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| 1 | 丹参及其提取物拮抗P选择素的实验研究显示文摘为从中药中筛选选择素拮抗剂,连接P选择素或E选择素细胞膜外片段与小鼠IgG2bFc片段形成重组基因,并用昆虫细胞株表达、制备重组蛋白,用重组选择素与其靶细胞的黏附特性构建拮抗剂实验模型。结果表明,丹参注射液25mg/ml可以阻断95%以上靶细胞与P选择素的黏附;丹参酮IIA磺酸钠10μg/ml拮抗作用大于85%;总丹酚酸16μg/ml拮抗作用接近95%。丹参及其提取物对E选择素没有拮抗作用。结论:丹参及其提取物的作用位点在于P选择素,可能成为临床有效的选择素拮抗剂。 | 刘纪宁 徐波 Jan Holgersson | 2006 | 沈阳部队医药2006，19，1： | 6 |
| 2 | Expression of a human alpha-1,3/4-fucosyltransferase in the pit cell lineage of FVB/N mouse stomach results in production of Leb-containing glycoconjugates:a potential transgenic mouse model for studying Helicobacter pylori infection显示文摘 | Falk PG Bry L Holgersson J | 1995 | Proc Natl Acad Sci USA1995，92，5： | 1 |
| 3 | Identification of the nonclassical HLA molecules, mica, as targets for humoral immunity asmciated with irreversible rejection of kidney allografts显示文摘 | Sumitran-Holgerason S Wilczek H E Holgersson J | 2002 | Transplantation2002，74，2： | 1 |
| 4 | Sequelae from clavicular fractures are common:a prospective study of 222 patients显示文摘 | Nowak J Holgersson M Larsson S | 2005 | Acta Orthop2005，76，： | 1 |
| 5 | Expression of DNA damage response proteins and complete remission after radiotherapy of stage IB- IIA of cervical cancer显示文摘 | Beskow C Kanter L Holgersson A | 2006 | Br J Cancer2006，94，11： | 1 |
| 6 | Interleukin 46 afects cell death escaping mechanisms acting on Bax-Ku70 clusterin interaetionsin human colon cancer progression显示文摘 | Pucci S Skikuniene J Holgersson A | 2009 | Cell Cycle2009，8，3： | 1 |
| 7 | HLA-specific alloantibodies and renal graft outcome显示文摘 | Sumitarr Holgersson S | 2001 | Nephrol Dial Transplant2001，16，： | 1 |
| 8 | Radioresistant cervical cancer shows upregulation of the NHEJ pro- teins DNA-PKcs, Ku70 and Ku86 显示文摘 | Beskow C Skikuniene J Holgersson A | 2009 | Br J Cancer2009，101，5： | 1 |
| 9 | Radioresistant cer- vical cancer shows upregulation of the NHEJ proteins DNA- PKcs,Ku70 andKu86显示文摘 | Beskow C Skikuniene J Holgersson A | 2009 | BrJCancer2009，101，5： | 1 |
| 10 | Expression of a human alpha1,3/4-fucosyltransferase in the pit cell lineage of FVB/N mouse stomach results in production of Leb-containing glycoconjugateds:a potential transgenic mouse model for studying Helicobacter pylori infection显示文摘 | Falk PG Bry L Holgersson J | 1995 | Proc Natl Acad Sci USA 1995Feb 281995，92，5： | 1 |
| 11 | Radioresistant cervi- cal cancer shows upregulation of the NHEJ proteins DNA - PKcs, KuT0 and Ku86显示文摘 | Beskow C Skikuniene J Holgersson A | 2009 | Br J Cancer2009，101，5： | 1 |
| 12 | A prospective comparison between external fixation and plates for treatment of midshaft nonunions of the clavicle显示文摘 | Nowak J Rahme H Holgersson M | 2001 | Ann Chir Gynaecol2001，90，： | 1 |
| 13 | 查看详情显示文摘 | HeZ She R Sumitran Holgersson S | | 0，，： | 1 |
| 14 | Identification of the nonclassical HLA molecules,mica,as targets for humoral immunity associated with irreversible rejection of kidney allografts显示文摘 | SUMITRAN HOLGERSSON S WILCZEK H E HOLGERSSON J | 2002 | Transplantation2002，74，2： | 1 |
| 15 | The value of induction chemotherapy for survival in patients with non-small cell lung cancer treated with radiotherapy显示文摘 | Holgersson G Sandelin M Hoye E | 2012 | Anticancer Research2012，32，： | 1 |
| 16 | Swedish lung cancer radiation study group: the prognostic value of anaemia, thrombocytosis and leukocytosis at time of diagnosis in patients with non-small cell lung cancer 显示文摘 | Holgersson G Sandelin M Hoye E | 2012 | Med Oncol2012，29，5： | 1 |
| 17 | Radioresistant cervical cancer shows upregulation of the NHEJ proteins DNA-PKcs, Ku70 and Ku86 显示文摘 | Beskow C Skikuniene J Holgersson A | 2009 | Br J Cancer2009，101，： | 1 |
| 18 | Direct binding of purified HLA class I antigens by soluble NKG2/CD94 C-type lectins from natural killer cells显示文摘 | Ding Y Surnitran S Holgersson J | 1999 | Scand J lmmunol1999，49，5： | 1 |
| 19 | Radioresistant cervical cancer shows upregulation of the NHEJ proteins DNA-PKcs,Ku70 and Ku86显示文摘 | Beskow C Skikuniene J Holgersson A | 2009 | Br J Cancer2009，101，5： | 1 |
| 20 | Radioresistant cervi- cal cancer shows upregulation of the NHEJ proteins DNA-PKcs, Ku70 and Ku86显示文摘 | Beskow C Skikuniene J Holgersson A | 2009 | Br J Cancer2009，101，5： | 1 |
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