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| 1 | Sodium Stress in the Halophyte Thellungiella halophila and Transcriptional Changes in a thsos1-RNA Interference Line显示文摘The plasma membrane Na^+/H^+-antiporter salt overly sensitive1(SOS1)from the halophytic Arabidopsis-relative Thel-lungiella halophila(ThSOS1)shows conserved sequence and domain structure with the orthologous genes fromArabidopsis thaliana and other plants.When expression of ThSOS1 was reduced by RNA interference(RNAi),pronouncedcharacteristics of salt-sensitivity were observed.We were interested in monitoring altered transcriptional responsesbetween Thellungiella wild type and thsosl-4,a representative RNAi line with particular emphasis on root responses to saltstress at 350 mmol/L NaCl,a concentration that is only moderately stressful for mature wild type plants.Transcript profilingrevealed several functional categories of genes that were differently affected in wild-type and RNAi plants.Down-regulationof SOS1 resulted in different gene expression even in the absence of stress.The pattern of gene induction in the RNAi plantunder salt stress was similar to that of glycophytic Arabidopsis rather than that of wild type Thellungiella.The RNAi plantsfailed to down-regulate functions that are normally reduced in wild type Thellungiella upon stress and did not up-regulatefunctions that characterize the Thellungiella salt stress response.Metabolite changes observed in wild type Thellungiellaafter salt stress were less pronounced or absent in RNAi plants.Transcript and metabolite behavior suggested SOS1functions including but also extending its established function as a sodium transporter.The down-regulation of ThSOS1converted the halophyte Thellungiella into a salt-sensitive plant. | Dong-Ha Oh Qingqiu Gong Alex Ulanov Quan Zhang Youzhi Li Wenying Ma Dae-Jin Yun Ray A. Bressan Hans J. Bohnert | 2007 | Journal of Integrative Plant Biology2007，49，10： | 9 |
| 2 | Healing time of incision infection after hepatobiliary surgery treated by needle-free incision suture closure显示文摘AIM:To compare the effectiveness of needle-free incision suture closure with butterfly tape and traditional secondary suturing techniques in treating incision infection.METHODS:Two hundred and twenty-three patients with incision infection following hepatobiliary surgery at a tertiary hospital were randomly divided into three groups:90 patients were closed by needle-free incision suture closure,which gradually closed the incision wound when drainage from incision infection was visibly decreased and healthy granulation tissues had grown;79 patients were closed by butterfly bandage;another 54 patients were closed by traditional secondary suturing technique.Healing time of incision infection was calculated from the beginning of dressing change to the healing of the incision.RESULTS:Healing time in the needle-free incision suture closure group(24.2±7.2 d)was significantly shorter than that in the butterfly bandage group(33.3±11.2 d)and the traditional secondary suturing group(36.2±15.3 d)(P<0.05).Healing time in the butterfly bandage group appeared to be slightly shorter than that in the secondary suture group,but the difference was not statistically significant(P>0.05).CONCLUSION:Needle-free incision suture closure could gradually close the infection wound at the same time of drainage and dressing change,thereby shortening the healing time. | Wen-Jie Ma Yong Zhou Hui Mao Rui-Hua Xu Anuj Shrestha Fu-Yu Li Alex Lorance Qin Yang Yong-Qiong Zhang Ting Jiang Huan Feng Wei Zhang Nan-Sheng Cheng | 2014 | World Journal of Gastroenterology2014，20，42： | 8 |
| 3 | Formulation Development and Antitumor Activity of a Filter-Sterilizable Emulsion of Paclitaxel显示文摘 | Panayiotis P. Constantinides Karel J. Lambert Alex K. Tustian Brian Schneider Salima Lalji Wenwen Ma Bryan Wentzel Dean Kessler Dilip Worah Steven C. Quay | 2000 | Pharmaceutical Research2000，，2： | 2 |
| 4 | Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo显示文摘 | Huanjie Shao Chun Gao Haikuo Tang Hao Zhang Lewis R. Roberts Bonnie L. Hylander Elizabeth A. Repasky Wen W. Ma Jingxin Qiu Alex A. Adjei Grace K. Dy Chunrong Yu | 2011 | Journal of Hepatology2011，，1： | 2 |
