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| 1 | Validation of glaucoma-like features in the rat episcleral vein cauterization model显示文摘 | Bai Yujing Zhu Yingting Chen Qin Xu Jing Marinko V. Sarunic Uri H. Saragovi Zhuo Yehong | 2014 | Chinese Medical Journal2014,,2: | 7 |
| 2 | Low serum albumin levels predict poor outcome in patients with acute ischaemic stroke or transient ischaemic attack显示文摘Background To examine the relationship of serum albumin with poor functional outcome and mortality in patients with acute ischaemic stroke(AIS)or transient ischaemic attack(TIA),and perform a meta-analysis to summarise the association.Methods We analysed data from the Third China National Stroke Registry(CNSR-Ⅲ).Patients were divided into four groups based on serum albumin levels at admission.The outcomes included poor functional outcome(modified Rankin Scale(mRS)score of 3 to 6)and mortality at 3 months and 1 year.Multiple logistic regression models and Cox regression models were used to evaluate the association,respectively.We used a fixed-effect model to calculate the risk ratio for poor functional outcome and a random-effect model for mortality in the meta-analysis.Results A total of 13618 patients were enrolled.During the 3-month follow-up period,compared with 40 to 44.9 g/L group,patients in<35 g/L group had an increased risk of poor functional outcome and mortality(adjusted OR 1.37(95%CI 1.12 to 1.67);adjusted HR 2.13(95%CI 1.41 to 3.23)).The relationship in per 10 g/L decreased serum albumin with prognosis was consistently inversed(adjusted OR 1.17(95%CI 1.01 to 1.35);adjusted HR 1.86(95%CI 1.30 to 2.64)).Also,low serum albumin levels were independently correlated with clinical outcomes at 1 year.In the meta-analysis,the OR for poor functional outcome pooled 3 studies per 1 g/L decrease was 1.03(95%CI 1.02 to 1.05),and the HR for mortality pooled 5 studies was 1.07(95%CI 1.03 to 1.11).Conclusions Low serum albumin levels predict poor functional outcome and mortality in patients with AIS or TIA. | Hongyu Zhou Anxin Wang Xia Meng Jinxi Lin Yong Jiang Jing Jing Yingting Zuo Yilong Wang Xingquan Zhao Hao Li Yongjun Wang | 2021 | Stroke & Vascular Neurology2021,6,3: | 7 |
| 3 | Fabrication of cotton nano-powder and its textile application显示文摘A combination of chemical and mechanical treatment of cotton produced cotton powder (fibrils) with a mean diameter of 97nm is analyzed by Laser Particle Size Analyzer. Transmission Electron Microscope (TEM) study showed that the diameter of the fibrils was about 10―30 nm and the length was from 70nm to over 400 nm. The powder was then coated onto fabrics (100% polyester fabric, 100% wool fabric and 100% cotton fabric). Scanning Electron Microscope (SEM) study showed that cotton fibrils were adhered to the surface of treated fabrics (fibers). The ultraviolet protection factor (UPF) value (AS/NZS 4399: 1996) for cotton fabrics increased about 20% after the treatment. This implies that the treated samples give a better protection from UV light. The moisture management test (MMT) of the fabrics such as wetting time at bottom, top maximum absorption rate, bottom maximum absorption rate, bottom maximum wetted radius and bottom spreading speed, et al., showed that there were significant changes after the treatment. These changes gave better moisture management ability to the treated fabrics and thus made the fabric more comfortable. However, Wide-angle X-ray Diffraction and Fourie Transform Infrared Spectroscopy analysis proved that supermolecular structure and chemical structure of treated fabrics were the same as the original fabrics. Other properties of the treated fabric such as thermal conductivity, wrinkle recovery, hand, et al., did not change. This implied that the basic function of the treated fabrics for the clothing industry was the same as untreated fabrics. This study is a foundation for further researches on textile application. | GUAN YingTing LI Yi | 2008 | Chinese Science Bulletin2008,53,23: | 6 |
