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| 1 | Outcomes and patients' perspectives of transition from paediatric to adult care in inflammatory bowel disease显示文摘AIM: To describe the disease and psychosocialoutcomes of an inflammatory bowel disease(IBD) transition cohort and their perspectives.METHODS: Patients with IBD, aged > 18 years, who had moved from paediatric to adult care within 10 years were identified through IBD databases at three tertiary hospitals. Participants were surveyed regarding demographic and disease specific data and their perspectives on the transition process. Survey response data were compared to contemporaneously recorded information in paediatric service case notes. Data were compared to a similar age cohort who had never received paediatric IBD care and therefore who had not undergone a transition process. RESULTS: There were 81 returned surveys from 46 transition and 35 non-transition patients. No statistically significant differences were found in disease burden, disease outcomes or adult roles and responsibilities between cohorts. Despite a high prevalence of mood disturbance(35%), there was a very low usage(5%) of psychological services in both cohorts. In the transition cohort, knowledge of their transition plan was reported by only 25/46 patients and the majority(54%) felt they were not strongly prepared. A high rate(78%) of discussion about work/study plans was recorded prior to transition, but a near complete absence of discussion regarding sex(8%), and other adult issues was recorded. Both cohorts agreed that their preferred method of future transition practices(of the options offered) was a shared clinic appointment with all key stakeholders. CONCLUSION: Transition did not appear to adversely affect disease or psychosocial outcomes. Current transition care processes could be optimised, with better psychosocial preparation and agreed transition plans. | Alice L Bennett David Moore Peter A Bampton Robert V Bryant Jane M Andrews | 2016 | World Journal of Gastroenterology2016，22，8： | 3 |
| 2 | Critical factors for implementing IS014001 standard in Unit- ed States industrial companies 显示文摘 | Khalid A Babakri robert A Bennett Matthew Franchetti | 2003 | Journal of Cleaner Pro- duction2003，，7： | 1 |
| 3 | Indentifieation of the site of phosphorylation on the osmosensor显示文摘 | Roberts D Bennett D W Forst S A | 1994 | J Biol Chem1994，269，： | 1 |
| 4 | Microbial precipitation of dolomite in methanogenie groundwater显示文摘 | Roberts J A Bennett P C Gonzlez L A | 2004 | Geology2004，32，： | 1 |
| 5 | Differential effects of atrial and brain natriuretic peptides on human pulmonary artery:An in vitro study显示文摘BACKGROUND The prevalence of cardiovascular diseases,especially heart failure,continues to rise worldwide.In heart failure,increasing levels of circulating atrial natriuretic peptide(ANP)and brain natriuretic peptide(BNP)are associated with a worsening of heart failure and a poor prognosis.AIM To test whether a high concentration of BNP would inhibit relaxation to ANP.METHODS Pulmonary arteries were dissected from disease-free areas of lung resection,as well as pulmonary artery rings of internal diameter 2.5–3.5 mm and 2 mm long,were prepared.Pulmonary artery rings were mounted in a multiwire myograph,and a basal tension of 1.61gf was applied.After equilibration for 60 min,rings were pre-constricted with 11.21μmol/L PGF2α(EC80),and concentration response curves were constructed to vasodilators by cumulative addition to the myograph chambers.RESULTS Although both ANP and BNP were found to vasodilate the pulmonary vessels,ANP is more potent than BNP.pEC50 of ANP and BNP were 8.96±0.21 and 7.54±0.18,respectively,and the maximum efficacy(Emax)for ANP and BNP was-2.03 gf and-0.24 