|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | To Bloom or Not to Bloom: Role of MicroRNAs in Plant Flowering显示文摘在他们的生命周期的功课期间,植物经历位于 juvenile-to-adult 和 adult-to-flowering 阶段转变下面的各种各样的词法、生理的变化。是向它的新生命周期的开始的植物的粘性的关键步到花到花。除了以前揭示的内在的基因节目,外长的暗示,和内长的暗示,小非编码的 RNA 的一个班, microRNAs (miRNAs ) ,在由集成到已知的 flowering 小径作决定到花的植物起一个关键作用。这评论在决定如此的一个关键过程与很多预定 miRNAs 的一个焦点加亮年龄依赖者 flowering 小径。主要在年龄小径外面存在的另外的 miRNAs 的贡献也被讨论。学习决定花的 miRNAs,他们的相互作用,和应用程序的途径被介绍。 | Sachin Teotia | 2015 | Molecular Plant2015，8，3： | 30 |
| 2 | A Resource for Inactivation of MicroRNAs Using Short Tandem Target Mimic Technology in Model and Crop Plants显示文摘microRNAs (miRNAs)are endogenous small non-coding RNAs that bind to mRNAs and target them for cleavage and/or translational repression,leading to gene silencing.We previously developed short tandem target mimic (STTM)technology to deactivate endogenous miRNAs in Arabidopsis.Here,we created hundreds of STTMs that target both conserved and species-specific miRNAs in Arabidopsis,tomato,rice,and maize,providing a resource for the functional interrogation of miRNAs.We not only revealed the functions of several miRNAs in plant development,but also demonstrated that tissue-specific inactivation of a few miRNAs in rice leads to an increase in grain size without adversely affecting overall plant growth and development.RNA-seq and small RNAseq analyses of STTM156/157 and STTM165/166 transgenic plants revealed the roles of these miRNAs in plant hormone biosynthesis and activation,secondary metabolism,and ion-channel activity-associated electrophysiology,demonstrating that STTM technology is an effective approach for studying miRNA functions.To facilitate the study and application of STTM transgenic plants and to provide a useful platform for storing and sharing of information about miRNA-regulated gene networks,we have established an online Genome Browser (http://gffzzc750bc0108fa4044skf55vcfwfbok6cpp.ffgz.tsg.suse.edu.cn/designindex2.php) to display the transcriptomic and miRNAomic changes in STTMinduced miRNA knockdown plants. | Ting Peng Mengmeng Qiao Haiping Liu Sachin Teotia Zhanhui Zhang Yafan Zhao Bobo Wang Dongjie Zhao Lina Shi Cui Zhang Brandon Le Kestrel Rogers Chathura Gunasekara Haitang Duan Yiyou Gu Lei Tian Jinfu Nie Jian Qi Fanrong Meng Lan Huang Qinghui Chen Zhenlin Wang Jinshan Tang Xiaoqing Tang Ting Lan Xuemei Chen Hairong Wei Quanzhi Zhao Guiliang Tang | 2018 | Molecular Plant2018，11，11： | 7 |
| 3 | Short Tandem Target Mimic:A Long Journey to the Engineered Molecular Landmine for Selective Destruction/Blockage of MicroRNAs in Plants and Animals显示文摘MicroRNAs(miRNAs) are a population of highly conserved specific small ribo-regulators that negatively regulate gene expressions in both plants and animals.They play a key role in post-transcriptional gene regulation by destabilizing the target gene transcripts or blocking protein translation from them.Interestingly,these negative regulators are largely compromised by an upstream layer of negative regulators 'target mimics' found in plants or 'endogenous competing RNAs' revealed recently in animals.These endogenous regulatory mechanisms of 'double negatives making a positive' have now been developed into a key strategy in the study of small RNA functions. This review presents some reflections on the long journey to the short tandem target mimic(STTM) for selective destruction/blockage of specific miRNAs in plants and animals,and the potential applications of STTM are discussed. | Guiliang Tang Xiaoqing Tang | 2013 | Journal of Genetics and Genomics2013，40，6： | 7 |
