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| 1 | Effects of applying lactic acid bacteria to the fermentation on a mixture of corn steep liquor and air-dried rice straw显示文摘This study was to determine the fermentation quality of a mixture of corn steep liquor(CSL)(178 g/kg wet basis) and air-dried rice straw(356 g/kg wet basis) after being treated with inoculants of different types of lactic acid bacteria(LAB). The treatments included the addition of no LAB additive(control),which was deionized water; homo-fermentative LAB alone(^(ho)LAB), which was Lactobacillus plantarum alone), and a mixture of homo-fermentative and hetero-fermentative LAB(^(he+ho)LAB), which were L. plantarum, Lactobacillus casei, and Lactobacillus buchneri. The results showed that the inoculation of the mixture of CSL and air-dried rice straw with ^(he+ho)LAB significantly increased the concentration of acetic acid and lactic acid compared with the control(P < 0.05). The addition of ^(he+ho)LAB effectively inhibited the growth of yeast in the silage. The concentration of total lactic acid bacteria in the ^(he+ho)LAB-treated silage was significant higher than those obtained in other groups(P < 0.05). The duration of the aerobic stability of the silages increased from 56 h to >372 h. The control group was the first to spoil, whereas the silage treated with ^(he+ho)LAB remained stable throughout the 372 h period of monitoring. The results demonstrated that the ^(he+ho)LAB could effectively improve the fermentation quality and aerobic stability of the silage. | Xinxin Li Wenbin Xu Jinshan Yang Hongbo Zhao Chunfang Pan Xue Ding Yonggen Zhang | 2016 | Animal Nutrition2016，，3： | 17 |
| 2 | High-resolution carbon isotope record for the Paleocene-Eocene thermal maximum from the Nanyang Basin,Central China显示文摘古新始新世的热最大值(PETM ) 是全球温暖的一个短暂事件,与发生在古新 / 始新世的边界的巨大的大气的温室气体输入联系了。Biostratigraphic 和同位素 stratigraphic 研究显示 PETM 事件很好在 Nanyang 盆在 Yuhuangding 节的泥土存款被记录,华中,与碳同位素,在 19-m-thick 泥土以内的锝 ?.1 鈥 ? 的否定旅行扔。这是到目前为止在世界上发现的 PETM 的最高的分辨率记录。PETM 事件在 2-cm-thick 泥土沉积以内被触发,与未 1 3C (稳定的碳同位素比率) 从的减少 ? 3.2 鈥 ? 到 ? 5.2 鈥吗?为是的一个短暂时期建议一个巨大的甲烷水合物版本可能由一个灾难的事件引起了。在海洋、陆上的记录之间的比较为 PETM 事件显示鈥淭h ree 阶段模型鈥 ? 。开始在未 1 3C 记录有一次快速的否定旅行,由一个慢慢地减少的趋势,然后渐渐的积极恢复列在后面,相应分别地到海洋的甲烷水合物的快速的分离,由甲烷然后释放甲烷的消费的一个慢版本列在后面。 | ZHU Min DINGZhongLi WANG Xu CHEN ZuoLing JIANG HanChao DONG XinXin JI JunLiang TANG ZiHua LUO Pan | 2010 | Chinese Science Bulletin2010，55，31： | 6 |
| 3 | The Security Analysis of Quantum SAGR04 Protocol in Collective-Rotation Noise Channel显示文摘Noise exists in the actual communication environment. It is necessary and significant to analyze the security of SAGR04 protocol in the noise environment. An excellent model of collective rotation noise analysis is introduced and the discussing of the security of SAGR04 protocol is based on the method of information theory. The eavesdropping can be detected for the increment of the qubit error rate and eavesdropper can maximally get about50% of the keys. It can be concluded that the SAGR04 protocol, used as quantum key distribution, is secure. | LI Jian PAN Zeshi ZHENG Jun SUN Fengqi YE Xinxin YUAN Kaiguo | 2015 | Chinese Journal of Electronics2015，24，4： | 6 |
| 4 | Suppressing by-product via stratified adsorption effect to assist highly reversible zinc anode in aqueous electrolyte显示文摘The development of promising zinc anodes mainly suffers from their low plating/stripping coulombic efficiencies when using aqueous electrolyte,which are mainly associated with the interfacial formation of irreversible by-products.It is urgent to develop technologies that can solve this issue fundamentally.Herein,we report an artificial Sc_(2)O_(3) protective film to construct a new class of interface for Zn anode.The density functional theory simulation and experimental results have proven that the interfacial side reaction was inhibited via a stratified adsorption effect between this artificial layer and Zn anode.Benefiting from this novel structure,the Sc_(2)O_(3)-coated Zn anode can run for more than 100 cycles without short circuit and exhibit low voltage hysteresis,and the coulombic efficiency increases by 1.2%.Importantly,it shows a good application prospect when matched with two of popular manganese-based and vanadium-based cathodes.The excellent electrochemical performance of the Sc_(2)O_(3)-coated Zn anode highlights the importance of rational design of anode materials and demonstrates a good way for developing high-performance Zn anodes with long lifespan and high efficiency. | Miao Zhou Shan Guo Guozhao Fang Hemeng Sun Xinxin Cao Jiang Zhou Anqiang Pan Shuquan Liang | 2021 | Journal of Energy Chemistry2021，30，4： | 6 |
