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| 1 | A novel m6A reader Prrc2a controls oligodendroglial specification and myelination显示文摘While N6-methyladenosine (m6A), the most abundant internal modification in eukaryotic mRNA, is linked to cell differentiation and tissue development, the biological significance of m6A modification in mammalian glial development remains unknown. Here, we identify a novel m6A reader, Prrc2a (Proline rich coiled-coil 2A), which controls oligodendrocyte specification and myelination. Nestin-Cre-mediated knockout of Prrc2a induces significant hypomyelination, decreased lifespan, as well as locomotive and cognitive defects in a mouse model. Further analyses reveal that Prrc2a is involved in oligodendrocyte progenitor cells (OPCs) proliferation and oligodendrocyte fate determination. Accordingly, oligodendroglial-lineage specific deletion of Prrc2a causes a similar phenotype of Nestin-Cre-mediated deletion. Combining transcriptome-wide RNA-seq, m6A-RIP-seq and Prrc2a RIP-seq analysis, we find that Olig2 is a critical downstream target gene of Prrc2a in oligodendrocyte development. Furthermore, Prrc2a stabilizes Olig2 mRNA through binding to a consensus GGACU motif in the Olig2 CDS (coding sequence) in an m6A-dependent manner. Interestingly, we also find that the m6A demethylase, Fto, erases the m6A modification of Olig2 mRNA and promotes its degradation. Together, our results indicate that Prrc2a plays an important role in oligodendrocyte specification through functioning as a novel m6A reader. These findings suggest a new avenue for the development of therapeutic strategies for hypomyelination-related neurological diseases. | Rong Wu Ang Li Baofa Sun Jian-Guang Sun Jinhua Zhang Ting Zhang Yusheng Chen Yujie Xiao Yuhao Gao Qingyang Zhang Jun Ma Xin Yang Yajin Liao Wei-Yi Lai Xiaolong Qi Shukun Wang Yousheng Shu Hai-Lin Wang Fengchao Wang Yun-Gui Yang Zengqiang Yuan | 2019 | Cell Research2019，29，1： | 32 |
| 2 | Large-scale analysis of small RNAs derived from traditional Chinese herbs in human tissues显示文摘Plant-derived microRNAs have recently been reported to function in human blood and tissues. Controversy was immediately raised due to possible contamination and the lack of large sample sizes. Here, we report thousands of unique small RNAs derived from traditional Chinese medicine(TCM) herbs found in human blood cells and mouse lung tissues using a large-scale analysis.We extracted small RNAs from decoctions of 10 TCM plants(Ban Zhi Lian, Chai Hu, Chuan Xin Lian, Di Ding Zi Jin, Huang Qin, Jin Yin Hua, Lian Qiao, Pu Gong Ying, Xia Ku Cao, and Yu Xing Cao) and obtained millions of RNA sequences from each herb. We also obtained RNA-Seq data from the blood cells of humans who consumed herbal decoctions and from the lung tissues of mice administered RNAs from herbal decoctions via oral gavage. We identified thousands of unique small RNA sequences in human blood cells and mouse lung tissues. Some of these identified small RNAs from Chuan Xin Lian and Hong Jing Tian could be mapped to the genomes of the herbs, confirming their TCM plant origin. Small RNAs derived from herbs regulate mammalian gene expression in a sequence-specific manner, and thus are a superior novel class of herbal drug components that hold great potential as oral gene-targeted therapeutics, highlighting the important role of herbgenomics in their development. | Fengming Huang Jianchao Du Zhu Liang Zhichao Xu Jiantao Xu Yan Zhao Yexuan Lin Song Mei Quan He Jindong Zhu Qiang Liu Yanxu Zhang Yuhao Qin Wei Sun Jingyuan Song Shilin Chen Chengyu Jiang | 2019 | Science China(Life Sciences)2019，62，3： | 14 |
| 3 | Improved TQWT for marine moving target detection显示文摘Under the conditions of strong sea clutter and complex moving targets,it is extremely difficult to detect moving targets in the maritime surface.This paper proposes a new algorithm named improved tunable Q-factor wavelet transform(TQWT)for moving target detection.Firstly,this paper establishes a moving target model and sparsely compensates the Doppler migration of the moving target in the fractional Fourier transform(FRFT)domain.Then,TQWT is adopted to decompose the signal based on the discrimination between the sea clutter and the target’s oscillation characteristics,using the basis pursuit denoising(BPDN)algorithm to get the wavelet coefficients.Furthermore,an energy selection method based on the optimal distribution of sub-bands energy is proposed to sparse the coefficients and reconstruct the target.Finally,experiments on the Council for Scientific and Industrial Research(CSIR)dataset indicate the performance of the proposed method and provide the basis for subsequent target detection. | PAN Meiyan SUN Jun YANG Yuhao LI Dasheng XIE Sudao WANG Shengli CHEN Jianjun | 2020 | Journal of Systems Engineering and Electronics2020，31，3： | 6 |
