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| 1 | Association of time to prostate-specific antigen nadir and logarithm of prostate-specific antigen velocity after progression in metastatic prostate cancer with prior primary androgen deprivation therapy显示文摘我们与优先的主要雄激素剥夺治疗(ADT ) 在变形前列腺癌症在前进木头(PSAVAP ) 以后调查了前列腺特定的抗原天底(TTPN ) 和前列腺特定的抗原速度的对数的时间的协会。从 2000 ~ 2009 与主要 ADT 对待的所有变形前列腺癌症病人被考察。开发了疾病前进的病人在随后的分析被包括。病人们根据他们的 TTPN 被分成三个组:< 的 TTPN; 3 个月, 3-17 月,和 > 17 个月。我们用 Mann-Whitney U-test 和 Kruskal-Wallis 测试比较了在不同 TTPN 组之间的木头(PSAVAP ) 。木头(PSAVAP ) 上的进一步多重的线性回归分析被执行为使因素惊讶的另外的潜力调整。在与主要 ADT 被对待的 419 个病人之中, 306 个病人与 28 个月的中部的后续开发了疾病前进。更长的 TTPN 与更低的木头(PSAVAP ) 被联系(P = 0.008 ) 在所有亚群分析以内(< 的 TTPN; 3 对 3-17 月, P = 0.020;3-17 对 > 的 TTPN; 17 个月, P = 0.009;并且 < 的 TTPN; 3 对 > 17 个月, P = 0.001 ) 。在多重线性回归分析之上,基线 PSA (回归系数 0.001 , P = 0.045 ), PSA 天底(回归系数 0.002 , P = 0.040 ),并且 TTPN (回归系数 − ; 0.030 , P = 0.001 )是显著地与木头( PSAVAP )被联系的三个因素。在结论,更长的 TTPN 在跟随主要 ADT 的变形前列腺癌症病人与更低的木头(PSAVAP ) 被联系。在 3 个月和 17 个月的 TTPN cut-offs 看起来在预言木头(PSAVAP ) 有预示的意义。TTPN 可以在与疾病前进在病人决定治疗策略用作好预示的指示物。 | Jeremy YC Teoh James HL Tsu Steffi KK Yuen Peter KF Chiu Samson YS Chan Ka-Wing Wong Kwan-Lun Ho Simon SM Hou Chi-Fai Ng Ming-Kwong Yiu | 2017 | Asian Journal of Andrology2017，19，1： | 6 |
| 2 | A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension显示文摘 | King Sum Luk Christina Ip Meng-Qi GONG Sunny Hei WONG William KK Wu Mei DONG Guang-Ping LI Ka Pang Chan Yi-Mei DU Tong LIU Martin CS Wong David Shu Cheong Hui Gary Tse | 2017 | Journal of Geriatric Cardiology2017，14，12： | 5 |
| 3 | Outcome analysis of management of liver trauma: A 10-year experience at a trauma center显示文摘AIM: To review the outcomes of liver trauma in patients with hepatic injuries only and in patients with associated injuries outside the liver.METHODS: Data of liver trauma patients presented to our center from January 2003 to October 2013 were reviewed. The patients were divided into two groups. Group 1 consisted of patients who had hepatic injuries only. Group 2 consisted of patients who also had associated injuries outside the liver.RESULTS: Seven(30.4%) patients in group 1 and 10(28.6%) patients in group 2 received non-operative management; the rest underwent operation. Blunt trauma occurred in 82.8%(48/58) of the patients and penetrative trauma in 17.2%(10/58). A higher injury severity score(ISS) was observed in group 2(median 45 vs 25, P < 0.0001). More patients in group 1 were hemodynamically stable(65.2% vs 37.1%, P = 0.036). Other parameters were comparable between groups. Group 1 had better 30-d survival(91.3% vs 71.4%, P = 0.045). On multivariate analysis using the logistic regression model, ISS was found to be associated with mortality(P = 0.004, hazard ratio = 1.035, 95%CI:CONCLUSION: Liver trauma patients with multiple injuries are relatively unstable on presentation. Despite a higher ISS in group 2, non-operative management was possible for selected patients. Associated injuries outside the liver usually account for morbidity and mortality. | Wong Hoi She Tan To Cheung Wing Chiu Dai Simon HY Tsang Albert CY Chan Daniel KH Tong Gilberto KK Leung Chung Mau Lo | 2016 | World Journal of Hepatology2016，8，15： | 3 |
