|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Long-term albumin infusion improves survival in patients with cirrhosis and ascites: An unblinded randomized trial显示文摘瞄准:在幸存上调查长期的白朊管理的效果,腹水的复发和另外的复杂并发症的发作。方法:为第一发作的腹水招收的 100 个连续病人被使随机化加人的白朊收到利尿剂第一年和 25 g 里的 25 g/wk 每二 wk 此后(组 1 ) 或利尿剂独自一个(组 2 ) 。没有肝移植,主要端点是幸存。第二等的端点是腹水的复发和另外的复杂并发症的出现。结果:中部的后续是 84 (2-120 ) 瞬间。对待白朊的病人有显著地更大的累积幸存率(Breslow test=7.05, P=0.0078 ) 并且腹水复发的更低的概率(51% 对 94% , P<0.0001 ) 。长期的白朊注入导致了 16 瞬间的幸存的吝啬的增加。结论:在第一发作的腹水以后的长期的白朊管理显著地改进病人的幸存并且减少腹水复发的风险。 | Roberto Giulio Romanelli Giorgio La Villa Giuseppe Barletta Francesco Vizzutti Fabio Lanini Umberto Arena Vieri Boddi Roberto Tarquini Pietro Pantaleo Paolo Gentilini Giacomo Laffi | 2006 | World Journal of Gastroenterology2006，12，9： | 22 |
| 2 | Adjuvant chemotherapy for resected colorectal cancermetastases:literature review and meta-analysis显示文摘Surgical resection is the only option of cure for patients with metastatic colorectal cancer(CRC). However, the risk of recurrence within 18 mo after metastasectomy is around 75% and the liver is the most frequent site of relapse. The current international guidelines recommend an adjuvant therapy after surgical resection of CRC metastases despite the lower level of evidence(based on the quality of studies in this setting). However, there is still no standard treatment and the effective role of an adjuvant therapy remains controversial. The aim of this review is to report the state-of-art of systemic chemotherapy and regional chemotherapy with hepatic arterial infusion in the management of patients after resection of metastases from CRC, with a literature review and meta-analysis of the relevant randomized controlled trials. | Giovanni Brandi Stefania De Lorenzo Margherita Nannini Stefania Curti Marta Ottone Filippo Gustavo Dall’Olio Maria Aurelia Barbera Maria Abbondanza Pantaleo Guido Biasco | 2016 | World Journal of Gastroenterology2016，22，2： | 13 |
| 3 | Long-term durable response to lenalidomide in a patient with hepatic epithelioid hemangioendothelioma显示文摘Epithelioid hemangioendothelioma(EH)is a rare tumor arising from the vascular endothelial cells of soft tissue or visceral organs.The most common visceral site is the liver,where it is often involved in a multifocal man-ner known as hepatic EH(HEH).Surgical resection with curative intent represents the gold standard therapy.When surgery is not feasible,or in cases of metastatic disease,no standard medical treatment is currently indicated.In small series,drugs with anti-angiogenic activity(such as bevacizumab,sorafenib,thalidomide,and lenalidomide)have been proposed with promising results.We describe a 73-year-old man with multifocal non-resectable HEH treated with lenalidomide.Disease status was evaluated by abdominal ultrasound and magnetic resonance every four months.The patient was treated for a total of 39 mo with prolonged disease stabilization and,at the time of writing,is still under treatment with a good tolerance profile.During a short period of treatment discontinuation,the disease showed slight progression that immediately resolved after the reintroduction of lenalidomide.Lenalidomide may represent a valid treatment option for HEH due to its anti-angiogenic and antineoplastic activities.This preliminary result merits further study in a large series. | Maria Caterina Pallotti Margherita Nannini Claudio Agostinelli Simona Leoni Valerio Di Scioscio Anna Mandrioli Cristian Lolli Maristella Saponara Stefano Pileri Luigi Bolondi Guido Biasco Maria Abbondanza Pantaleo | 2014 | World Journal of Gastroenterology2014，20，22： | 9 |
