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529篇 您的检索式：作者名="Chan KS"

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	题名	作者	年代	出处	被引量
1	Polymethylmethacrylate bone cements and additives: A review of the literature显示文摘Polymethylmethacrylate(PMMA) bone cement technology has progressed from industrial Plexiglass administration in the 1950 s to the recent advent of nanoparticle additives. Additives have been trialed to address problems with modern bone cements such as the loosening of prosthesis, high post-operative infection rates, and inflammatory reduction in interface integrity. This review aims to assess current additives used in PMMA bone cements and offer an insight regarding future directions for this biomaterial. Low index(< 15%) vitamin E and low index(< 5 g) antibiotic impregnated additives significantly address infection and inflammatory problems, with only modest reductions in mechanical strength. Chitosan(15% w/w PMMA) and silver(1% w/w PMMA) nanoparticles have strong antibacterial activity with no significant reduction in mechanical strength. Future work on PMMA bone cements should focus on trialing combinations of these additives as this may enhance favourable properties.	Manit Arora Edward KS Chan Sunil Gupta Ashish D Diwan	2013	World Journal of Orthopedics2013，4，2：	10
2	Mutations around interferon sensitivity-determining region:A pilot resistance report of hepatitis C virus 1b in a Hong Kong population显示文摘AIM: To explore mutations around the interferon sensitivity-determining region (ISDR) which are associated with the resistance of hepatitis C virus 1b (HCV-1b) to interferon-α treatment. METHODS: Thirty-seven HCV-1b samples were ob- tained from Hong Kong patients who had completed the combined interferon-α/ribavirin treatment for more than one year with available response data. Nineteen of them were sustained virological responders, while 18 were non-responders. The amino acid sequences of the extended ISDR (eISDR) covering 64 amino acids upstream and 67 amino acids downstream from the previously reported ISDR were analyzed. RESULTS: One amino acid variation (I2268V, P = 0.023) was significantly correlated with treatment outcomein this pilot study with a limited number of patients, while two amino acid variations (R2260H, P = 0.05 and S2278T, P = 0.05) were weakly associated with treatment outcome. The extent of amino acid variations within the ISDR or eISDR was not correlated with treatment outcome as previously reported. CONCLUSION: Three amino acid mutations near but outside of ISDR may associate with interferon treatment resistance of HCV-1b patients in Hong Kong.	Xiao-Ming Zhou Paul KS Chan John S Tam	2011	World Journal of Gastroenterology2011，17，48：	3
3	Use of transcranial Doppler to predict outcome in patiens with intracranial large-artery occlusive disease 显示文摘	Wong KS Li H Chan YL	2000	Stroke2000，31，11：	1
4	The development of the Chinese version of impact of event scalerevised(CIES-R)显示文摘	Wu KK Chan KS	2003	Soc Psychiatry and Psychiatr Epidemiol2003，38，2：	1
5	MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells 显示文摘	Chan JA Krichevsky AM Kosik KS	2005	Cancer Res2005，65，14：	1
6	Signal transducer and activator of transcription 3 (Stat3) in epithelial carcinogenesis显示文摘	Kim DJ Chan KS Sano S	2007	Mol Carcinog2007，46，8：	1
7	MicroRNA-21 is anantiapoptotic factor in human glioblastoma cells显示文摘	Chan JA Krichevsky AM Kosik KS	2005	Can- cer Res2005，65，14：	1
8	Impact of antiviral therapy on the survival of patients after major hepatectomy for hepatitis B virus-related hepatocellular carcinoma显示文摘	Chan AC Chok KS Yuen WK	2011	Arch Surg2011，146，6：	1
9	Adiponectin is pro-tective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicity显示文摘	CHAN KH LAM KS CHENG OY	2012	Plos One2012，7，12：	1
10	MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells 显示文摘	Chan JA Krichevsky AM Kosik KS	2005	Cancer Res2005，65，14：	1
11	Mechanisms of acute cerebral infarctions in patients with middle cerebral artery stenosis: a diffusion-weighted imaging and microemboli monitoring study 显示文摘	Wong KS Gao S Chan YL	2002	Ann Neuro12002，52，1：	1
12	MicroRNA-21 is an antiapop- totic factor in human glioblastoma cells 显示文摘	Chan JA Krichevsky AM Kosik KS	2005	Cancer Res2005，65，14：	1
13	SARS: prognosis, outcome and sequelae显示文摘	Chan KS Zheng JP Mok YW	2003	Respirology2003，，：	1
14	Cancer stem cells in bladdercancer: a revisited and evolving concept 显示文摘	Chan KS Volkmer JP Weissman I	2010	Curr Opin Urol2010，20，5：	1
15	Effects of a single session of whole body vibrationon ankle plantarflexion spasticity and gait performance inpatients with chronic stroke: a randomized controlled trial显示文摘	Chan KS Liu CW Chen TW	2012	Clinical Rehabil- itation2012，26，13：	1
16	Progression of middle cerebral artery occlusive disease and its relationship with further vascular events after stroke显示文摘	Wong KS Lam WW Chan YL	2002	Stroke2002，33，2：	1
17	MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells 显示文摘	Chan JA Krichevsky AM Kosik KS	2005	Cancer Res2005，65，：	1
18	Use of transcranial Doppler ultrasound to predict outcome in patients with intracranial large-artery occlusive di- sease显示文摘	Wong KS Li H Chan YL	2000	Stroke2000，31，11：	1
19	MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells显示文摘	Chan JA Krichevsky AM Kosik KS	2005	Cancer Res2005，65，14：	1
20	Signal transducer and activator of transcription3(Stat3) in epithelial carcinogenesis显示文摘	Kim DJ Chan KS Sano S	2007	Mol Carcinoq2007，46，8：	1

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