| 4 | Globally optimal distributed Kalman filtering fusion显示文摘The goal of this paper is to give a survey of the previous works on the globally optimal distributed Kalman filtering fusion with classical and nonclassical dynamic systems. Then, we summarize some of our recent results on nonclassical and unideal dynamic systems, including dynamic systems with feedback and cross-correlated sensor measurement noises, dynamic systems with random parameter matrices, and dynamic systems with out-of-sequence or asynchronous measurements. The global optimality in this paper means that the distributed Kalman filtering fusion is exactly equal to the corresponding centralized optimal Kalman filtering fusion. Therefore, not only all of the proposed fusion algorithms here are distributed, but performance as good as that of the corresponding optimal centralized fusion algorithms is achieved. There also exist many papers for other fusion optimality (e.g., the optimal convex linear estimation/compression fusion) discussion, which are not involved in this paper. | SHEN XiaoJing LUO YingTing ZHU YunMin SONG EnBin | 2012 | Science China(Information Sciences)2012,55,3: | 6 |
| 5 | Different contribution of SBP and DBP variability to vascular events in patients with stroke显示文摘Background High blood pressure variability(BPV)is a novel risk factor for cardiovascular disease.However,the heterogeneity of systolic blood pressure variability(SBPV)and diastolic blood pressure variability(DBPV)for different vascular events remains unclear.This study aims to investigate whether SBPV or DBPV has different contribution to vascular events in patients with acute ischaemic stroke(IS)or transient ischaemic attack(TIA).Methods Data from the BOSS(blood pressure and clinical outcome in TIA or IS)study were examined for vascular events at 3-month and 1-year follow-up.BPV was defined as the SD and coefficient of variation(CV)of day-to day measurements within 3 months after IS/TIA.Vascular events include cardiovascular events(myocardial infarction,unstable angina,cardiac death and congestive heart failure)and cerebrovascular events(ischaemic or haemorrhagic stroke).Logistic regression model was used to test the associations between BPV and vascular events.results Of 2325 patients with IS or TIA,103(4.43%)experienced a recurrent stroke and 64(2.75%)had cardiovascular events within 3 months.Day-to day SBPV was only associated with stroke recurrence(BPVSD:OR,1.72,95%CI 1.09 to 2.71;BPVCV:1.86,95%CI 1.19 to 2.92),but not cardiovascular events(BPVSD:1.67,95%CI 0.94 to 2.94;BPVCV:1.51,95%CI 0.86 to 2.64).However,DBPV seems to be related to both stroke(BPVSD:1.60,95%CI 1.02 to 2.49;BPVCV:1.53,95%CI 0.99 to 2.37)and cardiovascular events(BPVSD:2.48,95%CI 1.37 to 4.48;BPVCV:1.92,95%CI 1.09 to 3.36).Similar results were found at 1 year.Conclusions For patients with IS/TIA,stroke recurrence was associated with both SBPV and DBPV;however,cardiovascular events seem to be only related to DBPV. | Liye Dai Aichun Cheng Xiwa Hao Jie Xu Yingting Zuo Anxin Wang Xia Meng Hao Li Yilong Wang Xingquan Zhao Yongjun Wang | 2020 | Stroke & Vascular Neurology2020,5,2: | 6 |
| 6 | microRNA-21a-5p/PDCD4 axis regulates mesenchymal stem cell-induced neuroprotection in acute glaucoma显示文摘间充质的干细胞(MSC ) 被表明了为许多神经病学的疾病有有希望的治疗学的好处;然而,内在的机制糟糕被理解。这里,我们显示出 MSC 的那 intravitreal 注入在尖锐绿内障的一个老鼠模型的支持的网膜的中心细胞(RGC ) 幸存与 microglial 激活的重要抑制, TNF- , IL-1,和反应的氧种类的生产,以及 caspase-8 和 caspase-3 激活。在 vitro, MSC 禁止了两 caspase-8-mediated RGC apoptosis 和 microglial 激活,部分经由 stanniocalcin 的行动 1 (STC1 ) 。而且,我们发现了那 microRNA-21a-5p (miR-21 ) 和它的目标, PDCD4,为 STC1 生产和在 vitro 并且在 vivo 的 MSC 的 neuroprotective 性质是必要的。重要地, miR-21 overexpression 或 PDCD4 尖锐绿内障上的击倒的扩充调停 MSC 的 neuroprotective 效果。miR-21/PDCD4 轴由导致 MSC 分泌施加 neuroprotective 的 STC1 和另外的因素的以前未被认出的 neuroprotective 机制完成的这些数据热点。因此, modulating miR-21/PDCD4 轴可能是为尖锐绿内障和另外的神经病学的疾病的临床的处理的有希望的策略。 | Wenru Su Zuohong Li Yu Jia Yingting Zhu Wenjia Cai Peixing Wan Yingying Zhang Song Guo Zheng Yehong Zhuo | 2017 | Journal of Molecular Cell Biology2017,9,4: | 5 |
