|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | High performance liquid chromatographic separation of thirteen drugs collected in Chinese Pharmacopoeia 2010(Ch.P2010) on cellulose ramification chiral stationary phase显示文摘The enantiomers separation of thirteen drugs collected in Ch.P2010 was performed on chiral stationary phase of cellulose ramification (chiralpak OD and chiralpak OJ) by high performance liquid chromatographic (HPLC) methods, which included ibuprofen (C1), ketoprofen (C2), nitrendipine (C3), nimodipine (C4), felodipine (C5), omeprazole (C6), praziquantel (C7), propranolol hydrochloride (C8), atenolol (C9), sulpiride (C10), clenbuterol hydrochloride (C11), verapamil hydrochloride (C12), and chlorphenamine maleate (C13). The mobile phase consisted of isopropanol and n-hexane. The detection wavelength was set at 254 nm and the fiow rate was 0.7 mL/min. The enantiomers separation of these thirteen racemates on chiralpak OD column and chiralpak OJ column was studied, while the effects of proportion of organic additives, alcohol displacer and temperature on the separation were studied. And the mechanism of some of racemates was discussed. The results indicated that thirteen chiral drugs could be separated onchiral stationary phase of cellulose ramification in normal phase chromatographic system. The chromatographic retention and resolution of enantiomers could be adjusted by factors including column temperature and the concentration of alcohol displacer and organic alkaline modifier in mobile phase. It was shown that the resolution was improved with reducing concentration of alcohol displacer. When concentration of organic alkaline modifier was 0.2% (v/v), the resolution and the peak shape were fairly good. Most racemates mentioned above had better resolution at column temperature of 25 1C. When racemates were separated, the temperature should be kept so as to obtain stable separation results. | Ying Zhoua,b, Chao Maa, Yan Wanga, Qi-Ming Zhangb, Yi-Ying Zhanga, Jie Fua, Hong Gaoc, Li-Xun Zhaoc aState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China bNational Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China cInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China | 2012 | Journal of Pharmaceutical Analysis2012，2，1： | 4 |
| 2 | Similarity assessment for scientific workflow clustering and recommendation显示文摘This article proposes to identify and recommend scientific workflows for reuse and repurposing.Specifically, a scientific workflow is represented as a layer hierarchy that specifies the hierarchical relations between this workflow, its sub-workflows, and activities. Semantic similarity is calculated between layer hierarchies of workflows. A graph-skeleton based clustering technique is adopted for grouping layer hierarchies into clusters.Barycenters in each cluster are identified, which serve as core workflows in this cluster, for facilitating the cluster identification and workflow ranking and recommendation with respect to the requirement of scientists. | Zhangbing ZHOU Zehui CHENG Yueqin ZHU | 2016 | Science China(Information Sciences)2016，59，11： | 2 |
| 3 | Audio steganography with AES for real-time covert voice over internet protocol communications显示文摘As a popular real-time service on the Internet,Voice over Internet Protocol(VoIP)communication attracts more and more attention from the researchers in the information security field.In this study,we proposed a VoIP steganographic algorithm with variable embedding capacities,incorporating AES and key distribution,to realize a real-time covert VoIP communication.The covert communication system was implemented by embedding a secret message encrypted with symmetric cryptography AES-128 into audio signals encoded by PCM codec.At