| 5 | The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection显示文摘Epigenetic modifications to histones dictate the differentiation of naïve CD4^(+) T cells into different subsets of effector T helper(TH)cells.The histone methyltransferase enhancer of zeste homolog 2(EZH2)has been implicated in the mechanism regulating the differentiation of TH1,TH2 and regulatory T(Treg)cells.However,whether and how EZH2 regulates follicular helper T(TFH)cell differentiation remain unknown.Using a mouse model of acute lymphocytic choriomeningitis virus(LCMV)infection,we observed abundant EZH2 expression and associated H3K27me3 modifications preferentially in the early committed virus-specific TFH cells compared to those in TH1 cells.Ablation of EZH2 in LCMV-specific CD4^(+) T cells leads to a selective impairment of early TFH cell fate commitment,but not late TFH differentiation or memory TFH maintenance.Mechanistically,EZH2 specifically stabilizes the chromatin accessibility of a cluster of genes that are important for TFH fate commitment,particularly B cell lymphoma 6(Bcl6),and thus directs TFH cell commitment.Therefore,we identified the chromatin-modifying enzyme EZH2 as a novel regulator of early TFH differentiation during acute viral infection. | Xiangyu Chen Guoshuai Cao Jialin Wu Xinxin Wang Zhiwei Pan Jianbao Gao Qin Tian Lifan Xu Zhirong Li Yaxing Hao Qizhao Huang Pengcheng Wang Minglu Xiao Luoyingzi Xie Shupei Tang Zhenyu Liu Li Hu Jianfang Tang Ran He Li Wang Xinyuan Zhou Yuzhang Wu Mengjie Chen Beicheng Sun Bo Zhu Jun Huang Lilin Ye | 2020 | Cellular & Molecular Immunology2020，17，3： | 4 |
| 6 | Synchronous drying and cooling in central Asia duringlate Oligocene显示文摘Aridification of central Asia during late Oligocene and Early Miocene has been documented by numerous eolian records from the North Pacific and central Asia. However, direct evidence of aridity from the interior of the arid zone is still rather scarce. To better reconstruct the climate history in central Asia during the late Oligocene, we have analyzed ostracod assemblages and gypsum content in the sediments from the lacustrine Jingou River section in the northern Tianshan Mountains. Our results show that the cold water species Candona cf. Neglecta and Pseudocandona albicans replaced the warm water species Ilyocypris bradyi and Ilyocypris sp. to become the dominant species at 23.8 Ma, indicating significant cooling in central Asia at that time. At the same time, a substantial increase in gypsum content indicates the intensification of central Asian drying. The synchronous cooling and drying approximately coincided with the Oi2b.1 and/or Mi1 events, implying a causal linkage between late Oligocene global cooling and central Asian aridity. | DONG XinXin DING ZhongLi YANG ShiLing LUO Pan WANG Xu JI JunLiang | 2013 | Chinese Science Bulletin2013，58，25： | 3 |
| 7 | The mechanosensitive lncRNA Neat1 promotes osteoblast function through paraspeckle-dependent Smurf1 mRNA retention显示文摘Mechanical stimulation plays an important role in bone remodeling. Exercise-induced mechanical loading enhances bone strength,whereas mechanical unloading leads to bone loss. Increasing evidence has demonstrated that long noncoding RNAs(lnc RNAs) play key roles in diverse biological, physiological and pathological contexts. However, the roles of lnc RNAs in mechanotransduction and their relationships with bone formation remain unknown. In this study, we screened mechanosensing lnc RNAs in osteoblasts and identified Neat1, the most clearly decreased lnc RNA under simulated microgravity. Of note, not only Neat1 expression but also the specific paraspeckle structure formed by Neat1 was sensitive to different mechanical stimulations, which were closely associated with