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| 1 | 乳腺癌组织中TP和TS及DPD mRNA表达与预后的关系显示文摘目的 探讨乳腺癌组织中胸苷酸化酶 (TP)、胸苷酸合成酶 (TS)和二氢嘧啶脱氢酶(DPD)mRNA表达水平及其与预后的关系。方法 采用real time定量PCR技术检测经过微选的 9例正常乳腺组织和 86例乳腺癌组织TP、TS和DPD的mRNA表达水平。结果 肿瘤组织中TP、TS和DPDmRNA表达水平中位数分别为 16 .5 4 ,0 .38和 2 .74 ,正常乳腺组织分别为 11.75 ,0 .2 5和 8.33,差异均无显著性 (P >0 .0 5 )。除年龄与DPD表达呈负相关外 ,TP、TS和DPDmRNA表达与肿瘤体积、淋巴结转移、组织学分级、临床分期均无相关性。TP、DPD高表达组和低表达组之间 ,无瘤生存期和总生存期差异均无显著性。TS高表达组和低表达组无瘤生存期差异无显著性 (P =0 .0 6 9) ;平均总生存期分别为 5 9.0 0和 70 .30个月 ,差异有显著性 (P =0 .0 4 96 )。结论 仅检测TSmRNA对判断乳腺癌预后有参考价值 ,同时检测TP、TS和DPD具有更好的预测价值。 | 李惠翔 Suo ZH 张云汉 Bjrn Risberg Mats G Karlsson Jahn M Nesland | 2004 | 中华肿瘤杂志2004，26，11： | 9 |
| 2 | Mapping aboveground biomass and its prediction uncertainty using LiDAR and field data, accounting for tree-level allometric and LiDAR model errors显示文摘Background: The increasing availability of remotely sensed data has recently challenged the traditional way of performing forest inventories, and induced an interest in model-based inference. Like traditional design-based inference, model-based inference allows for regional estimates of totals and means, but in addition for wall-to-wall mapping of forest characteristics. Recently Light Detection and Ranging(LiDAR)-based maps of forest attributes have been developed in many countries and been well received by users due to their accurate spatial representation of forest resources. However, the correspondence between such mapping and model-based inference is seldom appreciated. In this study we applied hierarchical model-based inference to produce aboveground biomass maps as well as maps of the corresponding prediction uncertainties with the same spatial resolution. Further, an estimator of mean biomass at regional level, and its uncertainty, was developed to demonstrate how mapping and regional level assessment can be combined within the framework of model-based inference.Results: Through a new version of hierarchical model-based estimation, allowing models to be nonlinear, we accounted for uncertainties in both the individual tree-level biomass models and the models linking plot level biomass predictions with LiDAR metrics. In a 5005 km2 large study area in south-central Sweden the predicted aboveground biomass at the level of 18 m×18 m map units was found to range between 9 and 447 Mg·ha^-1. The corresponding root mean square errors ranged between 10 and 162 Mg·ha^-1. For the entire study region, the mean aboveground biomass was 55 Mg·ha^-1 and the corresponding relative root mean square error 8%. At this level 75%of the mean square error was due to the uncertainty associated with tree-level models.Conclusions: Through the proposed method it is possible to link mapping and estimation within the framework of model-based inference. Uncertainties in both tree-level biomass models and models linking plot level biomass with LiDAR data are accounted for, both for the uncertainty maps and the overall estimates. The development of hierarchical model-based inference to handle nonlinear models was an important prerequisite for the study. | Svetlana Saarela AndréWästlund Emma Holmström Alex Appiah Mensah Sören Holm Mats Nilsson Jonas Fridman Göran Ståhl | 2020 | Forest Ecosystems2020，7，3： | 3 |
