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| 1 | Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies显示文摘BACKGROUND Recurrent acute pancreatitis(RAP)may be a presenting feature of and an indication for resection of pancreatic cysts,including intra-ductal papillary mucinous neoplasm(IPMN).Few data are available regarding the prevalence of malignancy and post-operative RAP in this population.AIM To study the role of resection to help prevent RAP and analyze if presentation as RAP would be a predictor for malignancy.METHODS This retrospective study assessed 172 patients who underwent surgical resection of pancreatic cystic neoplasms at a university hospital between 2002 and 2016.The prevalence of preoperative high-risk cyst features,and of neoplasia was compared between patients with and without RAP.To identify the cause of pancreatitis,all the patients had a detailed history of alcohol,smoking,medications obtained,and had cross-sectional imaging(contrast-enhanced computed tomography/magnetic resonance imaging)and endoscopic ultrasound to look for gallstone etiology and other structural causes for pancreatitis.The incidence of RAP post-resection was the primary outcome.RESULTS IPMN accounted for 101 cases(58.7%){[branch duct(BD)59(34.3%),main duct(MD)42](24.4%)}.Twenty-nine(16.9%)presented with RAP(mean 2.2 episodes):15 had BD-IPMN,8 MD-IPMN,5 mucinous cystic neoplasm and 1 serous cystic neoplasm.Malignancy was similar among those with vs without RAP for all patients[6/29(20.7%)vs 24/143(16.8%)]and IPMN patients[6/23(26.1%)vs 23/78(29.5%)],although tended to be higher with RAP in BD-IPMN,[5/15(33.3%)vs 3/44(6.8%),P=0.04].At mean follow-up of 7.2 years,1(3.4%)RAP patient had post-resection RAP.The mean episodes of acute pancreatitis before vs after surgery were 3.4 vs 0.02(P<0.0001).CONCLUSION Malignancy was not increased in patients with pancreatic cystic neoplasms who have RAP compared to those without RAP.In addition,specific cyst characteristics were not clearly associated with RAP.The incidence of RAP was markedly decreased in almost all patients following cyst resection. | Thiruvengadam Muniraj Harry R Aslanian Loren Laine Priya A Jamidar James F Farrell Kisha A Mitchell Ronald R Salem | 2021 | World Journal of Gastroenterology2021，27，15： | 3 |
| 2 | Genetic diversity among soybean plant introductions and north American germplasm显示文摘 | Kisha T Diers B W Hoyt J M | 1998 | Crop Science1998，38，： | 1 |
| 3 | Multiresolution registration of remote sensing imagery by optimization of mutual information using a stochastic gradient显示文摘 | Arlene A Cole-Rhodes Kisha L Johnson Jacqueline LeMoigne | 2003 | IEEE Transactions on Image Processing2003，12，12： | 1 |
| 4 | Muhiresolution Registration of Remote Sensing Imagery by Optimization of Mutual Information Using a Stochastic Gradient显示文摘 | Arlene A Cole-Rhodes Kisha L Johnson Jacqueline LeMoigne | 2003 | Image Processing IEEE Transactions2003，12，12： | 1 |
| 5 | The relation of genetic distance and genetic variance in populatians of soybean显示文摘 | Kisha T Sneller C H Diers B W | 1997 | Crop Science1997，37，： | 1 |
| 6 | Serous Cystadenoma in Communication With the Pancreatic Duct: An Unusual Radiologic and Pathologic Entity显示文摘 | Loren Berman Kisha A. Mitchell Gary Israel Ronald R. Salem | 2010 | Journal of Clinical Gastroenterology2010，，6： | 1 |
| 7 | RFLP and coeffieient of parentage analyses of diversity in elite and plant introduction soybean populations 显示文摘 | Sneller C Diers B Kisha T | 1994 | Agronomy Abstracts1994，213，： | 1 |
| 8 | Genetic diversity, population structure and genome-wide marker-trait association analysis emphasizing seed nutrients of the USDA pea (Pisum sativum L.) core collection显示文摘 | Soon-Jae Kwon Allan Brown Jinguo Hu Rebecca McGee Chasity Watt Ted Kisha Gail Timmerman-Vaughan Michael Grusak Kevin McPhee Clarice Coyne | 2012 | Genes & Genomics2012，，3： | 1 |
| 9 | Multiresolution Registration of Remote Sensing Imagery by Optimization of Mutual Information Using a Stochastic Gradient显示文摘 | Arlene C Kisha J Jacqueline L | 2003 | IEEE Transactions on Image Processing2003，12，12： | 1 |
| 10 | A novel one-pot conversion of a/lyl a/eohols into primary allyl ha/ides mediated by ace- tyl halide显示文摘 | Kisha/i N Polat M F | 2008 | nelv Chim Acta2008，91，1： | 1 |