osteoblast function. Paraspeckles exhibited small punctate aggregates under simulated microgravity and elongated prolate or larger irregular structures under mechanical loading. Neat1 knockout mice displayed disrupted bone formation, impaired bone structure and strength, and reduced bone mass. Neat1 deficiency in osteoblasts reduced the response of osteoblasts to mechanical stimulation. In vivo, Neat1 knockout in mice weakened the bone phenotypes in response to mechanical loading and hindlimb unloading stimulation. Mechanistically, paraspeckles promoted nuclear retention of E3 ubiquitin ligase Smurf1 m RNA and downregulation of their translation, thus inhibiting ubiquitination-mediated degradation of the osteoblast master transcription factor Runx2, a Smurf1 target. Our study revealed that Neat1 plays an essential role in osteoblast function under mechanical stimulation, which provides a paradigm for the function of the lnc RNA-assembled structure in response to mechanical stimulation and offers a therapeutic strategy for long-term spaceflight-or bedrest-induced bone loss and age-related osteoporosis. | Caizhi Liu Xingcheng Gao Yuheng Li Weijia Sun Youjia Xu Yingjun Tan Ruikai Du Guohui Zhong Dingsheng Zhao Zizhong Liu Xiaoyan Jin Yinlong Zhao Yinbo Wang Xinxin Yuan Junjie Pan Guodong Yuan Youyou Li Wenjuan Xing Guanghan Kan Yanqing Wang Qi Li Xuan Han Jianwei Li Shukuan Ling Yingxian Li | 2022 | Bone Research2022，10，2： | 3 |
| 8 | Tuning crystal structure and redox potential of NASICON-type cathodes for sodium-ion batteries显示文摘Sodium superionic conductor(NASICON)-type compounds have been regarded as promising cathodes for sodium-ion batteries(SIBs)due to their favorable ionic conductivity and robust structural stability.However,their high cost and relatively low energy density restrict their further practical application,which can be tailored by widening the operating voltages with earth-abundant elements such as Mn.Here,we propose a rational strategy of infusing Mn element in NASICON frameworks with sufficiently mobile sodium ions that enhances the redox voltage and ionic migration activity.The optimized structure of Na3.5Mn0.5V1.5(PO4)3/C is achieved and investigated systematically to be a durable cathode(76.6%capacity retention over 5,000 cycles at 20 C)for SIBs,which exhibits high reversible capacity(113.1 mAh·g^−1 at 0.5 C)with relatively low volume change(7.6%).Importantly,its high-areal-loading and temperature-resistant sodium ion storage properties are evaluated,and the full-cell configuration is demonstrated.This work indicates that this Na3.5Mn0.5V1.5(PO4)3/C composite could be a promising cathode candidate for SIBs. | Xuemei Ma Xinxin Cao Yifan Zhou Shan Guo Xiaodong Shi Guozhao Fang Anqiang Pan Bingan Lu Jiang Zhou Shuquan Liang | 2020 | Nano Research2020，13，12： | 2 |
| 9 | Paclitaxel-induced stress granules increase LINE-1 mRNA stability to promote drug resistance in breast cancer cells显示文摘Abnormal expression of long interspersed element-1(LINE-1)has been implicated in drug resistance,while our previous study showed that chemotherapy drug paclitaxel(PTX)increased LINE-1 level with unknown mechanism.Bioinformatics analysis suggested the regulation of LINE-1 mRNA by drug-induced stress granules(SGs).This study aimed to explore whether and how SGs are involved in drug-induced LINE-1 increase and thereby promotes drug resistance of triple negative breast cancer(TNBC)cells.We demonstrated that SGs increased LINE-1 expression by recruiting and stabilizing LINE-1 mRNA under drug stress,thereby adapting TNBC cells to chemotherapy drugs.Moreover,LINE-1 inhibitor efavirenz(EFV)could inhibit drug-induced SG to destabilize LINE-1.Our study provides the first evidence of the regulation of LINE-1 by SGs that could be an important survival mechanism for cancer cells exposed to chemotherapy drugs.The findings provide a useful clue for developing new chemotherapeutic strategies against TNBCs. | Xiao Shi Xinxin Si Ershao Zhang Ruochen Zang Nan Yang He Cheng Zhihong Zhang Beijing Pan Yujie Sun | 2021 | The Journal of Biomedical Research2021，35，6： | 1 |
