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| 1 | Lipopolysaccharide Enhances the Production of Nicotine-Induced Prostaglandin E2 by an Increase in Cyclooxygenase-2 Expression in Osteoblasts显示文摘以前的研究显示了那脂肪的多糖(LPS ) 在匾的 fromGram 否定的细菌导致前列腺素 E_2 (PGE_2 ) 的版本,它在吸烟的 periodontitis,和那棵烟草支持牙槽的骨头再吞可能是为 periodontitis 的发展和严厉的一个重要风险因素。我们在碱性磷酸酶(ALPase ) 上决定了烟碱 andLPS 的效果活动, PGE_2 生产,和表示 ofcyclooxygenase (COX-1, COX-2 ) , PGE_2 受体 Ep1-4,和在人的 osteoblastic Saos-2 房间的巨噬细胞殖民地刺激因素(M-CSF ) 。房间与 10 ~ 是有教养的(-3) M 烟碱面对 0, 1,或 10 μ g /ml LPS,或与 LPS 独自一个。ALPase 活动独自在与烟碱或 LPS 有教养的房间减少了,并且在与烟碱和 LPS 有教养的那些进一步减少了,而 PGE_2 生产显著地在前者增加了并且在后者进一步增加了。由自己,烟碱没影响 COX-1, COX-2,任何 PGE_2 受体,或 M-CSF 的表示,但是烟碱和 LPS 什么时候是现在, COX-2 的表示, Ep3, Ep4,和 M-CSF,显著地增加。10 ~ 的同时的增加(-4) M 消炎痛在 ALPase 活动, PGE_2 生产,和 M-CSF 表示消除了烟碱和 LPS 的效果。proteinkinase A 的 Phosphorylation 在与烟碱和 LPS 有教养的房间高。这些结果建议 LPS 由造骨细胞的 COX-2 表示的增加提高导致烟碱的 PGE_2 的生产, thatnicotine-LPS-induced PGE_2 首先在 autocrine orparacnne 模式与造骨细胞 Ep4 受体交往,并且 nicotine-LPS-induced PGE_2 然后减少 ALPase 活动和 increasesM-CSF 表示。 | Maiko SHOJI Natsuko TANABE Narihiro MITSUI Naoto SUZUKI Osamu TAKEICHI Tomoko KATONO Akira MOROZUMI Masao MAENO | 2007 | Acta Biochimica et Biophysica Sinica2007,39,3: | 9 |
| 2 | Nicotine Treatment Induces Expression of Matrix Metalloproteinases in Human Osteoblastic Saos-2 Cells显示文摘烟草吸烟是为发展的一个重要风险因素 severeperiodontitis.Recently,我们证明那烟碱影响了使矿物化的小瘤形成,和那烟碱,脂肪的多糖由增加巨噬细胞的生产刺激了像骨破折的房间的形成刺激殖民地的因素(M-CSF )和由 humanosteoblastic Saos-2 房间的前列腺素 E_2 ( PGE_2 )。在现在的学习,我们在矩阵 metalloproteinases ( MMP )的表示上检验了烟碱的效果,矩阵 metalloproteinases ( TIMP )的织物禁止者,包括织物类型 plasminogen ( tPA )的部件的 theplasminogen 激活系统,尿激类型 PA (在 A 上面),并且 PA 禁止者类型 1 ( PAI-1 ),高山哈 7 烟碱受体,和 c-fos.Wealso 在 MMP-1.Gene 的导致烟碱的表示上检验了烟碱对手 D-tubocurarine 的效果表示用对 estimatemRNA 层次的即时聚合酶链反应( PCR )被检验。另外, MMP 的表示, TIMP 在 A 上面, tPA,和 PAI-1 蛋白质被西方的弄污决定分析。烟碱处理引起了 MMP-1,2,3 的表示,并且 13 ,然而并非 MMP-14 ,在文化的 5 或 10 d 以后显著地增加; MMP-14 表示没由烟碱处理通过 MMP-1 表示的 day14.Enhancement 变化被同时的处理与 D-tubocurarine.In 消除烟碱的存在,表示在 A 上面, PAI-1 ,或 TIMP-1,2,3 ,或 4 没改变文化的超过 14 d ,而 tPA 的表示在白天显著地增加了 7 。烟碱也增加了高山的表示哈 7 烟碱受体和 c-fos 基因。这些结果建议那烟碱由增加 tPA 和 MMP-1,2,3 的生产刺激骨头矩阵周转, and13,从而向后者过程付小费给在骨头矩阵形成和再吞之间的平衡。 | Tomoko KATONO Takayuki KAWATO Natsuko TANABE Naoto SUZUKI Kazuhiro YAMANAKA Hitoshi OKA Masafumi MOTOHASHI Masao MAENO | 2006 | Acta Biochimica et Biophysica Sinica2006,38,12: | 5 |
| 3 | Perforin and lymphohistioeytosis proliferative disorders 显示文摘 | Katono H Cohen JI | 2005 | Br J Haemetol2005,128,6: | 1 |
| 4 | Introduction of Cu(Ⅱ) complex into transparent synthetic resin and optical function of the resin as a nearinfrared ray cutoff fiher显示文摘 | Hiroki Katono Teruo Sakagami Masuhiro Shouji | 1998 | Journal of Applied Polymer Science1998,67,: | 1 |
| 5 | Thermo-responsive swelling and drug release switching of interpenetrating polymer networks composed of poly(acrylamide-co-butyl methacrylate)and poly(acrylic acid)显示文摘 | Maruyama A Sanui K | 1991 | Journal of Controlled Release1991,16,: | 1 |
| 6 | Temperature-responsive interpenetrating polymer networks constructed with poly (acrylic acid) and poly (N, N-dimethylacrylamide)显示文摘 | Aoki T Kawashima M Katono H | 1994 | Macromolecules1994,27,4: | 1 |
