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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus显示文摘 | BAYLISS C D PETERS R W COOK J K A | 1991 | Arch Virol1991，120，： | 1 |
| 3 | Effects of synthetic and naturally occurring flavonoids on metabolic activation of benzopyrene in hamster embryo cell cultures显示文摘 | CHAE Y H HO D K CASSADY J M COOK V M MARCUS C B BAIRD W M | 1992 | Chemico-biological Interactions1992，82，2： | 1 |
| 4 | Wind pollination in aquatic angiosperms 显示文摘 | Cook C D K | 1988 | Annals of the Missouri Botanical Garden1988，75，3： | 1 |
| 5 | Effects of chronic inhibition of GABA synthesis on attention and impulse control显示文摘 | PAINE T A COOKE E K LOWES D C | 2015 | Pharmacol Biochem Behav2015，135，： | 1 |
| 6 | Xenon purity analysis for exo-200 via mass spectrometry 显示文摘 | Dobi A Hall C Slutsky S Yen Y R Aharmin B Auger M Barbeau P S Benitez-Medina C Breidenbach M Cleveland B Conley R Cook J Cook S Counts I Craddock W Daniels T Davis C G Davis J Devoe R Dixit M Dolinski M J Donato K Fairbank Jr W Farine J Fierlinger P Franco D Giroux G Gornea R Graham K Gratta G Green C Hagemann C Hall K Hallman D Hargrove C Herrin S Hughes M Hodgson J Juget F Karelin A Kaufman L J Kuchenkov A Kumar K Leonard D S Lutter G Mackay D Maclellan R Marino M Mong B Montero Diez M Morgan P MUller A R Neilson R Odian A Oullivan K Piepke A Pocar A Prescott C Y Pushkin K Rivas A Rollin E Rowson P C Sabourov A Sinclair D Skarpaas K Stekhanov V Strickland V Swift M Twelker K Vuilleumier J L Vuilleumier J M Weber M Wichoski U Wodin J Wright J D Yang L | 2012 | Nuclear Instruments and Methods in Physics Research Section A: Accelerators Spectrometers Detectors and Associated Equipment2012，675，： | 1 |
| 7 | Behavioral and physiological assessment of low concentration of clove oil anaes- thetic for handing and transporting largemouth bass 显示文摘 | COOKE S J SUSKI C D OSTRAND K G | 2004 | Aqua- cuhure2004，239，： | 1 |
| 8 | A revision of the genus Hydrocharis (Hydrocharitaceae)显示文摘 | COOK C D K L/ )OND R | 1982 | Aquatic Botany1982，，14： | 1 |
| 9 | A recombinant fowlpox virus that expresss the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus 显示文摘 | Bayliss C D Peters R W Cook J K A | 1991 | Arch Virol1991，120，： | 1 |
| 10 | Empirical tests of the absolute sleeper effect predicted from the discounting cue hypothesis显示文摘 | GRUDER C L COOK T D HENNIGAN K M | 1978 | Journal of Personality and Social Psychology1978，36，： | 1 |
| 11 | Restaurant consumer acceptance of beef loin strip steaks tenderized with calcium chloride显示文摘 | Hoover L C Cook K D Miller M F | 1995 | J Anim Sci1995，73，： | 1 |
| 12 | Qnan-tification of several 4-alkyl substituted gamma-lactones inAustralian wines显示文摘 | Cooke R C Capone D L van Leeuwen K A | 2009 | Journal of Agricultural and FoodChemistry2009，57，2： | 1 |
| 13 | CO2-induced a- cidification affects hatching success in Calanus finmarchicus 显示文摘 | MAYOR D J MATTHEWS C COOK K | 2007 | Marine Ecology Progress Series2007，350，： | 1 |
| 14 | The impact of recalcitrant organic character on disinfection stability,trihalomethane formation and bacterial regrowth:an evaluation of magnetic ion exchange(MIEX) and alum coagulation显示文摘 | Drikas M Chow C W K Cook D | 2003 | Journal of Water Supply:Research and Technology2003，52，7： | 1 |
| 15 | Odor detection thresholds and enantiomeric distributions of several 4-alkyl substituted γ-lactones in Australian red wine显示文摘 | Cooke R C Leeuwen K A v Capone D L | | 0，，06： | 1 |
| 16 | Innovative calorimetric AC Loss measurement of HTSC for power applications显示文摘 | See K W Cook C D Dou S X | 2011 | IEEE Transactions on Applied Superconductivity2011，21，3： | 1 |
| 17 | A simple technique for detection of feeding in newly metamorphosed abalone显示文摘 | Burns D Cooke C A | 1986 | Aquac1986，51，： | 1 |
| 18 | A recombinant fowpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus显示文摘 | Bayliss C D Perters R W Cook J K A | 1991 | Archives of Virology1991，120，： | 1 |
| 19 | Ecosystem response ofpasture soil communities tofiimigation-induced microbial diversityreductions: an examination of thebiodiversity-ecosystemfunctionrelationship 显示文摘 | Griffiths B S Ritz K Bardgett R D Cook R Christensen S Ekelund F Sorensen SJ Baath E Bloen J de Ruiter P C DolfingJ Nicolardot B | 2000 | Oikos2000，90，2： | 1 |
| 20 | Scales for the measurement of innovativeness显示文摘 | HURT H T JOSEPH K COOK C D | 1977 | Human Communication Research1977，4，1： | 1 |
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