|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Does Helicobacter pylori eradication therapy for peptic ulcer prevent gastric cancer?显示文摘AIM:To investigate the effects of Helicobacter pylori (H pylori)eradication therapy for treatment of peptic ulcer on the incidence of gastric cancer. METHODS:A multicenter prospective cohort study was conducted between November 2000 and December 2007 in Yamagata Prefecture,Japan.The study included patients with H pylori-positive peptic ulcer who decided themselves whether to receive H pylori eradication(eradication group)or conventional antacid therapy(non-eradication group).Incidence of gastric cancer in the two groups was determined based on the results of annual endoscopy and questionnaire surveys,as well as Yamagata Prefectural Cancer Registry data,and was compared between the two groups and by results of H pylori therapy.RESULTS:A total of 4133 patients aged between 13 and 91 years(mean 52.9 years)were registered,and 56 cases of gastric cancer were identified over a mean follow-up of 5.6 years.The sex-and age-adjusted incidence ratio of gastric cancer in the eradication group, as compared with the non-eradication group,was 0.58 (95%CI:0.28-1.19)and ratios by follow-up period(<1 year,1-3 years,>3 years)were 1.16(0.27-5.00),0.50 (0.17-1.49),and 0.34(0.09-1.28),respectively.Longer follow-up tended to be associated with better prevention of gastric cancer,although not to a significant extent.No significant difference in incidence of gastric cancer was observed between patients with successful eradication therapy(32/2451 patients,1.31%)and those with treatment failure(11/639 patients,1.72%).Among patients with duodenal ulcer,which is known to be more prevalent in younger individuals,the incidence of gastric cancer was significantly less in those with successful eradication therapy(2/845 patients,0.24%)than in those with treatment failure(3/216 patients,1.39%). CONCLUSION:H pylori eradication therapy for peptic ulcer patients with a mean age of 52.9 years at registration did not significantly decrease the incidence of gastric cancer. | Katsuhiro Mabe Mikako Takahashi Haruhumi Oizumi Hideaki Tsukuma Akiko Shibata Kazutoshi Fukase Toru Matsuda Hiroaki Takeda Sumio Kawata | 2009 | World Journal of Gastroenterology2009，15，34： | 10 |
| 2 | Survival of geriatric patients after percutaneous endoscopic gastrostomy in Japan显示文摘AIM: To examine the long term survival of geriatric patients treated with percutaneous endoscopic gastrostomy (PEG) in Japan. METHODS: We retrospectively included 46 Japanese community and tertiary hospitals to investigate 931 consecutive geriatric patients (≥ 65 years old) with swallowing difficulty and newly performed PEG between Jan 1st 2005 and Dec 31st 2008. We set death as an outcome and explored the associations among patient’s characteristics at PEG using log-rank tests and Cox proportional hazard models. RESULTS: Nine hundred and thirty one patients were followed up for a median of 468 d. A total of 502 deaths were observed (mortality 53%). However, 99%, 95%, 88%, 75% and 66% of 931 patients survived more than 7, 30, 60 d, a half year and one year, respectively. In addition, 50% and 25% of the patients survived 753 and 1647 d, respectively. Eight deaths were considered as PEG-related, and were associated with lower serum albumin levels (P = 0.002). On the other hand, among 28 surviving patients (6.5%), PEG was removed. In a multivariate hazard model, older age [hazard ratio (HR), 1.02; 95% confidence interval (CI), 1.00-1.03; P = 0.009], higher C-reactive protein (HR, 1.04; 95% CI: 1.01-1.07; P = 0.005), and higher blood urea nitrogen (HR, 1.01; 95% CI: 1.00-1.02; P = 0.003) were significant poor prognostic factors, whereas higher albumin (HR, 0.67; 95% CI: 0.52-0.85; P = 0.001), female gender (HR, 0.60; 95% CI: 0.48-0.75; P < 0.001) and no previous history of ischemic heart disease (HR, 0.69; 95% CI: 0.54-0.88, P = 0.003) were markedly better prognostic factors. CONCLUSION: These results suggest that more than half of geriatric patients with PEG may survive longer than 2 years. The analysis elucidated prognostic factors. | Yutaka Suzuki Seryna Tamez Akihiko Murakami Akihiko Taira Akihiro Mizuhara Akira Horiuchi Chie Mihara Eiji Ako Hirohito Muramatsu Hitoshi Okano Hitoshi Suenaga Kazuaki Jomoto Junya Kobayashi Katsunari Takifuji Kazuhiro Akiyama Koh Tahara Koji Onishi Makoto Shimazaki Masami Matsumoto Masashi Ijima Masato Murakami Masato Nakahori Michiaki Kudo Michio Maruyama Mikako Takahashi Naohiro Washizawa Shigeru Onozawa Satoshi Goshi Satoyoshi Yamashita Shigeki Ono Shin Imazato Shinji Nishiwaki Shuichirou Kitahara Takao Endo Takao Iiri Takeshi Nagahama Takuto Hikichi Tatsuya Mikami Tetsuo Yamamoto Tetsushi Ogawa Tomoko Ogawa Tomoyuki Ohta Toshifumi Matsumoto Toshiroh Kura Tsutomu Kikuchi Tsuyoshi Iwase Tsuyotoshi Tsuji Yukio Nishiguchi Mitsuyoshi Urashima | 2010 | World Journal of Gastroenterology2010，16，40： | 4 |
| 3 | Distal movement of mandibular molars in adult patients with the skeletal anchorage system显示文摘 | Junji Sugawara Takayoshi Daimaruya Mikako Umemori Hiroshi Nagasaka Ichiro Takahashi Hiroshi Kawamura Hideo Mitani | 2003 | American Journal of Orthodontics & Dentofacial Orthopedics2003，，2： | 2 |
| 4 | Diagnosis and Evaluation of Nonalcoholic Fatty Liver Disease显示文摘 | Mikako Obika Hirofumi Noguchi Amalia Gastaldelli | 2011 | Experimental Diabetes Research2011，，： | 2 |
| 5 | Effect of Sevelamer and Calcium-Based Phosphate Binders on Coronary Artery Calcification and Accumulation of Circulating Advanced Glycation End Products in Hemodialysis Patients显示文摘 | Takatoshi Kakuta Reika Tanaka Toru Hyodo Hajime Suzuki Genta Kanai Mikako Nagaoka Hiroo Takahashi Nobuhito Hirawa Yoichi Oogushi Toshio Miyata Hiroyuki Kobayashi Masafumi Fukagawa Akira Saito | 2011 | American Journal of Kidney Diseases2011，，3： | 2 |
| 6 | Histological and histomorphometrical changes in rat alveolar bone following antagonistic tooth extraction and/or ovariectomy显示文摘 | Sadakazu Ejiri Eiichi Toyooka Mikako Tanaka | 2006 | Archives of Oral Biology2006，51，： | 1 |
| 7 | ^18F-FDG accumulation in atherosclerotic plaques: immunohistochemical and PET imaging study显示文摘 | OGAWA MIKAKO | 2004 | J Nucl Med2004，45，： | 1 |
| 8 | Fracture Resistance of Pulpless Teeth Restored with Post cores and Crowns显示文摘 | Mikako Hayashi Yutaka Takahashi Satoshi Imazato | 2006 | Dental Materials2006，22，5： | 1 |
| 9 | Inhibitory effect of phosphorylated oligosaccharides prepared from potato starch on the formation of calcium phosphate显示文摘 | Hiroshi Kamasaka Mikako Uchida Kaname Kusaka | 1995 | Biosci Biotech Biochem1995，59，8： | 1 |
