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| 1 | Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms显示文摘刺激干扰素的基因 56 (ISG56 ) 家庭成员在堵住病毒的复制并且然而,调整细胞的功能起重要作用他们的内在的分子的机制大部分是不清楚的。这里,我们在场 ISG54 的水晶结构,有新奇 RNA 有约束力的结构的 ISG56 家庭蛋白质。结构证明 ISG54 单体有 9 tetratricopeptide 像重复的主题和伙伴到形成交换域的 dimers。C 终端部分合拢进超级螺旋状的结构并且在它的内部表面上有一条广泛地断然控告的核苷酸绑定隧道。EMSA 结果证明 ISG54 明确地绑在一些 RNA,例如 adenylate uridylate (AU ) 富有的 RNA,与或没有 5 ′triphosphorylation。Mutagenesis 和功能的研究证明这个 RNA 有约束力的能力对它的抗病毒的活动重要。我们的结果建议位于这干扰素可诱导的基因的抗病毒的活动下面的新机制 56 家庭成员。 | Zhenlin Yang Huanhuan Liang Qian Zhou Ying Li Haiwei Chen Wen Ye Danying Chen Joy Fleming Hongbing Shu Yingfang Liu | 2012 | Cell Research2012，22，9： | 8 |
| 2 | Difficult and complicated oral ulceration:an expert consensus guideline for diagnosis显示文摘The complexity of oral ulcerations poses considerable diagnostic and therapeutic challenges to oral specialists.The expert consensus was conducted to summarize the diagnostic work-up for difficult and complicated oral ulcers,based on factors such as detailed clinical medical history inquiry,histopathological examination,and ulceration-related systemic diseases screening.Not only it can provide a standardized procedure of oral ulceration,but also it can improve the diagnostic efficiency,in order to avoid misdiagnosis and missed diagnosis. | Xin Zeng Xin Jin Liang Zhong Gang Zhou Ming Zhong Wenmei Wang Yuan Fan Qing Liu Xiangmin Qi Xiaobing Guan Zhimin Yan Xuemin Shen Yingfang Wu Lijie Fan Zhi Wang Yuan He Hongxia Dan Jiantang Yang Hui Wang Dongjuan Liu Hui Feng Kai Jiao Qianming Chen | 2022 | International Journal of Oral Science2022，14，2： | 2 |
| 3 | Composite rock-breaking of high-pressure CO_(2)jet&polycrystallinediamond-compact(PDC)cutter using a coupled SPH/FEM model显示文摘CO_(2) drilling is a promising underbalance drilling technology with great advantages,such as lower cutting force,intense cooling and excellent lubrication.However,in the underbalance drilling,the mechanism of the coupling CO_(2) jet and polycrystalline-diamond-compact(PDC)cutter are still unclear.Whereby,we established a coupled smoothed particle hydrodynamics/finite element method(SPH/FEM)model to simulate the composite rock-breaking of high-pressure CO_(2) jet&PDC cutter.Combined with the experimental research results,the mechanism of composite rock-breaking is studied from the perspectives of rock stress field,cutting force and jet field.The results show that the composite rock-breaking can effectively relieve the influence of vibration and shock on PDC cutter.Meanwhile,the high-pressure CO_(2) jet has a positive effect on carrying rock debris,which can effectively reduce the temperature rising and the thermal wear of the PDC cutter.In addition,the effects of CO_(2) jet parameters on composite rock-breaking were studied,such as jet impact velocity,nozzle diameter,jet injection angle and impact distance.The studies show that when the impact velocity of the CO_(2) jet is greater than 250 m/s,the CO_(2) jet could quickly break the rock.It is found that the optimal range of nozzle diameter is 1.5–2.5 mm,the best injection angle of CO_(2) jet is 60,the optimal impact distance is 10 times the nozzle diameter.The above studies could provide theoretical supports and technical guidance for composite rock-breaking,which is useful for the CO_(2) underbalance drilling and drill bit design. | Can Cai Pei Zhang Daping Xu Xianpeng Yang Yingfang Zhou | 2022 | International Journal of Mining Science and Technology2022，32，5： | 2 |
| 4 | Facile synthesis and electrochemical properties of layered Li[Ni1/3Mn1/3Co1/3]O2 as cathode materials for lithium-ion batteries显示文摘 | Yingfang ZHU Jingwei YOU Haifu HUANG Guangxu LI Wenzheng ZHOU Jin GUO | 2017 | Frontiers of Materials Science2017，11，2： | 2 |
| 5 | 548 cases of gestational thyroid function screening indications and subclinical JiaJian effect on pregnancy outcome analysis 显示文摘 | sun smile zhang lei hui - xia Yang Zhou Yingfang wei - jie sun | 2014 | Chinese journal of obstetrics and gynecology clinical2014，01，： | 1 |