| 7 | Hypoxia-mimicking 3D bioglass-nanoclay scaffolds promote endogenous bone regeneration显示文摘Large bone defect repair requires biomaterials that promote angiogenesis and osteogenesis.In present work,a nanoclay(Laponite,XLS)-functionalized 3D bioglass(BG)scaffold with hypoxia mimicking property was prepared by foam replication coupled with UV photopolymerization methods.Our data revealed that the incorporation of XLS can significantly promote the mechanical property of the scaffold and the osteogenic differentiation of human adipose mesenchymal stem cells(ADSCs)compared to the properties of the neat BG scaffold.Desferoxamine,a hypoxia mimicking agent,encourages bone regeneration via activating hypoxia-inducible factor-1 alpha(HIF-1α)-mediated angiogenesis.GelMA-DFO immobilization onto BG-XLS scaffold achieved sustained DFO release and inhibited DFO degradation.Furthermore,in vitro data demonstrated increased HIF-1αand vascular endothelial growth factor(VEGF)expressions on human adipose mesenchymal stem cells(ADSCs).Moreover,BG-XLS/GelMA-DFO scaffolds also significantly promoted the osteogenic differentiation of ADSCs.Most importantly,our in vivo data indicated BG-XLS/GelMA-DFO scaffolds strongly increased bone healing in a critical-sized mouse cranial bone defect model.Therefore,we developed a novel BG-XLS/GelMA-DFO scaffold which can not only induce the expression of VEGF,but also promote osteogenic differentiation of ADSCs to promote endogenous bone regeneration. | Xiao Zheng Xiaorong Zhang Yingting Wang Yangxi Liu Yining Pan Yijia Li Man Ji Xueqin Zhao Shengbin Huang Qingqing Yao | 2021 | Bioactive Materials2021,6,10: | 4 |
| 8 | DISTRIBUTED KALMAN FILTERING FUSION WITH PACKET LOSS OR INTERMITTENT COMMUNICATIONS FROM LOCAL ESTIMATORS TO FUSION CENTER显示文摘当过程噪音确实存在时,这份报纸考虑从本地评估者与被动的包损失或创始的断断续续的通讯过滤熔化到熔化中心的分布式的 Kalman。当本地估计没太多被失去时,就算过程噪音确实存在,作者建议等价于与完全的通讯过滤熔化的相应集中的 Kalman 的一个最佳的分布式的熔化算法。当这个条件没满足时,基于上述全球 optimality 结果和传感器数据压缩,作者建议一个非最优的分布式的熔化算法。就算过程噪音力量相当大,这个非最优的算法仍然比标准更好工作很好并且显著地的数字例子表演散布了过滤熔化题目到包损失的 Kalman。 | Yingting LUO Yunmin ZHU Xiaojing SHEN Enbin SONG | 2012 | Journal of Systems Science & Complexity2012,25,3: | 3 |
| 9 | CO_(2) combining power and outcomes in patients with acute ischaemic stroke or transient ischaemic attack显示文摘Background and purpose The clinical significance of carbon dioxide combining power(CO_(2) CP)in ischaemic cerebrovascular disease is not well established,and the role of CO_(2) CP in the prognosis of acute ischaemic stroke(AIS)or transient ischaemic attack(TIA)has not been reported.The objective of the study was to investigate the associations between CO2CP and clinical outcomes in patients with AIS or TIA.Methods Data were derived from the China National Stroke Registry III.Patients were classified into five groups by quintiles of CO_(2) CP levels and three groups according to the normal range of CO_(2)CP(23-29 mmol/L).Multivariable Cox and logistic regressions were adopted to explore the associations of CO_(2) CP levels with all-cause death and poor functional outcomes(modified Rankin Scale(mRS)3-6/2-6)at 3 months and 1 year.Results Among 9531 patients included in the study,the median(IQR)CO_(2) CP was 24.9(23.0-27.0)mmol/L.After adjustment for potential confounders,patients in the first CO_(2) CP quintile(21.1-23.3 mmol/L)had higher risk of all-cause death and poor functional outcomes(mRS score of 3-6/2-6)(HR or OR with 95% CI 2.37(1.32 to 4.25),1.49(1.20 to 1.83)and 1.21(1.03 to 1.42),respectively)compared with those in the fourth quintile.Similar results were found for outcomes at 1 year.Furthermore,all associations were also significant when CO_(2) CP was<23 mmol/L compared with CO_(2) CP of 23-29 mmol/L.Conclusions Decreased CO_(2) CP was associated with high risk of all-cause death and poor functional outcomes in patients with AIS or TIA. | Anxin Wang Xue Tian Hongqiu Gu Yingting Zuo Xia Meng Wei Lv Hao Li Yongjun Wang | 2021 | Stroke & Vascular Neurology2021,6,2: | 2 |