gf,respectively.After addition of BNP,the Emax of ANP reduced from-0.96gf to-0.675gf(P=0.28).CONCLUSION BNP could be acting as a partial agonist in small human pulmonary arteries,and inhibits relaxation to ANP.Elevated levels of circulating BNP could be responsible for the worsening of decompensated heart failure.This finding could also explain the disappointing results seen in clinical trials of ANP and BNP analogues for the treatment of heart failure. | Azar Hussain Robert T Bennett Zaheer Tahir Emmanuel Isaac Mubarak A Chaudhry Syed S Qadri Mahmoud Loubani Alyn H Morice | 2019 | World Journal of Cardiology2019，11，10： | 1 |
| 6 | SME growth: The rela- tionship with business advice and external collaboration显示文摘 | Paul J A Robson Robert J Bennett | | Small Business Economics0，2000，15： | 1 |
| 7 | Efficacy of a subsurface-flow wetland using the estuarine sedge Juncus kraussii to treat effluent from inland saline aquaculture显示文摘 | Lymbery A J Doupé Robert G Bennett T Starcevich MR | 2006 | Aquacultural Engineering2006，34，1： | 1 |
| 8 | The role of the pod in seed development: Strategies for manipulating yield 显示文摘 | Bennett E J Roberts J A Carol W | 2011 | New Physiologist2011，190，4： | 1 |
| 9 | Smaller Is Better显示文摘 | Bennett Robert A | 2002 | US BanKer2002，2002，： | 1 |
| 10 | Development,validation and comparison of multivariable risk scores for prediction of total stroke and stroke types in Chinese adults:a prospective study of 0.5 million adults显示文摘Background and purpose Low-income and middle-income countries have the greatest stroke burden,yet remain understudied.This study compared the utility of Framingham versus novel risk scores for prediction of total stroke and stroke types in Chinese adults.Methods China Kadoorie Biobank(CKB)is a prospective study of 512726 adults,aged 30-79 years,recruited from 10 areas in China in 2004-2008.By 1 January 2018,43234 incident first stroke cases(36310 ischaemic stroke(IS);8865 haemorrhagic stroke(HS))were recorded in 503842 participants with no history of stroke at baseline.We compared the predictive utility of the Framingham Stroke Risk Profile(FSRP)with novel CKB stroke risk scores and included recalibration,refitting,stratifying by study area and addition of other risk factors.Discrimination was assessed using area under the receiver operating characteristic curve(AUC)and calibration was assessed using Greenwood-Nam-D’Agostinoχ^(2) statistics.Results Incidence of total stroke varied fivefold by area in China.The FSRP had good discrimination for total stroke(AUC(95%CI);men:0.78(0.77 to 0.79),women:0.77(95%CI 0.76 to 0.78)),but poor calibration(χ^(2);men:1,825,women:3,053),substantially underestimating absolute risks.Recalibration reducedχ^(2) by>80%,but did not improve discrimination.Refitting the FSRP did not materially improve discrimination,but further improved calibration.Stratification by area improved discrimination(AUC;men:0.82(0.82 to 0.83);women:0.82(0.82 to 0.83)),but not calibration.Adding other risk factors yielded modest,but statistically significant,improvements in the AUCs.The findings for IS and HS were similar to those for total stroke.Conclusions The FSRP reliably differentiated Chinese adults with incident stroke,but substantially underestimated the absolute risks of stroke.Novel local risk prediction equations that took account of differences in stroke incidence within China enhanced risk prediction of total stroke and major stroke pathological types. | Matthew Chun Robert Clarke Tingting Zhu David Clifton Derrick A Bennett Yiping Chen Yu Guo Pei Pei Jun Lv Canqing Yu Ling Yang Liming Li Zhengming Chen Benjamin J Cairns 无 | 2022 | Stroke & Vascular Neurology2022，7，4： | 1 |
