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| 1 | Progressive paradoxical sleep deprivation impairs partial memory following learning tasks in rats显示文摘BACKGROUND: Complex learning tasks result in a greater number of paradoxical sleep phases, which can improve memory. The effect of paradoxical sleep deprivation, induced by 'flower pot' technique, on spatial reference memory and working memory require further research. OBJECTIVE: To observe the effect of progressive paradoxical sleep deprivation in rats, subsequent to learning, on memory using the Morris Water Maze. DESIGN, TIME AND SETTING: Controlled observation experiment. The experiment was performed at the Laboratory of Neurobiology, Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Lanzhou University from December 2006 to October 2007. MATERIALS: Twenty-eight, male, Wistar rats, 3-4 months old, were provided by the Experimental Animal Center of Lanzhou University. The Morris Water Maze and behavioral analyses system was purchased from Genheart Company, Beijing, China. METHODS: All animals, according to a random digits table, were randomly divided into paradoxical sleep deprivation, tank control, and home cage control groups. Paradoxical sleep deprivation was induced by the 'flower pot' technique for 72 hours, housing the rats on small platforms over water. Rats in the 'tank control' and 'home cage control' groups were housed either in a tank with large platforms over the water or in normal cages without paradoxical sleep deprivation. MAIN OUTCOME MEASURES: Morris Water Maze was employed for task learning and spatial memory testing. Rats in all groups were placed at six random starting points each day for four consecutive days. Each placement was repeated for two trials; the first trial represented reference memory and the second working memory. Rats in the first trial were allowed to locate the submerged platform within 120 seconds. Data, including swimming distance, escape latency, swimming velocity, percentage of time in correct quarter, and memory scores were recorded and analyzed automatically by behavioral analyses systems for Morris Water Maze. RESULTS: Twenty-eight rats were included in the final analysis, without any loss. In the first trial, between day 2 and 4, escape latency and swimming distance increased significantly in the paradoxical sleep deprivation group compared to the home cage control and tank control groups (P < 0.01); percentage of time in correct quarter and memory scores, however, decreased in the paradoxical sleep deprivation group compared to the home cage control and tank control groups (P < 0.01). The escape latency, swimming distance, percentage of time in correct quarter, and memory scores in the second trial was not significantly different among the three groups (P > 0.05). CONCLUSION: Paradoxical sleep deprivation inhibits spatial reference memory, but not working memory. | Chunmin Zhu Xiangrong Yao Weisheng Zhang Yanfeng Song Yiping Hou | 2008 | Neural Regeneration Research2008，3，6： | 4 |
| 2 | Pyridinic nitrogen enriched porous carbon derived from bimetal organic frameworks for high capacity zinc ion hybrid capacitors with remarkable rate capability显示文摘Aqueous zinc ion hybrid capacitors(ZIHCs)hold great potential for large-scale energy storage applications owing to their high safety and low cost,but suffer from low capacity and energy density.Herein,pyridinic nitrogen enriched porous carbon(nPC)was successfully synthesized via the growth,subsequent annealing and acid etching of bimetal organic frameworks for high capacity and safe ZIHCs with exceptional rate capability.Benefiting from the mesopores for easy ion diffusion,high electrical conductivity enabled by in-situ grown carbon nanotubes matrix and residual metal Co nanoparticles for fast electron transfer,sufficient micropores and high N content(8.9 at%)with dominated pyridinic N(54%)for enhanced zinc ion storage,the resulting nPC cathodes for ZIHCs achieved high capacities of 302 and137 m Ah g^(-1) at 1 and 18 A g^(-1),outperforming most reported carbon