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| 1 | Polysaccharide-based nanomedicines for cancer immunotherapy:A review显示文摘Cancer immunotherapy is an effective antitumor approach through activating immune systems to eradicate tumors by immunotherapeutics.However,direct administration of“naked”immunotherapeutic agents(such as nucleic acids,cytokines,adjuvants or antigens without delivery vehicles)often results in:(1)an unsatisfactory efficacy due to suboptimal pharmacokinetics;(2)strong toxic and side effects due to low targeting(or off-target)efficiency.To overcome these shortcomings,a series of polysaccharide-based nanoparticles have been developed to carry immunotherapeutics to enhance antitumor immune responses with reduced toxicity and side effects.Polysaccharides are a family of natural polymers that hold unique physicochemical and biological properties,as they could interact with immune system to stimulate an enhanced immune response.Their structures offer versatility in synthesizing multifunctional nanocomposites,which could be chemically modified to achieve high stability and bioavailability for delivering therapeutics into tumor tissues.This review aims to highlight recent advances in polysaccharide-based nanomedicines for cancer immunotherapy and propose new perspectives on the use of polysaccharide-based immunotherapeutics. | Yujun Zeng Yufan Xiang Ruilong Sheng Helena Tomás João Rodrigues Zhongwei Gu Hu Zhang Qiyong Gong Kui Luo | 2021 | Bioactive Materials2021，6，10： | 3 |
| 2 | microRNA-mediated repression of rolled leafl specifies maize leaf polarity显示文摘 | Juarez M T Kui J S Thomas J | 2004 | Nature2004，428，： | 1 |
| 3 | Normal serumam in transferase levels and the metabolic syndrome: Korean National Health and Nutrition Ex- amination Survey显示文摘 | HYEON C K KUI S C | 2006 | Yonsei Med J2006，47，4： | 1 |
| 4 | MicroRNA-mediated repression of rolled leafl specifies maize leaf polarity 显示文摘 | Juarez M T Kui J S Thomas J Heller B A Timrnermans M C | 2004 | Nature2004，428，： | 1 |
| 5 | Molecular basis of classical mevalonic aciduria and the hyperimmuno- globulinaemia D and periodic fever syndrome: high fre- quency of 3 mutations in the mevalonate kinase gene 显示文摘 | Houten S M Frenkel J Kuis W | 2000 | J Inherit Metab Dis2000，23，4： | 1 |
| 6 | Reperfusion brain injury:Focus on cellular bioenergetics 显示文摘 | Pundik S Xu Kui Sundararajan S | 2012 | Neurology2012，79，13： | 1 |
| 7 | Tumor markers CEA,CA19-9 and CA125 in monitoring of response to systemicchemotherapy in patients with advanced gastric cancer显示文摘 | Yamao J Kui S Kazami A | 1999 | Jpn J Clin 0nco11999，29，11： | 1 |
| 8 | Feature selection for high-dimensional machinery fault diagnosis data using multiple models and radial basis function networks 显示文摘 | Zhang Kui Li Yu-hua Philip S | 2011 | Neurocomputing2011，74，17： | 1 |
| 9 | Systemic JIA: new developments in the understanding of the pathophysiology and therapy 显示文摘 | Vastert S J Kuis W Grom AA | 2009 | Best Pract Res Clin Rheumatol2009，23，5： | 1 |
| 10 | Platinum(Ⅱ) Complexes with π-Conjugated, Naphthyl-substituted, Cyclometalated Ligands (RC^N^N) : Structures and Photo- and Electroluminescence 显示文摘 | Kui S C F Sham I H T Cheung C C C | 2007 | Chem Eur J2007，13，： | 1 |
| 11 | Synthesis, Photophysical and Electrophosphoreseent Properties of Fluorene-based Platinum(Ⅱ) Complexes显示文摘 | Yuen M Y Kui S C F Low K H | 2010 | Chem Eur J2010，16，14： | 1 |
| 12 | Self-assembly of a cyclic metalladecapyridine from the reaction of 2,6 bis ( bis ( 2-pyridyl ) methoxymethane ) pyridine with silver(I)显示文摘 | HUANG J S XIE J KUI S C F | 2008 | Inorganic Chemistry2008，47，13： | 1 |
| 13 | The cytotoxic po- tential of interleukin-15-stimulated cytokine-induced killer cells against leukemia cells显示文摘 | Rettinger E Kui S Naumann I | 2012 | Cytotherapy2012，14，1： | 1 |
| 14 | Measurement of func- tional ability following traumatic brain injury using the clini- cal outcomes variable scale: a reliability study 显示文摘 | Choy N Kuys S Riehards M | 2002 | Austr J Physiother2002，48，： | 1 |
| 15 | Poly(divinylbenzene alt maleic anhydride)microgel:Intermediates to microspheres and macrogels in cross-linking copolymerization显示文摘 | Randy S F Jeffrey S D Kui Yu | 2002 | Macromolecules2002，35，： | 1 |
| 16 | A retrospective analysis of two independent prospective cartilage repair studies:Autogenous perichondrial grafting versus subchondral drilling 10 years post-surgery显示文摘 | Bouwmeester P S Kui j R Homminga G N | 2002 | J Orthop Res2002，20，2： | 1 |
| 17 | Neutron and X-ray diffraction and spectroscopic investigations of intramolecular (C-H center dot center dot center dot F-C) contacts in post- metallocene polyolefin catalysts: modeling weak attractive poly- mer-ligand interactions显示文摘 | Chan M C W Kui S C F Cole J M | 2006 | Chem Eur J2006，12，9： | 1 |
| 18 | Obsercation of intramolecnlar C-H center dot center dot center dot F-C contacts in non- metallocene polyolefin catalysts: model for weak attractive interactions between polymer chain and noninnocent ligand 显示文摘 | Kui S C F Zhu N Chan M C W | 2003 | Angew Chem Int Ed2003，42，14： | 1 |
| 19 | Efficient white organic light-emitting devices based on phosphorescent plati- num (Ⅱ)/fluorescent dual-emitting layers 显示文摘 | Yan B P Cheung C C C Kui S C F | 2007 | Advanced Materials2007，19，21： | 1 |
| 20 | A Data Mining Framework for Building Intrusion Detection Models显示文摘 | Wenke Lee Stolfo S J Kui Mok K | 1999 | In IEEE Symposium on Security and Privacy1999，，： | 1 |
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