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| 1 | Adenoid cystic carcinoma of breast: Recent advances显示文摘Adenoid cystic carcinoma(ACC) of the breast is a rare special subtype of breast cancer characterized by the presence of a dual cell population of luminal and basaloid cells arranged in specific growth patterns. Most breast cancers with triple-negative, basal-like breast features(i.e., tumors that are devoid of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 expression, and express basal cell markers) are generally high-grade tumors with an aggressive clinical course. Conversely, while ACCs also display a triple-negative, basal-like phenotype, they are usually low-grade and exhibit an indolent clinical behavior. Many discoveries regarding the molecular and genetic features of the ACC, including a specific chromosomal translocation t(6;9) that results in a MYB-NFIB fusion gene, have been made in recent years. This comprehensive review provides our experience with ACC of the breast, as well as an overview of clinical, histopathological, and molecular genetic features. | Kosuke Miyai Mary R Schwartz Mukul K Divatia Rose C Anton Yong Wook Park Alberto G Ayala Jae Y Ro | 2014 | World Journal of Clinical Cases2014,2,12: | 16 |
| 2 | Synergistic and feedback signaling mechanisms in the regulation of inflammation in respiratory infections显示文摘肺病,最典型、经常的更低的呼吸的道感染(LRTI ) ,是在美国的健康问题的一个领先的原因。细菌在孩子和成年人代表肺病的大多数占优势的原因。尽管有单个细菌的感染的肺病是普通的,有肺病的病人的重要部分是 polymicrobial。这感染经常是有象 cytokines 那样的另外的生理的因素和生长因素的 complexed。Nontypeable Haemophilus influenzae (NTHi ) 是在呼吸系统的最经常恢复的克否定的细菌的病原体并且导致强壮的煽动性的回答。NTHi 另外有另外的呼吸病原体的 synergizes 例如链球菌 pneumoniae 和呼吸病毒和支持 inflammatory cytokines,例如肿瘤坏死 factor-alpha (TNF-α) 。它是引人注目的那 NTHi 不仅有象转变生长因素贝它那样的生长因素的 synergizes (TGF-β) ,而且利用象 TGF-β 那样的生长因素受体;受体和表皮的生长因素受体(EGFR ) ,提高煽动性的回答。尽管适当发炎是对入侵病原体的保护的回答,不受管束的煽动性的回答对主人经常有害。因此,发炎必须紧被调整。人的免疫系统为控制 overactive 发展了策略煽动性的反应。一如此的重要机制经由为发炎的否定反馈管理者的规定。CYLD,多功能的 deubiquitinase,是原来作为肿瘤 suppressor 报导了,但是最近为原子 factor-kappa B 作为一个否定管理者被识别(NF-κ B ) 发信号。它被 NTHi 和 TNF-α 导致;经由 NF-κ B 依赖的机制,从而为紧在 NTHi 感染控制发炎用作一个可诱导的否定反馈管理者。 | Wenzhuo Y Wang Jae Hyang Lim Jian-Dong Li | 2012 | Cellular & Molecular Immunology2012,9,2: | 10 |
| 3 | Renal cell carcinoma: Evolving and emerging subtypes显示文摘Our knowledge of renal cell carcinoma(RCC) is rapidly expanding. For those who diagnose and treat RCC, it is important to understand the new developments. In recent years, many new renal tumors have been described and defined, and our understanding of the biology and clinical correlates of these tumors is changing. Evolving concepts in Xp11 translocation carcinoma, mucinous tubular and spindle cell carcinoma, multilocular cystic clear cell RCC, and carcinoma associated with neuroblastoma are addressed within this review. Tubulocystic carcinoma, thyroid-like follicular carcinoma of kidney, acquired cystic disease-associated RCC, and clear cell papillary RCC are also described. Finally, candidate entities, including RCC with t(6;11) translocation, hybrid oncocytoma/chromophobe RCC, hereditary leiomyomatosis and RCC syndrome, and renal angiomyoadenomatous tumor are reviewed. Knowledge of these new entities is important for diagnosis, treatment and subsequent prognosis. This review provides a targeted summary of new developments in RCC. | Suzanne M Crumley Mukul Divatia Luan Truong Steven Shen Alberto G Ayala Jae Y Ro | 2013 | World Journal of Clinical Cases2013,1,9: | 7 |
