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| 1 | Efficacy of adjuvant XELOX and FOLFOX6 chemotherapy after D2 dissection for gastric cancer显示文摘AIM: To compare the efficacy of capecitabine and oxaliplatin (XELOX) with 5-fluorouracil, folinic acid and oxaliplatin (FOLFOX6) in gastric cancer patients after D2 dissection. METHODS: Between May 2004 and June 2010, patients in our gastric cancer database who underwent D2 dissection for gastric cancer at the First Affiliated Hospital of Sun Yat-Sen University were retrospectively analyzed. A total of 896 patients were enrolled into this study according to the established inclusion and exclusion criteria. Of these patients, 214 received the XELOX regimen, 48 received FOLFOX6 therapy and 634 patients underwent surgery only without chemotherapy. Overall survival was compared among the three groups using Cox regression and propensity score matchedpair analyses. RESULTS: Patients in the XELOX and FOLFOX6 groups were younger at the time of treatment (median age 55.2 years; 51.2 years vs 58.9 years), had more undifferentiated tumors (70.1%; 70.8% vs 61.4%), and more lymph node metastases (80.8%; 83.3% vs 57.7%), respectively. Overall 5-year survival was 57.3% in the XELOX group which was higher than that (47.5%) in the surgery only group (P = 0.062) and that (34.5%) in the FOLFOX6 group (P = 0.022). Multivariate analysis showed that XELOX therapy was an independent prognostic factor (hazard ratio = 0.564, P < 0.001). After propensity score adjustment, XELOX significantly increased overall 5-year survival compared to surgery only (58.2% vs 44.2%, P = 0.025) but not compared to FOLFOX6 therapy (48.5% vs 42.7%, P = 0.685). The incidence of grade 3/4 adverse reactions was similar between the XELOX and FOLFOX6 groups, and more patients suffered from hand-foot syndrome in the XELOX group (P = 0.018). CONCLUSION: Adjuvant XELOX therapy is associated with better survival in patients after D2 dissection, but does not result in a greater survival benefit compared with FOLFOX6 therapy. | Ying Wu Zhe-Wei Wei Yu-Long He Roderich E Schwarz David D Smith Guang-Kai Xia Chang-Hua Zhang | 2013 | World Journal of Gastroenterology2013，19，21： | 14 |
| 2 | Panda X-III: Searching for neutrinoless double beta decay with high pressure ^(136)Xe gas time projection chambers显示文摘Searching for the neutrinoless double beta decay(NLDBD)is now regarded as the topmost promising technique to explore the nature of neutrinos after the discovery of neutrino masses in oscillation experiments.Panda X-III(particle and astrophysical xenon experiment III)will search for the NLDBD of136Xe at the China Jin Ping Underground Laboratory(CJPL).In the first phase of the experiment,a high pressure gas Time Projection Chamber(TPC)will contain 200 kg,90%136Xe enriched gas operated at10 bar.Fine pitch micro-pattern gas detector(Microbulk Micromegas)will be used at both ends of the TPC for the charge readout with a cathode in the middle.Charge signals can be used to reconstruct the electron tracks of the NLDBD events and provide good energy and spatial resolution.The detector will be immersed in a large water tank to ensure~5 m of water shielding in all directions.The second phase,a ton-scale experiment,will consist of five TPCs in the same water tank,with improved energy resolution and better control over backgrounds. | Xun Chen Chang Bo Fu Javier Galan Karl Giboni Franco Giuliani Ling Hui Gu Ke Han Xiang Dong Ji Heng Lin Jiang Lai Liu Kai Xiang Ni Hiroki Kusano Xiang Xiang Ren Shao Bo Wang Yong Yang Dan Zhang Tao Zhang Li Zhao Xiang Ming Sun Shou Yang Hu Si Yu Jian Xing Long Li Xiao Mei Li Hao Liang Huan Qiao Zhang Ming Rui Zhao Jing Zhou Ya Jun Mao Hao Qiao Si Guang Wang Ying Yuan Meng Wang Amir N.Khan Neill Raper Jian Tang Wei Wang Jia Ning Dong Chang Qing Feng Cheng Li Jian Bei Liu Shu Bin Liu Xiao Lian Wang Dan Yang Zhu Juan F.Castel Susana Cebri'an Theopisti Dafni Javier G.Garza Igor G.Irastorza Francisco J.Iguaz Gloria Luz ′on Hector Mirallas Stephan Aune Eric Berthoumieux Yann Bedfer Denis Calvet Nicole d'Hose Alain Delbart Maria Diakaki Esther Ferrer-Ribas Andrea Ferrero Fabienne Kunne Damien Neyret Thomas Papaevangelou Franck Sabatie Maxence Vanderbroucke AnDi Tan Wick Haxton Yuan Mei Chinorat Kobdaj Yu-Peng Yan | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，6： | 2 |