| 4 | The development of the Chinese version of impact of event scalerevised(CIES-R)显示文摘 | Wu KK Chan KS | 2003 | Soc Psychiatry and Psychiatr Epidemiol2003，38，2： | 1 |
| 5 | Posteromedial tibial plateau injury including avulsion fracture of the semimembranous tendon insertion site:ancillary sign of anterior cruciate ligament tear at MR imaging显示文摘 | Chan KK Resnick D Goodwin D | 1999 | Radiology1999，211，3： | 1 |
| 6 | Bcl-2andp53protein expression,apoptosis and p53 mutation inhuman epithelial ovarian cancers显示文摘 | Chan WY Cheung KK Schorge JO | 2000 | Am J Pathol2000，156，： | 1 |
| 7 | Volar fixation of dorsally displaced distal radial fracture using locking compression plate显示文摘 | Wong KK Chan KW Kwok TK | | 0，，： | 1 |
| 8 | Co-localization of NMDA receptors and AMPA receptors in the neurons of vestibular nuclei of rats 显示文摘 | Chen LW Yung KK Chan YS | 2000 | Brain Res2000，884，12： | 1 |
| 9 | A combination of chemoirradiation and chemotherapy for treatment of advanced clear cell adenocarcinoma of the cervix 显示文摘 | Chan KK Ip P Kwong P | 2008 | Int J Gynecol Cancer2008，18，3： | 1 |
| 10 | Gas chromatography mass spectrometry in metabolic profiling of biological fluids显示文摘 | Pasikanti KK Ho PC Chan EC | 2008 | J Chromatogr B Analyt Technol Biomed Life Sci2008，871，2： | 1 |
| 11 | Host genes and influenzapathogenesis in humans: an emerging paradigm显示文摘 | To KK Zhou J Chan JF | 2015 | CurrOpin Virol2015，14，： | 1 |
| 12 | Volar fixation of dorsally displaced distal radial fracture using locking compression plate显示文摘 | Wong KK Chan KW Kwok TK | 2005 | J Orthop Surg (Hong Kong)2005，13，15： | 1 |
| 13 | Phase I and pharrnacologic evaluation of intraperitoneal 5-fluoro-2'-deoxyuridine 显示文摘 | Muggia FM Chan KK Russell C | 1991 | Cancer Chemother Pharmacol1991，28，： | 1 |
| 14 | Vaginal vault dehiscence after laparoscopic hysterectomy over a nine-year period at Sydney West Advanced Pelvic Surgery Unit-Our experiences and current understanding of vaginal vault dehiscence显示文摘 | Chan WS Kong KK Nikam YA | 2012 | Aust N Z J Obstet Gynecol2012，52，2： | 1 |
| 15 | Vo la r fix a tio no f do rsally displaced distal radial fracture using locking compression plate显示文摘 | Wong KK Chan KW Kw ok TK | 2005 | J Ortho p Surg (Hong Kong)2005，13，2： | 1 |
| 16 | 20-year experience of managing profuse bleeding in gestational tropboblastic disease 显示文摘 | Tse KY Chan KK Tam KF | 2007 | J Reprod Med2007，52，5： | 1 |
| 17 | Bcl-2 and p53 Protein Expression,Apoptosis,and p53 Mutation in Human Epithelial Ovarian Cancers显示文摘 | Chan WY Cheung KK Schorge JO | 2000 | Am J Pathol2000，156，： | 1 |
| 18 | DOC-2,a candidate tumor suppressor gene in human epithelial ovarian cancer显示文摘 | Mok SC Chan WY Wong KK | 1998 | Oncogene1998，16，18： | 1 |
| 19 | Interaction of the heart-specific LIM domain protein,FHL2,with DNA-binding nuclear protein,hNP220显示文摘 | Ng EK Chan KK Wong CH | 2002 | J Cell Biochem2002，84，3： | 1 |
| 20 | Evaluation of a newly developed genoarray human papillomavirus(HPV) geno- typing assay and comparison With the roche linear array HPV genotyping assay显示文摘 | Liu SS Leung RC Chan KK | 2010 | J Clin Microbiol2010，48，3： | 1 |
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