| 4 | Catalytic Co9S8 decorated carbon nanoboxes as efficient cathode host for long-life lithium-sulfur batteries显示文摘Lithium sulfur(Li-S)batteries with high specific capacity and energy density can bring enormous opportunities for the nextgeneration energy storage systems.However,the severe dissolution and shuttle effect of lithium polysulfides(LiPSs)is still the key issue that seriously impedes the development of practical Li-S batteries.Here,polar Co9S8 inlaid carbon nanoboxes(Co9S8@C NBs)have been investigated as cathode host for high-performance Li-S batteries.In this integrated structure,Co9S8 nanocrystals not only provide strong chemisorptive capability for polar LiPSs,but also act as a catalyst to accelerate polysulfide redox reactions;while carbon nanobox with large inner space can offer enough space to relieve the volume expansion and physically confine LiPSs’dissolution.As a result,the S/Co9S8@C NBs cathode exhibits high specific capacity at 1C and the capacity retention was^83%after 400 cycles,corresponding to an average decay rate of only^0.043%per cycle. | Weiwei Sun Yujie Li Shuangke Liu Qingpeng Guo Yuhao Zhu Xiaobin Hong Chunman Zheng Kai Xie | 2020 | Nano Research2020，13，8： | 5 |
| 5 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection显示文摘Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined.Here,we exploited antibody cooperativity to develop a therapeutic antibody cocktail against SARS-CoV-2.On the basis of our previously identified humanized cross-neutralizing antibody H014,we systematically an a lyzed a fully human n aive antibody library and rationally identified a potent neutralizing antibody partner,P17,which confers effective protection in animal model.Cryo-EM studies dissected the nature of the P17 epitope,which is SARS-CoV-2 specific and distinctly different from that of HOI4.High-resolution structure of the SARS-CoV-2 spike in complex with HOM and P17,together with functional investigations revealed that in a two-antibody cocktail,synergistic neutralization was achieved by S1 shielding and conformational locking,thereby blocking receptor attachment and viral membrane fusion,conferring high potency as well as robustness against viral mutation escape.Furthermore,cluster analysis identified a hypothetical 3rd antibody partner for further reinforcing the cocktail as pan-SARS-CoVs therapeutics. | Hangping Yao Yao Sun Yong-Qiang Deng Nan Wang Yongcong Tan Na-Na Zhang Xiao-Feng Li Chao Kong Yan-Peng Xuc Qi Chen Tian-Shu Cao Hui Zhao Xintian Yan Lei Cao Zhe Lv Dandan Zhu Rui Feng Nanping Wu Wenhai Zhang Yuhao Hu Keda Chen Rong-Rong Zhang Qingyu Lv Shihui Sun Yunhua Zhou Run Yan Guan Yang Xinglu Chanjuan Liu Xiangyun Lu Linfang Cheng Hongying Qiu Xing-Yao Huang Tianhao Weng Danrong Shi Weidong Jiang Junbin Shao Lei Wang Jie Zhang Tao Jiang Guojun Lang Cheng-Feng Qinc Lanjuan Li Xiangxi Wang | 2021 | Cell Research2021，31，1： | 5 |
| 6 | Bistratal Au@Bi2S3 nanobones for excellent NIR-triggered/multimodal imaging-guided synergistic therapy for liver cancer显示文摘To fabricate a highly biocompatible nanoplatform enabling synergistic therapy and real-time imaging,novel Au@Bi2S3 core shell nanobones(NBs)(Au@Bi2S3 NBs)with Au nanorods as cores were synthesized.The combination of Au nanorods with Bi2S3 film made the Au@Bi2S3 NBs exhibit ultrahigh photothermal(PT)conversion efficiency,remarkable photoacoustic(PA)imaging and high computed tomography(CT)performance;these Au@Bi2S3 NBs thus are a promising nanotheranostic agent for PT/PA/CT imaging.Subsequently,poly(N-vinylpyrrolidone)-modified Au@Bi2S3 NBs(Au@Bi2S3-PVP NBs)were successfully loaded with the anticancer drug doxorubicin(DOX),and a satisfactory pH