| 6 | A wide spectrum of variably periictal MRI abnormalities induced by a single or a cluster of seizures显示文摘 | Tao Xiang Guoliang Li Yingfang Liang Jinxia Zhou | 2014 | Journal of the Neurological Sciences . 2014 (1-2)2014，，1： | 1 |
| 7 | Theoretical calculation of high-pressure CO_(2)jet in cases of composite rock-breaking based on span-wagner equation of state显示文摘Although several theoretical calculation methods for high-pressure jet are available,there is currently no theoretical model for the high-pressure CO_(2)jet based on the high-precision equation of state(EOS).To investigate the flow field of the high-pressure CO_(2)jet in cases of the composite rock-breaking under the high-pressure CO_(2)Jet and PDC cutter,a semi-analytical approach of the high-pressure CO_(2)jet is developed based on the Span-Wagner EOS and CO_(2)jet theory.The semi-analytical calculations and the physical property calculations under the action of the high-pressure CO_(2)jet are conducted with consideration of the jet pressure,the jet distance,the nozzle diameter and the jet angle.The results indicate that the distribution of the physical properties calculated by the semi-analytical approaches is similar to that obtained by experimental monitoring and numerical simulation,which indicates that the calculation method of the high-pressure CO_(2)jet presented in this paper is effective and reliable.The properties of the CO_(2)jet obtained by the theoretical calculation see a significant difference between the initial region and the jet impact region.At the temperature of 300 K,the increase of the initial pressure can effectively increase the impact force and the cooling ability of the jet.The proportion of the jet core lengths in the jet on the axis increases with the increase of the ratio of the nozzle diameter to the jet length,accompanied with the increase of the impact force of the jet.The increase of the jet angle can effectively increase the impacting force of the jet,but hampers the fluid diffusion.The study combines the theoretical calculation of the jet with the calculation of the physical properties of the high-pressure CO_(2),for comprehensively understanding the CO_(2)jet field in the composite rock-breaking under the action of the high-pressure CO_(2)jet and PDC cutter.This theoretical calculation of the CO_(2)jet based on the high-precision EOS provides an option for the convenient calculation of the CO_(2)drilling in practical engineering. | Xian-peng Yang Can Cai Xiao-hua Chen Pei Zhang Xin Zeng Chi Peng Yingfang Zhou | 2022 | Journal of Hydrodynamics2022，34，5： | 1 |
| 8 | The blue light receptor CRY1 interacts with GID1 and DELLA proteins to repress gibberellin signaling and plant growth显示文摘Improvements in plant architecture,such as reduced plant height under high-density planting,are important for agricultural production.Light and gibberellin(GA)are essential external and internal cues that affect plant architecture.In this study,we characterize the direct interaction of distinct receptors that link light and GA signaling in Arabidopsis(Arabidopsis thaliana)and wheat(Triticum aestivum L.).We show that the light receptor CRY1 represses GA signaling through interaction with all five DELLA proteins and promotion of RGA protein accumulation in Arabidopsis.Genetic analysis shows that CRY1-mediated growth repression is achieved by means of the DELLA proteins.Interestingly,we find that CRY1 also directly interacts with the GA receptor GID1 to competitively inhibit the GID1-GAI interaction.We also show that overexpression of TaCRY1a reduces plant height and coleoptile growth in wheat and that TaCRY1a interacts with both TaGID1 and Rht1 to competitively attenuate the TaGID1-Rht1 interaction.Based on these findings,we propose that the photoreceptor CRY1 competitively inhibits the GID1-DELLA interaction,thereby stabilizing DELLA proteins and enhancing their repression of plant growth. | Baiqiang Yan Zongju Yang Guanhua He Yexing Jing Huixue Dong Lan Ju Yunwei Zhang Yingfang Zhu Yun Zhou Jiaqiang Sun | 2021 | Plant Communications2021，2，6： | 1 |
