|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Upper esophageal sphincter abnormalities are strongly predictive of treatment response in patients with achalasia显示文摘AIM: To investigate the relationship between upper esophageal sphincter abnormalities achalasia treatment METHODS: We performed a retrospective study of 41 consecutive patients referred for high resolution esophageal manometry with a final manometric diagnosis of achalasia. Patients were sub-divided by presence or absence of Upper esophageal sphincter(UES) abnormality, and clinical and manometric profiles were compared.Correlation between UES abnormality and sub-type(i.e.,hypertensive, hypotensive or impaired relaxation) and a number of variables, including qualitative treatment response, achalasia sub-type, co-morbid medical illness,psychiatric illness, surgical history, dominant presentingsymptom, treatment type, age and gender were also evaluated.RESULTS: Among all 41 patients, 24(58.54%) had a UES abnormality present. There were no significant differences between the groups in terms of age, gender or any other clinical or demographic profiles. Among those with UES abnormalities, the majority were either hypertensive(41.67%) or had impaired relaxation(37.5%) as compared to hypotensive(20.83%), although this did not reach statistical significance(P = 0.42). There was no specific association between treatment response and treatment type received; however, there was a significant association between UES abnormalities and treatment response. In patients with achalasia and concomitant UES abnormalities, 87.5% had poor treatment response, while only 12.5% had favorable response. In contrast, in patients with achalasia and no UES abnormalities, the majority(78.57%) had good treatment response, as compared to 21.43% with poor treatment response(P = 0.0001). After controlling for achalasia sub-type, those with UES abnormality had 26 times greater odds of poor treatment response than those with no UES abnormality(P = 0.009). Similarly, after controlling for treatment type, those with UES abnormality had 13.9 times greater odds of poor treatment response compared to those with no UES abnormality(P = 0.017).CONCLUSION: The presence of UES abnormalities in patients with achalasia significantly predicted poorer treatment response as compared to those with normal UES function. | Simon C Mathews Maria Ciarleglio Yamile Haito Chavez John O Clarke Ellen Stein Bani Chander Roland | 2014 | World Journal of Clinical Cases2014，2，9： | 5 |
| 2 | Effect of charcoal quantity on microbial biomass and activity in temperate soils 显示文摘 | Simone E K Kevin J F Mathew E D | 2009 | Soil Science Society of America Journal2009，73，4： | 1 |
| 3 | mir-210:a sensor for hypoxic stress during tumorigenesis显示文摘 | Mathew L K Simon M C | 2009 | Mol Cell2009，35，： | 1 |
| 4 | EFFICACY AND SAFETY OF DOPAMINE VERSUS NOREPINEPHRINE IN THE MANAGEMENT OF SEPTIC SHOCK显示文摘 | Gourang P. Patel Jaime Simon Grahe Mathew Sperry Sunit Singla Ellen Elpern Omar Lateef Robert A. Balk | 2010 | Shock2010，，4： | 1 |
| 5 | mir-210:a sensor for hy-poxic stress during tumorigenesis显示文摘 | Lijoy K Mathew M Celeste Simon | 2009 | Mol Cell2009，35，6： | 1 |
| 6 | Anti-cancer activities of novel D-ring modified 2-substituted estrogen- 3-O-sulfamates 显示文摘 | Mathew P L Bertrand L Simon P N | 2005 | Journal of Steroid Biochemistry & Molecular Biology2005，94，1： | 1 |
| 7 | Endothelial HIF-2[alpha] regulates murine pathological angiogenesis and revascularization processes显示文摘 | Skuli Nicolas Majmundar Amar J Krock Bryan L Mesquita Rickson C Mathew Lijoy K Quinn Zachary L Runge Anja Liu Liping Kim Meeri N Liang Jiaming Schenkel Steven Yodh Arjun G Keith Brian Simon M Celeste | 2012 | EN2012，，4： | 1 |
| 8 | 25-Year summary of US malpractice claims for diagnostic errors 1986–2010: an analysis from the National Practitioner Data Bank显示文摘 | Ali S Saber Tehrani HeeWon Lee Simon C Mathews Andrew Shore Martin A Makary Peter J Pronovost David E Newman-Toker | 2013 | BMJ Quality & Safety2013，，8： | 1 |
| 9 | An Exploration of OnlineShopping Cart Abandonment Syndrome A Matter ofRisk and Reputation显示文摘 | Simon Moore Shane Mathews | 2006 | Journal of Website Promotion2006，，1： | 1 |
| 10 | Technological Trends Product Design and the Environment显示文摘 | POOLE Stephen SIMON Mathew | 1997 | Design Studies1997，18，3： | 1 |
| 11 | 新丝绸之路出现了,而且并不通往美国显示文摘由于美国逐渐走出经济衰退,因此美国投资者时常在想,这股增长究竞源自何处。也许他们应该与巴西最大的公共汽车生产商Marcopolo公司的国际运营主管鲁本·比西谈谈。今年公司成绩喜人,截至目前公司营业额已经增长了47%。不过,在美国你看不到Marcopolo公司生产的公共汽车。它们奔驰穿梭于阿根廷、哥伦比亚、墨西哥、埃及、印度、中国和南非的高速公路和城市街道上。比西说,与跨国公司相比,巴西人与这些客户的关系通常更紧密。 | Simon Kennedy Mathew Bristow Shamim Adam | 2010 | 国际经济合作2010，，11： | 1 |
| 12 | The Effect of Human Activities on the Quality of Water at UMhlathuze River (Northern Coast of Kwa-Zulu Natal, RSA): The Case of Agricultural and Industrial Developments显示文摘 | Mathews Simon Mthembu Trayana Guegueva Djarova Albert Kotze Basson | 2012 | Journal of Agricultural Science and Technology(A)2012，2，5： | 0 |
| 13 | Nitrogen and Phosphorus Removal from Agricultural Wastewater Using Constructed Rhizofiltration in Durban, South Africa显示文摘 | Mathews Simon Mthembu | 2012 | Journal of Agricultural Science and Technology(A)2012，2，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员