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| 1 | Vitamin D and autoimmune thyroid diseases显示文摘The role of vitamin D as an immune modulator has been emphasized in recent years,and low levels of the hormone were observed in several autoimmune diseases including multiple sclerosis and systemic lupus erythematosus.Vitamin D mediates its effect though binding to vitamin D receptor(VDR),and activation of VDR-responsive genes.While VDR gene polymorphism was found to associate with autoimmune thyroid diseases(AITDs),few studies examined levels of vitamin D in these patients and those that did yielded conflicting results.We therefore undertook to evaluate the levels of vitamin D in patients with AITDs compared to patients with non-AITDs and healthy controls.Serum vitamin D(25-OH)levels were measured in 50 patients with AITDs,42 patients with non-AITDs and 98 healthy subjects,utilizing the LIAISON chemiluminescence immunoassay(DiaSorin,Saluggia,Italy).VitaminD deficiency was designated at levels lower than 10 ng/ml.Antithyroid antibodies,thyroid functions and demographic parameters were evaluated in all patients.The prevalence of vitamin D deficiency was significantly higher in patients with AITDs compared with healthy individuals(72% versus 30.6%;P<0.001),as well as in patients with Hashimoto’s thyroiditis compared to patients with non-AITDs(79% versus 52%;P<0.05).Vitamin D deficiency also correlated to the presence of antithyroid antibodies(P=0.01)and abnormal thyroid function tests(P=0.059).Significantly low levels of vitamin D were documented in patients with AITDs that were related to the presence of anti thyroid antibodies and abnormal thyroid function tests,suggesting the involvement of vitamin D in the pathogenesis of AITDs and the advisability of supplementation. | Shaye Kivity Nancy Agmon-Levin Michael Zisappl Yinon Shapira Endre V Nagy Katalin Danko Zoltan Szekanecz Pnina Langevitz Yehuda Shoenfeld | 2011 | Cellular & Molecular Immunology2011，8，3： | 47 |
| 2 | Phosphorylation Meets Ubiquitination: The Control of NF-&kgr;B Activity显示文摘 | Michael Karin Yinon Ben-Neriah | 2000 | Annual Review of Immunology2000，，： | 2 |
| 3 | Helicobacter pylori serology in autoimmune diseases – fact or fiction?显示文摘 | Maya Ram Ori Barzilai Yinon Shapira Juan-Manuel Anaya Angela Tincani Ljudmila Stojanovich Stefano Bombardieri Nicola Bizzaro Shaye Kivity Nancy Agmon Levin Yehuda Shoenfeld | 2013 | Clinical Chemistry and Laboratory Medicine2013，，5： | 2 |
| 4 | Cytomegalovirus infection inpregnancy显示文摘 | Yinon Y Farine D Yudin MH | 2010 | J Obstet Gynaecol Can2010，32，4： | 1 |
| 5 | Social self-discrepancies from own and other standpoints and collective self-esteem 显示文摘 | Bizman A Yinon Y | 2004 | The Journal of Social Psychology2004，144，2： | 1 |
| 6 | Cytomegalovirus im fection Inpreg nancy显示文摘 | L Yinon Y Farine D Yudin MH | 2010 | J Obstet Gynaecol Can2010，32，4： | 1 |
| 7 | Delta and kappa opi- oid receptors in eyestalk ganglia of a crustacean显示文摘 | Hanke J Willig A Yinon U et O1 | 1997 | Brain Res1997，744，： | 1 |
| 8 | Myopia in the eye of developing chicks follow ing monocular and binocular lid closure显示文摘 | Yinon U Rose L Shapiro A | 1980 | Vision Res1980，20，2： | 1 |
| 9 | Circulating angiogenic factors in monochorionic twin pregnancies complicated by twin to twin transfusion syndrome and selective intra-uterine growth restriction显示文摘 | Yinon Y Ben Meir E Berezowsky A | | 0，，13： | 1 |
| 10 | Preterm premature rupture of membranes in the presence of cerelage : is the risk for intrauterine infection and adverse neonatal out- come increased 显示文摘 | Dlaskin M Yinon Y Whittle W L | 2012 | J Matem Fetal Neonatal Med2012，25，4： | 1 |
| 11 | Screening,diagnosis,and manage-ment of cytomegalovirus infection in pregnancy显示文摘 | Yinon Y Farine D Yudin MH | 2010 | Obstet GynecolSurv2010，65，11： | 1 |
| 12 | Fetal cardiac tumors:a sin- gle-centre experience of 40 cases 显示文摘 | Yinon Y Chitayat D Blaser S | 2010 | Prenat Diagn2010，8，30： | 1 |
| 13 | Preterm premature rupture of mem-branes in the presence of cerclage : is the risk for intra-uterine infectionand adverse neonatal outcome increased 显示文摘 | Laskin DM Yinon Y Whittle WL | 2012 | J Matem Fatal NeonatalMed2012，25，4： | 1 |
| 14 | Clinical outcome of cystectomy compared with unilateral salpingo-oophorectomy as fertilitysparing treatment of borderline ovarian tumors 显示文摘 | Yinon Y Beiner ME Gotlieb WH | 2007 | Fertil Steril2007，88，2： | 1 |
| 15 | Cy- tomegalovirus infection in pregnancy 显示文摘 | Yinon Y Farine D Yudin MH | 2010 | J Object Gynaecol Can2010，32，4： | 1 |
| 16 | Diffusion MRI findings in monochorionic twin pregnancies after intrauterine fetal death 显示文摘 | Hoffmann C Weisz B Yinon Y | 2013 | AJNR Am J Neuroradiol2013，34，1： | 1 |
| 17 | Useof low molecular weight heparin in pregnant womenwith mechanical heart valves显示文摘 | YINON Y SIU S C WARSHAFSKY C | 2009 | Am J Cardiol2009，104，： | 1 |
| 18 | Severe intrauterine growth restriction pregnancies have increased placental endoglin levels;hypoxie regulation via transforming growth factor-beta 3显示文摘 | Yinon Y Nevo O Xu J | 2008 | Am J Pathol2008，172，： | 1 |
| 19 | Fetal thymus size as a predictor of chorioamnionitis in women with preterm premature rupture of membranes显示文摘 | Yinon Y Zalel Y Weisz B | 2007 | Ultrasound Obstet Gynecol2007，9，6： | 1 |
| 20 | Cytomegalovirus infec- tion in pregnaney显示文摘 | Yinon Y Farine D Yudin M H | 2010 | J Obstet Gynaecol Can2010，32，4： | 1 |
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