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3篇 您的检索式:作者名="Lars P.Bechmann"
    题名 作者 年代 出处 被引量
1Apoptosis versus necrosis rate as a predictor in acute liver failure following acetaminophen intoxication compared with acute‐on‐chronic liver failure显示文摘Lars P.Bechmann GuidoMarquitan ChristophJochum FuatSaner GuidoGerken AliCanbay 2007Liver International2007,,5:1
2Low‐molecular‐weight heparin in patients with advanced cirrhosis显示文摘Lars P.Bechmann MatthiasSichau MarcWichert GuidoGerken KnutKr?ger PhilipHilgard 2010Liver International2010,,1:1
3Evaluation and impact of different biomarkers for early detection of hepatocellular carcinoma显示文摘Worldwide,hepatocellular carcinoma(HCC)is a frequent complication of liver diseases and remains a major cause of cancer-related mortality.In addition,the prevalence of nonalcoholic steatohepatitis(NASH)as prerequisite of hepatocarcinogenesis,even in the absence of cirrhosis,is rising rapidly.The early detection of HCC has been crucial in improving the survival outcomes of those patients.However,in the mostly obese NASH population,diagnostic sensitivity of ultrasound-based HCC screening approaches is limited.On the other hand,biomarkers for HCC show promising potential to improve early detection,providing reproducible,investigator-independent results that can be used either alone or integrated with other biomarkers for scoring models.In the past,validation has been limited due to a lack of prospective longitudinal cohort studies.At present,large-scale retrospective phase-III-biomarker-development gives hope for the availability of biomarker-based screening approaches in the near future.This review focuses on the potential impact of biomarkers on surveillance strategies,potentially allowing for earlier HCC diagnosis.Jan Best Svenja Sydor Lars P.Bechmann Ali Canbay 2020Hepatoma Research2020,6,9:0
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