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| 1 | Transarterial chemoembolization and bland embolization for hepatocellular carcinoma显示文摘Transarterial chemoembolization(TACE)is the first line treatment for patients with intermediate stage hepatocellular carcinoma but is also increasingly being used for patients on the transplant waiting list to prevent further tumor growth.Despite its widespread use,TACE remains an unstandardized procedure,with variation in type and size of embolizing particles,type and dose of chemotherapy and interval between therapies.Existing evidence from randomized controlled trials suggest that bland transarterial embolization(TAE)has the same efficacy with TACE.In the current article,we review the use of TACE and TAE for hepatocellular carcinoma and we focus on the evidence for their use. | Emmanuel A Tsochatzis Evangelia Fatourou James O'Beirne Tim Meyer Andrew K Burroughs | 2014 | World Journal of Gastroenterology2014，20，12： | 18 |
| 2 | Macrophage inhibitory cytokine-1/growth differentiation factor-15 in premalignant and neoplastic tumours in a high-risk pancreatic cancer cohort显示文摘BACKGROUND Pancreatic cancer(PC)is a leading cause of cancer related mortality worldwide,with poor survival due to late diagnosis.Currently,biomarkers have limited use in early diagnosis of PC.Macrophage inhibitory cytokine-1 or growth differentiation factor-15(MIC-1/GDF15)has been implicated as a potential serum biomarker in PC and other malignancies.AIM To determine the role of MIC-1/GDF15 in detecting pre-malignant pancreatic lesions and neoplastic tumours in an asymptomatic high-risk cohort part of Australian Pancreatic Cancer Screening Program.METHODS A feasibility prospective single centre cohort study was performed.Participants recruited for yearly surveillance with endoscopic ultrasound(EUS)had serial fasting blood samples collected before EUS for MIC-1/GDF15,C-reactive protein and carbohydrate antigen 19-9.Patients were stratified into five groups based on EUS findings:Normal;pancreatic cysts,branch-duct intraductal papillary mucinous neoplasm;diffuse non-specific abnormalities;and neoplastic tumours.MIC-1/GDF15 serum levels were quantified using ELISA.Participants in whom EUS demonstrated abnormalities but not malignancy were closely followed up with magnetic resonance imaging(MRI)or computed tomography.RESULTS One hundred twenty participants were prospectively recruited from 2011-2018.Forty-seven participants(39.2%)had an abnormal EUS and five participants(4.2%)were diagnosed with neoplastic tumours,three by EUS(two pancreatic and one liver)and two by MRI/computed tomography(breast cancer,bladder cancer),which were performed for follow up of abnormal EUS.Baseline serum MIC-1/GDF15 was a significant predictor of neoplastic tumours on receiver operator characteristic curve analysis[area under curve(AUC)=0.814,P=0.023].Baseline serum MIC-1/GDF15 had moderate predictive capacity for branch-duct intraductal papillary mucinous neoplasm(AUC=0.644)and neoplastic tumours noted on EUS(AUC=0.793),however this was not significant(P=0.188 and 0.081 respectively).Serial serum MIC-1/GDF15 did not demonstrate a significant percentage change between a normal and abnormal EUS(P=0.213).Median baseline MIC-1/GDF15 was greater in those with neoplastic tumours(Median=1039.6,interquartile range=727.0-1977.7)compared to those diagnosed with a benign lesion(Median=570.1,interquartile range=460.7-865.2)on EUS and MRI(P=0.012).CONCLUSION In this pilot study MIC-1/GDF15 has predictive capacity for neoplastic tumours in asymptomatic individuals with a genetic predisposition for PC.Further imagining may be warranted in patients with abnormal EUS and raised serum MIC-1/GDF15.Larger multicentric prospective studies are required to further define the role of MIC-1/GDF15 as a serological biomarker in pre-malignant pancreatic lesions and neoplastic tumours. | Robert Sean O’Neill Sam Emmanuel David Williams Alina Stoita | 2020 | World Journal of Gastroenterology2020，26，14： | 8 |
| 3 | Reduced Exposure to Calcineurin Inhibitors Early After Liver Transplantation Prevents Recurrence of Hepatocellular Carcinoma显示文摘 | Manuel Rodríguez-Perálvarez Emmanuel Tsochatzis María Carmen Naveas Giulia Pieri Carmen García-Caparrós James O’Beirne Antonio Poyato-González Gustavo Ferrín-Sánchez Jose Luis Montero-álvarez David Patch Douglas Thorburn Javier Brice?o Manuel De la Mata A | 2013 | Journal of Hepatology2013，，： | 5 |