| 4 | siRNA and miRNA: An insight into RISCs 显示文摘 | Tang Guiliang | 2005 | Trends Biochem''Sci2005，30，2： | 1 |
| 5 | siRNA and miRNA:An insight into RISCs显示文摘 | Tang Guiliang | 2005 | Trends Biochem Sci2005，30，： | 1 |
| 6 | Using RNAi to improve plant nutritional value: from mechanism to application 显示文摘 | Guiliang Tang Gad Galili | 2004 | Trends in Biotechnology2004，22，9： | 1 |
| 7 | An in vivo Transient Expression System Can Be Applied for Rapid and Effective Selection of Artificial MicroRNA Constructs for Plant Stable Genetic Transformation显示文摘The utility of artificial microRNAs(amiRNAs) to induce loss of gene function has been reported for many plant species,but expression efficiency of the different amiRNA constructs in different transgenic plants was less predictable,In this study,expressions of amiRNAs through the gene backbone of Arabidopsis miR168a were examined by both Agrobacterium-mediated transient expression and stable plant genetic transformation.A corresponding trend in expression of amiRNAs by the same amiRNA constructs between the transient and the stable expression systems was observed in the experiments.Plant genetic transformation of the constructs that were highly expressible in amiRNAs in the transient agro-infiltration assays resulted in generation of transgenic lines with high level of amiRNAs.This provides a simple method for rapid and effective selection of amiRNA constructs used for a time-consuming genetic transformation in plants. | Basdeo Bhagwat Ming Chi Li Su Haifeng Tang Guiliang Tang Yu Xiang | 2013 | Journal of Genetics and Genomics2013，40，5： | 1 |
| 8 | Using RNAi to improve plant nutritional value : from mechanism to application 显示文摘 | Guiliang Tang Gad Galili | 2004 | Trends in Biotechnology2004，22，9： | 1 |
| 9 | Differential and dynamic regulation of miR398 in response to ABA and salt stress in Populus tremula and Arabidopsis thaliana显示文摘 | Xiaoyun Jia Wang-Xia Wang Ligang Ren Qi-Jun Chen Venugopal Mendu Benjamin Willcut Randy Dinkins Xiaoqing Tang Guiliang Tang | 2009 | Plant Molecular Biology (-)2009，，1： | 1 |
| 10 | The miR167-OsARF12 module regulates rice grain filling and grain size downstream of miR159显示文摘Grain weight and quality are always determined by grain filling.Plant microRNAs have drawn attention as key targets for regulation of grain size and yield.However,the mechanisms that underlie grain size regulation remain largely unclear because of the complex networks that control this trait.Our earlier studies demonstrated that suppressed expression of miR167(STTM/MIM167)substantially increased grain weight.In a field test,the yield increased up to 12.90%-21.94% because of a significantly enhanced grain filling rate.Here,biochemical and genetic analyses revealed the regulatory effects of miR159 on miR167 expression.Further analysis indicated that OsARF12 is the major mediator by which miR167 regulates rice grain filling.Overexpression of OsARF12 produced grain weight and grain filling phenotypes resembling those of STTM/MIM167 plants.Upon in-depth analysis,we found that OsARF12 activates OsCDKF;2 expression by directly binding to the TGTCGG motif in its promoter region.Flow cytometry analysis of young panicles from OsARF12-overexpressing plants and examination of cell number in cdkf;2 mutants verified that OsARF12 positively regulates grain filling and grain size by targeting