| 10 | Digital medical education empowered by intelligent fabric space显示文摘Medical education plays an important role in promoting the development of global medical science.Nevertheless,the intrinsic gap existing between institutional medical teaching and practical clinical tasks causes low education efficiency and students’weak initiative.Recent developments of sensing fabric and embedded computing,along with the advances in artificial intelligence(AI)and digital twin technology are paving the way for the transformation of medical research towards digitization.In this work,we present an intelligent fabric space based on novel functional fabric materials and digital twin networking enabled by 5G and internet of things(IoT)technologies.In this space,medical students can learn knowledge with collaborative mapping of the digital and real world,cyber-physical interaction and real-time tactile feedback.And the proposed service system will evaluate and feedback students’operational behaviors to improve their experimental skills.We provide four typical applications of intelligent fabric space for medical education,including medical education training,health and behavior tracking,operation playback and reproduction,as well as medical knowledge popularization.The proposed intelligent fabric space has the potential to promote innovative technologies for training cutting-edge medical students by effective and efficient ways. | Min Chen Rui Wang Rui Wang Yingting Zhou Zicheng He Xiaojuan Liu Muyao He Jiaxi Wang Chaolin Huang Huamin Zhou Ping Hong Chong Hou Ning Zhou Dingyu Zhang Guangming Tao | 2022 | National Science Open2022,1,1: | 2 |
| 11 | Integrated optimization methods in multisensor decision and estimation fusion显示文摘This paper presents a significant integrated optimization point of view behind the following three successful decision and estimation fusion results: 1) a unified fusion rule for networked sensor decision systems; 2) optimal sensor data quantization for estimation fusion and 3) integrated multi-target data association tracking systems. More precisely speaking, the integrated optimization method in 1) derives a unified objective function optimizing only sensor rules given a unified fusion rule; the method in 2) derives a unified objective function optimizing both the sensor quantization rule and the final estimation in the MSE sense, and the method in 3) integrates all associated targets and their valid observations into a whole random measurement matrix dynamic system so that the optimal random matrix Kalman filtering can be applied to estimate the states of all associated targets. | LUO YingTing SHEN XiaoJing ZHU YunMin | 2012 | Science China(Information Sciences)2012,55,3: | 2 |
| 12 | Sea State Bias Estimation with Least Absolute Shrinkage and Selection Operator(LASSO)显示文摘With the sea-level rising,the measurement of sea surface height(SSH) is attracting more and more attention in the area of oceanography.Satellite radar altimeter is usually used to measure the SSH.However,deviation between the measured value and the actual one always exists.Among others,the sea state bias(SSB) is a main reason to cause the deviation.In general,one needs to estimate SSB first to correct the measured SSH.Currently,existing SSB estimation methods more or less have shortcomings,such as with many parameters,high prediction error and long training time.In this paper,we introduce an effective and efficient linear model called LASSO to the SSB estimation.The LASSO algorithm minimizes the residual sum of squares under the condition that the sum of the absolute values of each coefficient is less than a certain constant.In the implementation of LASSO,we use the significant wave height and wind speed to fit the LASSO model.Hence,the applied model has only 3 parameters,corresponding to the two inputs and a bias.Experimental results on the data of JASON-2,JASON-3,T/P and HY-2 radar altimetry show that LASSO performs better than geophysical data records(GDR) and ordinary least squares(OLS) estimator.Moreover,from the running time,we can see that LASSO is very efficient. | ZHONG Guoqiang LIU Benxiu GUO Yingting MIAO Hongli | 2018 | Journal of Ocean University of China2018,17,5: | 2 |