| 10 | Serum resistin (FIZZ3) protein is increased in obese humans 显示文摘 | Mikako D Y Jason E | 2003 | J Clin Endocrinol Metab2003，88，11： | 1 |
| 11 | Topical application of anti-angiogenic peptides based on pigment epithelium-derived factor can improve psoriasis显示文摘 | Riichiro Abe Sho-ichi Yamagishi Yasuyuki Fujita Daichi Hoshina Mikako Sasaki Kazuo Nakamura Takanori Matsui Tadamichi Shimizu Richard Bucala Hiroshi Shimizu | 2009 | Journal of Dermatological Science2009，，3： | 1 |
| 12 | Maternal molecular hydrogen administration ameliorates rat fetal hippocampal damage byin uterois- chemia - reperfusion 显示文摘 | Yukio M Tomomi K Mikako I | 2014 | Free Radical Biology and Medicine2014，69，： | 1 |
| 13 | LIF/STAT3/SOCS3 Signaling Pathway in Murine Bone Marrow Stromal Cells Suppresses Osteoblast Differentiation显示文摘 | Kenta Matsushita Shousaku Itoh Shun Ikeda Yumiko Yamamoto Yukako Yamauchi Mikako Hayashi | 2014 | J Cell Biochem2014，，7： | 1 |
| 14 | Open-label trial and randomized, doub- le-blind, plaeebo-eontrolled, crossover trial of hydrogen-enriched water for mitoehondrial and inflammatory myopathies 显示文摘 | Mikako I Tohru I Ko S | 2011 | Medieal Gas Re- search2011，1，1： | 1 |
| 15 | Hepatitis C virus genotype distribution in Myanmar: Predominance of genotype 6 and existence of new genotype 6 subtype显示文摘 | Aye Aye Lwin Toshiyuki Shinji Myo Khin Ne Win Mikako Obika Shigeru Okada Norio Koide | 2007 | Hepatology Research2007，，5： | 1 |
| 16 | Birth of a healthy baby following bitrification of human blastocysts显示文摘 | Yoshimasa Y Setsuko S Mikako Y | 2001 | FertilSteril2001，75，5： | 1 |
| 17 | Interaction between interleukin-1β ?31T/C gene polymorphism and drinking and smoking habits on the risk of hepatocellular carcinoma among Japanese显示文摘 | Tatsuhiko Sakamoto Yasuki Higaki Megumi Hara Masayoshi Ichiba Mikako Horita Toshihiko Mizuta Yuichiro Eguchi Tsutomu Yasutake Iwata Ozaki Kyosuke Yamamoto Shingo Onohara Seiji Kawazoe Hirohisa Shigematsu Shunzo Koizumi Keitaro Tanaka | 2008 | Cancer Letters2008，，1： | 1 |
| 18 | Significance of three step prescription checking by pharmacists显示文摘In many hospitals,prescription checks are conducted by 2 or 3 individual pharmacists at each step of prescription checking,dispensing,and final checking to maintain the safety and efficacy of pharmaceutical therapies in Japan[1,2].In Gunma University Hospital,we also check all prescriptions by 3 pharmacists at each step of dispensing(3 step prescription check system)with the exception of night time.In this study,to assess the significance of our 3 step prescription check system for managing safety of pharmaceutical therapies,we investigated prescriptions that needed the confirmation of questionable points and prescription corrections. | Mikako Shimone Daisuke Nagano Asami Matsushita Junko Tsukamoto Yu Yanai Akiko Kaneta Kyoko Obayashi Takuya Araki Koujirou Yamamoto | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，1： | 1 |
| 19 | Inhibitory Effect of Phosphorylated Oligosaccharides Prepared from Potato Starch on the Formation of Calcium Phosphate显示文摘 | Hiroshi Kamasaka Mikako Uchida Kaname Kusaka | 1995 | Biosci Biotech Biochem1995，59，8： | 1 |
| 20 | Detection of Rabies Virus RNA Isolated from Several Species of Animals in Brazil by RT-PCR 显示文摘 | Mikako ITO Takuya ITOU Takeo SAKAI | 2002 | J Vet Med Sci2002，63，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员