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| 1 | Annual cost of illness of stomach and esophageal cancer patientsin urban and rural areas in China: A multi-center study显示文摘Objective: Stomach and esophageal cancer are imposing huge threats to the health of Chinese people whereas there were few studies on the financial burden of the two cancers.Methods: Costs per hospitalization of all patients with stomach or esophageal cancer discharged between September 2015 and August 2016 in seven cities/counties in China were collected, together with their demographic information and clinical details. Former patients in the same hospitals were sampled to collect information on annual direct non-medical cost, indirect costs and annual number of hospitalization. Annual direct medical cost was obtained by multiplying cost per hospitalization by annual number of hospitalization. Annual cost of illness(ACI)was obtained by adding the average value of annual direct medical cost, direct non-medical cost and indirect cost,stratified by sex, age, clinical stage, therapy and pathologic type in urban and rural areas. Costs per hospitalization were itemized into eight parts to calculate the proportion of each part. All costs were converted to 2016 US dollars(1 USD=6.6423 RMB).Results: Totally 19,986 cases were included, predominately male. Mean ages of stomach cancer and urban patients were lower than that of esophageal cancer and rural patients. ACI of stomach and esophageal cancer patients were $10,449 and $13,029 in urban areas, and $2,927 and $3,504 in rural areas, respectively. Greater ACI was associated with male, non-elderly patients as well as those who were in stage I and underwent surgeries.Western medicine fee took the largest proportion of cost per hospitalization.Conclusions: The ACI of stomach and esophageal cancer was tremendous and varied substantially among the population in China. Preferential policies of medical insurance should be designed to tackle with this burden and further reduce the health care inequalities. | Zhixun Yang Hongmei Zeng Ruyi Xia Qian Liu Kexin Sun Rongshou Zheng Siwei Zhang Changfa Xia He Li Shuzheng Liu Zhiyi Zhang Yuqin Liu Guizhou Guo Guohui Song Yigong Zhu Xianghong Wu Bingbing Song Xianzhen Liao Yanfang Chen Wenqiang Wei Guihua Zhuang Wanqing Chen | 2018 | Chinese Journal of Cancer Research2018，30，4： | 22 |
| 2 | Improved esophageal squamous cell carcinoma screening effectiveness by risk-stratified endoscopic screening:evidence from high-risk areas in China显示文摘Background:Risk-stratified endoscopic screening(RSES),which offers endoscopy to those with a high risk of esophageal cancer,has the potential to increase effectiveness and reduce endoscopic demands compared with the universal screening strategy(i.e.,endoscopic screening for all targets without risk prediction).Evidence of RSES in high-risk areas of China is limited.This study aimed to estimate whether RSES based on a 22-score esophageal squamous cell carcinoma(ESCC)risk prediction model could optimize the universal endoscopic screening strategy for ESCC screening in high-risk areas of China.Methods:Eight epidemiological variables in the ESCC risk prediction model were collected retrospectively from 26,618 individuals aged 40-69 from three high-risk areas of China who underwent endoscopic screening betweenMay 2015 and July 2017.The model’s performance was estimated using the area under the curve(AUC).Participants were categorized into a high-risk group and a low-risk group with a cutoff score having sensitivities of both ESCC and severe dysplasia and above(SDA)at more than 90.0%.Results:The ESCC risk prediction model had an AUC of 0.80(95% confidence interval:0.75-0.84)in this external population.We found that a score of 8(ranging from 0 to 22)had a sensitivity of 94.2% for ESCC and 92.5% for SDA.The RSES strategy using this threshold score would allow 50.6% of endoscopies to be avoided and save approximately US$0.59 million compared to universal endoscopic screening among 26,618 participants.In addition,a higher prevalence of SDA(1.7%vs.0.9%),a lower number need to screen(60 vs.111),and a lower average cost per detected SDA(US$3.22 thousand vs.US$5.45 thousand)could have been obtained by the RSES strategy.Conclusions:The RSES strategy based on individual risk has the potential to optimize the universal endoscopic screening strategy in ESCC high-risk areas of China. | He Li Chao Ding Hongmei Zeng Rongshou Zheng Maomao Cao Jiansong Ren Jufang Shi Dianqin Sun Siyi He Zhixun Yang Yiwen Yu Zhe Zhang Xibin Sun Guizhou Guo Guohui Song Wenqiang Wei Wanqing Chen Jie He | 2021 | Cancer Communications2021，41，8： | 3 |