| 9 | Research progresson denitrifying microbial fuel cell 显示文摘 | Tan Biao Zi Yingfang Zhou Hua | 2012 | Envi- ronmental Science and technology2012，35，1： | 1 |
| 10 | SEMG-based fighter pilot muscle fatigue analysis and operation performance research显示文摘Fatigue has a tremendously adverse impact on pilot performance.This study aims to explore the Biceps Brachii(BB),Rectus Femoris(RF),Flexor Carpi Radialis(FCR),and Tibialis Anterior(TA)activities of fighter pilots in the early and late combat stages,and the target hitting time.A total of 13 volunteers were recruited to conduct simulated combats inside a real fighter cockpit.The surface Electromyography(sEMG)was collected from all volunteers in the initial and final 20s of flight,and the target hitting time during three simulated combats was recorded.The root mean square(RMS)values of right BB and TA were significantly higher than the left side values(p<0.001),while insignificant differences were found in the RMS values between the bilateral RF and FCR.Compared to the early flight period,the median frequency(MF)values of BB and TA were significantly lower during the late flight period,and the RMS values were significantly higher(p<0.047).Contrastively,the RMS values of FCR and RF differed insignificantly during the late flight period.Regarding the target hitting time,a significant difference was noted between task 1 and rask3.Subjects exhibit varying levels of muscle fatigue for different muscle groups before and after the flight.The muscle fatigue levels are asymmetrical on the left and right sides.Muscle fatigue might reduce the pilots'operational ability.This study provides a reference for fighter pilot fatigue protection and treatment. | Biyun Zhou Bo Chen Huijuan Shi Lihao Xue Yingfang Ao Li Ding | 2022 | Medicine in Novel Technology and Devices2022，，4： | 0 |
| 11 | Influence of charge transport layer on the crystallinity and charge extraction of pure tin-based halide perovskite film显示文摘As one of the most compelling photovoltaic devices, halide perovskite (PVK) solar cells have achieved a new surprising record power conversion efficiency (PCE) of 25.8%in 2021 [1]. This demonstrates the great potential of halide PVK solar cells as a highly competitive substitute to replace silicon-based solar cells in the photovoltaic market [2–6]. | Yaohong Zhang Muhammad Akmal Kamarudin Qiao Li Chao Ding Yong Zhou Yingfang Yao Zhigang Zou Satoshi Iikubo Takashi Minemoto Kenji Yoshino Shuzi Hayase Qing Shen | 2022 | Journal of Energy Chemistry2022，31，6： | 0 |
| 12 | Effectiveness of Xiangsha Liujun pills(香砂六君丸)on decreased digestive function in convalescent patients of coronavirus disease 2019:a randomized,double blind,placebo controlled clinical trial显示文摘OBJECTIVE:To evaluate the effectiveness and safety of Xiangsha Liujun pills(香砂六君丸) on the decreased digestive function in patients in the recovery phase of the Coronavirus disease 2019(COVID-19).METHODS:A randomized,double blind,placebo controlled clinical trial was conducted.A total of 200 COVID-19 patients in the recovery phase were included in our study in Ezhou Hospital of Traditional Chinese Medicine.Totally 200 subjects were randomly divided into a treatment group(Xiangsha Liujun pills) and a control group(placebo),with 100 in each group.Subjects took Xiangsha Liujun pills or placebo orally three times a day for two weeks.Three visits were scheduled at week 0(baseline),week 1(the middle of the intervention) and week 2(the end of the intervention) for each eligible patient.The total efficacy rates for improving the Traditional Chinese