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| 1 | A metabonomic investigation on the biochemical perturbation in liver failure patients caused by hepatitis b virus显示文摘 | Yu, K Sheng, GP Sheng, JF Chen, YM Xu, W Liu, XL Cao, HC Qu, HB Cheng, YY Li, LJ | 2007 | 中国生物学文摘2007，21，11： | 25 |
| 2 | Effects of salvianolic acid-A on NIH/3T3 fibroblast proliferation,collagen synthesis and gene expression显示文摘AIM To investigate the mechanisms ofsalvianolic acid A(SA-A)against liver fibrosisin vitro.METHODS NIH/3T3 fibroblasts were culturedroutinely,and incubated with 10-4mol/L-10-7mol/L SA-A for 22 h.The cell viability wasassayed by[3H]proline incorporation,cellproliferation by[3H]TdR incorporation,cellcollagen synthetic rate was measured with[3H]proline impulse and collagenase digestionmethod.The total RNA was prepared from thecontrol cells and the drug treated cellsrespectively,and α(1)I pro-collagen mRNAexpression was semi-quantitatively analyzedwith RT-PCR.RESULTS 10-4mol/L SA-A decreased cellviability and exerted some cytotoxiciy,while10-5mol/L-10-7mol/L SA-A did not affect cellviability,but inhibited cell proliferationsignificantly,and 10-6mol/L SA-A had the besteffect on cell viability among theseconcentrations of drugs.10-5mol/L-10-6mol/LSA-A inhibited intracellular collagen syntheticrate,but no significant influence on extracellularcollagen secretion.Both 10-5mol/L and10-6mol/L SA-A could decrease α(1)I pro-collagen mRNA expression remarkably.CONCLUSION SA-A had potent action againstliver fibrosis.It inhibited NIH/3T3 fibroblastproliferation,intracellular collagen syntheticrate and type I pro-collagen gene expression,which may be one of the main mechanisms of thedrug. | Liu CH Hu YY Wang XL Liu P Xu LM | 2000 | World Journal of Gastroenterology2000，6，3： | 25 |
| 3 | Antifungal activities and action mechanisms of compounds from Tribulus terrestris L.显示文摘 | Zhang JD Xu Z Cao YB Chen HS Yan L An MM Gao PH Wang Y Jia XM Jiang YY | 2006 | 第二军医大学学报2006，27，5： | 14 |
| 4 | cDNA microarray analysis of differential gene expression in Candida albicans biofilm exposed to farnesolides显示文摘 | Cao YY Cao YB Xu Z Ying K IA Y Xie Y Zhu ZY Chen WS Jiang YY | 2006 | 第二军医大学学报2006，27，4： | 3 |
| 5 | Schwannoma of the gastrointestinal tract : a clinicopathological, immunohistochmnical and ultrastructural study of 33 cases 显示文摘 | Hou YY Tan YS Xu JF | 2006 | Histopathology2006，48，9： | 1 |
| 6 | Optimization of theaflavin biosyn- thesis from tea polyphenols using immobilized enzyme system and response surface methology显示文摘 | Tu YY Xu XQ Xia HL | 2005 | Biotechnol Lett2005，27，： | 1 |
| 7 | Impaired function of CDI9(+) CD24(hi) CD38(hi) regulatory B cells in patients with pemphigus显示文摘 | Zhu HOa Xu RC Chen YY | 2015 | BrJ Dermatol2015，172，1： | 1 |
| 8 | Application of Clark comfortable nursing mode in enhancing self-management ability of patients with chronic kidney disease显示文摘 | Wang S Xu HL Cui YY | 2014 | Chin Nurs Research2014，28，14： | 1 |
| 9 | Relationship between endogenous concentrations and serum cholesteryl ester transfer protein concentrations in Chinese women显示文摘 | Zhang CN Zhuang YY Qiang HJ Liu XC Xu RJ Wu YZ | 2001 | Clin Chim Acta2001，314，： | 1 |
| 10 | Macroscopic serosal classifica- tion predicts peritoneal recurrence for patients with gastric cancer underwent potentially curative surgery 显示文摘 | Sun Z Xu YY Wang ZN | 2011 | Ann Surg Oncol2011，18，4： | 1 |
| 11 | Novel mutations in DAX1 of X-linked adrenal hypoplasia congenita over several generations in one family 显示文摘 | Xu XQ Feng YY Yuan WX | 2013 | Endocr Pract2013，19，4： | 1 |
| 12 | Determination of polybrominated diphenyl ethers in human semen 显示文摘 | Liu PY Zhao YX Zhu YY Qin ZF Ruan XL Zhang YC Chen B J Li Y Yan SS Qin XF Fu S Xu XB | 2012 | Environ Int2012，，42： | 1 |
| 13 | Reserpine impairs spatial working memory performance in monkeys: Reversal by the alpha - 2 adrenergic agonist clonidine显示文摘 | Cai JX Ma YY Xu L | 1993 | Brain Res1993，614，12： | 1 |
| 14 | Intravenous remifentanil and propofol for gastroscopy显示文摘 | Xu ZY Wang X Si YY | 2008 | J Clin Anesth2008，20，5： | 1 |
| 15 | Weekly dynamics ofphytoplankton Functional groups under high water level fluctuations in a subtropicalreservoir bay 显示文摘 | WANG T CAI Q H XU YY | 2011 | Aquatic Ecology2011，45，2： | 1 |
| 16 | Prevalence of dry eye among adult Chinese in the Beijing Eye Study显示文摘 | Jie Y L Xu YY Wu | 2009 | Eye CLond)2009，23，3： | 1 |
| 17 | Quality of life in women with female pattern hair loss and the impact of topical minoxidil treatment on quality of life in these patients显示文摘 | Zhuang XS Zheng YY Xu JJ | 2013 | Exp Ther Med2013，6，2： | 1 |
| 18 | Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory 显示文摘 | Zhang YY Xu ZP Wang H | 2012 | Ann Neurol2012，71，68： | 1 |
| 19 | Variations in arsenic methylation capacity and oxidative DNA lesions over a 2-year period in a high arsenicexposed population显示文摘 | Xu YY Wang Y Li X | 2008 | Int Arch Occup Environ Health2008，10，： | 1 |
| 20 | Induction of apoptosis in SGC -7901 cellsby polysaccharide-peptide GFPSlb from the cultured mycelia of Grifolafrondosa GF9801 显示文摘 | Cui FJ Li Y Xu YY | 2007 | Toxicology In Vitro2007，，41： | 1 |
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