| 10 | Research on the Evaluation System of Epoxy Asphalt Steel Deck Pavement Distress Condition显示文摘Epoxy asphalt concrete has been one of the mainstream technology of steel deck pavement in China. But little specification about evaluation system for its distress condition has been researched and maintenance was still unsystematic. The section weight coefficient of different distress is proposed by analyzing the applicability of the “Highway Performance Assessment Standards”. Indexes mainly including SDPCI PDR and PCR are presented to evaluate its distress condition. The evaluation system and maintenance plan decision tree were recommended which can assist scientific maintenance of epoxy asphalt steel deck pavement. | Hui Zhang Yingtao Li Xinxin Fu Youqiang Pan | 2019 | Journal of Harbin Institute of Technology(New Series)2019，26，5： | 1 |
| 11 | Preparation of a dispersible PEGylate nanostructured lipid carriers (NLC) loaded with 10-hydroxycamptothecin by spray-drying显示文摘 | Zhang Xinxin Pan Weisan Gan Li | 2008 | Chemical & Pharmaceutical Bulletin2008，56，12： | 1 |
| 12 | Identification and expression analysis of Tubulin gene family in upland cotton显示文摘Background:Cott on fibers are single-celled exte nsions of the seed epidermis,a model tissue for studying cytoskeleton.Tubulin genes play a critical role in synthesizing the microtubules(MT)as a core element of the cytoskeleton.However,there is a lack of studies concerning the systematic characterization of the tubulin gene family in cotton.Therefore,the identification and portrayal of G.hirsutum tubulin genes can provide key targets for molecular manipulation in cotton breeding.Result:In this study,we investigated all tubulin genes from different plant species and identified 98 tubulin genes in G.hirsutum.Phylogenetic an a lysis showed that tubulin family genes were classified into three subfamilies.The protein motifs and gene structure ofβ-tubulin genes are more conserved compared withγ-tubulin genes.Most tubulin genes are located at the proximate ends of the chromosomes.Spatiotemporal expression pattern by transcriptome and qRT-PCR analysis revealed that 12α-tubulin andβ-tubulin genes are specifically expressed during different fiber development stages.However,Gh.A03G027200,Gh.D03G 169300,and Gh.A1lG258900 had differential expression patterns at distinct stages of fiber development in varieties JO2508 and ZRI015.Conclusion:In this study,the evol ut io nary an alysis showed that the tubulin genes were divided into three clades.The genetic structures and molecular functions were highly con served in different plants.Three candidate genes,Gh.A03G027200f Gh.D03G169300,and Gh.A11G258900 may play a key role during fiber development complementing fiber length and strength. | CHEN Baojun ZHAO Junjie FU Guoyong PEI Xinxin PAN Zhao'e LI Hongge AHMED Haris HE Shoupu DU Xiongming | 2021 | Journal of Cotton Research2021，4，3： | 1 |
| 13 | Transjugular intrahepatic portosystemic shunt induced short- and long-term cerebral blood flow variations in cirrhotic patients: an arterial spin labeling MRI study显示文摘 | Gang Zheng Long Jiang Zhang Yue Cao Zhiying Pan Rong Feng Qi Ling Ni Donghong Shi Xinxin Fan Guang Ming Lu | 2013 | Metabolic Brain Disease2013，，3： | 1 |
| 14 | Enzymatic synthesizing o3 phytosterol oleic esters 显示文摘 | Pan Xinxin Chen Biqiang Wang Juan | 2012 | Applied Biochemistry and Biotecimology2012，168，： | 1 |
| 15 | Tuning Interface Bridging Between MoSe2 and Three‑Dimensional Carbon Framework by Incorporation of MoC Intermediate to Boost Lithium Storage Capability显示文摘Interface engineering has been widely explored to improve the electrochemical performances of composite electrodes,which governs the interface charge transfer,electron transportation,and structural stability.Herein,MoC is incorporated into MoSe2/C composite as an intermediate phase to alter the bridging between MoSe2-and nitrogen-doped three-dimensional(3D)carbon framework as MoSe2/MoC/N–C connection,which greatly improve the structural stability,electronic conductivity,and interfacial charge transfer.Moreover,the incorporation of MoC into the composites inhibits the overgrowth of MoSe2 nanosheets on the 3D carbon framework,producing much smaller MoSe2 nanodots.The obtained MoSe2 nanodots with fewer layers,rich edge sites,and