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您的检索式：作者名="ZHOU Jiuning"
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| 1 | Relationships between daily total fluoride intake and dental fluorosis and dental caries显示文摘Objective:To explore the relationships between the daily total intake of fluoride,dental fluorosis and dental caries. Methods: An epidemiological method was used to investigate the daily total intake of fluoride,dental fluorosis,and dental caries among 236 and 290 children aged 8-13 years in a severe endemic area and in a non-fluorosis control area,respectively. The children were divided into eight subgroups according to each child’s estimated daily total intake of fluoride. The prevalence of dental fluorosis and dental caries in each group was calculated. Results: As expected,elevated levels of fluoride intake were significantly associated with a higher prevalence of dental fluorosis and an increasing amount of more severe defect dental fluorosis. When the daily total F intake was 2.78 mg/child/day,the prevalence of dental fluorosis was nearly 100%,with the prevalence of defect dental fluorosis increasing with increasing fluoride intake. There was also a significant negative(inverse) dose-response relationship between the daily total intake of fluoride and the overall preva-lence of dental caries,the prevalence of which decreased when the daily total intake of fluoride increased up to 3.32 mg/child/day. However,at higher levels of daily total intake of fluoride the prevalence of dental caries increased,giving rise to a U-shaped dose-response relationship curve. Conclusion: It is important to monitor total fluoride exposure and protect children from excessive fluoride intake,especially during the years of tooth development. | Quanyong Xiang Minghao Zhou Ming Wu Xinya Zhou Li Lin Jiuning Huan Youxing Liang | 2009 | Journal of Nanjing Medical University2009，23，1： | 3 |
| 2 | Mechanisms and influencing factors of the oil bank in fire flooding显示文摘Based on the systematic summary of current research on oil bank, the definition of oil bank in the process of fire flooding and its quantitative indices were proposed; and a new one-dimensional positive dry-fire flooding model considering temperature gradient was established based on the steady flow theory of gas and liquid phases. Single factor analysis and orthogonal experiments were adopted to verify the reliability and reveal the formation mechanisms and the controlling factors of the oil bank. Then the optimal conditions for the oil bank to form were discussed. The study results show the formation of the oil bank is controlled by 3 factors:(1) Oil bank would come into being within a certain temperature interval and above a critical value of temperature gradient(absolute value), with temperature too high or too low and temperature gradient absolute value lower than the critical value, the oil bank couldn't form.(2) For fire flooding process in heavy oil reservoirs, the viscosity of oil influences the width of oil bank and the speed at which oil bank forms; the lower the oil viscosity is, the wider the oil bank is and the faster the oil bank forms.(3) Oil saturation could affect the developing temperature and speed of oil bank. The favorable temperature at which oil bank develops gets lower and the accumulating speed of oil gets faster when the oil saturation is higher. By orthogonal experiments with the model, the optimal combinations of reservoir conditions for forming oil bank during fire flooding in heavy oil reservoirs can be worked out. | LI Qiu YI Leihao TANG Junshi GUAN Wenlong JIANG Youwei ZHENG Haoran ZHOU Jiuning WANG Xiaochun | 2018 | Petroleum Exploration and Development2018，45，3： | 0 |
| 3 | 阴茎癌改良临床病理肿瘤分期预后意义分析显示文摘背景与目的第8版美国癌症联合会-TNM(American Joint Committee on Cancer tumor–node–metastasis,AJCC-TNM)分期基于的是一些回顾性单中心研究。本研究旨在分析分期的预后价值,并探讨加入脉管癌栓的改良的临床病理肿瘤分期能否提高对T2–3期阴茎癌患者预后预测的准确性。方法根据第8版AJCC-TNM分期对2000年至2015年在中国和巴西2个中心接受治疗的411例患者所组成的训练队列进行分期。采用C-indexes一致性系数进行预测模型的评估,Bbootstrap再抽样法(1000次)进行模型验证。采用来自4个大洲15个中心接受治疗的436例患者的数据进行外部验证。结果根据第8版AJCC-TNM分期的T2和T3期患者有存活率重叠(P=0.587)。脉管癌栓是转移和生存的重要预后因素(均P <0.001)。多因素分析显示,仅脉管癌栓对癌症特异性生存(cancer-specific survival,CSS)有显著影响(风险比=1.587,95%置信区间=1.253–2.011;P=0.001)。发生脉管癌栓的T2和T3期患者的CSS显著短于无脉管癌栓的患者(P <0.001)。因此,我们提出一种改良的临床病理分期,将第8版AJCC-TNM分期的T2和T3期细分为如下2个新类别:T2期肿瘤侵犯尿道海绵体和/或阴茎海绵体和/或尿道且无淋巴管侵犯;T3期肿瘤侵犯尿道海绵体和/或阴茎海绵体和/或尿道并有淋巴管侵犯。加入脉管癌栓的改良的分期显示出预后分层改善,各组间CSS差异显著(均P <0.005),患者预后预测的准确性高于第8版AJCC-TNM分期(C-index,0.739 vs. 0.696)。以上结果在外部验证队列中得到了确认。结论 T2–3期阴茎癌是异质性的,加入脉管癌栓的改良临床病理分期比第8版AJCC-TNM分期对阴茎癌患者的预后预测能力更强。 | Zai-Shang Li Antonio Augusto Ornellas Christian Schwentner Xiang Li Alcides Chaux Georges Netto Arthur L.Burnett Yong Tang Jiun Hung Geng Kai Yao Xiao-Feng Chen Bin Wang Hong Liao Nan Liu Peng Chen Yong-Hong Lei Qi-Wu Mi Hui-Lan Rao Ying-Ming Xiao Qi-Lin Wang Zi-Ke Qin Zhuo-Wei Liu Yong-Hong Li Zi-Jun Zou Jun-Hang Luo Hui Li Hui Han Fang-Jian Zhou | 2019 | 癌症2019，38，6： | 0 |
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