sensitive release profile was achieved,thus revealing the great potential of Au@Bi2S3-PVP NBs in chemotherapy as a drug carrier to deliver DOX into cancer cells.Both in vitro and in vivo investigations demonstrated that the Au@Bi2S3-PVP NBs possessed multiple desired features for cancer therapy,including extremely low toxicity,good biocompatibility,high drug loading ability,precise tumor targeting and effective accumulation.Highly efficient ablation of the human liver cancer cell HepG2 was achieved through Au@Bi2S3-PVP NB-mediated photothermal therapy(PTT).As both a contrast enhancement probe and therapeutic agent,Au@Bi2S3-PVP NBs provided outstanding NIR-triggered multi-modal PT/PA/CT imaging-guided PTT and effectively inhibited the growth of HepG2 liver cancer cells via synergistic chemo/PT therapy. | Ruizhuo Ouyang Penghui Cao Pengpeng Jia Hui Wang Tianyu Zong Chenyu Dai Jie Yuan Yuhao Li Dong Sun Ning Guo Yuqing Miao Shuang Zhou | 2021 | Bioactive Materials2021，6，2： | 5 |
| 7 | Fault tolerant multivehicle formation control framework with applications in multiquadrotor systems显示文摘Compared with the traditional monolithic systems,a group of vehicles operating cooperatively in a formation can achieve greater efficiency and capability [1,2].However,faults may occur more frequently in multivehicle formations because a large number of controllers,sensors,and com- munication equipment exist [3].Occasionally,a fault occurring in one vehicle of the formation may deteriorate the system performance or even cause catastrophic accidents.Thus,fault-tolerant formation control schemes are indispensable to achieve a reliable and safe operation. | Jiantao SHI Donghua ZHOU Yuhao YANG Jun SUN | 2018 | Science China(Information Sciences)2018，61，12： | 4 |
| 8 | Erythromycin loaded by tetrahedral framework nucleic acids are more antimicrobial sensitive against Escherichia coli(E.coli)显示文摘Erythromycin is a commonly used broad-spectrum antibiotic,but resistance to this antibiotic makes its use less effective.Considerable efforts,beside finding alternatives,are needed to enhance its antimicrobial effect and stability against bacteria.Tetrahedral framework nucleic acids(tFNAs),a novel delivery vehicle with a three-dimensional nanostructure,have been studied as a carrying platform of antineoplastic drugs.In this study,the use of tFNAs in delivering erythromycin into Escherichia coli(E.coli)was investigated for the first time.The tFNAs vehicle increased the bacterial uptake of erythromycin and promoted membrane destabilization.Moreover,it increased the permeability of the bacterial cell wall,and reduced drug resistance by improving the movement of the drug across the membrane.The tFNAs-based delivery system enhanced the effects of erythromycin against E.coli.It may therefore provide an effective delivery vehicle for erythromycin in targeting antibiotic-resistant bacteria with thick cell wall. | Yue Sun Yuhao Liu Bowen Zhang Shirong Shi Tao Zhang Dan Zhao Taoran Tian Qirong Li Yunfeng Lin | 2021 | Bioactive Materials2021，6，8： | 4 |
| 9 | Downregulation of ceramide synthase 1 promotes oral cancer through endoplasmic reticulum stress显示文摘C18 ceramide plays an important role in the occurrence and development of oral squamous cell carcinoma.However,the function of ceramide synthase 1,a key enzyme in C18 ceramide synthesis,in oral squamous cell carcinoma is still unclear.The aim of our study was to investigate the relationship between ceramide synthase 1 and oral cancer.In this study,we found that the expression of ceramide synthase 1 was downregulated in oral cancer tissues and cell lines.In a mouse oral squamous cell carcinoma model induced by 4-nitroquinolin-1-oxide,ceramide synthase 1 knockout was associated with the severity of oral malignant transformation.Immunohistochemical studies showed significant upregulation of PCNA,MMP2,MMP9,and BCL2 expression and downregulation of BAX expression in the pathological hyperplastic area.In addition,ceramide synthase 1 knockdown promoted cell proliferation,migration,and invasion in vitro.Overexpression of CERS1 obtained the opposite effect.Ceramide synthase 1 knockdown caused endoplasmic reticulum stress and induced the VEGFA upregulation.Activating transcription factor 4 is responsible for ceramide synthase 1 knockdown caused VEGFA transcriptional upregulation.In addition,mild endoplasmic reticulum stress caused by ceramide synthase 1 knockdown could induce cisplatin resistance.Taken together,our study suggests that ceramide synthase 1 is downregulated in oral cancer and promotes the aggressiveness of oral squamous cell carcinoma and chemotherapeutic drug resistance. | Wen Chen Chenzhou Wu Yafei Chen Yuhao Guo Ling Qiu Zhe Liu Haibin Sun Siyu Chen Zijian An Zhuoyuan Zhang Yi Li Longjiang Li | 2021 | International Journal of Oral Science2021，13，1： | 3 |
