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21篇 您的检索式：作者名="SHEMBADE"

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	题名	作者	年代	出处	被引量
1	Regulation of NF-κB signaling by the A20 deubiquitinase显示文摘NF-κ B 抄写因素是煽动性、天生的有免疫力的发信号小径的一个中央调停人。NF-κ 的激活; B 被哪个的关键发信号的分子的连接 K63 的 polyubiquitination 完成接着激活 Iκ 的成员 kinase 建筑群; B kinase (IKK ) 。Ubiquitination 是一个高度有活力的过程并且被 deubiquitinases 平衡劈开 polyubiquitin 链并且终止下游地发信号的事件。A20 deubiquitinase 是 NF-κ 的一个批评否定管理者; B 和发炎,后来 A20 缺乏的老鼠开发不受管束、自发的多器官发炎。而且,在 A20 genomic 地点的特定的多型性预先安排人到自体免疫的疾病。最近的研究也显示 A20 是在 B 房间淋巴瘤被使失去活性的重要肿瘤 suppressor。因此,指向 A20 可以为自体免疫的疾病和淋巴瘤形成新奇治疗的基础。	Noula Shembade Edward W Harhaj	2012	Cellular & Molecular Immunology2012，9，2：	22
2	Role of post-translational modifications of HTLV-1 Tax in NF-κB activation显示文摘Human T-cell leukemia virus type 1(HTLV-1),the first human retrovirus discovered,is the etiological agent of adult-T-cell leukemia/lymphoma.The HTLV-1 encoded Tax protein is a potent oncoprotein that deregulates gene expression by constitutively activating nuclear factor-κB(NF-κB).Tax activation of NF-κB is critical for the immortalization and survival of HTLV-1-infected T cells.In this review,we summarize the present knowledge on mechanisms underlying Tax-mediated NF-κB activation,with an emphasis on post-translational modifications of Tax.	Noula Shembade Edward W Harhaj	2010	World Journal of Biological Chemistry2010，1，1：	1
3	Inhibition of NF-kappaBsignaling by A20 through disruption of ubiquitin enzymecomplexes 显示文摘	Shembade N Ma A Harhaj EW	2010	Science2010，327，：	1
4	A20 inhibition of NFKB and inflammation 显示文摘	Shembade N Harhaj E	2010	Cell Cycle2010，9，13：	1
5	The ubiquitin-editing enzyme A20 requires RNFll to downregulate NF-kappaB signalling显示文摘	Shembade N Parvatiyar K Harhaj N S	2009	EMBO J2009，28，5：	1
6	Inhibition of NF-κB signaling by A20 through disruption of ubiquitin enzyme complexes显示文摘	Shembade N Ma A Harhaj EW	2010	Science2010，327，5969：	1
7	TNF pretreatment interfereswith mitochondrial apoptosis in the mouse liver by A20·-med iated down-regulation of Bax显示文摘	Sass G Shembade N D Haimerl F et a1	2007	J Immunol2007，179，10：	1
8	Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes显示文摘	Shembade N Ma A Harhaj EW	2010	Science2010，327，5969：	1
9	Tumour necrosis factor alpha (TNF)-TNF receptor 1-inducible cytoprotective proteins in the mouse liver:relevance of suppressors of cytokine signalling显示文摘	Sass G Shembade ND Tiegs G	2005	Biochem J2005，385，2：	1
10	Tumour necrosis factor alpha (TNF)-TNF receptor 1-inducible cytoprotective proteins in the mouse liver : relevance of suppressors of cytokine signalling 显示文摘	Sass G Shembade ND Tiegs G	2005	Biochem J2005，385，2：	1
11	Inhibition of NF-κB signaling by A20 through disruption of ubiquitin enzyme complexes显示文摘	Shembade N Ma A Harhaj EW		0，，10：	1
12	Inhibition of NF- kappaB signaling by A20 through disruption of ubiquitin enzyme complexes显示文摘	Shembade N Ma A Harhaj E W	2010	Science2010，327，5969：	1
13	Inhibition of NF-kappaB signaling by A20 through disruption of ubiq- uitin enzyme complexes 显示文摘	SHEMBADE N MA A HARHAJ E W	2010	Science2010，327，5969：	1
14	Human T cell leukemia virus type 1 Tax inhibits innate antiviral signaling via NF-kappaB-dependent induction of SOCS1显示文摘	Charoenthongtrakul S Zhou Q Shembade N		0，，14：	1
15	TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated downregulation of Bax显示文摘	Sass G Shembade N D Haimerl F	2007	J Immunol2007，179，10：	1
16	Essential role for TAX1BP1 in the termination of TNF-α-,IL-1-and LPS-mediated NF-κB and JNK signaling显示文摘	Shembade N Harhaj NS Liebl DJ		0，，30：	1
17	The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20显示文摘	Shembade N Harhaj NS Parvatiyar K		0，，03：	1
18	The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-κB signalling显示文摘	Shembade N Parvatiyar K Harhaj NS		0，，04：	1
19	Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes显示文摘	SHEMBADE N MA A HARHAJ EW		0，，5969：	1
20	The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation显示文摘	Shembade N Harhaj N S Yamamoto M		0，，24：	1

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