| 3 | PMSM Vector Control Optimization Based on Fractional PI^(λ) of Rotational Speed Outer Loop of Dragonfly Algorithm显示文摘Aiming at the problems of slow dynamic response and weak robustness of integer-order proportional integral(PI)controller in double closed loop vector control system of permanent magnet synchronous motor(PMSM),a method of combining dragonfly algorithm with fractional order PI control is proposed for off-line parameter tuning for the outer loop of speed of the system.The parameter to be optimized is used as the spatial position of the optimal individual searching for food sources in the search space,and the error performance index integrated time and absolute error(ITAE)is used as its target fitness function.The motor speed regulation performances of traditional engineering experience setting integer order PI,particle swarm optimization algorithm tuning fractional order PI and dragonfly algorithm tuning fractional order PI are compared,respectively.Results show that the fractional order PI controller optimized by dragonfly algorithm can improve the dynamic response performance of the system,reduce overshoot and enhance robustness,which proves the feasibility and superiority of the optimization strategy. | ZENG Guohui FU Xiuwei LIU Jin HUANG Bo DU Tao ZHU Xiangchen | 2021 | Wuhan University Journal of Natural Sciences2021，26，5： | 3 |
| 4 | Single amino acid substitution of VP1 N17D or VP2 H145Y confers acid-resistant phenotype of type Asia1 foot-and-mouth disease virus显示文摘Infection by foot-and-mouth disease virus(FMDV) is triggered by the acidic pH in endosomes after virus uptake by receptor-mediated endocytosis. However, dissociation of the FMDV 146S particle in mildly acidic conditions renders inactivated foot-and-mouth disease(FMD) vaccines much less effective. Type Asia1 FMDV mutants with increased resistance to acid inactivation were selected to study the molecular basis of viral resistance to acid-induced disassembly and improve the acid stability of FMDV. Sequencing of capsid-coding regions revealed four amino acid replacements(VP1 N17D, VP2 H145Y, VP2 G192D, and VP3 K153E) in the viral population of the acid-selected 10th passage. We performed single or combined mutagenesis using a reverse genetic system, and our results provide direct experimental evidence that VP2 H145Y or VP1 N17D substitution confers an acid-resistant phenotype to type Asia1 FMDV. | Haiwei Wang Shanshan Song Jianxiong Zeng Guohui Zhou Decheng Yang Te Liang Li Yu | 2014 | Virologica Sinica2014，29，2： | 2 |
| 5 | Medical Additive Manufacturing: From a Frontier Technology to the Research and Development of Products显示文摘1.Research and development(R&D)and the challenges of raw materials for medical additive manufacturing Raw materials for medical additive manufacturing have a wide range of commonalities that are also seen in many other fields,making them an important basis in the field of three-dimensional(3D)printing.Problems and challenges related to material types,powder properties,formability,viscoelasticity,and so forth also share common features.For example,many metal materials are used in the field of aviation,while metals,polymers,and inorganic materials are used in the field of biomedicine.The most widely used materials in biomedicine are biocompatible.Various homogeneous and non-homogeneous composites are also available for 3D printing,and impose an additional challenge in additive manufacturing;the use of heterogeneous composites in 3D printing is particularly challenging. | Guixing Qiu Wenjiang Ding Wei Tian Ling Qin Yu Zhao Lianmeng Zhang Jian Lu Daijie Chen Guangyi Yuan Chengtie Wu Bingheng Lu Ruxu Du Jimin Chen Mo Elbestawi Zhongwei Gu Dichen Li Wei Sun Yuanjin Zhao Jie He Dadi Jin Bin Liu Kai Zhang Jianmo Li Kam WLeong Dewei Zhao Dingjun Hao Yingfang Ao Xuliang Deng Huilin Yang ShaoKeh Hsu Yingqi Chen Long Li Jianping Fan Guohui Nie Yun Chen Hui Zeng Wei Chen Yuxiao Lai | 2020 | Engineering2020，6，11： | 1 |