based cathodes.Theoretical results further disclosed that pyridinic N possessed larger binding energy of-4.99 eV to chemically coordinate with Zn2+than other N species.Moreover,quasi-solid-state ZIHCs with gelatin based gel electrolytes exhibited high energy density of 157.6 Wh kg^(-1) at 0.69 kW kg^(-1),high safety and mechanical flexibility to withstand mechanical deformation and drilling.This strategy of developing pyridinic nitrogen enriched porous carbon will pave a new avenue to construct safe ZIHCs with high energy densities. | Yao Li Pengfei Lu Ping Shang Lisha Wu Xiao Wang Yanfeng Dong Ronghuan He Zhong-Shuai Wu | 2021 | Journal of Energy Chemistry2021，30，5： | 3 |
| 3 | Assessing the visual quality of green landscaping in rural residential areas: the case of Changzhou, China显示文摘 | Yumin Yao Xiaodong Zhu Yingbi Xu Haiyan Yang Xian Wu Yangfan Li Yanfeng Zhang | | Environmental Monitoring and Assessment0，，： | 1 |
| 4 | Avian Influenza A(H7N9) Virus in a Wild Land Bird in Central China,Late 2015显示文摘Dear Editor,In early 2013,the first case of a human infection with avian influenza A(H7N9)virus was reported in the Yangtze River Delta region of China(Liu et al.2013).Since early2013,a total of 1533 laboratory-confirmed human infections with avian H7N9 viruses have been reported to | Yanfeng Yao Tao Zhang Wenhai Yang Zhiyong Shao Bin He Xiabing Chen Lijun Wu Erguang Jin Haizhou Liu Jianjun Chen Jie Chen | 2018 | Virologica Sinica2018，33，1： | 1 |
| 5 | Im - proved fully vectorial effective index method for pho- tonic crystal fibers: evaluation and enhancement 显示文摘 | Li Yanfeng Yao Yuhong Hu Minglie | 2008 | Applied Optic2008，47，3： | 1 |
| 6 | Oxygen vacancy promoting adsorption property of BiOI microspheres modified with SDS显示文摘BiOI microspheres were synthesized via a facile hydrolytic method with sodium dodecyl sulfate(SDS).The results showed that 8% SDS-BiOI microspheres possessed the homogeneous morphology, larger specific surface area and more oxygen vacancies compared with the pure BiOI. Moreover, the adsorption efficiency of rhodamine B(RhB) and methyl orange(MO) for 8% SDS-BiOI reached almost 96.4% and 79.4%,respectively. It was found that the oxygen vacancy induced by SDS improved adsorption performance of BiOI due to the enhanced electrostatic interaction. | Fenqiang Ma Jingwen Yao Yanfeng Zhang Yu Wei | 2018 | Chinese Chemical Letters2018，29，11： | 1 |
| 7 | Characterization of low-pathogenic H6N6 avian influenza viruses in central China显示文摘 | Yanfeng Yao Huadong Wang Quanjiao Chen Hongbo Zhang Tao Zhang Jianjun Chen Bing Xu Hanzhong Wang Bing Sun Ze Chen | 2013 | Archives of Virology2013，，2： | 1 |
| 8 | Immunization with Cytomegalovirus Envelope Glycoprotein M and Glycoprotein N DNA Vaccines can Provide Mice with Complete Protection against a Lethal Murine Cytomegalovirus Challenge显示文摘Human cytomegalovirus virions contain three major glycoprotein complexes (gC I, II, III), all of which are required for CMV infectivity. These complexes also represent major antigenic targets for anti-viral immune responses. The gC II complex consists of two glycoproteins, gM and gN. In the current study, DNA vaccines expressing the murine cytomegalovirus (MCMV) homologs of the gM and gN proteins were evaluated for protection against lethal MCMV infection in a mouse model. Humoral and cellular immune responses, spleen viral titers, and mice survival and body-weight changes were examined. The results showed that immunization with gM or gN DNA vaccine alone was not able to offer good protection, whereas co-immunization with both gM and gN induced an effective neutralizing antibody response and cellular immune response, and provided mice with complete protection against a lethal MCMV challenge. This study provides the first in vivo evidence that the gC II (gM-gN) complex may be able to serve as a protective subunit antigen for future HCMV vaccine development. | Huadong Wang Yanfeng Yao Chaoyang Huang Quanjiao Chen Jianjun Chen Ze Chen | 2013 | Virologica Sinica2013，28，3： | 1 |