| 4 | Current status of the adjuvant therapy in uterine sarcoma: A literature review显示文摘Uterine sarcomas (US) are rare mesenchymal tumours accounting approximately for 3%–7% of all uterine cancers. Histologically, US are classified into mesenchymal tumours or mixed epithelial and mesenchymal tumours. The group of mesenchymal tumours includes uterine leiomyosarcoma (uLMS, 65% of cases), endometrial stromal sarcoma (ESS, 21%)– traditionally divided into low grade (LG-ESS) and high grade–undifferentiated uterine sarcoma (5%) and other rare subtypes such as alveolar or embryonal rhabdomyosarcoma. Despite the fact that several drugs demonstrated clinical activity in advanced or metastatic settings, the role of postoperative therapy in US remains controversial. In this review, we have summarised the current state of the art, including the chief trials on adjuvant treatment modalities in US, especially focusing on uLMS, LG-ESS and other rare histotypes. | Alessandro Rizzo Maria Abbondanza Pantaleo Maristella Saponara Margherita Nannini | 2019 | World Journal of Clinical Cases2019，7，14： | 3 |
| 5 | Unusual gastric and pancreatic metastatic renal cell carcinoma presentation 10 years after surgery and immunotherapy: A case report and a review of literature显示文摘肾的房间癌(RCC ) 是最普通的肾的肿瘤,为所有恶意的 2%-3% 的财务。尽管 RCC 被知道造血地传播,到胃的孤立的 RCC 转移是一个稀罕事件。在这篇文章,我们描述 RCC 的胃的复发 10 年以前与切除术和 interleukin-2 (IL-2 ) 对待的以后开发了 RCC 和 1 年的胰腺的复发的一个病人的临床的功课。积累的证据显示胰和胃的那变形参与应该与 RCC 的历史在任何病人被怀疑在 RCC 切除术和免疫疗法以后与胃肠的症状介绍甚至 10 年。 | Chiara Riviello Ilaria Tanini Greta Cipriani Pietro Pantaleo Carlo Nozzoli Alberto Poma Viligiardi Riccardo Andrea Valeri | 2006 | World Journal of Gastroenterology2006，12，32： | 2 |
| 6 | Sustained complete response of advanced hepatocellular carcinoma with metronomic capecitabine: a report of three cases显示文摘Background:Hepatocellular carcinoma(HCC)is one of the most frequent causes of cancer-related death.Sorafenib,a multitarget angiogenesis inhibitor,is an approved frontline treatment for advanced HCC in Western countries,although a complete response(CR)to treatment is infrequently reported.Capecitabine,an oral fluoropyrimidine,has been shown to be effect in both treatment-naïve patients and those previously treated with sorafenib.To date,how-ever,only one case of sustained CR to metronomic capecitabine has been reported.Case presentation:We describe three cases of advanced HCC treated with metronomic capecitabine where a CR was obtained.In the first case,capecitabine was administered as first line therapy;in the second case,capecitabine was used after intolerance to sorafenib;while in the third case,capecitabine was administered after sorafenib failure.Conclusion:Capecitabine is a potentially important treatment option for patients with advanced HCC and may even represent a cure in certain cases. | Giovanni Brandi Michela Venturi Stefania De Lorenzo Francesca Garuti Giorgio Frega Andrea Palloni Ingrid Garajovà Francesca Abbati Gioconda Saccoccio Rita Golfieri Maria Abbondanza Pantaleo Maria Aurelia Barbera | 2018 | Cancer Communications2018，38，1： | 2 |
| 7 | Successful multidisciplinary clinical approach and molecular characterization by whole transcriptome sequencing of a cardiac myxofibrosarcoma: A case report显示文摘BACKGROUND Cardiac tumors are rare and complex entities.Surgery represents the cornerstone of therapy,while the role of adjuvant treatment remains unclear and,in case of relapse or metastatic disease,the prognosis is very poor.Lack of prospective,randomized clinical trials hinders the generation of high level evidence for the optimal diagnostic workup and multimodal treatment of cardiac sarcomas.Herein,we describe the multidisciplinary clinical management and molecular characterization of a rare case of cardiac myxofibrosarcoma in an elderly woman.CASE SUMMARY A 73-year-old woman presented signs and symptoms of acute left-sided heart failure.Imaging examination revealed a large,left atrial mass.With suspicion of a myxoma,she underwent surgery,and symptoms were promptly relieved.Histology showed a cardiac myxofibrosarcoma,a rare histotype of cardiac sarcoma.Eight months later,disease unfortunately relapsed,and after a multidisciplinary discussion,a chemotherapy with doxorubicin and then gemcitabine