| 6 | Tuning the crystallite size of monoclinic ZrO_(2) to reveal critical roles of surface defects on m–ZrO_(2) catalyst for direct synthesis of isobutene from syngas显示文摘The effects of crystallite size on the physicochemical properties and surface defects of pure monoclinic ZrO_(2) catalysts for isobutene synthesis were studied.We prepared a series of monoclinic ZrO_(2) catalysts with different crystallite size by changing calcination temperature and evaluated their catalytic performance for isobutene synthesis from syngas.ZrO_(2) with small crystalline size showed higher CO conversion and isobutene selectivity,while samples with large crystalline size preferred to form dimethyl ether(DME)instead of hydrocarbons,much less to isobutene.Oxygen defects(ODefects)analyzed by X-ray photoelectron spectroscopy(XPS)provided evidence that more ODefectsoccupied on the surface of ZrO_(2) catalysts with smaller crystalline size.Electron paramagnetic resonance(EPR)and ultraviolet–visible diffuse reflectance(UV–vis DRS)confirmed the presence of high concentration of surface defects and Zr3+on mZrO_(2)-5.9 sample,respectively.In situ diffuse reflectance infrared Fourier transform spectroscopy(in situ DRIFTS)analysis indicated that the adsorption strength of formed formate species on catalyst reduced as the crystalline size decreased.These results suggested that surface defects were responsible for CO activation and further influenced the adsorption strength of surface species,and thus the products distribution changed.This study provides an in-depth insight for active sites regulation of ZrO_(2) catalyst in CO hydrogenation reaction. | Xuemei Wu Minghui Tan Bing Xu Shengying Zhao Qingxiang Ma Yingluo He Chunyang Zeng Guohui Yang Noritatsu Tsubaki Yisheng Tan | 2021 | Chinese Journal of Chemical Engineering2021，34，7： | 1 |
| 7 | Optimal Control Virtual Inertia of Optical Storage Microgrid Based on Improved Sailfish Algorithm显示文摘The optical storage microgrid system composed of power electronic converters is a small inertia system.Load switching and power supply intermittent will affect the stability of the direct current(DC)bus voltage.Aiming at this problem,a virtual inertia optimal control strategy applied to optical storage microgrid is proposed.Firstly,a small signal model of the system is established to theoretically analyze the influence of virtual inertia and damping coefficient on DC bus voltage and to obtain the constraint range of virtual inertia and damping coefficient;Secondly,aiming at the defect that the Sailfish optimization algorithm is easy to premature maturity,a Sailfish optimization algorithm based on the leak-proof net and the cross-mutation propagation mechanism is proposed;Finally,the virtual inertia and damping coefficient of the system are optimized by the improved Sailfish algorithm to obtain the best control parameters.The simulation results in Matlab/Simulink show that the virtual inertia control optimized by the improved Sailfish algorithm improves the system inertia as well as the dynamic response and robustness of the DC bus voltage. | LIAO Hongfei ZENG Guohui HUANG Bo MA Chi CHEN Gong ZHAO Jinbin | 2022 | Wuhan University Journal of Natural Sciences2022，27，3： | 1 |
| 8 | Cancer survival in C hina, 2003–2005: A population‐based study显示文摘 | Hongmei Zeng Rongshou Zheng Yuming Guo Siwei Zhang Xiaonong Zou Ning Wang Limei Zhang Jingao Tang Jianguo Chen Kuangrong Wei Suqin Huang Jian Wang Liang Yu Deli Zhao Guohui Song Jianshun Chen Yongzhou Shen Xiaoping Yang Xiaoping Gu Feng Jin Qilong Li Yanh | 2015 | Int. J. Cancer2015，，8： | 1 |
| 9 | Cancer survival in C hina, 2003–2005: A population‐based study显示文摘 | Hongmei Zeng Rongshou Zheng Yuming Guo Siwei Zhang Xiaonong Zou Ning Wang Limei Zhang Jingao Tang Jianguo Chen Kuangrong Wei Suqin Huang Jian Wang Liang Yu Deli Zhao Guohui Song Jianshun Chen Yongzhou Shen Xiaoping Yang Xiaoping Gu Feng Jin Qilong Li Yanh | 2015 | Cancer2015，，8： | 1 |