| 4 | Association of cardiovascular system medications with cognitive function and dementia in older adults living in nursing homes in Australia显示文摘ObjectiveTo 在在检验生活和资源使用的质量的 17 所澳大利亚的疗养院的代表性的研究的 Australia.MethodsAs 部分住在疗养院的更老的成年人与认知功能和痴呆的诊断检验在心血管的系统药使用之间的协会,我们检验了在认知缺陷和心血管的药使用之间的协会(使用解剖治疗学的分类系统识别)用一般线性回归和逻辑 regressio 正在收到生活照顾的结束的人是包括的 excluded.ResultsParticipants 有一个平均数的 541 个居民 85.5 | Enwu Liu Suzanne M Dyer Lisa Kouladjian O'Donnell Rachel Milte Clare Bradley Stephanie L Harrison Emmanuel Gnanamanickam Craig Whitehead Maria Crotty | 2017 | Journal of Geriatric Cardiology2017，14，6： | 2 |
| 5 | Evaluation of a new, rapid,and quantitative D-Dimer test in patients with suspected pulmonary embolism显示文摘 | Emmanuel O Christophe L Luc B | 1998 | Am J Pespir Crit Care Med1998，158，1： | 1 |
| 6 | Vibrations of carbon nanotubes and their com- posites: A review 显示文摘 | Ronald F Gibson Emmanuel O Ayorinde Yuan-Feng Wen | 2007 | Composites Science and Technology2007，67，： | 1 |
| 7 | Mapping wound-response genes involved in post-harvest physiological deterio-ration(PPD)of cassava(Manihot esculenta Crantz)显示文摘 | DIEGO F C KIM R EMMANUEL O | 2002 | Euphytica2002，128，： | 1 |
| 8 | The role of sonographic endometrial patterns and endometrial thickness in the differential diagonosis of ectopic pregnancy 显示文摘 | Ahmad O Hammoud Ihab Hammoud Emmanuel Bujold | 2005 | Am J Obstet Gynecol2005，192，： | 1 |
| 9 | Olfactory cues of mahogany trees to female Hypsipyla robusta显示文摘 | JOHN A EMMANUEL O BERNHARD W | 2014 | B Insectol2014，67，1： | 1 |
| 10 | Effect of Moringa oleifera lectins on survival and enzyme activities of Aedes aegypti larvae susceptible and resistant to organophosphate显示文摘 | Afonso Cordeiro Agra-Neto Thiago Henrique Napole?o Emmanuel Viana Pontual Nataly Diniz Lima Santos Luciana Andrade Luz Cláudia Maria Fontes Oliveira Maria Alice Varjal Melo-Santos Luana Cassandra Breitenbach Barroso Coelho Daniela Maria Amaral Ferraz Nava | 2014 | Parasitology Research2014，，1： | 1 |
| 11 | A comparative study of the removal of heavy metal ions from synthetic wastewaters using different adsorbents显示文摘 | Oluyemi Emmanuel A Oyekunle John A O Olasoji Samuel O | 2009 | Adsorption Science & Technology2009，27，5： | 1 |
| 12 | Immobilisafion and bioelectrochemistry of proteins on nanoporous TiO2 and ZnO films 显示文摘 | Emmanuel T Anthony E G C Brian O' Regan | 2001 | J Electroanal Chem2001，517，： | 1 |
| 13 | Knowledge, Attitudes,and Practices about Malaria and Its Control in Rural Northwest Tanzania显示文摘 | Humphrey DM Emmanuel O Wilhellmus M | 2010 | Malaria Res Tr2010，10，9： | 1 |
| 14 | European multi-centre study of the Nucleus Hybrid L24 cochlear implant显示文摘 | Thomas Lenarz Chris James Domenico Cuda Alec Fitzgerald O&rsquo Connor Bruno Frachet Johan H.M. Frijns Thomas Klenzner Roland Laszig Manuel Manrique Mathieu Marx Paul Merkus Emmanuel A.M. Mylanus Erwin Offeciers Joerg Pesch Angel Ramos-Macias Alain Robier | 2013 | International Journal of Audiology2013，，12： | 1 |
| 15 | Assessment of Lactobacillus species colonizing the vagina of apparently healthy Nigerian woman,using PCR-DDGE and 16S rRNA gene sequencing显示文摘 | KINGSLEY C A EMMANUEL S O JEOM A | 2006 | World Journal of Microbiology and Biotechnology2006，22，： | 1 |
| 16 | An automated method for estima-ting reliability of grid systems using Bayesian networks显示文摘 | Doguc O Emmanuel R-M J | 2012 | Re-liability Engineering & System Sa/^j^2012，104，1： | 1 |
| 17 | Early tacrolimus exposure after liver transplantation: Relationship with moderate/severe acute rejection and long-term outcome显示文摘 | Manuel Rodríguez-Perálvarez Giacomo Germani Vasilios Papastergiou Emmanuel Tsochatzis Evangelos Thalassinos Tu Vinh Luong Nancy Rolando Amar Paul Dhillon David Patch James O’Beirne Douglas Thorburn Andrew Kenneth Burroughs | 2012 | Journal of Hepatology2012，，： | 1 |
| 18 | Relations between Back Muscles Endurance Capacity and Risk of Low-Back Pain显示文摘 | Emmanuel C Ayanniyi O | 2010 | TAF Pre- ventive Medicine Bulletin2010，9，5： | 1 |
| 19 | A 1H and 13CNMR spectral study of some 4-ac- yl-3-methyl-l-phenylpyrazol-5-ones in chloroform显示文摘 | Emmanuel C O | 1984 | Spectro- chimiea Acta Part A1984，40，5： | 1 |
| 20 | Silicene and transition metal based materials: prediction of a two-dimensionalpiezomagnet显示文摘 | Nelson Y Dzade Kingsley O Obodo Sampson K Adjokatse Akosa C Ashu Emmanuel Amankwah Clement D Atiso Abdulhakeem A Bello Emmanuel Igumbor Stany B Nzabarinda Joshua T Obodo Anthony O Ogbuu Olu Emmanuel Femi Josephine O Udeigwe Umesh V Waghmare | 2010 | Journal of Physics: Condensed Matter2010，，： | 1 |
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