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| 1 | Liver histology according to the presence of metabolic syndrome in nonalcoholic fatty liver disease cases显示文摘AIM:To investigate the histologic features of the liver in nonalcoholic fatty liver disease (NAFLD) cases according to the presence of metabolic syndrome or its individual components. METHODS:We enrolled 81 patients (40 male,41 fe-male) who were diagnosed with fatty liver by ultraso-nographic scan and fulfi lled the inclusion criteria. First anamnesis,anthropometric,clinical,laboratory and imaging features of all participants were recorded and then liver biopsy was performed after gaining consent from patients. Diagnosis of metabolic syndrome was dependent on patients having 3 or more out of 5 risk criteria defined by the WHO. Biopsy specimens were assessed according to Brunt et al's classification. RESULTS:Sixty-nine of the 81 patients had nonalco-holic steatohepatitis (NASH),11 had simple fatty liver and 1 had cirrhosis according to histologic evaluation. Comparisons were made between two groups of NASH patients,those with and without metabolic syndrome. We did not detect statistically significant differences in liver histology between NASH patients with and wit-hout metabolic syndrome. CONCLUSION:NASH can progress without metabolic risk factors or the presence of metabolic syndrome. | Hüseyin Saadettin Uslusoy Selim Giray Nak Macit Gülten Zeynep Blylkll | 2009 | World Journal of Gastroenterology2009，15，9： | 12 |
| 2 | Non-alcoholic steatohepatitis with normal aminotransferase values显示文摘AIM:To investigate the aspects of liver histology in patients with non-alcoholic steatohepatitis(NASH)who had normal aminotransferase levels. METHODS:Thirty-four patients diagnosed with liver steatosis by ultrasonographic examination participated in the study.We compared all nonalcoholic fatty liver disease and NASH cases,according to aminotransferase level,aspartate aminotransferase (AST)/alanine aminotransferase(ALT)ratio and presence of metabolic syndrome. RESULTS:Sixteen of 25 patients with high aminotransferase levels were diagnosed with NASH and nine with simple fatty liver according to liver histology. Among the nine patients with normal aminotransferase levels,seven had NASH and two had simple fatty liver. The patients with normal and high liver enzyme levels had almost the same prevalence of NASH and metabolic syndrome.Liver histology did not reveal any difference according to aminotransferase levels and AST/ALT ratio. CONCLUSION:Aminotransferase levels and AST/ALT ratio do not seem to be reliable predictors for NASH. Despite numerous non-invasive biomarkers,all patients with fatty liver should undergo liver biopsy. | Hüseyin Saadettin Uslusoy Selim Giray Nak Macit Gülten Zeynep B|y|kl| | 2009 | World Journal of Gastroenterology2009，15，15： | 7 |
| 3 | Profiles of serum microRNAslmiR-125b-Sp and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma 显示文摘 | Giray BG Emekdas G Tezcan S | 2014 | Mol Biol Rep2014，41，7： | 1 |
| 4 | On pricing discrete barrier options using conditional expectation and importance sampling Monte Carlo显示文摘 | Giray Emmanuel S Ahmet G | 2008 | Mathematical and Computer Modelling2008，，47： | 1 |
| 5 | Immunolocal ization of integrins and fibronectin in tubal p regnancy显示文摘 | Inan S Giray G Vatansever HS | 2004 | Acta Histochem2004，106，5： | 1 |
| 6 | Immunolocalization of integrins and fibronectin in tubal pregnancy 显示文摘 | Inan S Giray G Seda V H | 2004 | Acta Histochem2004，106，3： | 1 |
| 7 | Profiles of serum microRNAs;miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma显示文摘 | GIRAY B G EMEKDAS G TEZCAN S | 2014 | Mol Biol Rep2014，5，： | 1 |
| 8 | Cypermethrin-induced oxidative stress in rat brain and liver is prevented by Vitamin E or allopurinol显示文摘 | Giray B Gürbay A Hincal F | 2001 | Toxicology Letters2001，118，： | 1 |
| 9 | Frequency of eidetic imagery among hydrocephalic children 显示文摘 | Giray E F Altkin W M Barclay A G | 1976 | Perceptual And Motor Skills1976，43，1： | 1 |
| 10 | Incidence of eidetic imagery as a function of age 显示文摘 | Giray E F Altkin W M Vaught G M etc | 1976 | Child Development1976，47，4： | 1 |
| 11 | Profiles of serum mi- croRNAs: miR-125b-5p and miR223-3p serve as novel hi- omarkers for HBV-positive hepatocellular carcinoma显示文摘 | Giray BG Emekdas G Tezcan S | 2014 | Mol Biol Rep2014，，： | 1 |
| 12 | Immunolocalization of integrins and fibronectin in tubal pregnancy 显示文摘 | Inan S Giray G Vatansever HS | 2004 | Acta Histochem2004，106，3： | 1 |
| 13 | Effects of metformin on mammalian target of rapamycin in a mouse model of endometrial hyperplasia 显示文摘 | ERDEMOGLU E GUNEY M GIRAY S G | 2009 | Eur J Obstet Gynecol Reprod Bio12009，145，2： | 1 |
| 14 | Immunolocalization of integrins and fibronectin in tubal pregnancy 显示文摘 | Inan S Giray G Vatansever HS | 2004 | Acta Histochemica2004，106，： | 1 |
| 15 | Immunolocalization of integrins and fibronectin in tubal pregnancy显示文摘 | INAN S GIRAY G VATANSEVER HS | 2004 | Acta Histochem2004，104，37： | 1 |
| 16 | A new corrosion inhibitor for copper protection 显示文摘 | Tansug G Tüken T Giray E S F?nd?kk?ran G Sigrick G Demirkol O Erbil M | 2014 | Corrosion Science2014，84，7： | 1 |
| 17 | Noninvasive predictors for liver fibrosis in patients with nonalcoholic steatohepatitis显示文摘AIM:To evaluate certain anthropometric,clinical and laboratory features indicating liver fibrosis in nonalcoholic steatohepatitis and to establish the noninvasive markers for liver fibrosis.METHODS:Eighty-one patients (40 male,41 female) who were diagnosed with fatty liver by ultrasonographic examination and fulfilled the inclusion criteria participated in the study.Anamnesis,anthropometric,clinical and laboratory features of all cases were recorded and then liver biopsy was performed after obtaining patient consent.Steatosis,necroinflammation and liver fibrosis were examined according to age ≥ 45,gender,body mass index,central obesity,aspartate amino-transferase (AST)/alanine aminotransferase (ALT)>1,γ-glutamyltransferase (GGT)/ALT>1,platelet count,insulin,c-peptide levels and the presence of hypertension,diabetes,hypertriglyceridemia and insulin resis-tance.RESULTS:Eighty-one patients with non-alcoholic steatohepatitis (NASH) enrolled in the study.69 of 81 patients were diagnosed with NASH,11 were diagnosed with simple fatty liver and 1 was diagnosed with cirrhosis.AST/ALT>1,GGT/ALT>11,high serum ferritin and fasting insulin levels,the presence of diabetes,hypertension,hypertriglyceridemia and insulin resistance seemed to enhance the severity of steatosis,necroinflammation and fibrosis but these results were not statistically significant.CONCLUSION:Liver steatosis and fibrosis can occur in individuals with normal weight.There was no significant concordance between severity of liver histology and the presence of predictors for liver fibrosis including metabolic risk factors. | Hüseyin Saadettin Uslusoy Selim Giray Nak Macit Gülten | 2011 | World Journal of Hepatology2011，3，8： | 0 |
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