| 11 | Radiology Estimates of Viable Tumor Percentage in Hepatocellular Carcinoma Ablation Cavities Correlate Poorly With Pathology Assessment显示文摘 | Hanson Joshua Anspach Ason Regina Weinreb Jeffrey Van Dyke Alison Mitchell Kisha Anne | 2013 | Archives of Pathology & Laboratory Medicine2013，，3： | 1 |
| 12 | Differences in germinal centre and non-germinal center phenotype in gastric and intestinal diffuse large B-cell lymphomas显示文摘 | Kisha A. Mitchell William G. Finn Scott R. Owens | 2008 | Leukemia & Lymphoma2008，，9： | 1 |
| 13 | Apneainclucedrapideyemovementsleepchiruptionimpairshumanspatialnangationalmemory显示文摘 | VargaAW KishA MantuaJ etal | 2014 | JNeurosci2014，34，14： | 1 |
| 14 | The relation of genetic distance and genetic variance in populations of soybean 显示文摘 | Kisha T Sneller C H Diers B W | 1997 | Crop Science1997，37，： | 1 |
| 15 | Genetic mapping of soybean cyst nematode resistance genes from PI 88788显示文摘 | Diers B W A P Rao- Arelli T Kisha | 1997 | Soybean Genet Newsl1997，24，： | 1 |
| 16 | Genetic diversity among soybean plant introductions and North American germplasm显示文摘 | Kisha T Diers B W Hoyt J M | 1998 | Crop Science1998，3，： | 1 |
| 17 | Mesenchymal stem cells for kidney transplantation显示文摘The long term consequence of immunosuppressive therapy in kidney transplantation has prompted investigation of alternative means to modify the immune response to the allograft. Cell based therapies are potentially attractive as they may provide a long lasting immunomodulatory effect, may repair tissues and reduce the necessity to take immunosuppressive drug therapy. Of the current cell therapies, mesenchymal stem cells have now been trialled in small numbers of human kidney transplantation with apparent safety and potential efficacy. Many issues however need to be resolved before these cells will become mainstays of transplant immunosuppression including ex vivo modification to enhance immunomodulatory properties, cell number, route and frequency of administration as well as cellular source of origin. | Bron Lett Kisha N Sivanathan P Toby Coates | 2014 | World Journal of Clinical Urology2014，3，2： | 0 |
| 18 | Vitreous microparticles contain apoptotic signals suggesting a diabetic vitreopathy显示文摘AIM:To evaluate differences in microparticle profiles in vitreous samples between diabetic and non-diabetic eyes undergoing vitrectomy.METHODS:Un-masked cross-sectional series of 34 eyes undergoing vitrectomy.Vitreous specimens were collected and processed to evaluate for membrane integrity(DAPI),apoptosis(Annexin-V),and endothelial-cell origin(V-Cadherin).A BD LSR II flow cytometer was used for analysis and standardized sub-micron-sized beads were used for size comparison.RESULTS:Thirty-four specimens underwent analysis.Greater levels of Annexin-V were found on microparticles from specimens in which blood had entered the vitreous(n=12)compared to those without blood(n=22;52.3%±30.7%vs 19.6%±27.2%,P=0.002).Patients with diabetes having surgery with hemorrhage(n=7)had greater expression of Annexin-V than those without hemorrhage(n=8;62.1%±31.7%vs 18.9%±20.9%,P=0.009).However,in patients with non-diabetic vitreous hemorrhage,the level of Annexin-V expression was not significantly different compared to other disease processes(38.6%±25.7%,n=5 vs 20.0%±30.9%,n=14,P=0.087).CONCLUSION:Increased expression of the apoptotic marker,Annexin-V is detected on vitreous microparticles in diabetes-related vitreous hemorrhage.When evaluating vitreous hemorrhage in patients without diabetes,the apoptotic signal is not significantly different.Vitrectomy in patients with diabetes,and improvement in visual outcomes,may be related to the removal of a serumderived,pro-apoptotic vitreous.Further investigation is warranted in order to identify the molecular characteristics of microparticles that regulate disease. | Harris Sultan Rithwick Rajagopal Prabakar Kumar Rao Kisha Deslee Piggott Michael A Paley Lynn Marisa Hassman Albert S.Li Brigid Marshall Rajendra Shridhar Apte | 2022 | International Journal of Ophthalmology(English edition)2022，15，1： | 0 |
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