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| 1 | Validation of the Rockall scoring system for outcomes from non-variceal upper gastrointestinal bleeding in a Canadian setting显示文摘AIM: To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death. METHODS: We used data extracted from the Registry of Upper Gastrointestinal Bleeding and Endoscopy including information of 1869 patients with non-variceal upper gastrointestinal bleeding treated in Canadian hospitals. Risk scores were calculated and used to classify patients based on outcomes. For each outcome, we used χ2 goodness-of-fit tests to assess the degree of calibration, and built receiver operating characteristic curves and calculated the area under the curve (AUC) to evaluate the discriminative ability of the scoring system. RESULTS: For rebleeding, the χ2 goodness-of-fit test indicated an acceptable fit for the model [χ2 (8) = 12.83, P = 0.12]. For surgical procedures [χ2 (8) = 5.3, P = 0.73] and death [χ2 (8) = 3.78, P = 0.88], the tests showed solid correspondence between observed proportions and predicted probabilities. The AUC was 0.59 (95% CI: 0.55-0.62) for the outcome of rebleeding and 0.60 (95% CI: 0.54-0.67) for surgical procedures, representing apoor discriminative ability of the scoring system. For the outcome of death, the AUC was 0.73 (95% CI: 0.69-0.78), indicating an acceptable discriminative ability. CONCLUSION: The Rockall scoring system provides an acceptable tool to predict death, but performs poorly for endpoints of rebleeding and surgical procedures. | Robert A Enns Yves M Gagnon Alan N Barkun David Armstrong Jamie C Gregor Richard N Fedorak RUGBE Investigators Group | 2006 | World Journal of Gastroenterology2006，12，48： | 14 |
| 2 | Progressive necrosis after hepatectomy and the pathophysiology of liver failure after massive resection显示文摘 | Yves Panis David M McMullan Jean C Emond | 1997 | Surgery1997，，2： | 2 |
| 3 | Structural and functional analysis of E6 oncoprotein:insights in the molecular pathways of human papillomavirus-mediated pathogenesis显示文摘 | Yves N Murielle M Sebastian C | 2006 | Molecular Cell2006，21，5： | 1 |
| 4 | Control of n-alkenes crystallization by ethylene-vinyl acerate copolymers显示文摘 | EMMANUELLE M YVES C FRANCK E et ak | 2005 | Journal of Colloid and Interface Science2005，290，2： | 1 |
| 5 | ADAMTS10 Mutations in Autosomal Recessive Weill-Marchesani Syndrome显示文摘 | Nathalie Dagoneau Catherine Benoist-Lasselin Céline Huber Laurence Faivre André Mégarbané Abdulrahman Alswaid Hélène Dollfus Yves Alembik Arnold Munnich Laurence Legeai-Mallet Valérie Cormier-Daire | 2004 | The American Journal of Human Genetics2004，，5： | 1 |
| 6 | Progressive necrosis after hepatectomy and the pathophysiology of liver failure after massive resection显示文摘 | Yves Panis David M McMullan Jean C Emond | 1997 | Surgery1997，，2： | 1 |
| 7 | Scherffelia dubia centrin exhibits a specific mechanism for Ca2 -controlled target binding 显示文摘 | Laura R Isabelle D Liliane A Yves B Simona M Jos A C Constantin T C | 2010 | Biochemistry2010，49，： | 1 |
| 8 | Structural and functional analysis of E6 oncoprotein:insights in the molecular pathways of human papillomavirus-mediated pathogenesis 显示文摘 | YVES N MURIELLE M SEBASTIAN C | 2006 | Mol Cell2006，21，： | 1 |
| 9 | Design optimization of a self- eleaning moving-bed bioreaetor for seawater denitrilication 显示文摘 | DUPI A M YVES C SERGE P | 2006 | ater Research2006，40，2： | 1 |
| 10 | Effect of Ginkgo biloba (EGb 761) on staurosporine-induced neuronal death and caspase activity in cortical cultured neurons显示文摘 | Lourdes M Julio M Yves C | 2004 | Brain Researgh2004，1002，12： | 1 |
| 11 | Metabolite profiling study of propranolol in rat using LC/MS/MS analysis显示文摘 | Beaudry F Yves Le Blanc J C Coutu M | 1999 | Biomed Chromatogr1999，13，： | 1 |
| 12 | Primary structure of Torpedo califomica acetylcholinesterase deduced from its cDNA sequence显示文摘 | MARK S SHELLEY C YVES M | | Nature0，，： | 1 |
| 13 | Hydrodynamics of~orizontal subsurface flow constructed wetlands显示文摘 | Florent C Gerard M Yves G | 2003 | Ecological Engin- eering2003，21，2： | 1 |
| 14 | Normoglycemic plasma glucose levels affect F-^18FDG uptake in the brain显示文摘 | Jonas C Koen M Yves D | 2010 | Ann Nucl Med2010，24，50： | 1 |
| 15 | Structural and Functional Analysis of E6 Oncoprotein:Insights in the Molecular Pathways of Human Papillomavirus-Mediated Pathogenesis显示文摘 | Yves N Murielle M Sebastian C | 2006 | Molecular Cell2006，21，5： | 1 |
| 16 | Hydrodynamics of horizontal subsurface flow constructed wetlands显示文摘 | FLORENT C GERARD M YVES G | 2003 | Ecological Engineering2003，21，2： | 1 |
| 17 | Drug concentration response relationship in normal volunteers aider oral administration of losartan, an angiotensin II receptor antagonist 显示文摘 | ALAIN M YVES C JURG N | 1992 | Clin Pharmacol Ther1992，51，5： | 1 |
| 18 | Drug concentration response relationship in normal volunteers after oral administration of losartan,an angiotensin Ⅱ receptor antagonist显示文摘 | Alain M Yves C Jurg N | 1992 | Clin Pharmacol Ther1992，51，： | 1 |
| 19 | Hydrodynamics of horizontal subsurface flow constructed wetlands 显示文摘 | Florent C Ge rard M Yves G | 2003 | Ecological Engineering2003，21，： | 1 |
| 20 | Ultra-high-density phase-change storage and memory 显示文摘 | HENDRIK F H MARIN O B YVES C M MICHAEL B KUMAR H W | 2006 | Nature Materials2006，5，5： | 1 |
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