Medicine(TCM) symptoms(fatigue,poor appetite,abdominal distension and loose stools) and the disappearance rates of symptoms were observed and compared in the treatment and control groups.Adverse events were recorded during the study period.SAS 9.4 was used to analyze the data.RESULTS:A total of 200 patients were included in this study,among which 4 participants withdrew because the drugs did not work.Three patients were excluded for age.Before the treatment,there was no significant difference between the TCM symptoms scores of subjects.After 1 week of treatment,the full analysis set(FAS) showed that the efficacy rates for abdominal distension and loose stools in the treatment group were significantly higher than the control group(P < 0.05).There were no significant differences in the efficacy rates for fatigue and poor appetite between the two groups(P > 0.05).In addition,the disappearance rate of fatigue in the treatment group was significantly higher than the control group(P < 0.05);there were no significant differences between the two groups after treatment in the rates of poor appetite,abdominal distension,and loose stools(P > 0.05).After 2 weeks of treatment,the efficacy rates for fatigue,poor appetite,abdominal distension,and loose stools in the treatment group were significantly higher than the control group(P < 0.05).The disappearance rate of loose stools in the treatment group was significantly higher than the control group(P < 0.05).However,there were no significant differences in the disappearance rates of fatigue,poor appetite,and abdominal distension between the two groups(P > 0.05).No severe adverse events were reported by subjects during the study.CONCLUSIONS:This clinical study confirmed that Xiangsha Liujun pills can effectively improve the symptoms related to the decreased digestive function in COVID-19 convalescent patients. | ZHANG Yuehong SHAO Xianzhi ZHAO Qianlong ZHAN Hualong ZHANG Jianhua DU Sisi CHEN Jing LIU Yingfang ZHOU Haiwang CHEN Xinsheng HONG Ying LIAN Fengmei TONG Xiaolin BA Yuanming | 2023 | Journal of Traditional Chinese Medicine2023，43，3： | 0 |
| 13 | METHODS FOR IDENTIFYING SUB-REGIONAL MATERIAL PARAMETERS OF CONCRETE DAMS USING MODAL DATA显示文摘Methods for identifying sub-regional material parameters of concrete dams using in-complete modal data are presented.With the measurements of the first frequency and incompletemode shape,identification methods were built by both the output error approach and the minimumdeviation approach.The minimum deviation approach was introduced as physical constraints tothe output error approach,allowing the output error-minimum deviation coupled approach to bedeveloped.The simulated annealing-simplex shape algorithm was applied to solve the identifi-cation models.Numerical simulations were carried out with noisy incomplete measurements toillustrate the robustness of the methods. | Feng Xin Zhou Jing Fan Yingfang | 2003 | Acta Mechanica Solida Sinica2003，16，1： | 0 |
| 14 | Effect of mixing lard with soybean oil in cooking on hepatic antioxidative ability and renal metabolic activity显示文摘A simulate daily oriental dietary pattern(a blend of lard and soybean oil)was performed in this research to investigate influence on liver and kidney function.Sixty mice were randomly divided into 6 groups with diets of different fat added oils respectively for 12 weeks.Malondialdehyde and uric acid contents in mice fed with blended oil were significantly lower than in those fed only with soybean oil and lard due to the improved activities of antioxidant enzymes.Daily use of a blend of lard with soybean oil significantly increased antioxidant capacity,reduced lipid peroxidation of liver and serum uric acid production,thus protected liver and renal function.It also suggests that the oriental dietary pattern might reduce the risk of gout. | Yingfang Zhou Xin Li Linyu Zhang Haisi Xiao Sisi Yan Lixin Wen Ji Wang | 2020 | Oil Crop Science2020，5，1： | 0 |