| 10 | The specific contribution of object's origin on artifacts categorization显示文摘Gelman and Bloom found that adults and children's object naming was sensitive to how an object was created (man-made or not), but they did not reveal on which specific level of conceptual system this effect was. Using a free-naming task and a force-choice task, two experiments were conducted to test a hypothesis that this effect was specifically on domain level ('artifact/non-artifact' distinction). In Experiment 1, participants were asked to name shortly-depicted objects, rate their confidence, and report their reasons for each naming response. Results showed that most of the naming responses in 'man-made' condition were in artifact domain, and most in 'natural' condition were in non-artifact domain, although in both conditions names were very divergent on basic level. In Experiment 2, another group of participants were asked to choose one from two names (one in artifact domain and the other in non-artifact domain) to match the same shortly-depicted objects presented in the first experiment. Re-sults of Experiment 1 on domain level were replicated in Experiment 2. These convergent findings supported the hypothesis that the effect of object's origin is specifically on domain level of conceptual system of objects. Reasons explicitly reported for naming responses in Experiment 1 suggested that participants might automatically infer objects' functions in 'man-made' condition but not in 'natural' condition. Here the function-based hypothesis of artifacts classification is discussed. | SUN Yuhao WANG Zhe FU Xiaolan | 2006 | Chinese Science Bulletin2006，51，23： | 3 |
| 11 | Pushing the limits of microwave absorption capability of carbon fiber in fabric design based on genetic algorithm显示文摘The field of electromagnetic wave absorption(EWA)requires the adaptability,tenability,and multifunction of high-performance materials in the future.The design and preparation of EWA materials aiming at performance requirements is the latest research hotspot.Here,a performancedriven strategy for simultaneously coordinating different target performances was proposed to optimize the structure of the periodical long continuous carbon/glass fiber fabric(PCGF)materials through algorithm and simulation.The optimized structure of the PCGF not only improves the impedance matching,but also introduces the induced orientation effect for a high cooperative loss of conductivity,resonance,and periodic structure.The flexible PCGF shows a broad effective absorption bandwidth(EAB)of 32.7 GHz covering a part of the C-band and the whole X-,Ku-,K-,and Ka-bands with a thickness(d)of only 0.92 mm and a density of 5.6×10^(−4) kg·cm^(−3).This highly designable fabric is promising for the EWA practical application owing to integrating the characteristics of good flexibility,acid and alkali resistance,bending resistance,excellent mechanical properties,and easy large-scale preparation. | Yuhao LIU Xiaoxiao HUANG Xu YAN Long XIA Tao ZHANG Jiahao SUN Yanan LIU Yu ZHOU | 2023 | Journal of Advanced Ceramics2023，12，2： | 3 |