| 4 | Addition of docetaxel to S-1 without platinum prolongs survival of patients with advanced gastric cancer: a randomized study (START)显示文摘 | Wasaburo Koizumi Yeul Hong Kim Masashi Fujii Hoon Kyo Kim Hiroshi Imamura Kyung Hee Lee Takuo Hara Hyun Cheol Chung Taroh Satoh Jae Yong Cho Hisashi Hosaka Akihito Tsuji Akinori Takagane Mikito Inokuchi Kazuaki Tanabe Tatsuya Okuno Mariko Ogura Kazuhiro Y | 2014 | Journal of Cancer Research and Clinical Oncology2014,,2: | 2 |
| 5 | Fine Root Biomass, Production and Turnover in a Fertilized Larixin leptolepis Plantation in Central Korea显示文摘 | Son Y Jae H H | 2003 | Ecological Research2003,18,: | 1 |
| 6 | Understanding Information Technology Acceptance by Individual Professionals: Toward an Integrative View显示文摘 | Mun Y Yi Joyce D Jackson Jae S Park | 2006 | Information and Management2006,43,3: | 1 |
| 7 | New hybrid method for simultaneousimprovement of tensile and impact properties of carbon fiber reinforcedcomposites显示文摘 | Seong Y K Soo J B Jae R Y | 2011 | Carbon2011,49,15: | 1 |
| 8 | Angiotensin I Converting Enzyme (ACE) Inhibitory Peptide Derived from the Sauce of Fermented Blue Mussel,Mytilus Edulis显示文摘 | JAE Y J PYO J P HEE G B | | 0,,: | 1 |
| 9 | Selective adsorption of flavoniod compounds from the leaf extract of Ginkgo biloba L显示文摘 | Yoon Sung Y Choi Won Jae Park Jong Moon | 1997 | Biotechnol Tech1997,11,8: | 1 |
| 10 | Evidence that pro- tease-activated receptor-2 mediate trypsin-induced reversal of stellation in cultured rat astrocytes 显示文摘 | Gyu H P Jae R R Shin Ch Y | 2006 | Neuroscience Research2006,,54: | 1 |
| 11 | Laser clad Ni-base alloy added nano- and micron-size CeO2 composites显示文摘 | Zhang S H Li M X Tong Yul Cho Jae Hong Yoon Chan Gyu Lee and He Y Z | 2008 | Optics & Laser Technology2008,40,5: | 1 |
| 12 | Improved method for efficient production of biodiesel from palm oil显示文摘 | RAHMAN TALUKDER M M MIN BEATRICE K L PUAY SONG O PUAH S CHUAN WU J JAE WON C CHOW Y | 2008 | Energy Fuels2008,22,1: | 1 |
| 13 | REGARD:A phase III,randomized,double-blinded trial of ramucirumab and best supportive care(BSC)versus placebo and BSC in the treatment of metastatic gastric or gastroesophageal junction(GEJ)adenocarcinoma following disease progression on first-line platinum-and/or fluoropyrimidine-containing combination therapy显示文摘 | Charles S Fuchs Jiri T Jae Y | 2012 | J Clin Oncol2012,,: | 1 |
| 14 | A Review of Ecological Impacts of Oil and Gas Development on Coastal Ecosystems in the Mississippi Delta显示文摘 | JAE Y K JOHN W D | 2004 | Ocean & Coastal Management2004,47,1112: | 1 |
| 15 | Differential expression of nuclear retinoid receptors in normal, premalignant, and malignant head and neck tissues显示文摘 | Xiao-chun XU Jae Y Ro Jin S Lee | 1994 | Cancer Research1994,54,: | 1 |
| 16 | The clinical features of drug-induced Liver injury observed through liver biopsy: fo- cus on relevancy to autoimmune hepatitis显示文摘 | HYE Y J JAE Y J SOUNG W J | 2012 | Cfin Mol Hep- atology2012,18,2: | 1 |
| 17 | Wavelength switching in an actively mode-locked Fabry-Perot laser diode with a highly disper-sive external cavity显示文摘 | Young K D | 2006 | Applied Optics2006,45,14: | 1 |
| 18 | The inverse associationbetween cardiorespiratory fitness and C-reactive protein is mediatedby autonomic function:a possible role of the cholinergic antiin-flammatory pathway显示文摘 | Jae S Y Heffernan K S Yoon E S | 2009 | Mol Med2009,15,910: | 1 |
| 19 | Effects of a cationic diblock copolymer derived fromtrimethylammonium chloride in the dyeing of cotton with reactive dye显示文摘 | HANS Y CHUN K J JAE Y J | 2008 | Coloration Technology2008,124,4: | 1 |
| 20 | Cellular change and calloseaccumulation in zygotic embryos of Eleutherococcus senticosuscaused by plasmolyzing pretreatment result in high frequency ofsingle- cell- derived somatic embryogenesis显示文摘 | You X L Jae Seon Y Choi Y E | 2006 | Protoplasma2006,227,: | 1 |