg-IFN and RBV therapy in Myanmar. Fibrosis scores, baseline albumin, HCV RNA levels and RVR independently predicted SVR. | Naomi Khaing Than Hlaing Debolina Banerjee Robert Mitrani Soe Htet Arker Kyaw San Win Nyan Lin Tun Zaw Thant Khin Maung Win K Rajender Reddy | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 2 | Does the spatial arrangement of urban landscape matter?Examples of urban warming and cooling in Phoenix and Las Vegas显示文摘This study examines the impact of spatial landscape configuration(e.g.,clustered,dispersed)on land-surface temperatures(LST)over Phoenix,Arizona,and Las Vegas,Nevada,USA.We classified detailed land-cover types via object-based image analysis(OBIA)using Geoeye-1 at 3-m resolution(Las Vegas)and QuickBird at 2.4-m resolution(Phoenix).Spatial autocorrelation(local Moran’s I)was then used to test for spatial dependence and to determine how clustered or dispersed points were arranged.Next,we used Advanced Spaceborne Thermal Emission and Reflection Radiometer(ASTER)data acquired over Phoenix(daytime on 10 June and nighttime on 17 October 2011)and Las Vegas(daytime on 6 July and nighttime on 27 August 2005)to examine day-and nighttime LST with regard to the spatial arrangement of anthropogenic and vegetation features.Local Moran’s I values of each land-cover type were spatially correlated to surface temperature.The spatial configuration of grass and trees shows strong negative correlations with LST,implying that clustered vegetation lowers surface temperatures more effectively.In contrast,clustered spatial arrangements of anthropogenic land-cover types,especially impervious surfaces and open soil,elevate LST.These findings suggest that city planners and managers should,where possible,incorporate clustered grass and trees to disperse unmanaged soil and paved surfaces,and fill open unmanaged soil with vegetation.Our findings are in line with national efforts to augment and strengthen green infrastructure,complete streets,parking management,and transit-oriented development practices,and reduce sprawling,unwalkable housing development. | Soe Win Myint Baojuan Zheng Emily Talen Chao Fan Shai Kaplan Ariane Middel Martin Smith Huei-Ping Huang Anthony Brazel | 2015 | Ecosystem Health and Sustainability2015，1，4： | 2 |
| 3 | Renal histopathology following Russell' s viper (Vipera russelli) bite显示文摘 | Soe S Win MM Htwe TT | 1993 | The Southeast Asian Journal of Tropical Medicine and Public Health1993，24，1： | 1 |
| 4 | Alzheimer's disease and type 2 diabetes mellitus: Risk factors and effectiveness of antidiabetic agents in treatment of Alzheimer' s disease 显示文摘 | Aye Aye Myint Kyaw Soe Win Zaw Aung | 2013 | Science J Clin Med2013，2，3： | 1 |
| 5 | Public awareness,attitude and understanding toward epilepsy among Myanmar people显示文摘 | Win NN Soe C | 2002 | Neurol J Southeast Asia2002，7，： | 1 |
| 6 | An Evaluation of four different wavelet decomposition procedures for spatial feature discrimination in urban areas显示文摘 | Soe Win Myint Nina Lam John Tyler | 2002 | Transaction in GIS2002，6，4： | 1 |
| 7 | The Seismicity and Seismological Work of Myanmar显示文摘In this report, the set up, responsibility and objectives of the seismological division of Myanmar are briefly presented. A general description of the seismotectonics and seismicity in Myanmar is given. The activities of the seismological division in monitoring earthquakes and in international cooperation are also described. | Soe Win Aye Ko | 2002 | Earthquake Research in China2002，16，3： | 1 |
| 8 | An evaluation of four different wavelet decomposition procedures for spatial feature discrimination in urban areas显示文摘 | Soe Win Myint Nina Lam John Tyler | | Transactions in GIS0，6，4： | 1 |
| 9 | Observed characteristics of flow,water mass,and turbulent mixing in the Preparis Channel显示文摘Preparis Channel is the very important exchange path of energy and materials between the northern Bay of Bengal and Andaman Sea(AS).A set of hydrographic measurements,a microstructure profiler,and a deep mooring were used to determine the characteristics of water masses,turbulent mixing,and flows in the Preparis Channel.The unprecedented short-term mooring data reveal that a deep current in the deep narrow passage(below 400 m)of the Preparis Channel flows toward the Bay of Bengal(BoB)with a mean along-stream velocity of 25.26 cm/s at depth of 540 m;above the deep current,there are a relatively weak current flows toward the AS with a mean along-stream velocity of 15.46 