the beginning of each VoIP call,a symmetric session key(SK)was assigned to the receiver with a session initiation protocol-based authentication method.The secret message was encrypted and then embedded into audio packets with diferent embedding algorithms before sending them,so as to meet the realtime requirements of VoIP communications.For each audio packet,the embedding capacity was calculated according to the specific embedding algorithm used.The encryption and embedding processes were almost synchronized.The time cost of encryption was so short that it could be ignored.As a result of AES-based steganography,observers could not detect the hidden message using simple statistical analysis.At the receiving end,the corresponding algorithm along with the SK was employed to retrieve the original secret message from the audio signals.Performance evaluation with state-of-the-art network equipment and security tests conducted using the Mann-Whitney-Wilcoxon method indicated that the proposed steganographic algorithm is secure,efective,and robust. | TANG ShanYu JIANG YiJing ZHANG LiPing ZHOU ZhangBing | 2014 | Science China(Information Sciences)2014，57，3： | 2 |
| 4 | An Improved Double-Threshold Method Based on Gradient Histogram显示文摘This paper analyzes the characteristics of the output gradient histogram and shortages of several traditional automatic threshold methods in order to segment the gradient image better. Then an improved double\|threshold method is proposed, which is combined with the method of maximum classes variance, estimating\|area method and double\|threshold method. This method can automatically select two different thresholds to segment gradient images. The computer simulation is performed on the traditional methods and this algorithm and proves that this method can get satisfying result. | YANGShen CHENShu-zhen ZHANGBing | 2004 | Wuhan University Journal of Natural Sciences2004，9，4： | 2 |
| 5 | Effects of organic strength on performance of microbial electrolysis cell fed with hydrothermal liquefied wastewater显示文摘Microbial electrochemical technology has drawn increasing attention for the treatment of recalcitrant wastewater as well as production of energy or value-added chemicals recently.However,the study on the treatment of hydrothermal liquefied wastewater(HTL-WW)using microbial electrolysis cell(MEC)is still in its infancy.This study focused on the effects of organic loading rates(OLRs)on the treatment efficiency of recalcitrant HTL-WW and hydrogen production via the MEC.In general,the chemical oxygen demand(COD)removal rate was more than 71.74%at different initial OLRs.Specially,up to 83.84%of COD removal rate was achieved and the volatile fatty acids were almost degraded at the initial OLR of 2 g COD/L·d in the anode of MEC.The maximum hydrogen production rate was 3.92 mL/L·d in MEC cathode,corresponding to a hydrogen content of 7.10%at the initial OLR of 2 g COD/L·d.And in the anode,the maximum methane production rate of 826.87 mL/L·d was reached with its content of 54.75%at the initial OLR of 10 g COD/L·d.Analysis of electrochemical properties showed that the highest open circuit voltage of 0.48 V was obtained at the initial OLR of 10 g COD/L·d,and the maximum power density(1546.22 mW/m3)as well as the maximum coulombic efficiency(6.01%)were obtained at the initial OLR of 8 g COD/L·d.GC-MS analysis revealed the existence of phenols and heterocyclic matters in the HTL-WW,such as 1-acetoxynonadecane and 2,4-bis(1-phenylethyl)-phenol.These recalcitrant compounds in HTL-WW were efficiently removed via MEC,which was probably due to the combination effect of microbial community and electrochemistry in MEC anode. | Shen Ruixia Lu Jianwen Zhu Zhangbing Duan Na Lu Haifeng Yuanhui Zhang Liu Zhidan | 2017 | International Journal of Agricultural and Biological Engineering2017，10，3： | 2 |
