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| 1 | 24 h continuous observation of sodium layer over Wuhan by lidar显示文摘Based on the dual-wavelength lidar we have developed, the 24 h continuous ob- servation has been realized in its sodium channel by using Faraday atomic filter technology and other relevant technologies. This will facilitate the continuous ob- servation of the sodium layer and the relevant upper atmosphere over Wuhan. A result of about 50 h observation indicates that the daytime column density of so- dium layer over Wuhan is slightly increased compared to that during the nighttime, and the characteristics of the sporadic sodium layer occurring during the daytime are compared with that during the nighttime. | CHENG XueWu GONG ShunSheng LI FaQuan DAI Yang SONG Juan WANG JiaMin LI FengYan | 2007 | Science China(Physics,Mechanics & Astronomy)2007，50，3： | 8 |
| 2 | Autonomous navigation method and technology implementation of high-precision solar spectral velocity measurement显示文摘The velocity information of spacecraft can be directly obtained by the autonomous navigation method based on astronomical spectral velocity measurement. It provides complete direct velocity measurement information for the traditional navigation methods represented by astronomical angle measurement and astronomical ranging, which is of great significance for spacecraft high precision autonomous navigation. This paper comprehensively introduces the principle and navigation method of astronomical spectral velocity measurement, as well as the technical realization of the solar atomic frequency discriminator for autonomous navigation(SAFDAN) based on atomic frequency discrimination velocity measurement. The new SAFDAN is the first instrument to measure the Doppler velocity of spacecraft relative to the Sun. Carried by the CHASE mission, the in-orbit experiment of the SAFDAN is realized, and the in-orbit velocity measurement accuracy reaches 1.93 m/s, which effectively verifies the feasibility of the astronomical spectral velocity measurement method and technology. | Wei Zhang Yong Yang Wei You JinZhou Zheng Hui Ye KaiJun Ji Xiao Chen Xin Lin QingLong Huang XueWu Cheng Wei Zhang FaQuan Li | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 3 |
| 3 | Lidar observation campaigns on diurnal variations of the sodium layer in Beijing and Wuhan, China显示文摘Based on observations from daytime lidars in eastern China,diurnal cycles of the sodium layer over Wuhan(30.5°N,114.6°E)and Beijing(40.5°N,116°E)are investigated.Diurnal variations of Na density,root mean square(RMS)layer width,and centroid height of the sodium layer are analyzed.Results reveal that the large diurnal cycles of the sodium layer are controlled mainly by 24-hr oscillations at the two observation sites.The diurnal variation of the sodium layer over Wuhan was modulated mainly by tidal perturbations during the lidar observation campaign.Conversely,the diurnal variation over Beijing was controlled principally by photoionization and photochemistry effects during another campaign,and there was little evidence of direct tidal perturbations.These comparisons suggest that the diurnal variation of the sodium layer perhaps has obvious regional characteristics across China.The variation can be either controlled mainly by tidal perturbations or by photoionization and photochemistry effects in different seasons. | GONG ShaoHua YANG GuoTao CHENG XueWu GONG Shun Sheng XU JiYao LI FaQuan GONG Wei WANG JiHong | 2015 | Science China Earth Sciences2015，58，8： | 2 |
| 4 | Joint observation results of Na layer and ionosphere in Wuhan during the Total Solar Eclipse显示文摘During the total solar eclipse on July 22, 2009 in Wuhan, the joint observation test of Na layer and ionosphere was conducted by using the daytime observation atmospheric lidar and the GPS ionosphere detector. The results show that the full width at half maximum(FWHM) of Na layer density slightly narrowed during the total solar eclipse and broadened after the eclipse, while the height of Na peak slightly decreased in the eclipse and increased after the eclipse. These implying that Na layer changes reflect the rapid process of sunrise and sunset. The ionosphere total electron content(TEC) and the sky background light noise also presented an obvious fluctuation characteristic with the changes of solar irradiation during the process