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| 1 | Comparison of pediatric and adult antibiotic-associated diarrhea and Clostridium difficile infections显示文摘Antibiotic-associated diarrhea(AAD) and Clostridum difficile infections(CDI) have been well studied for adult cases, but not as well in the pediatric population. Whether the disease process or response to treatments differs between pediatric and adult patients is an important clinical concern when following global guidelines based largely on adult patients. A systematic review of the literature using databases Pub Med(June 3, 1978-2015) was conducted to compare AAD and CDI in pediatric and adult populations and determine significant differences and similarities that might impact clinical decisions. In general, pediatric AAD and CDI have a more rapid onset of symptoms, a shorter duration of disease and fewer CDI complications(required surgeries and extended hospitalizations) than in adults. Children experience more community-associated CDI and are associated with smaller outbreaks than adult cases of CDI. The ribotype NAP1/027/BI is more common in adults than children. Children and adults share some similar risk factors, but adults have more complex risk factor profiles associated with more co-morbidities, types of disruptive factors and a wider range of exposures to C. difficile in the healthcare environment. The treatment of pediatric and adult AAD is similar(discontinuing or switching the inciting antibiotic), but other treatment strategies for AAD have not been established. Pediatric CDI responds better to metronidazole, while adult CDI responds better to vancomycin. Recurrent CDI is not commonly reported for children. Prevention for both pediatric and adult AAD and CDI relies upon integrated infection control programs, antibiotic stewardship and may include the use of adjunctive probiotics. Clinical presentation of pediatric AAD and CDI are different than adult AAD and CDI symptoms. These differences should be taken into account when rating severity of disease and prescribing antibiotics. | Lynne Vernice Mc Farland Metehan Ozen Ener Cagri Dinleyici Shan Goh | 2016 | World Journal of Gastroenterology2016，22，11： | 39 |
| 2 | 隧道排水诱发地下水位下降对地表植被影响的TSPAC分析方法显示文摘山岭隧道建设可能会改变周边地下水渗流场,严重时会疏干地下水,威胁地表植被生存。针对现有研究难以定量分析隧道排水对地表植被影响的问题,提出以土壤水基质势作为植被生存状态指标,建立隧道-土壤-植被-大气连续体(tunnelsoil-plant-atmosphere continuum,TSPAC)分析模型。通过Richards方程描述植被根系区的土壤水分运移,将大气、地下水渗流模型作为上下边界输入方程,计算植被根系区基质势分布,据此衡量植被凋萎过程并判断其生存状态。将该分析方法应用于大别山区明堂山隧道工程,分析隧道建设对地表植被的影响,结果表明:(1)植被根系区土壤水基质势对地下水位和大气变化的响应存在滞后性和非均匀性,植被凋萎是渐进、动态的过程;(2)大气条件在该区域对植被生存起控制性作用;(3)隧道建设引起的地下水位变化对周边地表植被影响较小,且对不同植被类型影响程度不一。TSPAC分析方法的创新性在于:提出了物理概念明确、易于工程使用的植被生态危险状态判断指标与依据,在SPAC分析模型基础上引入隧道地下水渗流模型,将隧道排水的工程因素与环境因素相结合,分析隧道排水—地下水位下降—地表植被影响的整体过程,并在实际工程中进行应用,可为隧道建设的环境保护提供一种新思路。 | 李晓军 徐昊 Gokdemir Cagri 王飞 黄学文 | 2020 | 隧道建设(中英文)2020，40，9： | 3 |
| 3 | Improved Viability of Random Pattern Skin Flaps through the Use of Adipose-Derived Stem Cells显示文摘 | Feng Lu Hiroshi Mizuno Cagri A. Uysal Xiaobo Cai Rei Ogawa Hiko Hyakusoku | 2008 | Plastic and Reconstructive Surgery2008，，： | 2 |
| 4 | The Effect of Adipose-Derived Stem Cells on Ischemia-Reperfusion Injury: Immunohistochemical and Ultrastructural Evaluation显示文摘 | A Cagri Uysal Hiroshi Mizuno Morikuni Tobita Rei Ogawa Hiko Hyakusoku | 2009 | Plastic and Reconstructive Surgery2009，，： | 2 |
| 5 | Coordinated Replenishment Strategies in Inventory/Distribution Systems显示文摘 | Mustafa Cagri Gurbuz Kamran Moinzadeh Yong-Pin Zhou | 2007 | Management Science2007，53，2： | 1 |
| 6 | Effect of diameter in predicting the elastic properties of 2D braided tubular composites显示文摘 | AYRANCI Cagri CAREY Jason P | 2010 | Composite Materials2010，44，16： | 1 |
| 7 | Rational antibiotic use and academic staff显示文摘 | Cagri BA Ermertcan S Hosgor-Limoncu M | 2003 | Int J Antimicrob Agents2003，21，1： | 1 |
| 8 | Saccharomyces boulardii CNCM I-745 in different clinical conditions显示文摘 | Ener Cagri Dinleyici Ates Kara Metehan Ozen Yvan Vandenplas | 2014 | Expert Opinion on Biological Therapy2014，，11： | 1 |
| 9 | Pentoxifylline inhibits overflow and reduces intestinal reperfusion injury显示文摘 | Cagri S Tülin A Murat C | 1997 | J Pedia Sury1997，32，6： | 1 |