| 15 | Property of Corroded Concrete under Compressive Uniaxial Loads显示文摘以便学习侵蚀的水泥的压缩性质,加速的腐蚀试验在具体 C30.6 腐蚀剂答案上被执行包括水力的酸液(pH=2 ) ,水力的酸液(pH=3 ) 作为腐蚀剂媒介被使用。包括 111 个标本,腐蚀试验的 6 系列被执行。所有侵蚀的标本的机械性质分别地被测试。侵蚀的标本的压缩性质(例如压缩强度,压力紧张关系,有弹性的模量等等) 被完成。作为损坏索引拿力量降级比率和紧张精力损失,侵蚀的水泥的压缩性质上的腐蚀答案的效果详细被讨论。在损坏索引和标本的腐蚀状态之间的关系被完成。 | FAN Yingfang HU Zhiqiang ZHOU Jing LI Xin | 2008 | Journal of Wuhan University of Technology(Materials Science)2008，23，2： | 0 |
| 16 | Factors influencing methane diffusion behaviors in micro-nano coal pores: a comprehensive study显示文摘Gas diffusion in the coal matrix plays a significant role in forecasting the production performance of coalbed methane(CBM)wells.To better understand methane diffusion behavior,a systematic study was performed on various rank coals with vitrinite reflectance(Ro,m)ranging from 0.46%to 2.79%.Multiple experiments,including coal petrographic analysis,field emission scanning electron microscopy(FESEM),low-temperature N2 adsorption/desorption,and mercury intrusion porosimetry(MIP),were conducted to quantitatively characterize the multiscale micro-nano pore system in different rank coals,which showed that the pore structure of coals exhibited a multimodal pore size and volume distribution.Isothermal adsorption-diffusion experiments using the volumetric method were also performed to understand the methane diffusion characteristics in the micro-nano pores of the coal reservoir.The applicability of the multiporous diffusion model is verified,and methane diffusion in the multi-scale pores of coal reservoirs exhibits the characteristics of early fast diffusion,transitional diffusion in the medium term,and slow diffusion in the later period.In addition,the factors affecting methane diffusion in coals were systematically analyzed,and gray relational analysis(GRA)was employed to analyze and identify the importance of these factors on methane diffusion.The results show the impact ranking of factors,in order from the most important to the least:particle size>moisture>surface area>pore volume>pressure>coal rank>temperature in all of three diffusion stages.These findings are helpful for forecasting production performance and enhancing the production efficiency of CBM. | Xianglong FANG Dameng LIU Yingfang ZHOU Xiaobo LIU Yidong CAI | 2023 | Frontiers of Earth Science2023，17，1： | 0 |
| 17 | P-wave and S-wave response of coal rock containing gas-water with different saturation: an experimental perspective显示文摘The acoustic response of gas and/or water saturated coal rock is fundamental for establishing the correspondence between the physical properties of the coal reservoir and the characteristics of the well-logging response,which is the technology essential for the geophysical exploration of coalbed methane(CBM).This acoustic response depends on water(Sw)and gas(Sg)saturation among other factors.In this study,we performed acoustic tests on dry and different gas-water saturated coal samples with different degrees of metamorphism and deformation,collected from several coal mining areas in China.These tests enabled us to analyze the influence of coal type and gas-water saturation on the acoustic response of CBM formations.Our results show that the acoustic velocity of P-wave and S-wave(Vp and Vs,respectively),and the relative anisotropy of and Vs,increased with increasing vitrinite reflectance,density,Vp and Sw.WithSw increasing from 0 to 100%,the growth rate of the acoustic velocity decreased with increasing vitrinite reflectance.The Vp/Vs ratio of tectonic coal was generally higher than that of primary coal.The growth rate of the relative anisotropy in tectonic coal was markedly higher than that in primary coal. | Dameng LIU Lijing LI Zheng ZHAO Wei CHEN Yidong CAI Yongkai QIU Yingfang ZHOU | 2023 | Frontiers of Earth Science2023，17，1： | 0 |
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