| 13 | Polydimethylsiloxane (PDMS) Composite Membrane Fabricated on the Inner Surface of a Ceramic Hollow Fiber: From Single-Channel to Multi-Channel显示文摘The fabrication of a separation layer on the inner surface of a hollow fiber (HF) substrate to form an HF composite membrane offers exciting opportunities for industrial applications, although challenges remain. This work reports on the fabrication of a polydimethylsiloxane (PDMS) composite membrane on the inner surface of a single-channel or multi-channel ceramic HF via a proposed coating/crossflow approach. The nanostructures and transport properties of the PDMS HF composite membranes were optimized by controlling the polymer concentration and coating time. The morphology, surface chemistry, interfacial adhesion, and separation performance of the membranes were characterized by fieldemission scanning electron microscope (FE-SEM), attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy, the nano-indentation/scratch technique, and pervaporation (PV) recovery of bio-butanol, respectively. The formation mechanism for the deposition of the PDMS layer onto the inner surface of the ceramic HF was studied in detail. The optimized inner surface of the PDMS/ceramic HF composite membranes with a thin and defect-free separation layer exhibited a high flux of ~1800 gm-2h-1 and an excellent separation factor of 35–38 for 1 wt% n-butanol/water mixtures at 60 C. The facile coating/cross-flow methodology proposed here shows great potential for fabricating inner-surface polymer-coated HFs that have broad applications including membranes, adsorbents, composite materials, and more. | Ziye Dong Haipeng Zhu Yingting Hang Gongping Liu Wanqin Jin | 2020 | Engineering2020,6,1: | 2 |
| 14 | Loss-of-function of KMT5B leads to neurodevelopmental disorder and impairs neuronal development and neurogenesis显示文摘Autism spectrum disorder(ASD)is a group of neurodevelopmental disorders that cause severe social,communication,and behavioral problems.Recent studies show that the variants of a histone methyltransferase gene KMT5B cause neurodevelopmental disorders(NDDs),including ASD,and the knockout of Kmt5b in mice is embryonic lethal.However,the detailed genotype-phenotype correlations and functional effects of KMT5B in neurodevelopment are unclear.By targeted sequencing of a large Chinese ASD cohort,analyzing published genome-wide sequencing data,and mining literature,we curated 39 KMT5B variants identified from NDD individuals.A genotype-phenotype correlation analysis for 10 individuals with KMT5B pathogenic variants reveals common symptoms,including ASD,intellectual disability,languages problem,and macrocephaly.In vitro knockdown of the expression of Kmt5b in cultured mouse primary cortical neurons leads to a decrease in neuronal dendritic complexity and an increase in dendritic spine density,which can be rescued by expression of human KMT5B but not that of pathogenic de novo missense mutants.In vivo knockdown of the Kmt5b expression in the mouse embryonic cerebral cortex by in utero electroporation results in decreased proliferation and accelerated migration of neural progenitor cells.Our findings reveal essential roles of histone methyltransferase KMT5B in neuronal development,prenatal neurogenesis,and neuronal migration. | Guodong Chen Lin Han Senwei Tan Xiangbin Jia Huidan Wu Yingting Quan Qiumeng Zhang Bin Yu Zhengmao Hu Kun Xia Hui Guo | 2022 | Journal of Genetics and Genomics2022,49,9: | 1 |
| 15 | Micro-FTIR spectroscopy of liptinite macerals in coal显示文摘 | Guo Yingting Bustin R Marc | 1998 | International Journal of Coal Geology1998,36,3: | 1 |
| 16 | Micro-FTIR spectroscopy of liptinite macerals in coal显示文摘 | Yingting Guo R.Marc Bustin | 1998 | International Journal of Coal Geology1998,,3: | 1 |
| 17 | Phenoland2-naphtholpmduction by toluene 4-monooxygenases using an aqueous/dioctyl phthalate system 显示文摘 | YingT BentleyWE WoodTK | 2005 | AppliedMicrobiologyandBiotechnology2005,68,5: | 1 |
| 18 | Chinese herbal medicine for intestinal Jiling in treatment of diarrhea predominant irritable bowel syndrome randomized controlled clinical study显示文摘 | Shao Gang Huang Li Yingting | 2013 | Guangzhou University of traditional Chinese medicine2013,30,15: | 1 |
| 19 | Endemism in the Flora of China--Studies on the Endemism Genera[J]显示文摘 | YingTS(应俊生) ZhangZS(张志松) | 1984 | 植物分类学报1984,22,4: | 1 |
| 20 | Cyclooxygenase-2 expression and prostanoid biogenesis reflect clinical phenotype in human colorectal fibreblast strains 显示文摘 | Yingting Zhu Ping Hua Peter Lance | 2003 | Cancer Research2003,1563,2: | 1 |