was started,achieving partial radiologic and complete metabolic response,which was maintained up to 2 years and is still present.This report is focused on the entire clinical path of our patient from diagnosis to follow-up,through surgery and strategies adopted at relapse.Moreover,due to their rarity,very little is known about the molecular landscape of myxofibrosarcomas.Thus,we also performed and described preliminary genome analysis of the tumor tissue to get further insight on mechanisms involved in tumor growth,and to possibly unveil new clinically actionable targets.CONCLUSION We report a case of cardiac myxofibrosarcoma that achieved a very good prognosis due to an integrated surgical,cardiac and oncologic treatment strategy. | Maristella Saponara Valentina Indio Carmine Pizzi Elena-Daniela Serban Milena Urbini Annalisa Astolfi Pasquale Paolisso Sofia Martin Suarez Margherita Nannini Davide Pacini Valentina Agostini Ornella Leone Valentina Ambrosini Giuseppe Tarantino Stefano Fanti Fabio Niro Francesco Buia Domenico Attinà Maria Abbondanza Pantaleo | 2019 | World Journal of Clinical Cases2019，7，19： | 2 |
| 8 | Oxaliplatin, 5-fluorou- raci]/leucovorin and epirubicin as first-line treatment in ad- vanced gastric carcinoma : a phase 显示文摘 | Neri B Pantaleo P Giommoni E | 2007 | Br J Cancer2007，96，7： | 1 |
| 9 | A new headbox design featuring consistency profiling decoupled from fibre orientation response显示文摘 | Scott B Pantaleo | 1995 | Tappi1995，78，11： | 1 |
| 10 | Treatment of brain metastases of malignant melanoma with temozolomide显示文摘 | Biasco G Pantaleo MA Casadei S | 2001 | N Engl J Med2001，345，8： | 1 |
| 11 | Immunopathogenic mecha- nisms of HIV infection 显示文摘 | Fauci AS Pantaleo G Stanley S | 1996 | Ann Intern Med1996，124，7： | 1 |
| 12 | ESCO business models for biomass heating and CHP:profitability of ESCO operations in Italy and key factors assessment显示文摘 | PANTALEO A CANDELISE C BAUEN A | 2014 | Renewable & Sustainable Energy Reviews2014，30，： | 1 |
| 13 | ILNA silencing: an antiviral mechanism advances in virus research 显示文摘 | CSORBA T PANTALEO V BURGYAN J | | Advances in Virus Research0，75，9： | 1 |
| 14 | CYBERKNIFE RADIOSURGERY FOR TRIGEMINAL NEURALGIA TREATMENT: A PRELIMINARY MULTICENTER EXPERIENCE显示文摘 | Alan T. Villavicencio Michael Lim Sigita Burneikiene Pantaleo Romanelli John R. Adler Lee McNeely Steven D. Chang Laura Fariselli Melinda McIntyre Regina Bower Giovanni Broggi Jeffrey J. Thramann | 2008 | Neurosurgery2008，，3： | 1 |
| 15 | Hypersensitivity reactions related to oxaliplatin (OHP) 显示文摘 | Brandi G Pantaleo M A Galli C | 2003 | Br J Cancer2003，89，3： | 1 |
| 16 | Oxidative stress induces myeloperoxidase expression in endocardial endothelial cells from patients with chronic heart failure显示文摘 | Dr. Giampiero Rocca Antonino Stefano Ermanno Eleuteri Rita Anzalone Francesca Magno Simona Corrao Tiziana Loria Anna Martorana Claudio Gangi Marilena Colombo Fabrizio Sansone Francesco Patanè Felicia Farina Mauro Rinaldi Francesco Cappello Pantaleo Giannu | 2009 | Basic Research in Cardiology2009，，3： | 1 |
| 17 | Using insulin as a drug rather than as a replacement hormone during acute illness: a new paradigm 显示文摘 | Pantaleo A Zonszein J | 2003 | Heart Dis2003，5，5： | 1 |
| 18 | New concepts in the immunopathogenesis of HIV infection 显示文摘 | Pantaleo G Fauci AS | 1995 | Annu Rev Immunol1995，13，： | 1 |
| 19 | Dural sinus thrombosis in spontaneous intracranial hypotension显示文摘 | Mario Savoiardo Silvia Armenise Pantaleo Spagnolo | 2006 | J Neurol2006，253，9： | 1 |
| 20 | Characterization of Some Typical Soils of the Miombo Woodland Ecosystem of Kitonga Forest Reserve, Iringa, Tanzania: Physico-Chemical Properties and Classification显示文摘 | Hassan Bashiru Shelukindo Balthazar Msanya Ernest Semu Sibaway Mwango Bal Ram Singh Pantaleo Munishi | 2014 | Journal of Agricultural Science and Technology(A)2014，4，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员