| 10 | Distribution and gas-bearing properties of Permian igneous rocks in Sichuan Basin, SW China显示文摘Based on the analysis of outcrop, seismic, logging and drilling data, combined with exploration practice, the characteristics,distribution, reservoir performance and gas-bearing properties of Permian igneous rocks in Sichuan Basin are studied. The study shows that central volcanic eruptive facies are developed in Sichuan Basin, and their lithological assemblages and distribution characteristics show obvious differences. The igneous rocks are mainly distributed in three regions: the southwestern part of the basin has dominantly largescale overflow facies basalts; the central and western part of the basin, Jianyang-Santai area, develop intrusive rocks, volcanic lavas(basalts)and pyroclastic rocks; and the eastern part of Sichuan, Dazhou-Liangping area, only develop diabase and basalts. Five aspects of understandings are achieved:(1) The Upper Permian igneous rocks can be divided into intrusive rocks and extrusive rocks, with the extrusive rocks as the main body. The chemical compositions of the extrusive rocks are characterized by both alkaline basalt and tholeiitic basalt, and belong to the subalkaline type of transitional basalt magma eruption.(2) There are obvious rhythmic structures vertically among overflow facies basalt, and the single rhythmic layer consists of, from bottom up, pyroclastic rocks(undeveloped), gray and dark gray porphyritic basalts(unstable), dark gray and purple microcrystalline-cryptocrystalline basalts, dark greyish green porous and amygdaloid basalts; the central volcanic eruption shows the rhythm and the vertical sequence of volcanic clastic rocks(agglomerates and breccias), volcanic lava, tuffaceous lava from bottom to top.(3) The pore types of basalt and pyroclastic rocks are diverse, mainly dissolution pore and de-vitrification micropore, but their physical properties are different. Basalt is characterized by ultra-low pore permeability, small reservoir thickness, and reservoirs are distributed in the upper and middle parts of the cycle, with poor lateral comparability. Volcanic clastic rocks are medium to high porous reservoirs(Well YT1: porosity: 8.66%?16.48%, average 13.76%) with large thickness and good reservoir quality.(4) Natural gas in basalts in southwestern basin mainly comes from Middle Permian, and natural gas in volcanic clastic rocks in central and western basin comes from Cambrian Qiongzhusi Formation.(5) Analysis of igneous reservoir-forming conditions in different areas shows that there are relatively insufficient gas sources and great differences in preservation conditions in southwestern basin.Reservoirs are poorly developed and gas-bearing is complex. The Jianyang-Santai area in the central and western part of Sichuan Basin has abundant hydrocarbon sources, developed reservoir, favorable preservation conditions and favorable gas geological conditions, and it is a favorable area for gas exploration. | MA Xinhua LI Guohui YING Danlin ZHAGN Benjian LI Ya DAI Xin FAN Yi ZENG Yunxian | 2019 | Petroleum Exploration and Development2019，46，2： | 1 |
| 11 | HOXC4 up-regulates NF-κB signaling and promotes the cell proliferation to drive development of human hematopoiesis, especially CD43+ cells显示文摘The hematopoietic function of HOXC4 has not been extensively investigated.Our research indicated that induction of HOXC4 in co-culture system from D10 significantly promoted productions of most hematopoietic progenitor cells.CD34−CD43+cells could be clearly classified into CD34−CD43^(low) and CD34−CD43^(high) sub-populations at D14.The former cells had greater myelogenic potential,and their production was not significantly influenced by induction of HOXC4.By contrast,the latter cells had greater potential to differentiate into megakaryocytes and erythroid cells,and thus had properties of erythroid–megakaryocyte common progenitors,which abundance was increased by∼2-fold when HOXC4 was induced from D10.For CD34−CD43^(low),CD34+CD43+,and CD34−CD43^(high) sub-populations,CD43 