heteroatom doping ensure the good kinetics to promote pseudo-capacitance contributions.Employing as anode material for lithium-ion batteries,it shows ultralong cycle life(with 90%capacity retention after 5000 cycles at 2 A g−1)and excellent rate capability.Moreover,the constructed LiFePO4//MoSe2/MoC/N–C full cell exhibits over 86%capacity retention at 2 A g−1 after 300 cycles.The results demonstrate the effectiveness of the interface engineering by incorporation of MoC as interface bridging intermediate to boost the lithium storage capability,which can be extended as a potential general strategy for the interface engineering of composite materials. | Jing Chen Yilin Luo Wenchao Zhang Yu Qiao Xinxin Cao Xuefang Xie Haoshen Zhou Anqiang Pan Shuquan Liang | 2020 | Nano-Micro Letters2020，12，12： | 1 |
| 16 | Enzy- matic synthesizing of phytosterol oleic esters 显示文摘 | PAN Xinxin CHEN Biqiang WANG Juan | 2012 | Appl Biochem Biotechnol2012，168，： | 1 |
| 17 | Scission of C–O and C–C linkages in lignin over RuRe alloy catalyst显示文摘The performance of lignin depolymerization is basically determined by the interunit C–O and C–C bonds.Numerous C–O bond cleavage strategies have been developed, while the cleavage of C–C bond between the primary aromatic units remains a challenging task due to the high dissociation energy of C–C bond.Herein, a multifunctional Ru Re alloy catalyst was designed, which exhibited exceptional catalytic activity for the cleavage of both C–O and C–C linkages in a broad range of lignin model compounds(β-1, a-5, 5–5,β-O-4, 4-O-5) and two stubborn lignins(kraft lignin and alkaline lignin), affording 97.5% overall yield of monocyclic compounds from model compounds and up to 129% of the maximum theoretical yield of monocyclic products based on C–O bonds cleavage from realistic lignin. Scanning transmission electron microscopy(STEM) characterization showed that Ru Re(1:1) alloy particles with hexagonal close-packed structure were homogeneously dispersed on the support. Quasi-in situ X-ray photoelectron spectroscopy(XPS), and X-ray absorption spectroscopy(XAS) indicate that Ru species were predominantly metallic state, whereas Re species were partially oxidized;meanwhile, there was a strong interaction between Ru and Re, where the electron transfer from Re to Ru was occurred, resulting in great improvement on the capability of C–O and C–C bonds cleavage in lignin conversion. | Xinxin Li Yangming Ding Xiaoli Pan Yanan Xing Bo Zhang Xiaoyan Liu Yuanlong Tan Hua Wang Changzhi Li | 2022 | Journal of Energy Chemistry2022，31，4： | 1 |
| 18 | Effects of allitridi on in-tracellular Ca 2+concentration in isolated rat brain cells显示文摘 | MA Xiaohong PAN Xinxin LIU Tianpei | 1999 | Acta Pharmacol Sin1999，20，7： | 1 |
| 19 | Preparation of Novel Core-shell Non-sintered Lightweight Aggregate and Its Application in Wallboard for Better Properties显示文摘Due to the relatively high density of conventional non-sintered lightweight aggregate(NLA),a low-density core-shell NLA(CNLA) was developed.Moreover,two types of porous lightweight aggregate concrete (PLAC) for wallboard were designed,using both foam and lightweight aggregates.The effects of LA on lightweight concrete workability,compressive strength,dry shrinkage,and thermal conductivity were studied and compared.The bulk density of CNLA can be lowered to 500 kg/m^(3),and its cylinder crushing strength is 1.6 MPa.PLACs also have compressive strengths ranging from 7.8 to 11.8 MPa,as well as thermal conductivity coefficients ranging from 0.193 to 0.219 W/(m·K^(-1)).The CNLA bonds better to the paste matrix at the interface transition zone,and CNLA concrete has a superior pore structure than SLA concrete,resulting in a 20% improvement in fluidity,a 10% increase in strength,a 6% reduction in heat conductivity,and an 11% decrease in drying shrinkage. | 庞超明 ZHANG Chunpeng MENG Xinxin PAN Jinlong | 2022 | Journal of Wuhan University of Technology(Materials Science)2022，37，5： | 1 |
| 20 | Protective effects of berberine on neuronal injury in cultured cortical neurons in rats显示文摘 | Wu Junfang Wang Yan Pan Xinxin | 1999 | Acta Universitatis Medicinalis NanJing1999，，3： | 1 |
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