of total solar eclipse. The difference lies in that the changes of FWHM of Na layer atoms are much slower than that of ionosphere, the reason for this might be that the Na layer, after being disturbed by the total solar eclipse, will generate a series of complicated photochemical reactions and momentum transport processes, and then recombine the Na atoms. The Na atoms to be detected by the lidar need a lag process, which rightly conforms to the theoretical simulated results. | CHENG XueWu YANG Yong WANG ZeLong LI FaQuan YANG GuoTao ZHAO ZhengYu GONG Wei WANG JiHong HU Xiong LIN Xin WU XiaoCheng SONG ShaLei GONG ShunSheng | 2016 | Science China Earth Sciences2016，59，2： | 1 |
| 5 | Effects of reactive oxygen species on cellular wall disassembly of banana fruit during ripening显示文摘 | Guiping Cheng Xuewu Duan John Shi Wangjin Lu Yunbo Luo Weibo Jiang Yueming Jiang | 2008 | Food Chemistry2008，，2： | 1 |
| 6 | Activity-trip chaining behavior of urban low-income populations in Nanjing, China: A structural equations analysis显示文摘 | Zhaoming Chu Hui Chen Lin Cheng Xuewu Chen Senlai Zhu | 2014 | Discrete Dynamics in Nature and Society2014，，： | 1 |
| 7 | Joint observations of sporadic sodium and sporadic E layers at middle and low latitudes in China显示文摘Sporadic sodium layers(SSLs)were studied with sodium(Na)lidar at Beijing(40.5°N,116.0°E)and Haikou(19.5°N,109.1°E)in China.The altitude distribution,strength factors,and occurrence time of SSL and sporadic E(Es)layer events were statistically analyzed at both observing sites.SSL occurrence had a maximum near22:00 local time,and Eslayer occurrence had a maximum before midnight.The altitude distributions of SSL and Es layer events were better correlated at Haikou than at Beijing.All the average values of height and strength factor for SSL and Eslayer events,as well as the average of the maximum frequency that can be reflected by the Eslayer(foEs),at Beijing were higher than those at Haikou.A better correlation between SSL and Eslayer events was also found at Haikou,and the formation of SSLs was considered to likely depend on the seasonal variability of chemical and dynamical processes. | Jing Jiao Guotao Yang Xu Zou Shaohua Gong Jihong Wang Dawei Tian Wenzhen Zhang Tiemin Zhang Xianchang Yang Jun Fu Xuewu Cheng | 2014 | Chinese Science Bulletin2014，59，29： | 1 |
| 8 | Numerical simulation of Shack Hartmaan wavefront sensor to characterize the turbulence phase statistics显示文摘 | Zhiling Jiang Yang Dai Faquan Li Xuewu Cheng | 2006 | Optics and Lasers in Engineering2006，44，： | 1 |
| 9 | Analysis on Shack-Hartmann wave-front sensor with Fourier optics显示文摘 | Dai Yang Li Faquan Cheng Xuewu | 2007 | Opticsand Laser Tect- nology2007，39，7： | 1 |
| 10 | An RNA-RNA crosstalk network involving HMGB1 and RICTOR facilitates hepatocellular carcinoma tumorigenesis by promoting glutamine metabolism and impedes immunotherapy by PD-L1+ exosomes activity显示文摘Hepatocellular carcinoma(HCC)is the global leading cause of cancer-related deaths due to the deficiency of targets for precision therapy.A new modality of epigenetic regulation has emerged involving RNA-RNA crosstalk networks where two or more competing endogenous RNAs(ceRNAs)bind to the same microRNAs.However,the contribution of such mechanisms in HCC has not been well studied.Herein,potential HMGB1-driven RNA-RNA crosstalk networks were evaluated at different HCC stages,identifying the mT0RC2 component RICTOR as a potential HMGB1 ceRNA in HBV^(+)early stage HCC.Indeed,elevated HMGB1 mRNA was found to promote the expressio n of RICTOR mRNA through competitively bin ding with the miR-200 family,especially miR-429.Functio nal assays emplo ying overexpressi on or in terference strategies dem on strated that the HMGB1 and RICTOR 3zuntra nslated regions(UTR)epigenetically promoted the malignant proliferation,self-renewal,and tumorigenesis in HCC cells.Intriguingly,in terference agai nst HMGB1 and RICTOR in HCC cells promoted a stron ger an ti-PD-L1 immuno therapy resp on se,which appeared to associate with the production of PD-L1^(+)exosomes.Mechanistically,the HMGB1-driven RNA-RNA crosstalk network facilitated HCC cell glutamine metabolism via dual mechanisms,activating a positive feedback loop involving mT0RC2-AKT-C-MYC to upregulate glutamine synthetase(GS)expression,and inducing mTORCI signaling to derepress SIRT4 on glutamate dehydrogenase(GDH).Meanwhile,this crosstalk network could impede the efficacy of immunotherapy through mTORCI-P70S6K dependent PD-L1 production and PD-L1^(+)exosomes activity.In conclusion,our study highlights the non-coding regulatory role of HMGB1 with implicatio ns for RNA-based therapeutic targeting together with a predictio n of an ti-PD-L1 immuno therapy in HCC. | Yanping Wei Xuewu Tang Yibin Ren Yun Yang Fengliang Song Jingbo Fu Shuowu Liu Miao Yu Jing Chen Suyang Wang Kecheng Zhang Yexiong Tan Zhipeng Han Lixjn Wei Baohua Zhang Zhangjun Cheng Liang Li Hongyang Wang | 2022 | Signal Transduction and Targeted Therapy2022，7，1： | 0 |
