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| 1 | Using old liver grafts for liver transplantation: Where are the limits?显示文摘The scarcity of ideal liver grafts for orthotopic liver transplantation(OLT) has led transplant teams to investigate other sources of grafts in order to augment the donor liver pool. One way to get more liver grafts is to use marginal donors, a not well-defined group which includes mainly donors > 60 years, donors with hypernatremia or macrosteatosis > 30%, donors with hepatitis C virus or hepatitis B virus positive serologies, cold ischemia time > 12 h, non-heart-beating donors, and grafts from split-livers or living-related donations. Perhaps the most practical and frequent measure to increase the liver pool, and thus to reduce waiting list mortality, is to use older livers. In the past years the results of OLT with old livers have improved, mainly due to better selection and maintenance of donors, improvements in surgical techniques in donors and recipients, and intra- and post-OLT management. At the present time, sexagenarian livers are generally accepted, but there still exists some controversy regarding the use of septuagenarian and octogenarian liver grafts. The aim of this paper is to briefly review the aging process of the liver and reported experiences using old livers for OLT. Fundamentally, the series of septuagenarian and octogenarian livers will be addressed to see if there is a limit to using these aged grafts. | Carlos Jiménez-Romero Oscar Caso Maestro Félix Cambra Molero Iago Justo Alonso Cristina Alegre Torrado Alejandro Manrique Municio Jorge Calvo Pulido Carmelo Loinaz Segurola Enrique Moreno González | 2014 | World Journal of Gastroenterology2014，20，31： | 11 |
| 2 | Oncotarget:新型免疫疗法药物组合或可有效治疗癌症显示文摘2016年6月21日,刊登于国际杂志《Oncotarget》上的一项研究论文中,来自梅奥诊所的研究人员通过研究开发了一种新型药物组合,可以增强机体免疫系统精确狙击杀灭癌细胞的能力,这种新型药物组合或许可以在治疗小鼠机体恶性癌症及转移性癌症上具有一定的治疗效应。 | Manrique SZ Dominguez AL Mirza N | 2016 | 疾病监测2016，31，7： | 2 |
| 3 | FT-IR spectroscopy as a tool for measuring degree of methyl esterification in pectins isolated from ripening papaya fruit显示文摘 | Guillermo D. Manrique Franco M. Lajolo | 2002 | Postharvest Biology and Technology2002，，1： | 2 |
| 4 | Influence of antiviral therapy in the long‐term outcome of recurrent hepatitis C virus infection following liver transplantation显示文摘 | A. García‐Reyne C. Lumbreras I. Fernández F. Colina M. Abradelo P. Magan R. San‐Juan A. Manrique F. López‐Medrano A. Fuertes M. Lizasoain E. Moreno J.M. Aguado | 2013 | Transpl Infect Dis2013，，4： | 2 |
| 5 | Do current anti-cyberloafing disciplinary practices have a replica in research findings?: A study of the effects of coercive strategies on workplace Internet misuse显示文摘 | Pablo Zoghbi Manrique de Lara Domingo Verano Tacoronte Jyh-Ming Ting Ding | 2006 | Internet Research2006，，4： | 2 |
| 6 | Fear in organizations: Does intimidation by formal punishment mediate the relationship between interactional justice and workplace internet deviance?显示文摘 | Pablo Zoghbi Manrique de Lara | 2006 | Journal of Managerial Psychology2006，，6： | 2 |
| 7 | The expanding role of oxidative stress, renin angiotensin system, and beta - cell dysfunction in the cardiometabolic syndrome and Type 2 diabetes mellitus 显示文摘 | Lastra G Manrique C | 2007 | Antioxid Redox Signal2007，9，7： | 1 |
| 8 | Severe nosocomial in-fection with imipenem-resistance Acinetobacter baumanniitreated with ampicilin/sulbactam显示文摘 | Levin AS Levy CE Manrique AE | 2003 | Int Antimicrob Agents2003，21，1： | 1 |
| 9 | Severe nosocomial infections with imipenem-resistance Acinetobacter baumannii treated with ampicillin/sulbactam显示文摘 | Levin AS Levy CE Manrique AE | | 0，，01： | 1 |
| 10 | High cardi- ovascular risk in patients with diabetes and the car- diometabolic syndrome: mandate for statin therapy 显示文摘 | Oonzalez GL Manrique CM Sowers JR | 2006 | J Cardiometab Syndr2006，1，3： | 1 |
| 11 | The renin angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative stress 显示文摘 | Manrique C Lastra G Gardner M | 2009 | Med Clin North Am2009，93，3： | 1 |
| 12 | Different stridulatory vibrations during sexual behavior and disturbance in the bloodsucking bug Triatoma infestans(Hemiptera:Reduviidae)显示文摘 | Roces F Manrique G | 2002 | J Insect Physiol2002，42，： | 1 |
| 13 | Preliminary Results of the Effect of Treatment of Hyperhomocysteinemia and Its Relationship With Inflammation, Coagulation Status, and Endothelial Function After Renal Transplantation显示文摘 | J. Manrique A. Diáz J.J. Gavira A. Hernández D. Pujante P. Errasti | 2005 | Transplantation Proceedings2005，，9： | 1 |
| 14 | Severe nosocomial infection with imipenem-resistant Acinetobacter baumannii treated with ampicillin/sulbactam显示文摘 | Levin AS Levy CE Manrique AE | 2003 | Int J Antimicrob Agents2003，21，1： | 1 |
| 15 | Registry of mild craniocerebral trauma:multicentre study from the Spanish Association of Pediatric Emergencies显示文摘 | García García JJ Manrique Martínez I Trenchs Sainz de la Maza V | 2009 | An Pediatr(Barc)2009，71，1： | 1 |
| 16 | Severe nosocomial infections with imipenem-resistant Acinetobacter baumannii treated with Ampicillin/sulbactam显示文摘 | Levin AS Levy CE Manrique AE | 2003 | Int J Antimicrob Agents2003，21，1： | 1 |
| 17 | Severe nosocomial in-fection with imipenem- resistance Acinetobacter baumannii treated with ampieilin/ sulbaetam 显示文摘 | Levin AS Levy CE Manrique AE | 2003 | Int J Antimieroh Agents2003，21，1： | 1 |
| 18 | Pharmacotherapeutic reviewand update of idiopathic nephrotic syndrome in children显示文摘 | Manrique RS Fernandez CM San JS | 2010 | PharmWorld Sci2010，32，3： | 1 |
| 19 | Kinetic analysis of the iron oxide reduction using hydrogen-carbon monoxide mixtures as reducing agent 显示文摘 | Bonatde A Henriquez A Manrique M | 2005 | ISIJ International2005，45，9： | 1 |
| 20 | , Rapid and sensitive allelespecific (AS)-RT-PCR assay for detection of T315I mutation in chronic myeloid leukemia patients treated with tyrosine-kinase inhibitors显示文摘 | Manrique AG Scholl V Perez V | 2011 | Clin Exp Med2011，11，1： | 1 |
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