cm/s between 500 m and 520 m,and another weak current flows toward the BoB between 430 m and 500 m.Thus,a sandwiched vertical structure of deep currents(below 400 m)is present in the Preparis Channel.The volume transport below 400 m is 0.06 Sv(1 Sv=106 m^(3)/s)from the AS to the BoB.In the upper layer(shallower than 300 m),the sea water of the AS is relatively warmer and fresher than that in the BoB,indicating a strong exchange through the channel.Microstructure profiler observations reveal that the turbulent diffusivity in the upper layer of the Preparis Channel reaches O(10−4 m^(2)/s),one order larger than that in the interior of the BoB and over the continental slope of the northern AS.We speculate that energetic high-mode internal tides in the Preparis Channel contribute to elevated turbulent mixing.In addition,a local“hotspot”of turbidity is identified at the deep mooring site,at depth of about 100 m,which corresponds to the location of elevated turbulent mixing in the Preparis Channel. | Ruijie Ye Feng Zhou Xiao Ma Dingyong Zeng Feilong Lin Hongliang Li Chenggang Liu Soe Moe Lwin Hlaing Swe Win Soe Pyae Aung | 2023 | Acta Oceanologica Sinica2023，42，2： | 0 |
| 10 | Chemical analysis of hydroquinone and retinoic acid contents in facial whitening creams显示文摘Hydroquinone is potentially carcinogenic and is known to be a skin and respiratory irritant.Hydroquinone is carcinogenic it has been banned in some countries because of fears of a cancer risk[1,2].Animal studies have shown that topically applied retinoic acid can be photocarcinogenic[3].The aim of this study was qualitative and quantitative determination of hydroquinone and retinoic acid contents in facial whitening creams by colour reaction tests,FT-IR after TLC separation and HPLC. | Aung Myo Htet Ei Ei Thin Mi Mi Saw Soe Win | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，1： | 0 |
| 11 | International non-governmental organizations’provision of communitybased tuberculosis care for hard-to-reach populations in Myanmar,2013-2014显示文摘Background:National tuberculosis(TB)programs increasingly engage with international non-governmental organizations(INGOs),especially to provide TB care in complex settings where community involvement might be required.In Myanmar,however,there is limited data on how such INGO community-based programs are organized and how effective they are.In this study,we describe four INGO strategies for providing community-based TB care to hard-to-reach populations in Myanmar,and assess their contribution to TB case detection.Methods:We conducted a descriptive study using program data from four INGOs and the National TB Program(NTP)in 2013-2014.For each INGO,we extracted information on its approach and key activities,the number of presumptive TB cases referred and undergoing TB testing,and the number of patients diagnosed with TB and their treatment outcomes.The contribution of INGOs to TB diagnosis in their selected townships was calculated as the proportion of INGO-diagnosed new TB cases out of the total NTP-diagnosed new TB cases in the same townships.Results:All four INGOs implemented community-based TB care in challenging contexts,targeting migrants,post-conflict areas,the urban poor,and other vulnerable populations.Two recruited community volunteers via existing community health volunteers or health structures,one via existing community leaderships,and one directly involved TB infected/affected individuals.Two INGOs compensated volunteers via performance-based financing,and two provided financial and in-kind initiatives.All relied on NTP laboratories for diagnosis and TB drugs,but provided direct observation treatment support and treatment follow-up.A total of 21995 presumptive TB cases were referred for TB diagnosis,with 7383(34%)new TB cases diagnosed and almost all(98%)successfully treated.The four INGOs contributed to the detection of,on average,36%(7383/20663)of the total new TB cases in their respective townships(range:15-52%).Conclusion:Community-based TB care supported by INGOs successfully achieved TB case detection in hard-toreach and vulnerable populations.This is vital to achieving the World Health Organization End TB Strategy targets.Strategies to ensure sustainability of the programs should be explored,including the need for longer-term commitment of INGOs. | Kyaw Thu Soe Saw Saw Johan van Griensven Shuisen Zhou Le Win Palanivel Chinnakali Safieh Shah Myo Myo Mon Si Thu Aung | 2017 | Infectious Diseases of Poverty2017，6，1： | 0 |