| 5 | Esophageal varices on computed tomography and subsequent variceal hemorrhage显示文摘 | Ma Somsouk Katherine To’o Mujtaba Ali Eric Vittinghoff Benjamin M. Yeh Judy Yee Alex Monto John M. Inadomi Rizwan Aslam | 2014 | Abdominal Imaging2014，，2： | 1 |
| 6 | Signature microRNA Expression Profile of Essential Hypertension and Its Novel Link to Human Cytomegalovirus Infection显示文摘 | Shuqiang Li Jianguo Zhu Weili Zhang Youren Chen Ke Zhang Laurentiu M. Popescu Xinliang Ma Wayne Bond Lau Rong Rong Xueqing Yu Bingbing Wang Yafeng Li Chuanshi Xiao Mingming Zhang Shuyan Wang Liping Yu Alex F. Chen Xinchun Yang Jun Cai | 2011 | Circulation2011，，： | 1 |
| 7 | Characterization of Vascular Injury Responses to Stent Insertion in an Ex-vivo Arterial Perfusion Model显示文摘 | Niharika Kamat Kim Lien-Thi Nguyen-Ehrenreich Steven H. Hsu Alex P. Ma Irene Sinn Leslie Coleman Julie Tai | 2011 | Journal of Vascular and Interventional Radiology2011，，2： | 1 |
| 8 | Approaching 19%efficiency and stable binary polymer solar cells enabled by a solidification strategy of solvent additive显示文摘Additives play a crucial role in enhancing the photovoltaic performance of polymer solar cells(PSCs).However,the typical additives used to optimize blend morphology of PSCs are still high boiling-point solvents,while their trace residues may reduce device stability.Herein,an effective strategy of“solidification of solvent additive(SSA)”has been developed to convert additive from liquid to solid,by introducing a covalent bond into low-cost solvent diphenyl sulfide(DPS)to synthesize solid dibenzothiophene(DBT)in one-step,which achieves optimized morphology thus promoting efficiency and device stability.Owing to the fine planarity and volatilization of DBT,the DBT-processed films achieve ordered molecular crystallinity and suitable phase separation compared to the additive-free or DPS-treated ones.Importantly,the DBT-processed device also possesses improved light absorption,enhanced charge transport,and thus a champion efficiency of 17.9%is achieved in the PM6:Y6-based PSCs with an excellent additive component tolerance,reproducibility,and stability.Additionally,the DBT-processed PM6:L8-BO-based PSCs are further fabricated to study the universality of SSA strategy,offering an impressive efficiency approaching19%as one of the highest values in binary PSCs.In conclusion,this article developed a promising strategy named SSA to boost efficiency and improve stability of PSCs. | Manjun Xiao Longfei Liu Yongdie Meng Baobing Fan Wenyan Su Conggui Jin Luocheng Liao Fan Yi Chao Xu Rui Zhang Alex K.-Y.Jen Wei Ma Qunping Fan | 2023 | Science China Chemistry2023，66，5： | 1 |
| 9 | Polymer-based optical waveguides : materials processing and devices 显示文摘 | Hong MA Alex K Y Jen Larry R Dalton | 2002 | 14(19) :1339 - 13652002，14，19： | 1 |
| 10 | Rosiglitazone and fenofibrate improve insulin sensitivity of pre-diabetic OLETF rats by reducing malonyl-CoA levels in the liver and skeletal muscle显示文摘 | Zhengshan Zhao Yong-Jik Lee Soo-Kyung Kim Hae-Jin Kim Wan-Sub Shim Chul-Woo Ahn Hyun-Chul Lee Bong-Soo Cha Zhongmin Alex Ma | 2009 | Life Sciences2009，，19： | 1 |
| 11 | Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo显示文摘 | Huanjie Shao Chun Gao Haikuo Tang Hao Zhang Lewis R. Roberts Bonnie L. Hylander Elizabeth A. Repasky Wen W. Ma Jingxin Qiu Alex A. Adjei Grace K. Dy Chunrong Yu | 2011 | Journal of Hepatology2011，，1： | 1 |
| 12 | A new perspective to develop regiorandom polymer acceptors with high active layer ductility,excellent device stability,and high efficiency approaching 17%显示文摘The recently reported efficient polymerized small-molecule acceptors(PSMAs)usually adopt a regioregular backbone by polymerizing small-molecule acceptors precursors with a low-reactivity 5-brominated 3-(dicyanomethylidene)indan-1-one(IC)end group or its derivatives,leading to low molecular weight,and thus reduce active layer mechanical properties.Herein,a series of newly designed chlorinated PSMAs originating from isomeric IC end groups are developed by adjusting chlorinated positions and copolymerized sites on end groups to achieve high molecular weight,favorable intermolecular interaction,and improved