| 3 | Dependence of stimulated Brillouin scattering in multimode fibers on beam quality,pulse duration,and coherence length显示文摘 | Lopez Q M Sheila G Sverker H | 2003 | Journal of Optical Society of America B2003，20，3： | 1 |
| 4 | Lubricant replenishment in rolling bearing contacts显示文摘 | Leonid G Mats G L Piet M L | 2008 | STLE Trans2008，51，： | 1 |
| 5 | Stabilization of chaos by proportional pulses in the system variables 显示文摘 | G UE MEZ J | 1994 | Phys Rev Lett1994，72，： | 1 |
| 6 | The first clinical uterus transplantation trial: a six-month report显示文摘 | Mats Br?nnstr?m Liza Johannesson Pernilla Dahm-K?hler Anders Enskog Johan M?lne Niclas Kvarnstr?m Cesar Diaz-Garcia Ash Hanafy Cecilia Lundmark Janusz Marcickiewicz Markus G?bel Klaus Groth Randa Akouri Saskia Eklind Jan Holgersson Andreas Tzakis Michael | 2014 | Fertility and Sterility2014，，： | 1 |
| 7 | Portaccess minimally invasive surgery for atrial septal defects: a 10 year single center experienee in 166 patients显示文摘 | VISTARINI N AIEILO M MAT'FIUCCI G | 2010 | J Thorac Cardiovasc Surg2010，139，1： | 1 |
| 8 | Efficacy and safety of on-pump beating heart surgery for valvular disease显示文摘 | Mat sumoto Y Wat anabe G Endo M | 2002 | Am Thorac Surg2002，74，3： | 1 |
| 9 | Application of the sulphide capacity concept on high-basicity ladle slags used in bearing-steel production显示文摘 | Andersson MAT Jonsson P G Hallberg M | 1999 | ISIJ International1999，39，11： | 1 |
| 10 | Allergenicity of refined vegetable oils显示文摘 | CREVEL R W R KERKHOFF MAT KONING M M G | 2000 | Food and ChemicalToxicology2000，38，4： | 1 |
| 11 | Aliphatic polycarbonate resins for radi- ation curable powder coatings显示文摘 | PETER L i3 WENHIELM DANIEL NYSTR G M MATS JOHANSSON | 2005 | Progress in Organic Coat- ings2005，54，4： | 1 |
| 12 | De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus 显示文摘 | Luo G Hamatake R K Mat his D M | 2000 | J Virol2000，74，2： | 1 |
| 13 | Implementation and use of collaborative product development systems 显示文摘 | CHRISTINA C MATS G M MARIE B Z | 2006 | International Journal of Management and Decision Making2006，7，6： | 1 |
| 14 | Application of the sulphide capacity concept on high-basic-ity ladle slags used in bearing-steel production显示文摘 | ANDERSSON MAT JONSSON P G HALLBERG M | 1999 | ISU In-ternational1999，39，11： | 1 |
| 15 | Atomic-scale friction of a tungsten tip on a graphite surface 显示文摘 | Mat C M Mcclelland G M Erlandsson R | 1987 | Physical Review Letters1987，59，17： | 1 |
| 16 | ECM regulates MT1-MMP localization with betal or alphavbeta3 integrins at distinct cell compartments modulating its internalization and activity an human endothelial cells显示文摘 | Gálvez B G Matías-Román S Yá(n)ez-MóM | 2002 | J Cell Bio2002，159，3： | 1 |
| 17 | Micropatterned Polymer Films by Vapor-Induced Phase Separation Using Permeable Molds显示文摘 | Mat?′as B Ineke G M P Rob G H | 2009 | Adv Mater2009，12，28： | 1 |
| 18 | Improved microhardness and wear resistance of the as-deposited electroless Ni- P coating 显示文摘 | YAN M YING H G MAT Y | 2008 | Surface and Coatings Technology2008，202，24： | 1 |
| 19 | Aquaporin-4 deletion in mice reduces brain edema after acute water toxication and ischemic stroke显示文摘 | Manley G T Fujimura M MaT | 2000 | Nat Med2000，6，2： | 1 |
| 20 | Chem-ically activated kaolinites after de-intercalation of for-mamide显示文摘 | Val6§kov6 M Martynkovd G S Mat^jka V | 2007 | Ceramics2007，51，1： | 1 |
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