| 12 | A comprehensive analysis of the Bencao(herbal)small RNA Atlas reveals novel RNA therapeutics for treating human diseases显示文摘Cross-kingdom herbal mi RNA was first reported in 2012.Using a modified herbal extraction protocol,we obtained 73,677,287sequences by RNA-seq from 245 traditional Chinese Medicine(TCM),of which 20,758,257 were unique sequences.We constructed a Bencao(herbal)small RNA(s RNA)Atlas(http://gffzz4a3adbfa122d4a47hcp900pwop5qu60nk.ffgz.tsg.suse.edu.cn),annotated the sequences by sequence-based clustering,and created a nomenclature system for Bencao s RNAs.The profiles of 21,757 mi RNAs in the Atlas were highly consistent with those of plant mi RNAs in mi RBase.Using software tools,our results demonstrated that all human genes might be regulated by s RNAs from the Bencao s RNA Atlas,part of the predicted human target genes were experimentally validated,suggesting that Bencao s RNAs might be one of the main bioactive components of herbal medicines.We established roadmaps for oligonucleotide drugs development and optimization of TCM prescriptions.Moreover,the decoctosome,a lipo-nano particle consisting of 0.5%–2.5%of the decoction,demonstrated potent medical effects.We propose a Bencao(herbal)Index,including small-molecule compounds(SM),protein peptides(P),nucleic acid(N),non-nucleic and non-proteinogenic large-molecule compounds(LM)and elements from Mendeleev's periodic table(E),to quantitatively measure the medical effects of botanic medicine.The Bencao s RNA Atlas is a resource for developing gene-targeting oligonucleotide drugs and optimizing botanical medicine,and may provide potential remedies for the theory and practice of one medicine. | Yinghao Cao Yexuan Lin Na Sun Xinyi Du Yixin Dong Song Mei Xingyu Deng Xiaobei Li Shaoting Guo Kegong Tang Jiaqi Liu Xiangyu Qiao Dandan Zhao Yuhao Qin Cong Zhang Tianyi Xin Xiaohu Shi Congzhao Zhou Tao Dong De-an Guo Benedikt MKessler Dong Xu Jingyuan Song Fengming Huang Xiaoyue Wang Chengyu Jiang | 2023 | Science China(Life Sciences)2023，66，10： | 2 |
| 13 | A 15-year analysis of molecular epidemiology of avian infectious bronchitis coronavirus in China显示文摘 | Zongxi Han Chuyang Sun Baolong Yan Xiaonan Zhang Yu Wang Chengren Li Qingxia Zhang Yazhen Ma Yuhao Shao Qiaoran Liu Xiangang Kong Shengwang Liu | 2010 | Infection Genetics and Evolution2010，，1： | 2 |
| 14 | A 15-year analysis of molecular epidemiology of avian infectious bronchitis coronavirus in China显示文摘 | Zongxi Han Chuyang Sun Baolong Yan Xiaonan Zhang Yu Wang Chengren Li Qingxia Zhang Yazhen Ma Yuhao Shao Qiaoran Liu Xiangang Kong Shengwang Liu | 2010 | Infection Genetics and Evolution2010，，1： | 2 |
| 15 | DEAP1 encodes a fasciclin-like arabinogalactan protein required for male fertility in rice显示文摘Arabinogalactan proteins(AGPs)are widely distributed in plant cells.Fasciclin-like AGPs(FLAs)belong to a subclass of AGPs that play important roles in plant growth and development.However,little is known about the biological functions of rice FLA.Herein,we report the identification of a male-sterile mutant of DEFECTIVE EXINE AND APERTURE PATTERNING1(DEAP1)in rice.The deap1 mutant anthers produced aberrant pollen grains with defective exine formation and a flattened aperture annulus and exhibited slightly delayed tapetum degradation.DEAP1 encodes a plasma membrane-associated member of groupⅢplant FLAs and is specifically and temporally expressed in reproductive cells and the tapetum layer during male development.Gene expression studies revealed reduced transcript accumulation of genes related to exine formation,aperture patterning,and tapetum development in deap1 mutants.Moreover,DEAP1 may interact with two rice D6 PROTEIN KINASE-LIKE3 s(OsD6PKL3s),homologs of a known Arabidopsis aperture protein,to affect rice pollen aperture development.Our findings suggested that DEAP1 is involved in male reproductive development and may affect exine formation and aperture patterning,thereby providing new insights into the molecular functions of plant FLAs in male fertility. | Dan Zhou Ting Zou Kaixuan Zhang Pingping Xiong Fuxing Zhou Hao Chen Gongwen Li Kaiyou Zheng Yuhao Han Kun Peng Xu Zhang Shangyu Yang Qiming Deng Shiquan Wang Jun Zhu Yueyang Liang Changhui Sun Xiumei Yu Huainian Liu Lingxia Wang Ping Li Shuangcheng Li | 2022 | Journal of Integrative Plant Biology2022，64，7： | 2 |
| 16 | Neuroprotection and Sensorimotor Functional Improvement by Curcumin after Intracerebral Hemorrhage in Mice显示文摘 | Yuhao Sun Minchao Dai Yongting Wang | 2011 | Neurotrau ma2011，28，12： | 1 |
