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您的检索式：作者名="Francesco Cardi"
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| 1 | Efficacy and safety of low-intensity shockwave therapy plus tadalafil 5 mg once daily in men with type 2 diabetes mellitus and erectile dysfunction:a matched-pair comparison study显示文摘Low-intensity extracorporeal shockwave therapy(LiESWT)represents a promising treatment for patients with erectile dysfunction(ED).We investigated the efficacy of LiESWT combined with tadalafil 5 mg once daily in men with type 2 diabetes mellitus(T2DM)and ED and compared LiESWT protocols administering different number of shockwaves.We performed a retrospective matched-pair comparison using data from a prospectively maintained database.Seventy-eight patients who received tadalafil 5 mg once dai7ly for 12 weeks+LiESWT performed with an electrohydraulic source for 3 weeks(Group A)were matched 1:1 to patients who received tadalafil 5 mg once daily alone for 12 weeks(Group B).A subgroup analysis was performed according to the number of shockwaves delivered during each session(1500,1800,and 2400 in subgroup A1,A2,and A3,respectively).The mean International Index of Erectile Function-5(IIEF-5)score variations with respect to baseline recorded at 4,12,and 24 weeks after the end of the treatment were investigated as treatment outcomes.The mean IIEF-5 scores significantly improved in all groups and subgroups at 4-week follow-up without intergroup differences.At 12-and 24-week follow-up,the mean IIEF-5 improvement was significantly higher among patients in the A3 subgroup(+5.0±2.1[P<0.001]and+4.7±2.3[P<0.001],respectively).The combined approach with tadalafil 5 mg once daily and LiESWT with a protocol involving 2400 shockwaves provides significant advantages in terms of IIEF-5 improvement and durability compared to tadalafil 5 mg once daily alone in patients with T2DM and ED. | Paolo Verze Marco Capece Massimiliano Creta Roberto La Rocca Francesco Persico Lorenzo Spirito Antonio Cardi Vincenzo Mirone | 2020 | Asian Journal of Andrology2020，22，4： | 8 |
| 2 | 结直肠癌标本切除长度与淋巴结转移度有关系吗?显示文摘背景:阳性淋巴结数量(LN+)和淋巴结切除总数(rLN)都会影响结直肠癌的预后,这两者的比值即淋巴结转移度(LNR)。本研究旨在评估标本切除长度(LR)对LNR预后价值的影响。方法:回顾性纳入本中心2000-2015年间的所有结直肠癌手术病例,对其病理结果进行全面分析,计算经RL调整的rLN、LN+及LNR。采用受试者操作特征(ROC)分析,评估上述指标对淋巴结转移患者的预后价值。结果:670例患者纳入研究,男性337例(50.3%),平均年龄69.2岁。无论是阳性淋巴结患者(n=312)还是所有患者(n=670),LNR与预后的相关性均强于经RL调整的LNR(LNR/RL)。ROC分析显示,除了肿瘤转移外,LNR对各个预后指标的预测价值均高于LNR/RL和RL,而LNR/RL对肿瘤转移的预测价值似乎更高一些。Kaplan-Meier生存曲线显示,LNR可有效区分不同生存时间的患者(P=0.043),而LNR/RL(P=0.373)和RL(P=0.314)都未能显示出统计学意义。结论:RL的增加在导致淋巴结获取数量的增多的同时并不会影响LN+数量,从而成为了可能改变LNR预后价值的干扰因素。但本研究结果并未发现将RL纳入考虑的LNR具有更优的预后价值,这一结果需要前瞻性大样本研究的进一步证实。 | Antonio Zanghi Andrea Cavallaro Emanuele Lo Menzo Serena Curella Botta Salvatore Lo Bianco Maria Di Vita Francesco Cardi Alessandro Cappellani | 2021 | Gastroenterology Report2021，9，3： | 0 |
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