| 9 | Single-dose AAV-based vaccine induces a high level of neutralizing antibodies against SARS-CoV-2 in rhesus macaques显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)is a highly infectious respiratory disease that continues to pose a serious global public health emergency.The disease shows a high infection rate,long incubation period,and rapidly emerging variants,which have led to its rapid spread worldwide(Krammer 2020).Many vaccines have been developed for the control of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the virus responsible for COVID-19,including vaccines based on messenger RNA(mRNA)(Polack et al.2020),viral vectors(Zhu et al.2020),recombinant proteins(Yang et al.2020),and inactivated SARS-CoV-2(Zhang et al.2021). | Dali Tong Mei Zhang Yunru Yang Han Xia Haiyang Tong Huajun Zhang Weihong Zeng Muziying Liu Yan Wu Huan Ma Xue Hu Weiyong Liu Yuan Cai Yanfeng Yao Yichuan Yao Kunpeng Liu Shifang Shan Yajuan Li Ge Gao Weiwei Guo Yun Peng Shaohong Chen Juhong Rao Jiaxuan Zhao Juan Min Qingjun Zhu Yanmin Zheng Lianxin Liu Chao Shan Kai Zhong Zilong Qiu Tengchuan Jin Sandra Chiu Zhiming Yuan Tian Xue | 2023 | Protein & Cell2023，14，1： | 0 |
| 10 | Zinc Complexes Supported by N,N-Dimethylaniline-arylamido Ligands: Synthesis, Characterization and Catalytic Properties for Ring-opening Polymerization of L-Lactide显示文摘 | YAO Wei XUE Yingzhao LIU Tiantian GAO Aihong WANG Yanfeng | 2014 | Chemical Research in Chinese Universities2014，30，1： | 0 |
| 11 | Effect of semi-continuous water washing on the combustion behaviors of agricultural organic solid waste显示文摘Combustion of agricultural organic solid waste(AOSW)was an ideal solution for their resource utilization in view of their massive annual production and great potential for reduction of fossil fuel utilization.However,high alkali and alkaline earth metals(AAEMs)content in the feedstock can arose severe fouling and slagging issues and thus prohibiting its vast utilization.In this study,a semi-continuous water washing method was proposed to preliminarily remove AAEMs from agricultural organic solid waste and its effects on the combustion behaviors of washed solid product were investigated.Results showed that the combustion index S were improved to 2.63×10-6,over 68%of the total ashes were removed from the cotton stalk,and 96.3%,89.0%and 74.7%of K,Na and Mg were effectively removed,respectively.Moreover,the softening temperature of low temperature ash from the washed sample was as high as 1450◦C,538◦C higher than the low temperature ash from the original sample;the base acid ratio and fouling index were improved from high slagging and fouling risk(1.7 and 90.8)of the original organic solid waste to low and medium risk(0.4 and 3.5),respectively.All these results signified the contributing effect of proposed semi-continuous water washing method on the combustion of agricultural organic solid waste.In a word,this study provided a promising method for fouling and slagging inhibition during the agricultural organic solid waste combustion. | Xiangxi Wang Zhenzhong Hu Jinrong Ma Linlin Yi Jian Li Yanfeng Cheng Jianfei Ma Na An Feng Wang Xian Li Junjun Yan Bo Wei Yue Li Guangqian Luo Hong Yao | 2023 | Carbon Resources Conversion2023，6，1： | 0 |
| 12 | InSb Nanowiers Prepared in Ion-track Template显示文摘 | Yao Huijun Liu Jie Mo Dan Cui Junpeng Duan Jinglai Hou Mingdong Sun Youmei Chen Yanfeng Xu Zhihao | 2006 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2006，，1： | 0 |
| 13 | Hierarchical TiO2 Flower-spheres with Large Surface Area and High Scattering Ability: an Excellent Candidate for High Efficiency Dye Sensitized Solar Cells显示文摘 | MA Jian YAO Shiting CHENG Pengfei DU Sisi SUN Yanfeng LIU Fengmin LU Geyu | 2015 | Chemical Research in Chinese Universities2015，31，5： | 0 |