| 11 | Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline显示文摘 | Talbot Konrad Wang Hoau-Yan Kazi Hala Han Li-Ying Bakshi Kalindi P Stucky Andres Fuino Robert L Kawaguchi Krista R Samoyedny Andrew J Wilson Robert S Arvanitakis Zoe Schneider Julie A Wolf Bryan A Bennett David A Trojanowski John Q Arnold | 2012 | EN2012，，4： | 1 |
| 12 | Microbial precipitation of dolomite in methanogenic groundwater显示文摘 | Roberts J A Bennett P C Gonz lez L A | 2004 | Geology2004，32，： | 1 |
| 13 | Microbial precipitation of dolomite in methanogenic groundwater 显示文摘 | Roberts J A Bennett P C Gonzalez L A | 2004 | Geology2004，32，： | 1 |
| 14 | Microbial precipitation of dolomite in methanogenic groundwater显示文摘 | Roberts J Bennett P C Gonz(:tlez L A | 2004 | Geology2004，32，： | 1 |
| 15 | SME growth: The relationship with business advice and external collaboration显示文摘 | PAUL J A ROBSON ROBERT J BENNETT | 2000 | Small Business Economics2000，15，： | 1 |
| 16 | Change in quality of life after transcatheter aortic valve implantation and aortic valve replacement surgery in Australian patients aged ≥ 75 years: the effects of EuroSCORE and patient operability显示文摘ObjectiveTo 决定到差别,在在 transcatheter 之间的生活(QOL ) 的通用质量,大动脉的阀门培植(TAVI ) 和病人们由 EuroSCORE 和心队操作性 assessment.MethodsA 解释了的外科的大动脉的阀门代替(AVR ) 与 EuroSCORE > 146 个高风险的病人总计的程度;6 并且年老的 ≥75 年经历了 TAVI (n = 80 ) 或大动脉的阀门代替(n = 66 ) 在 2010 年 2 月和 2013 年 7 月之间。75 个病人的一个总数也完成了外科手术前并且六项月 SF-12 QOL 措施。分析检验了事件主要病态,比较了在调整的组之间的六月 QOL 因为 EuroSCORE 和操作性,和临床上重要的 QOL 改进和 deterioration.ResultsThe AVR 的确定的率组织要求的更长的通风(>24 h )(TAVI 5.0% 对 AVR 20.6% , P = 0.004 ) 并且红血房间的更多的单位[TAVI 0 (0-1 ) 对 AVR 2 (0-3 ) , P = 0.01 ] 。新肾的失败在 TAVI 是更高的(TAVI 5.0% 对 AVR 0% , P = 0.06 ) 。报导的 TAVI 病人显著地降低活力(P = 0.01 ) 由到 AVR 病人的比较,然而,这些调查结果在为操作性的调整以后不再是重要的。在里面两过程,临床上重要的 QOL 改进是普通的[范围25.0%(一般健康)-62.9%(物理角色)]而在 QOL 的恶化不太经常发生了[范围9.3%(物理角色)-33.3%(心理健康)]在 QOL 的 .ConclusionsClinically 重要的改进和恶化在在高风险的六个月是明显的老大动脉的阀门代替病人。一旦操作性被考虑,全面 QOL 没在 TAVI 和 AVR 之间不同。 | Phillip J. Tully Prakash Roshan Greg D Rice Ajay Sinhal Jayme S Bennetts Robert A Baker | 2015 | Journal of Geriatric Cardiology2015，12，1： | 0 |
| 17 | Characterization of optimal resting tension in human pulmonary arteries显示文摘AIM To determine the optimum resting tension(ORT) for in vitro human pulmonary artery(PA) ring preparations.METHODS Pulmonary arteries were dissected from disease free sections of the resected lung in the operating theatre and tissue samples were directly sent to the laboratory in Krebs-Henseleit solution(Krebs).The pulmonary arteries were then cut into 2 mm long rings.PA rings were mounted in 25 m L organ baths or 8 m L myograph chambers containing Krebs compound(37 ℃,bubbled with 21% O_2:5% CO_2) to measure changes in isometric tension.The resting tension was set at 1-gram force(gf) with vessels being left static to equilibrate for duration of one hour.Baseline contractile reactions to 40 mmol/L KCl were obtained from a resting tension of 1 gf.Contractile reactions to 40 mmol/L KCl were then obtained from stepwise increases in resting tension(1.2,1.4,1.6,1.8 and 2.0 gf).RESULTS Twenty PA rings of internal diameter between 2-4 mmwere prepared from 4 patients.In human PA rings incrementing the tension during rest stance by 0.6 gf,up to 1.6 gf significantly augmented the 40 mmol/L KCl stimulated tension.Further enhancement of active tension by 0.4 gf,up to 2.0 gf mitigate the 40 mmol/L KCl stimulated reaction.Both Myograph and the organ bath demonstrated identical conclusions,supporting that the radial optimal resting tension for human PA ring was 1.61 g.CONCLUSION The radial optimal resting tension in our experiment is 1.61 gf(15.78 m N) for human PA rings. | Azar Hussain Robert T Bennett Mubarak A Chaudhry Syed S Qadri Mike Cowen Alyn H Morice Mahmoud Loubani | 2016 | World Journal of Cardiology2016，8，9： | 0 |
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