level served as a natural index for the tendency to undergo hematopoiesis.Induction of HOXC4 from D10 caused more CD43+cells sustain in S-phase with up-regulation of NF-κB signaling,which could be counteracted by inhibition of NF-κB signaling.These observations suggested that promotion of hematopoiesis by HOXC4 is closely related to NF-κB signaling and a change in cell-cycle status,which containing potential of clinical applications. | Jiahui Zeng Wencui Sun Jing Chang Danying Yia Lijiao Zhu Yonggang Zhang Xu Pan Ya Zhou Mowen Lai Guohui Bian Qiongxiu Zhou Jiaxin Liu Bo Chen FengMa | 2020 | Blood Science2020，2，4： | 1 |
| 12 | Application of Dynamic Voltage Restorer in Fault Ride-Through of Grid-Connected Photovoltaic Storage System显示文摘Problems in power quality such as temporary drops in grid voltage and flickers have been caught attention with the increasing capacity of the new energy grid-connected systems, such as photovoltaic(PV) and photovoltaic storage. To solve these problems, a dynamic voltage restorer(DVR) for fault ride-through of photovoltaic energy storage systems is presented. We select the appropriate DVR topology and compensation strategy for PV energy storage systems which are used as energy supply equipment for DVR. It proves to be energy-saving and solves the instability of photovoltaic output effectively. The intelligent algorithm that optimized the controller parameter of dynamic voltage restorer is used and the effectiveness of the controller strategy proposed has been assessed by time-domain simulations in the MATLAB/Simulink platform. | ZENG Guohui ZHANG Jie HUANG Bo | 2020 | Wuhan University Journal of Natural Sciences2020，25，4： | 0 |
| 13 | Suggestions of management on emergency responses to epidemic outbreaks in outpatient or emergency departments of tertiary teaching hospitals显示文摘Background Patients infected with the alpha,beta,and delta strains of coronavirus disease 2019(COVID-19)usually exhibit fever,dry cough,nasal congestion,sore throat,loss of taste or smell,runny nose,conjunctivitis,fatigue,myalgia,diarrhea,and other symptoms,[1]while patients infected with the omicron strain present mild symptoms,including nasal discharge,sore throat,sneezing,headache,and cough.[2]Some patients deliberately conceal the relevant medical history,which makes it difficult to find in the pre-examination screening in outpatient or emer-gency departments.Outpatient and emergency buildings are usually linked to each other,and some older floors are poorly ventilated.Once patients with COVID-19 see a doctor in an out-patient or emergency building,especially patients infected with the omicron strain,an outbreak of the epidemic in a large area is easily possible. | Ming Wu Zhiye Fang Li Zeng Xiaohua Xie Jun Liao Lei Yang Wenping Zheng Lijie Ren Biqiang Zhou Jianyi Xiong Yong Xu Guohui Nie | 2022 | Journal of Intensive Medicine2022，2，3： | 0 |
| 14 | AN EFFICIENT GPU ACCELERATION FORMAT FOR FINITE ELEMENT ANALYSIS显示文摘This paper proposes a new Graphics Processing Unit(GPU)-accelerated storage format to speed up Sparse Matrix Vector Products(SMVPs) for Finite Element Method(FEM) analysis of electromagnetic problems.A new format called Modified Compile Time Optimization(MCTO) format is used to reduce much execution time and design for hastening the iterative solution of FEM equations especially when rows have uneven lengths.The MCTO-applied FEM is about 10 times faster than conventional FEM on a CPU,and faster than other row-major ordering formats on a GPU.Numerical results show that the proposed GPU-accelerated storage format turns out to be an excellent accelerator. | Tian Jin Li Gong Fei Wu Zeng Guohui | 2013 | Journal of Electronics(China)2013，30，6： | 0 |
