|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Preliminary assessment of the navigation and positioning performance of BeiDou regional navigation satellite system显示文摘BeiDou regional navigation satellite system(BDS)also called BeiDou-2 has been in full operation since December 27,2012.It consists of 14 satellites,including 5 satellites in Geostationary Orbit(GEO),5 satellites in Inclined Geosynchronous Orbit(IGSO),and 4 satellites in Medium Earth Orbit(MEO).In this paper,its basic navigation and positioning performance are evaluated preliminarily by the real data collected in Beijing,including satellite visibility,Position Dilution of Precision(PDOP)value,the precision of code and carrier phase measurements,the accuracy of single point positioning and differential positioning and ambiguity resolution(AR)performance,which are also compared with those of GPS.It is shown that the precision of BDS code and carrier phase measurements are about 33 cm and 2 mm,respectively,which are comparable to those of GPS,and the accuracy of BDS single point positioning has satisfied the design requirement.The real-time kinematic positioning is also feasible by BDS alone in the opening condition,since its fixed rate and reliability of single-epoch dual-frequency AR is comparable to those of GPS.The accuracy of BDS carrier phase differential positioning is better than 1 cm for a very short baseline of 4.2 m and 3 cm for a short baseline of 8.2 km,which is on the same level with that of GPS.For the combined BDS and GPS,the fixed rate and reliability of single-epoch AR and the positioning accuracy are improved significantly.The accuracy of BDS/GPS carrier phase differential positioning is about 35 and 20%better than that of GPS for two short baseline tests in this study.The accuracy of BDS code differential positioning is better than 2.5 m.However it is worse than that of GPS,which may result from large code multipath errors of BDS GEO satellite measurements. | YANG YuanXi LI JinLong WANG AiBing XU JunYi HE HaiBo GUO HaiRong SHEN JunFei DAI Xian | 2014 | Science China Earth Sciences2014，57，1： | 125 |
| 2 | Restoration of HBV-specific CD8+T-cell responses by sequential low-dose IL-2 treatment in non-responder patients after IFN-αtherapy显示文摘Patients with chronic hepatitis B(CHB)undergoing interferon(IFN)-α-based therapies often exhibit a poor HBeAg serological response.Thus,there is an unmet need for new therapies aimed at CHB.This study comprised two clinical trials,including 130 CHB patients,who were treatment-naïve;in the first,92 patients were systematically analyzed ex vivo for interleukin-2 receptor(IL-2R)expression and inhibitory molecules expression after receiving Peg-IFN-α-2b therapy.In our second clinical trial,38 non-responder patients,in whom IFN-αtherapy had failed,were treated with or without low-dose IL-2 for 24 weeks.We then examined the hepatitis B virus(HBV)-specific CD8+T-cell response and the clinical outcome,in these patients.Although the majority of the participants undergoing Peg-IFN-α-2b therapy were non-responders,we observed a decrease in CD25 expression on their CD4+T cells,suggesting that IFN-αtherapy may provide a rationale for sequential IL-2 treatment without increasing regulatory T cells(Tregs).Following sequential therapy with IL-2,we demonstrated that the non-responders experienced a decrease in the numbers of Tregs and programmed cell death protein 1(PD-1)expression.In addition,sequential IL-2 administration rescued effective immune function,involving signal transducer and activator of transcription 1(STAT1)activation.Importantly,IL-2 therapy significantly increased the frequency and function of HBV-specific CD8+T cells,which translated into improved clinical outcomes,including HBeAg seroconversion,among the non-responder CHB patients.Our findings suggest that sequential IL-2 therapy shows efficacy in rescuing immune function in non-responder patients with refractory CHB. | Dongyao Wang Binqing Fu Xiaokun Shen Chuang Guo Yanyan Liu Junfei Zhang Rui Sun Ying Ye Jiabin Li Zhigang Tian Haiming Wei | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 1 |
| 3 | Ink Transfer and Refusal Mechanisms in Waterless Offset Printing 显示文摘 | Tian Junfei Mao Yu Shen Wei | 2009 | Journal of Adhesion Science and Technology2009，，23： | 1 |
| 4 | Absorption in one-dimensional metallic-dielectric photonic crystals 显示文摘 | Yu Junfei Shen Yifeng Liu Xiaohan | 2004 | J Phys: Condens Matter2004，16，： | 1 |
| 5 | Numerical simulation of the liquid steel flow and solidification phenomena in the slab continuous casting process显示文摘A 3D coupling mathematical simulation program of the fluid flow,thermal transfer and solidification was developed based on the slab continuous casting process.Some characteristics such as fluid flow,solidification and temperature distribution near the submerged entry nozzle (SEN) and the corner of the mold were simulated and analyzed.The result of the calculation indicates that the flow of molten metal forms two big cycling zones in the mold after it flows out of the SEN,and the temperature at the center of the two zones is relatively low.Moreover,there is a small narrow cycling zone near the narrow side of the mold due to casting.The velocity of the surface flow,the turbulent kinetic energy and the F value might reveal the relationship between the fluctuation of meniscus and the quality of the slab to some degree. | FAN Junfei SHEN Jianguo ZHI Jianjun REN Sanbing ZHAO Shunli ZHANG Yin ZHANG Jieyu HE Youduo | 2009 | Baosteel Technical Research2009，3，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员