| 3 | Narrowband interference miti gatlon in DS-UWB systems显示文摘 | Wang C Ma M Ying R D | 2010 | IEEE Signal Processing Let- ters2010，17，5： | 1 |
| 4 | A maize stress-responsive NAC transcription factor, ZmSNAC1, confers enhanced tolerance to dehydration in transgenic Arabidopsis 显示文摘 | LU M YING S ZHANG D F | 2012 | Plant Cell Reports2012，31，9： | 1 |
| 5 | Microcystin (-LR) affects hormones level of male mice by dama- ging hypothalamic-pituitary system 显示文摘 | WANG X T YING F CHEN Y HAN X D | 2012 | Toxicon2012，59，2： | 1 |
| 6 | Semiparametric analysis of the additive risk model显示文摘 | Ying Z L | 1994 | Biometrika1994，81，： | 1 |
| 7 | High rate of BRAF and RET/PTC dual mutations associated with recurrent papillary thyroid carcinoma显示文摘 | Ying C Thomas D Michelle D | 2009 | Clin Cancer Res2009，15，2： | 1 |
| 8 | Sensitized luminescence from sol-gel-derived SrAl2O4 co-doped with Cu^2+ and Dy^3+ 显示文摘 | YING P LU M K XU D | 2003 | Materials Science and Engineering2003，64，： | 1 |
| 9 | An investigation of dynamic subcarrier allocation in MIMO-OFDMA systems 显示文摘 | PENG Ying ARMOUR S M D McGEEHAN J P | 2007 | IEEE Trans on Vehicular Technology2007，56，5： | 1 |
| 10 | The p300/CBP associated fac-tor: is frequently downregulated in intestinal-type gastric carcinoma andconstitutes a biomarker for clinical outcome显示文摘 | Ying M ZtWang J J Li D W | 2010 | Cancer Biol Ther2010，9，4： | 1 |
| 11 | A fuzzy discrete event system approach to determining optimal HIV/AIDS treatment regimens显示文摘 | Ying H Lin F Macarthur R D | 2006 | IEEE Transactions on Information Technology in Biomedicine2006，10，4： | 1 |
| 12 | Transcriptional regulation of the transforming growth factor-β-inducible mouse germ line Ig ct constant region gene by functional cooperation of smad, CREB, and AML family members 显示文摘 | Ying Z Rik D | 2000 | J Biol Chem2000，22，16： | 1 |
| 13 | Processing of Cu-A1z 03 metal matrix nanocomposite materials by using high energy ball milling 显示文摘 | Ying D Y Zhang D L | 2000 | Materials Science and Engineering A2000，286，1： | 1 |
| 14 | MicroRNA miR-302 inhibits the tumorigenecity of human pluripotent stem cells by coordinate suppression of the CDK2 and CDK4/6 cell cycle pathways显示文摘 | Lin S L Chang D C Ying S Y | 2010 | Cancer Res2010，70，22： | 1 |
| 15 | A macro-scale and semidistributed monthly water balance model to predict climate change impacts in China显示文摘 | Guo S Wang J Xiong L Ying A and Li D | | 0，，： | 1 |
| 16 | Effect of Er∶YAG laser and organic matrix on porosity changes in human enamel显示文摘 | Ying D Chuah G K Hsu C Y S | 2004 | J Dent2004，32，1： | 1 |
| 17 | A comparison of dexmedetomidine and midazolam for sedation in third molar surgery显示文摘 | CHEUNG CW YING CL CHIU WK et d | 2007 | Anaesthesia2007，62，11： | 1 |
| 18 | Predictive value of preimplantationgenetic diagnosis for aneuploidy screening in repeated IVF-ETcycles among women with recurrent implantation failure显示文摘 | Pagidas K Ying Y Keefe D | 2008 | JAssist Reprod Genet2008，25，23： | 1 |
| 19 | Heterogeneous Heck catalysis with palladium-grafted molecular sieves显示文摘 | Mehnert C P Weaver D W Ying J Y | 1998 | Journal of the American Chemical Society1998，120，12： | 1 |
| 20 | Synthesis and evaluation of a new polysiloxane as SAW sensor coatings for DMMP detection显示文摘 | Du X S Ying Z H Jiang Y D | 2008 | Sensors and Actuators B: Chemical2008，134，2： | 1 |
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