physicochemical properties.Compared with regioregular PY2Se-Cl-o and PY2Se-Cl-m,regiorandom PY2Se-Cl-ran has a similar absorption profile,moderate lowest unoccupied molecular orbital level,and favorable intermolecular packing and crystallization properties.Moreover,the binary PM6:PY2Se-Cl-ran blend achieves better ductility with a crack-onset strain of 17.5% and improved power conversion efficiency(PCE)of 16.23% in all-polymer solar cells(all-PSCs)due to the higher molecular weight of PY2Se-Cl-ran and optimized blend morphology,while the ternary PM6:J71:PY2Se-Cl-ran blend offers an impressive PCE approaching 17% and excellent device stability,which are all crucial for potential practical applications of all-PSCs in wearable electronics.To date,the efficiency of 16.86% is the highest value reported for the regiorandom PSMAs-based all-PSCs and is also one of the best values reported for the all-PSCs.Our work provides a new perspective to develop efficient all-PSCs,with all high active layer ductility,impressive PCE,and excellent device stability,towards practical applications. | Qunping Fan Ruijie Ma Wenyan Su Qinglian Zhu Zhenghui Luo Kai Chen Yabing Tang Francis RLin Yuxiang Li He Yan Chuluo Yang Alex K.-Y.Jen Wei Ma | 2023 | Carbon Energy2023，5，2： | 0 |
| 13 | Selenium-fused Y6 derivatives and their derived polymerized small molecule acceptors for efficient organic solar cells显示文摘Before 2015,only few organic solar cells(OSCs)obtained power conversion efficiencies(PCEs)over 10%because the commonly used fullerene derivatives as acceptors have narrow absorption,low extinction coefficient,and are difficult to adjust energy levels.To overcome these shortcomings,in 2015,Zhan et al.[1]developed acceptor(A)-donor(D)-A-type fused-ring small-molecule acceptors(SMAs)with good planarity and strong intramolecular charge transfer(ICT)effect to fulfill both broad absorption and high extinction coefficient,offering the revolutionary PCEs of 13%–15%.In 2019,another milestone SMA(Y6)with A-DA′D-A structure was developed by Zou et al. | Qunping Fan Francis RLin Wei Ma Alex K.-Y.Jen | 2023 | Science China Chemistry2023，66，3： | 0 |
| 14 | 也谈男女显示文摘面积:68平方米(建筑面积)间隔:二室二厅男女男女之间,除了身体结构外,心理以至思维,都反映两者极度的差异。当生活小节还停留在无选择的年代, | Alex Ma 黄浩然 庄诗雅 | 1998 | 城市住宅1998，，9： | 0 |
| 15 | Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic显示文摘Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were reported.The study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines.Methods We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke centres.Patients with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,codes.The 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May 2020.The prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal variation.Findings There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,p<0.0001).Embolisation of ruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative drop.Subgroup analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,p<0.0001).A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this tertile.Interpretation There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 pandemic.These findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction. | Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera James E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong Robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee Roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon John Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters Johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sugimura Masaaki Uno Yohei Takenobu Yuji Matsumaru Satoshi Yamada Ryuhei Kono Takuya Kanamaru Masafumi Morimoto Junichi Iida Vasu Saini Dileep Yavagal Saif Bushnaq Wenguo Huang Italo Linfante Jawad Kirmani David S Liebeskind Viktor Szeder Ruchir Shah Thomas G Devlin Lee Birnbaum Jun Luo Anchalee Churojana Hesham E Masoud Carlos Ynigo Lopez Brendan Steinfort Alice Ma Ameer E Hassan Amal Al Hashmi Mollie McDermott Maxim Mokin Alex Chebl Odysseas Kargiotis Georgios Tsivgoulis Jane G Morris Clifford J Eskey Jesse Thon Leticia Rebello Dorothea Altschul Oriana Cornett Varsha Singh Jeyaraj Pandian Anirudh Kulkarni Pablo M Lavados Veronica V Olavarria Kenichi Todo Yuki Yamamoto Gisele Sampaio Silva Serdar Geyik Jasmine Johann Sumeet Multani Artem Kaliaev Kazutaka Sonoda Hiroyuki Hashimoto Adel Alhazzani David Y Chung Stephan A Mayer Johanna T Fifi Michael D Hill Hao Zhang Zhengzhou Yuan Xianjin Shang Alicia C Castonguay Rishi Gupta Tudor G Jovin Jean Raymond Osama O Zaidat Raul G Nogueira SVIN COVID-19 Registry,the Middle East North Africa Stroke and Interventional Neurotherapies Organization(MENA-SINO),Japanese Society of Vascular and Interventional Neurology Society(JVIN) | 2021 | Stroke & Vascular Neurology2021，6，4： | 0 |