| 6 | Generalized fuzzy groups and many-valued implica-tions 显示文摘 | Xuehai Yuana Cheng Zhangb Rena Yonghong | 2003 | Fuzzy Sets and Systems2003，138，： | 1 |
| 7 | Biocrude oil production from Chlorella sp.cultivated in anaerobic digestate after UF membrane treatment显示文摘Algae cultivation in animal wastewater could recover nutrient resources,and harvest considerable amount of algae biomass for biofuel conversion.In this study,Chlorella sp.cultivated in ultrafiltration(UF)membrane treated anaerobic digestion effluent of chicken manure was converted into biocrude oil through hydrothermal liquefaction(HTL).The potential of biocrude production from grown Chlorella sp.was studied through changing the operational conditions of HTL,i.e.,holding temperature(HT,250℃-330℃),retention time(RT,0.5-1.5 h),and total solid(TS)(15 wt%-25 wt%)of the feedstock.The highest biocrude oil yield was 32.9%at 330℃,1.5 h and 20 wt%TS.The single factor experiments of HT also suggested that the biocrude oil yield decreased when the temperature was higher than 330℃.There were no significant differences of elemental contents in biocrude samples.The maximum higher heating values(HHV)of Chlorella sp.biocrude was 40.04 MJ/kg at HT of 330℃,RT of 1 h and TS of 15 wt%.This study suggests the great potential for energy recovery from Chlorella sp.cultivated in UF membrane treated anaerobic digestion effluent via HTL. | Wang Meng Wang Xinfeng Zhu Zhangbing Lu Jianwen Yuanhui Zhang Li Baoming Lu Haifeng Duan Na Zhang Dongming Dong Taili Liu Zhidan | 2017 | International Journal of Agricultural and Biological Engineering2017，10，1： | 1 |
| 8 | 沿着中国青海省柴达木盆地冻土沼泽地区两阶段关闭热虹吸冷却效果现场测试研究[J]显示文摘 | ZhangB ShengY ChenJ LiJ | 2011 | 寒区科技2011，65，3： | 1 |
| 9 | miR-204-5pInhibitsprolifera-tionandinvasionandenhanceschemotherapeuticsensitivityofcolorectalcancercellsbydownregulatingRAB22A显示文摘 | YinY ZhangB WangW etal | 2014 | ClinCancerRes2014，20，23： | 1 |
| 10 | ApplicationofMonteCarloSimulationinantibioticPKandPD显示文摘 | ZHANGB ZHUZ | 2008 | 中国药学杂志2008，43，4： | 1 |
| 11 | Primary yolk sac tumor arisingin the pancreas with hepatic metastasis: a case report 显示文摘 | ZhangB Gao S Chen Y | 2010 | KoreanJ Radiol2010，11，4： | 1 |
| 12 | 显示文摘 | YANShou-xun ZHANGBing ZHAOYong-chao eta1(燕守勋 张兵 赵永超 等) | 2003 | 遥感技术与应用2003，18，4： | 1 |
| 13 | Fastdeterminationofthetetracyclinesinmilksamplesbytheaptamerbiosensor显示文摘 | ZhangJ ZhangB WuY etal | 2010 | Analyst2010，135，10： | 1 |
| 14 | Rapid and sensitive detec- tion of Little cherry virus 2 using isothermal reverse transcription-recombinase po|ymerase amplification 显示文摘 | Mekuriaa TA Zhangb S Eastwella KC | 2014 | J Virol Methods2014，205，： | 1 |
| 15 | Uptake and mass balance of trace metals for methane producing bacteria显示文摘 | Zhanga Y S Zhangb Z Y Suzuki K | 2003 | Biomass Bioenergy2003，25，： | 1 |
| 16 | Label-freeelectrochemicaldetectionoftetracyclinebyanaptamernano-biosensor显示文摘 | ZhangJ WuY ZhangB etal | 2012 | AnalyticalLetters2012，45，9： | 1 |
| 17 | SteamreformingofbioethanolfortheproductionofhydrogenoverceriasupportedCo,IrandNicatalysts显示文摘 | ZhangB TangX LiY etal | 2006 | CatalysisCommunications2006，7，6： | 1 |
| 18 | Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt-β-catenin signaling显示文摘 | ZhangB Li M McDonald T | 2013 | Blood2013，121，10： | 1 |
| 19 | Inhibition of connective tissue growth factor overexpression in diabetic retinopathy by SERPINA3K via blocking the WNT/beta-catenin pathway显示文摘 | ZhangB Zhou KK Ma JX | 2010 | Diabetes2010，59，： | 1 |
| 20 | Characterizationofthecrystalstructureoffungusfiber-anovelpotentialmaterial显示文摘 | HuangZH ZhangB ZhouL etal | 2012 | JournalofFunctionalMaterials2012，43，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员