| 17 | Integrated network pharmacology and proteomics to reveal the cognitive improvement effect of Wuzang Wenyang Huayu decoction on vascular dementia显示文摘To the Editor:Vascular dementia(VD)is a clinical disease characterized_by cognitive dysfunction and intellectual decline caused byvarious cerebrovascularfactors.The high incidence of VD in middle-aged and elderly people has become a major medical and social problem worldwide.li Since its specific pathogenesis has not been fully elucidated,clinical practice is stillfocused on improving cognition and sAylmteprntoamtivaetilcy,t rweiathtm heignht,seuffcehc taivse pnierascse atanmd faenwd sdidoen eepffeezcitl.s2,i traditional Chinese medicine has drawn medical attention and become a hotspot in the medical research field. | Yuhao Sun Xiaoyu Wen Zhuoxian Li Lijing Xu Meng Xia | 2022 | Chinese Medical Journal2022，135，19： | 1 |
| 18 | Naturally-formed objects categorized as artifacts:Effect of objects' functional depictions显示文摘Past research has identified a variety of factors that influence cognitive processing of artifact concepts, but few experiments tested possible interactive patterns among these factors. Using a natural language depiction based free naming task, we explored how an object's function and its history (information about how an object was formed by natural force) interact to affect categorization judgment in a 2×2 betweensubjects experiment (N = 169). The study had two key findings: (i) Without presenting an object's function, presenting the history of its natural formation increased subjects' tendency to name the object under the 'natural' domain and decreased their tendency to name it under the 'artifact' domain; (ii) once we presented the depiction of an object's function, the effect of history presentation on categorization disappeared:Subjects in both conditions strongly preferred naming objects as artifacts. In summary, presenting depiction of an object's function inhibited the effect of history on object categorization. Current findings suggest that an object's function plays a fundamental role in the cognitive processing of artifact concepts. | SUN YuHao WANG Zhe LIU Ye FU XiaoLan | 2010 | Chinese Science Bulletin2010，55，4： | 1 |
| 19 | Microbial community coexisting with harmful alga Karenia mikimotoi and microbial control of algal bloom in laboratory显示文摘Algicidal bacteria have been frequently isolated from algal blooming areas.However,knowledge regarding the microbial communities coexisting with microalgae and their potential application in preventing harmful algal blooms(HABs)is limited.In this study,we investigated the composition of the microbial community coexisting with harmful alga Karenia mikimotoi and its responses to algal control via nutrient stimulation or by adding algicidal strain in microcosms.The microorganisms inhabiting the K.mikimotoi culture consisted of 24 identifi ed phyla,including dominant Proteobacteria(relative abundance 76.24%±7.28%)and Bacteroidetes(22.67%±8.32%).Rhodobacteraceae,Phaeodactylibacter,and Maritimibacter predominated during the algal cultivation.Both the added nutrient and fermentation broth of algicidal strain Pseudoalteromonas QF1 caused a massive death of K.mikimotoi and substantial changes in the coexisting microbial community,in which Rhodobacteraceae and Phaeodactylibacter signifi cantly decreased,while Halomonas and Alteromonas increased.Core operational taxonomic units(OTUs)analysis indicated that 13 OTUs belonging to Rhodobacteraceae,Maritimibacter,Marivita,Nisaea,Phaeodactylibacter,Citreicella,Halomonas,Alteromonas,Marinobacter,Muricauda,and Pseudoalteromonas dominated the changes of the microbial communities observed in the K.mikimotoi culture with or without treatments.Collectively,this study indicated that microbial community inhabiting K.mikimotoi culture includes potential algicidal bacteria,and improves our knowledge about microbial community succession during biocontrol of K.mikimotoi via nutrient stimulation or by adding isolated algicidal strains. | Li SUN Peike GAO Yu LI Chao WANG Ning DING Junfeng CHEN Yuhao SONG Chunchen LIU Lun SONG Renjun WANG | 2022 | Journal of Oceanology and Limnology2022，40，3： | 1 |
| 20 | Phylogenetic analysis of infectious bronchitis coronaviruses newly isolated in China, and pathogenicity and evaluation of protection induced by Massachusetts serotype H120 vaccine against QX-like strains显示文摘 | Chuyang Sun Zongxi Han Huijie Ma Qinxia Zhang Baolong Yan Yuhao Shao Jia Xu Xiangang Kong Shengwang Liu | 2011 | Avian Pathology2011，，1： | 1 |
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