| 16 | Natural interploidy hybridization among the key taxa involved in the origin of horticultural chrysanthemums显示文摘Understanding hybridization and introgression between natural plant populations can give important insights into the origins of cultivated species. Recent studies suggest differences in ploidy might not create such strong reproductive barriers as once thought, and thus studies into cultivated origins should examine all co-occurring taxa, including those with contrasting ploidy levels. Here, we characterized hybridization between Chrysanthemum indicum L., Chrysanthemum vestitum (Hemsley) Ling and Chrysanthemum vestitum var. latifolium (Zhou & Chen), the most important wild species involved in the origins of cultivated chrysanthemums. We analyzed the population structure of 317 Chrysanthemum accessions based on 13 microsatellite markers and sequenced chloroplast trnL-trnF for a subset of 103 Chrysanthemum accessions. We identified three distinct genetic clusters, corresponding to the three taxa. We detected 20 hybrids between species of different ploidy levels, of which 19 were between C. indicum (4x) and C. vestitum (6x) and one was between C. indicum and C. vestitum var. latifolium (6x). Fourteen hybrids between C. indicum and C. vestitum were from one of the five study sites. Chrysanthemum vestitum and C. vestitum var. latifolium share only one chloroplast haplotype. The substantially different number of hybrids between hybridizing species was likely due to different levels of reproductive isolation coupled with environmental selection against hybrids. In addition, human activities could play a role in the different patterns of hybridization among populations. | Shuai Qi Alex D.Twyford Jun-Yi Ding James SBorrell Long-Zhen Wang Yue Ping Ma Nian Wang | 2022 | Journal of Systematics and Evolution2022，60，6： | 0 |
| 17 | Database Commons:A Catalog of Worldwide Biological Databases显示文摘Biological databases serve as a global fundamental infrastructure for the worldwide scientific community,which dramatically aid the transformation of big data into knowledge discovery and drive significant innovations in a wide range of research fields.Given the rapid data production,biological databases continue to increase in size and importance.To build a catalog of worldwide biological databases,we curate a total of 5825 biological databases from 8931 publications,which are geographically distributed in 72 countries/regions and developed by 1975 institutions(as of September 20,2022).We further devise a z-index,a novel index to characterize the scientific impact of a database,and rank all these biological databases as well as their hosting institutions and countries in terms of citation and z-index.Consequently,we present a series of statistics and trends of worldwide biological databases,yielding a global perspective to better understand their status and impact for life and health sciences.An up-to-date catalog of worldwide biological databases,as well as their curated meta-information and derived statistics,is publicly available at Database Commons(http://gffzz77e3413bc06540edsfwn6knw6w05o6nuw.ffgz.tsg.suse.edu.cn/databasecommons/). | Lina Ma Dong Zou Lin Liu Huma Shireen Amir AAbbasi Alex Bateman Jingfa Xiao Wenming Zhao Yiming Bao Zhang Zhang | 2023 | Genomics, Proteomics & Bioinformatics2023，21，5： | 0 |
| 18 | 走出商品房显示文摘商品房从来不敢小觑广告的威力,就像当撰稿人听到要采访这栋房子时,脑海中马上泛起电视上一幕幕声音铿锵的介绍。毕竟'东莞常平紫荆花园'是近年数个大做宣传的楼盘之一,单单听到这几个字的组合,便可以马上联想到广告片明星、偌大的庭园和楼房景色,还有一项项吸引买家的条件。 | Necille Alex Ma 李慧欣 | 2000 | 城市住宅2000，0，9： | 0 |
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