| 14 | Technology and Market Prospect Analysis of Low Cost Small-lift Launch Vehicles for Small Satellites显示文摘The technological development status of new generation low cost small-lift launch vehicles applied to small satellite launch is investigated in this paper. The development trends are summarized, including low cost and rapid response capability, utilization of mature rocket and missile technology, the development of mobile launch technology adopting air-based platforms and use of innovative technology. Moreover, the external power and internal demand of the small-lift launch vehicle are analyzed and the market prospect is forecasted. Finally, proposals for the development of small-lift launch vehicles are put forward, including exploration of the potential of existing rocket and missile technology, development of multi-platform mobile launch technology and further application of innovative technology and ideas. | YAO Yanfeng CUI Yinghui FAN Wei PEI Shengwei | 2016 | Aerospace China2016，17，3： | 0 |
| 15 | Synergetic process between wind power and sewage sludge pyrolysis in a novel renewable-energy microgrid system显示文摘To relieve the stress of sewage sludge(SS)disposal and effectively increase the use of renewable energy,a novel renewable-energy microgrid system(REMS)was developed,specifically designed to integrate a wind power plant(WPP)with energy storage and the SS pyrolysis process for heat and power generation.Based on a lab-scale pyrolysis experiment and 7-day numerical analysis,we studied the energy-recycling potential of SS and simulated the operational behaviours of REMS.According to the results,the calorific values of the pyrolytic gaseous and liquid products were better than those of the raw material,at 16.19 and 33.53 MJ/kg,respectively.The proposed REMS performed well in power supply and energy utilization with a design performance index of 99.23 when the WPP capacity was 200 MWe and the initial wind-energy curtailment rate was 30%.It indicates that by converting SS into flammable gas,condensable liquid and carbon-rich solid residue,curtailed wind energy could be saved and the synergy between wind power and the SS pyrolysis process enabled the proposed microgrid system to effectively utilize renewable energy and provide reliable on-demand power service.The REMS installed with a 155-MWe WPP achieved the optimal design in system performance,environmental benefit and construction cost under the initial wind-curtailment rate of 34.12%.The design scheme makes REMS capable of satisfying the 15.10-GWh power demand of end users and the 1700-t/day SS disposal need,and the curtailed wind energy could be reduced to zero. | Chang Liu Jiankun Zhuo Yanfeng He Shuiqing Li Qiang Yao | 2023 | Clean Energy2023，7，3： | 0 |
| 16 | The in vivo targeted molecular imaging of fluorescent silicon nanoparticles in Caenorhabditis elegans显示文摘 | Yanfeng Zhou Yun Zhang Yiling Zhong Rong Fu Sicong Wu Qin Wang Houyu Wang Yuanyuan Su Huimin Zhang Yao He | 2018 | Nano Research2018，11，5： | 0 |
| 17 | Recombinant chimpanzee adenovirus vector vaccine expressing the spike protein provides effective and lasting protection against SARS-CoV-2 infection in mice显示文摘SARS-CoV-2 infection is a global public health threat.Vaccines are considered amongst the most important tools to control the SARS-CoV-2 pandemic.As expected,deaths from SARS-CoV-2 infection have dropped dramatically with widespread vaccination.However,there are concerns over the duration of vaccine-induced protection,as well as their effectiveness against emerging variants of concern.Here,we constructed a recombinant chimpanzee adenovirus vectored vaccine expressing the full-length spike of SARS-CoV-2(Ad C68-S).Rapid and high levels of humoral and cellular immune responses were observed after immunization of C57BL/6J mice with one or two doses of Ad C68-S.Notably,neutralizing antibodies were observed up to at least six months after vaccination,without substantial decline.Single or double doses Ad C68-S immunization resulted in lower viral loads in lungs of mice against SARS-CoV-2 challenge both in the short term(21 days)and long-term(6 months).Histopathological examination of Ad C68-S immunized mice lungs showed mild histological abnormalities after SARS-CoV-2 infection.Taken together,this study demonstrates the efficacy and durability of the Ad C68-S vaccine and constitutes a promising candidate for clinical evaluation. | Mingqing Lu Kunpeng Liu Yun Peng Zhe Ding Yingwen Li Alexander Tendu Xue Hu Ge Gao Weiwei Guo Hang Liu Juhong Rao Jiaxuan Zhao Miaoyu Chen Zhiming Yuan Gary Wong Chao Shan Yanfeng Yao Jiaming Lan | 2022 | Virologica Sinica2022，37，4： | 0 |