OsCDKF;2.Moreover,RNA sequencing results suggested that the miR167-OsARF12 module is involved in the cell development process and hormone pathways.OsARF12-overexpressing plants and cdkf;2 mutants exhibited enhanced and reduced sensitivity to exogenous auxin and brassinosteroid(BR)treatment,confirming that targeting of OsCDKF;2 by OsARF12 mediates auxin and BR signaling.Our results reveal that the miR167-OsARF12 module works downstream of miR159 to regulate rice grain filling and grain size via OsCDKF;2 by controlling cell division and mediating auxin and BR signals. | Yafan Zhao Xiaofan Zhang Yuan Cheng Xiangxiang Du Sachin Teotia Chunbo Miao Huwei Sun Guoqiang Fan Guiliang Tang Hongwei Xue Quanzhi Zhao Ting Peng | 2023 | Plant Communications2023，4，5： | 1 |
| 11 | Cloning and expression of an Arabidopsis thaliana cDNA encoding a monofunctional aspartate kinase homologous to the lysine-sensitive enzyme of Escherichia coli显示文摘 | Guiliang Tang Judith X. Zhu-Shimoni Rachel Amir Inbal Ben-Tzvi Zchori Gad Galili | 1997 | Plant Molecular Biology1997，，2： | 1 |
| 12 | miR-107 Regulates Granulin/Progranulin with Implications for Traumatic Brain Injury and Neurodegenerative Disease显示文摘 | Wang-Xia Wang Bernard R. Wilfred Sindhu K. Madathil Guiliang Tang Yanling Hu James Dimayuga Arnold J. Stromberg Qingwei Huang Kathryn E. Saatman Peter T. Nelson | 2010 | The American Journal of Pathology2010，，： | 1 |
| 13 | Identification and characterization of the minimal promoter of Mipul: the role of GC boxes in the regulation of basal transcription显示文摘Mipu1,编码 KRAB/C2H2 锌手指蛋白质的新奇基因,首先被报导在心肌的 ischemiareperfusion 损害起来调整,工作保护房间免于氧化应力。印射基因的倡导者区域并且理解它的规定,我们识别了抄写开始地点并且表明抄写开始地点在上游的 1366-bp 碎片拥有倡导者活动。Mipu1 的 5 胁腹区域的删除构造导致一个最小的倡导者,既不一个 TATA 盒子也不一个 CAAT 盒子在被检测的鉴定。二个 GC 盒子被发现;然而,他们是为 Sp1 家庭抄写因素的特定的有约束力的地点。在这些 GC 盒子中的变化导致了 Mipu1 最小的倡导者活动的全部的损失。最后, WP631,一个 Sp1-family-specific 禁止者,以一种剂量依赖者方式被发现倡导者活动到减少,显示 GC 盒子为 Mipu1 最小的倡导者活动的活动是必要的。 | Ben Lv Yiting Tang Xiayu Li Guiliang Wang Can Yuan Ying Liu Lei Jiang Xianzhong Xiao | 2009 | Acta Biochimica et Biophysica Sinica2009，41，4： | 0 |
| 14 | MicroRNA-mediated DNA methylation in plants显示文摘DNA methylation,a major event in epigenetics,plays an essential role in the control of gene expression.Increasing evidence suggests that long and short non-coding RNAs are involved extensively in plants to direct the establishment,spread,and removal of DNA cytosine methylation throughout their genomes.Yet,little has been known about the role of microRNAs(miRNAs)in DNA methylation although the role of small interfering RNAs(siRNAs)in DNA methylation has been well established.Several recent studies,however,provided the evidence for miRNA-directed DNA methylation in plants,and the working mechanisms still need to be fully explored.In this review,we highlight the key features of miRNA-directed DNA methylation in plants and provide insight into the complexities of such an event in plants.The interaction between miRNAs and the epigenetic machinery and the future potential research questions are briefly discussed. | Xiaoyun JIA Jun YAN Guiliang TANG | 2011 | Frontiers in Biology2011，6，2： | 0 |
| 15 | E3泛素连接酶SINAT通过光信号调控BR转录因子BES1的蛋白稳定性显示文摘文章简介油菜素甾醇(BRs)是一类促进植物生长的类固醇激素,可以调控植物多方面的生长发育过程。已有的研究表明,BES1/BZR1的活性和功能主要取决于对其磷酸化状态和蛋白稳定性的调控,但对于BES1/BZR1的调控机制尤其是降解机制,仍需进一步探究。 | Mengran Yang Chengxiang Li Zhenying Cai Yinmeng Hu Trevor Nolan Feifei Yu Yanhai Yin Qi Xie Guiliang Tang 王学路 | 2018 | 科学新闻2018，0，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员