| 15 | A Short Text Classification Model for Electrical Equipment Defects Based on Contextual Features显示文摘The defective information of substation equipment is usually recorded in the form of text. Due to the irregular spoken expressions of equipment inspectors, the defect information lacks sufficient contextual information and becomes more ambiguous.To solve the problem of sparse data deficient of semantic features in classification process, a short text classification model for defects in electrical equipment that fuses contextual features is proposed. The model uses bi-directional long-short term memory in short text classification to obtain the contextual semantics of short text data. Also, the attention mechanism is introduced to assign weights to different information in the context. Meanwhile, this model optimizes the convolutional neural network parameters with the help of the genetic algorithm for extracting salient features. According to the experimental results, the model can effectively realize the classification of power equipment defect text. In addition, the model was tested on an automotive parts repair dataset provided by the project partners, thus enabling the effective application of the method in specific industrial scenarios. | LI Peipei ZENG Guohui HUANG Bo YIN Ling SHI Zhicai HE Chuanpeng LIU Wei CHEN Yu | 2022 | Wuhan University Journal of Natural Sciences2022，27，6： | 0 |
| 16 | Overexpression of HOXA9 upregulates NF-κB signaling to promote human hematopoiesis and alter the hematopoietic differentiation potentials显示文摘Background: The HOX genes are master regulators of embryogenesis that are also involved inhematopoiesis. HOXA9 belongs to a cluster of HOX genes that play extensively studied roles inhematopoiesis and leukemogenesis.Methods: We established HOXA9-inducible human embryonic stem cells (HOXA9/hESCs) with normalpluripotency and potential for hematopoiesis, which could be used to analyze gene function with highaccuracy. HOXA9/hESCs co-cultured with aorta–gonad–mesonephros-derived stromal cells (AGM-S3) wereinduced to overexpress HOXA9 with doxycycline (DOX) at various times after hematopoiesis started andthen subjected to flow cytometry.Results: Induction of HOXA9 from Day 4 (D4) or later notably promoted hematopoiesis and also increasedthe production of CD34+ cells and derived populations. The potential for myelogenesis was significantlyelevated while the potential for erythrogenesis was significantly reduced. At D14, a significant promotion ofS phase was observed in green fluorescent protein positive (GFP+) cells overexpressing HOXA9. NF-κBsignaling was also up-regulated at D14 following induction of HOXA9 on D4. All of these effects could becounteracted by addition of an NF-κB inhibitor or siRNA against NFKB1 along with DOX.Conclusions: Overexpression of HOXA9 starting at D4 or later during hematopoiesis significantly promotedhematopoiesis and the production of myeloid progenitors while reduced the production of erythroidprogenitors, indicating that HOXA9 plays a key role in hematopoiesis and differentiation of hematopoieticlineages. | Jiahui Zeng Danying Yi Wencui Sun Yuanlin Liu Jing Chang Lijiao Zhu Yonggang Zhang Xu Pan Yong Dong Ya Zhou Mowen Lai Guohui Bian Qiongxiu Zhou Jiaxin Liu Bo Chen Feng Ma | 2021 | Cell Regeneration2021，10，1： | 0 |
| 17 | Novel Rotors with Low Eddy Current Loss for High Speed Permanent Magnet Machines显示文摘Due to the large rotor eddy current loss and low thermal conductivity of carbon fiber sleeve,the high temperature usually occurs in high speed permanent magnet machines(HSPMMs)at the rated operation condition,resulting in irreversible demagnetization of the permanent magnet(PM).To obtain low rotor temperature,two novel rotor structures with low rotor eddy current loss are proposed in this paper.With the output torque and air gap flux density unchanged,the performance of HSPMMs with the two proposed rotor structures are analyzed based on finite element algorithm(FEA),including eddy current loss and temperature.Finally,the appropriate parameters of the proposed rotor structures are selected,and the electromagnetic(EM)performance,rotor stress and temperature are compared with those of the conventional rotor structure.Index Terms-Eddy current loss,finite element algorithm(FEA),electromagnetic(EM)performance,high speed permanent magnet machines(HSPMMs). | Xin Cheng Wei Xu Guanghui Du Guohui Zeng Jianguo Zhu | 2019 | CES Transactions on Electrical Machines and Systems2019，3，2： | 0 |