| 10 | Satellite image con- trast enhancement using discrete wavelet transform and sin- gular value decomposition 显示文摘 | HASAN DEMIREL CAGRI OZCINAR | 2010 | IEEE Geoscience And Re- mote Sensing Letters2010，7，2： | 1 |
| 11 | Squamous cell carcinoma ofthe auricle arising from keloid after radium neddie therapy显示文摘 | Mizuno H Cagri UA Koike S | 2006 | J Craniofac Surg2006，17，2： | 1 |
| 12 | Predicting Stripping and Moisture Induced Damage of Asphalt Concrete Prepared with Polymer Modified Bitumen and Hydrated Lime 显示文摘 | Gorkem Cagri Sengoz Burak | 2009 | Construction and Building Materials2009，23，6： | 1 |
| 13 | The Effects of Organizational Training on Organizational Commitment显示文摘 | CAGRI O | 2010 | International Jour- nal of Training and Development2010，14，4： | 1 |
| 14 | Ceftriaxone-associated biliary sludge and pseudocholelithiasis during child- hood : A prospective study显示文摘 | Ozcan Bor Ener Cagri Dinleyici Mahmut Kebapci | 2004 | Pediatr Int2004，46，3： | 1 |
| 15 | A preliminary evaluation of the distance English lan- guage teacher training program (DELq:FP) in Anadolu University, Turkey 显示文摘 | CAGRI O B | 2007 | Turkish Online Journal of Distance Education2007，，8： | 1 |
| 16 | Effects of 0.2% chlorhexidine gluconate and amoxicillin plus clavulanic acid on the prevention of alveolar osteitis following mandibular third molar extractions显示文摘 | Cagri Delilbasi Umut Saracoglu Ahmet Keskin | 2002 | Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology2002，，3： | 1 |
| 17 | Minimization of chemicals use during adsorptive recovery of suceinic acid显示文摘 | Cagri Efe Mervin Pieterse Horge Gascon Freek Kapteijn Luuk A M van der Wielen Adrie J J Straathof | 2010 | Industrial and Engineering Chemistry Research2010，49，： | 1 |
| 18 | Antimicrobial, mechanical, and moisture barrier properties of low pH whey protein-based edible films containing β-aminobenzoic or sorbic acids显示文摘 | CAGRI A USTUNOL Z RYSER E T | 2006 | Journal of Food Science2006，66，6： | 1 |
| 19 | Comment on 'Unit approach for vermilion repair in unilateral cleft surgery'by onishi and maruyama显示文摘 | Cihat N Baran Cagri Uysal Namik K Baran | 2003 | Euro J Plast Surg2003，26，4： | 1 |
| 20 | Effects of granulocyte-colony stimulating factor on peritoneal defense mechanisms and bacterial translocation after administration of systemic chemotherapy in rats显示文摘AIM: To investigate the effects of granulocyte-colony stimulating factor (G-CSF) on peritoneal defense mechanisms and bacterial translocation after systemic 5-Fluorouracil (5-FU) administration. METHODS: Thirty Wistar albino rats were divided into three groups; the control, 5-FU and 5-FU + G-CSF groups. We measured bactericidal activity of the peritoneal fluid, phagocytic activity of polymorphonuclear leucocytes in the peritoneal fluid, total peritoneal cell counts and cell types of peritoneal washing fluid. Bacterial translocation was quantified by mesenteric lymph node, liver and spleen tissue cultures. RESULTS: Systemic 5-FU reduced total peritoneal cell counts, neutrophils and macrophage numbers. It also altered bactericidal activity of the peritoneal fluid and phagocytic activity of polymorphonuclear leucocytes in the peritoneal fluid. 5-FU also caused significant increase in frequencies of bacterial translocation at the liver and mesenteric lymph nodes. G-CSF decreased bacterial translocation, it significantly enhanced bactericidal activity of the peritoneal fluid and phagocytic activity of polymorphonuclear leucocytes in the peritoneal fluid. It also increased total peritoneal cell counts, neutrophils and macrophage numbers. CONCLUSION: Systemic 5-FU administration caused bacterial translocation, decreased the bactericidalactivity of peritoneal fluid and phagocytic activity of polymorphonuclear leucocytes in the peritoneal fluid. G-CSF increased both bactericidal activity of the peritoneal fluid and phagocytic activity of polymorphonuclear leucocytes in the peritoneal fluid, and prevented the bacterial translocation. We conclude that intraperitoneal GCSF administration protects the effects of systemic 5-FU on peritoneal defense mechanisms. | Celal Cerci Cagri Ergin Erol Eroglu Canan Agalar Fatih Agalar Sureyya Cerci Mahmut Bulbul | 2007 | World Journal of Gastroenterology2007，13，18： | 1 |
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