| 12 | Fish Species Diversity in Upstream and Downstream of Sittaung River,Bago Region,Myanmar显示文摘This research was conducted to generate a primary database on ichthyofauna,distribution and diversities in the upstream and downstream segments of Sittaung River in Bago Region of Myanmar.This study contributes to the information needed on the distribution of river fish in Myanmar.Fish diversities are assessed by calculating the various diversities indices between December,2018 and November,2019.A total of 65 fish species belonging to 9 orders,23 families and 49 genera were recorded.All 65 fish species were found in upstream segment but only 60 species of them were found in downstream segment of the river.In all study sites,Shannon diversity index had value above 3 indicating that the structure of habitat was stable and balanced.Simpson’s index values were close to 1 in all sites indicating that the species richness in the region was satisfactory.The abundance all of above 5%of total catch of Mystus vittatus,M.pulcher,M.cavasius and Erethistes pusillus in their feeding habitat suggested that their upstream and downstream habitats provided suitable feeding conditions.Anguilla bengalensis,Tenualosa ilisha,Mystus gulio,Rita rita and Silonia silondia were least abundant all below 0.1%of total catch showing they could be impacted by unwise anthropogenic activities.Assessing fish species diversity is thus very important to conserve and manage and promote the health of river ecosystem that is necessary for the migration of fish species. | Toe Toe Soe San San Oo Khin Thuzar Win Nyo Nyo Aung Aye Aye Su Khine Wai Yin Nu Hninn Kyaing Win Win Than | 2020 | Journal of Environmental Science and Engineering(A)2020，9，4： | 0 |
| 13 | Seismic Microzonation of Mandalay City, Myanmar显示文摘 | Pyi Soe Thein Junji Kiyono Tun Tun Win Than Than Nu Day Wa Aung | 2018 | Journal of Geological Resource and Engineering2018，6，1： | 0 |
| 14 | Participation of private general practitioners in disease management of malaria in Myanmar显示文摘Objective:Myanmar has been trying to improve the disease management of malaria through public health services. The involvement of private general practitioners(GPs) is recognized as one of the key contributory issues in malaria control,but no one has yet made an attempt to study the efficiency of their role.This study aimed to assess the participation of GPs in improvement of disease management.Methods:The study was conducted with all 32 GPs practicing at three randomly selected townships with high malaria load situated in Upper Myanmar from June 2006 to March 2007 using a pretest-posttest design to assess their knowledge of the disease management prior to and after intervention.The intervention package consisted of a one-day workshop on diagnosis and treatment of malaria and the supply of facilities for microscopy.Questionnaires filled in before and after tests were compared to assess the change of knowledge after the intervention.Diagnosis and treatment practice during the study period was analysed by review of registers kept by GPs,together with a follow-up survey of their patients for the reliability of data.Results:An overall improvement of knowledge was observed and significant changes were apparent for three variables:the criteria for referral of severe malaria,the effect of incomplete treatment and recommended treatment of Plasmodium vivax.Pre-test results showed that only 65.6%of GPs perceived microscopy or Rapid Diagnostic Test kits(RDTs) for confirmation of malaria necessary,while only 15.6%and 40.6%of the GPs knew the recommended treatments of falciparum and vivax malaria,respectively. However,after intervention 92%of the patients were diagnosed as malaria by RDTs and 3%by microscopy throughout the study.The GPs prescribed artemisinin-based combination therapy(ACTs) to 95%of confirmed falciparum cases and treated 82.4%of RDT confirmed falciparum negatives with chloroquine and primaquine.Concurrent with our study,an international NGO,Population Service International,supplied GPs with RDTs and ACTs at subsidized rate which was helpful.Conclusion:The study suggests that participation of GPs may help improve the disease management of malaria and thus assist in the country’s effort to control ma- laria. | Thein Tun Zaw Win Tun Hla Soe Tint Khin Lin Thar Tun Kyaw Moe Kyaw Myint | 2009 | Asian Pacific Journal of Tropical Medicine2009，2，5： | 0 |
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