| 18 | RUNX1-205, a novel splice variant of the human RUNX1 gene, has blockage effect on mesoderm-hemogenesis transition and promotion effect during the late stage of hematopoiesis显示文摘Runt-related transcription factor 1(RUNX1)is required for definitive hematopoiesis;however,the functions of most human RUNX1 isoforms are unclear.In particular,the effects of RUNX1-205(a novel splice variant that lacks exon 6 in comparison with RUNX1b)on human hematopoiesis are not clear.In this study,a human embryonic stem cell(hESC)line with inducible RUNX1-205 overexpression was established.Analyses of these cells revealed that induction of RUNX1-205 overexpression at early stage did not influence the induction of mesoderm but blocked the emergence of CD34+cells,and the production of hematopoietic stem/progenitor cells was significantly reduced.In addition,the expression of hematopoiesis-related factors was downregulated.However,these effects were abolished when RUNX1-205 overexpression was induced after Day 6 in co-cultures of hESCs and AGM-S3 cells,indicating that the inhibitory effect occurred prior to generation of hemogenic endothelial cells,while the promotive effect could be observed during the late stage of hematopoiesis.This is very similar to that of RUNX1b.Interestingly,the mRNA expression profile of RUNX1-205 during hematopoiesis was distinct from that of RUNX1b,and the protein stability of RUNX1-205 was much higher than that of RUNX1b.Thus,the function of RUNX1-205 in normal and diseased models should be further explored. | Wencui Sun Jiahui Zeng Jing Chang Yuan Xue Yonggang Zhang Xu Pan Ya Zhou Mowen Lai Guohui Bian Qiongxiu Zhou Jiaxing Liu Bo Chen Feng Ma | 2020 | Journal of Molecular Cell Biology2020，12，5： | 0 |
| 19 | Sedimentary Changes of a Sand Layer in Liquefied Silts显示文摘A flume experiment was conducted to investigate the restratification of liquefied sediment strata under a wave load with the focus on the interbedded strata of coarse and fine sediments formed in estuarine and coastal areas.The aim of this research was to study the characteristics and processes of liquefied sediment strata in terms of wave-induced liquefaction.In the experiment,the bottom bed liquefied under the wave action and the liquefied soil moved in the same period with the overlying waves,and the track of the soil particles in the liquefied soil was an ellipse.The sand layer consisting of coarse particles in the upper part,settled into the lower silt layer.The sinking of coarse particles and upward migration of the fine particles of the lower layer induced by liquefied sediment fluctuations are the likely reasons for sedimentation of the sand layer in liquefied silt. | REN Yupeng ZENG Yu XU Xingbei XU Guohui | 2021 | Journal of Ocean University of China2021，20，5： | 0 |
| 20 | Knowledge Enhanced Pre-Training Model for Vision-Language-Navigation Task显示文摘Vision-Language-Navigation(VLN) task is a cross-modality task that combines natural language processing and computer vision. This task requires the agent to automatically move to the destination according to the natural language instruction and the observed surrounding visual information. To make the best decision, in every step during the navigation, the agent should pay more attention to understanding the objects, the object attributes, and the object relationships. But most current methods process all received textual and visual information equally. Therefore, this paper integrates more detailed semantic connections between visual and textual information through three pre-training tasks(object prediction, object attributes prediction, and object relationship prediction). The model will learn better fusion representation and alignment between these two types of information to improve the success rate(SR) and generalization. The experiments show that compared with the former baseline models, the SR on the unseen validation set(Val Unseen) increased by 7%, and the SR weighted by path length(SPL) increased by 7%;the SR on the test set(Test) increased 4%, SPL increased by 3%. | HUANG Jitao ZENG Guohui HUANG Bo GAO Yongbin LIU Jin SHI Zhicai | 2021 | Wuhan University Journal of Natural Sciences2021，26，2： | 0 |
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