| 18 | High-speed flexible near-infrared organic photodiode for optical communication显示文摘Optical communication is a particularly compelling technology for tackling the speed and capacity bottlenecks in data communication in modern society.Currently,the silicon photodetector plays a dominant role in high-speed optical communication across the visible-near-infrared spectrum.However,its intrinsic rigid structure,high working bias and low responsivity essentially limit its application in next-generation flexible optoelectronic devices.Herein,we report a narrow-bandgap non-fullerene acceptor(NFA)with a remarkableπ-extension in the direction of both central and end units(CH17)with respect to the Y6 series,which demonstrates a more effective and compact 3D molecular packing,leading to lower trap states and energetic disorders in the photoactive film.Consequently,the optimized solution-processed organic photodetector(OPD)with CH17 exhibits a remarkable response time of 91 ns(λ=880 nm)due to the high charge mobility and low parasitic capacitance,exceeding the values of most commercial Si photodiodes and all NFA-based OPDs operating in self-powered mode.More significantly,the flexible OPD exhibits negligible performance attenuation(<1%)after bending for 500 cycles,and maintains 96% of its initial performance even after 550 h of indoor exposure.Furthermore,the high-speed OPD demonstrates a high data transmission rate of 80 MHz with a bit error rate of 3.5×10^(-4),meaning it has great potential in next-generation high-speed flexible optical communication systems. | Yu Zhu Hongbin Chen Ruiman Han Hao Qin Zhaoyang Yao Hang Liu Yanfeng Ma Xiangjian Wan Guanghui Li Yongsheng Chen | 2024 | National Science Review2024，11，3： | 0 |
| 19 | Behavior of Mn^(2+) in perovskite manganites with nominal composition La_(0.6-x)Nd_xSr_(0.1)MnO_3显示文摘The fact that there are Mn^(2+) at the A sites in the ABO_3 perovskite phase of manganites with the nominal composition La_(0.6-x)Nd_xSr_(0.1)MnO_3 showed by detailed experimental study and theoretical calculations.The magnetic moments of these Mn^(2+) are antiparallel to those of the Mn ions at the B sites.The content of the Mn^(2+) increases as the average ionic radius,,of the ions at A sites decreases,resulting in the experimentally observed phenomenon that the content of the Mn_3O_4 phase in the manganites decreases with decreasing . | Li, Yanfeng Ji, Denghui Liu, Shaopeng Tang, Guide Li, Zhuangzhi Yao, Yuxi Hou, Denglu Zhu, Minggang | 2012 | Rare Metals2012，31，4： | 0 |
| 20 | Cryo-EM structures of a prokaryotic heme transporter CvdDC显示文摘DearEditor,Heme is an essential cofactor required across all kingdoms of life utilized in numerous biological processes,including cellular respiration.CydDC is a prokaryotic ATP-binding cassette(ABC)transporter required for heme assembling in respiratory cytochrome bd oxidase(Georgiou et al.,1987;Poole et al.,1989),a promising target for drug discovery(Borisov et al.,2011).CydDC is thought to play a role in maintaining an optimum periplasmic redox poise that is required for the incorporation of heme cofactors(Yamashita et al.,2014).It also suggested that CydDC is involved in heme processing by mediating glutathione/cysteine translocation(Cook and Poole,2000;Cook et al.,2002),although a role in heme translocation seems unlikely(Yamashita et al.,2014).To date,CydDC has been shown to be important for disulfide bond formation,motility,respiration,and tolerance to nitric oxide and antibiotics(Poole et al.,2019). | Chen Zhu Yanfeng Shi Jing Yu Wenhao Zhao Lingqiao Li Jingxi Liang Xiaolin Yang Bing Zhang Yao Zhao Yan Gao Xiaobo Chen Xiuna Yang Lu Zhang Luke W.Guddat Lei Liu Haitao Yang Zihe Rao Jun Li | 2023 | Protein & Cell2023，14，12： | 0 |
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