| 7 | Effects of Swirler Shape on Swirling Annular Flow in a Gas-Liquid Separator显示文摘 | Toshiki Matsubayashi Kenichi Katono Kosuke Hayashi | 2012 | Nuclear Engineering and Design2012,249,: | 1 |
| 8 | Circulating tumor cells as a prognostic factor in patients with smallcell lung cancer显示文摘 | Satoshi Igawa Keigo Gohda Tomoya Fukui Shinichiro Ryuge Sakiko Otani Akinori Masago Jun Sato Katsuhiro Murakami Sachiyo Maki Ken Katono Akira Takakura Jiichiro Sasaki Yukitoshi Satoh Noriyuki Masuda | 2014 | Oncology Letters2014,,5: | 1 |
| 9 | Effects of nicotine and lipopoly -saccharide on the expression of matrix metalloproteinases, plasminogen activators, and their inhibitors in human osteoblasts 显示文摘 | Katono T Kawato T Tanabe N | 2009 | Arch of Oral Biol2009,54,2: | 1 |
| 10 | Temperature-responsive interpenetrating polymer networks constructed with poly(acrylic acid) and poly( N, N-dimethylacrylamide) 显示文摘 | Aoki T Kawashima M Hiroki Katono | 1994 | Macromolecules1994,27,4: | 1 |
| 11 | Temperature-responsive Interpenetrating Polymer Networks Constructed with Poly(acrylic acid) and Poly(N,N-dimethylacrylamide)显示文摘 | Aoki T Kawashima M Katono H | 1994 | Macromolecules1994,27,4: | 1 |
| 12 | A Case of Lung Adenocarcinoma with Coexisting G719X and T790M EGFRMutations in Which Erlotinib Was Effective for the Treatment of Leptomeningeal Carcinomatosis显示文摘 | Katono K Kasajima M Ishihara M | 2013 | Gan to Kagaku Ryoho2013,40,3: | 1 |
| 13 | Effects of nicotine and lipopolysaccharide on the expression of matrix metalloproteinas- es, plasminogen activators, and their inhibitors in human osteoblasts显示文摘 | Katono T Kawato T Tanabe N | 2009 | Arch Oral Biol2009,54,2: | 1 |
| 14 | Introduction of Cu( Ⅱ) Complex into Transparent Synthetic Resin and Optical Function of the Resin as a Near-Infrared Ray Cutoff Filter显示文摘 | Hiroki Katono Teruo Sakagami Masuhiro Shouji | 1998 | Journal of Applied Polymer Science1998,,67: | 1 |
| 15 | Introduction of Cu( II )Complex into Transparent Synthetic Resin and Optical Function of the Resin as a Near-Infrared Ray Cutoff Filter 显示文摘 | Hiroki Katono Teruo Sakagami Masuhiro Shouji | 1998 | Journal of Applied Polymer Science1998,,67: | 1 |
| 16 | Optical plastic filter containing copper benzoate (Ⅱ) 显示文摘 | Katono H Ogihara T Sakagami T | 1994 | Kobunshi Ronbunshu1994,51,12: | 1 |
| 17 | Effects of nicotine and lipopolysaccharide on the expression of matrix metallo- proteinases, plasminogen activators, and their inhibitors in human osteoblasts 显示文摘 | Katono T Kawato T Tanabe N | 2009 | Arch Oral Biol2009,54,2: | 1 |
| 18 | Prognostic significance of MYH9 expression in resected non-small cell lung cancer 显示文摘 | Katono K Sato Y Jiang SX | 2015 | PLoS One2015,10,3: | 1 |
| 19 | 显示文摘 | Katono H Sanui K Ogata N | 1991 | Polym J1991,23,10: | 1 |
| 20 | Sodium butyrate stimulates mineralized nodule formation and osteoprotegerin expression by hu- man osteoblasts显示文摘 | Katono T Kawato T Tanabe N | 2008 | Arch Oral Biol2008,53,10: | 1 |