| 11 | Property variation of ionic liquid [Bmim][AuCl_4] immobilized on carboxylated polystyrene submicrospheres with a small surface area显示文摘In order to understand the effect of surface chemical groups on the immobilized species, Au-containing imidazolium-based ionic liquid (IL) [Bmim][AuCl4] was intentionally immobilized on polystyrene (PS) submicrospheres (d~300 nm) with a very small surface area (4-10 m2/g), which possess carboxyl-moiety (COONa or COOH) on the surface. The behavior of immobilized [Bmim][AuCl4 ] on the two types of submicrospheres was investigated by transmission electron microscopy (TEM), differential scanning calorimetry (DSC), and powder X-ray diffraction (XRD). It was revealed that the melting points (Tm) of [Bmim][AuCl4 ] that had been immobilized on PS-COONa and PS-COOH submicrospheres were decreased by 2.7 and 4.1℃, respectively. The interaction mechanism between the IL and submicrosphere surface moieties was further analyzed by X-ray absorption fine structure (XAFS) analysis. The data indicated that the coordination environment of Au species changed markedly when [Bmim] [AuCl4] was immobilized on the surfaces of PS-COONa and PS-COOH submicrospheres, as illustrated by the decrease in white line peak intensity. The effect of surface COOH groups on Tm depression and the white line peak intensity of the XANES spectrum is more pronounced than that of COONa groups, most likely due to the possible hydrogen bond formation between the COOH group and [Bmim]+. | HE YaXing FU HaiYing LI Cheng JI Xiang GE XueWu ZOU Yang JIANG Zheng XU HongJie WU GuoZhong | 2013 | Chinese Science Bulletin2013，58，24： | 0 |
| 12 | Identification of serous ovarian tumors based on polarization imaging and correlation analysis with clinicopathological features显示文摘Ovarian cancer is one of the most aggressive and heterogeneous female tumors in the world,and serous ovarian cancer(SOC)is of particular concern for being the leading cause of ovarian cancer death.Due to its clinical and biological complexities,ovarian cancer is still considered one of the most di±cult tumors to diagnose and manage.In this study,three datasets were assembled,including 30 cases of serous cystadenoma(SCA),30 cases of serous borderline tumor(SBT),and 45 cases of serous adenocarcinoma(SAC).Mueller matrix microscopy is used to obtain the polarimetry basis parameters(PBPs)of each case,combined with a machine learning(ML)model to derive the polarimetry feature parameters(PFPs)for distinguishing serous ovarian tumor(SOT).The correlation between the mean values of PBPs and the clinicopathological features of serous ovarian cancer was analyzed.The accuracies of PFPs obtained from three types of SOT for identifying dichotomous groups(SCA versus SAC,SCA versus SBT,and SBT versus SAC)were 0.91,0.92,and 0.8,respectively.The accuracy of PFP for identifying triadic groups(SCA versus SBT versus SAC)was 0.75.Correlation analysis between PBPs and the clinicopathological features of SOC was performed.There were correlations between some PBPs(δ,β,q_(L),E_(2),rqcross,P_(2),P_(3),P_(4),and P_(5))and clinicopathological features,including the International Federation of Gynecology and Obstetrics(FIGO)stage,pathological grading,preoperative ascites,malignant ascites,and peritoneal implantation.The research showed that PFPs extracted from polarization images have potential applications in quantitatively differentiating the SOTs.These polarimetry basis parameters related to the clinicopathological features of SOC can be used as prognostic factors. | Yulu Huang Anli Hou Jing Wang Yue Yao Wenbin Miao Xuewu Tian Jiawen Yu Cheng Li Hui Ma Yujuan Fan | 2023 | Journal of Innovative Optical Health Sciences2023，16，5： | 0 |
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