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101篇 您的检索式:作者名="Wroblewska"
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1Type 3 innate lymphoid cell-derived lymphotoxin prevents microbiota-dependent inflammation显示文摘Splenomegaly is a well-known phenomenon typically associated with inflammation.However,the underlying cause of this phenotype has not been well characterized.Furthermore,the splenomegaly phenotype seen in lymphotoxin(LT)signaling-deficient mice is characterized by increased numbers of splenocytes and splenic neutrophils.Splenomegaly,as well as the related phenotype of increased lymphocyte counts in non-lymphoid tissues,is thought to result from the absence of secondary lymphoid tissues in LT-deficient mice.We now present evidence that mice deficient in LTα1β2 or LTβR develop splenomegaly and increased numbers of lymphocytes in non-lymphoid tissues in a microbiota-dependent manner.Antibiotic administration to LTα1β2-or LTβR-deficient mice reduces splenomegaly.Furthermore,re-derived germ-free Ltbr−/−mice do not exhibit splenomegaly or increased inflammation in non-lymphoid tissues compared to specific pathogen-free Ltbr−/−mice.By using various LTβ-and LTβR-conditional knockout mice,we demonstrate that retinoic acid-related orphan receptorγT-positive type 3 innate lymphoid cells provide the required active LT signaling to prevent the development of splenomegaly.Thus,this study demonstrates the importance of LT-mediated immune responses for the prevention of splenomegaly and systemic inflammation induced by microbiota.Yuan Zhang Tae-Jin Kim Joanna A Wroblewska Vera Tesic Vaibhav Upadhyay Ralph R Weichselbaum Alexei V Tumanov Hong Tang Xiaohuan Guo Haidong Tang Yang-Xin Fu 2018Cellular & Molecular Immunology2018,15,7:3
2Dra/ AfaE Adhesin of uropathogenic Dr/Afa_ Escherichia coli me diales mortality in pregnant rats显示文摘Wroblewska Seniuk K Selvarangan R Hart A 2005Infect Immun2005,73,11:1
3Goblet cells density of bulbar conjunctiva after the iridectomy显示文摘Wroblewska E 1999Klin-Oczns1999,101,:1
4The Reduction of Cow Milk ProteirLs Immunoreactivity by Two-Step Enzymatic Hydrolysis显示文摘WROBLEWSKA B JEDRYCHOWSKI L SZABO E 2005Acta Alimentaria2005,34,3:1
5The Allergenicity of a Low Molecular Fraction of Cow Milk Protein Hydrolysates显示文摘WROBLEWSKA B JEDRYCHOWSKI L FARJAN M 2007Milchwissenschaft2007,62,4:1
6Immunoreactive properties of peptide fractions of cow whey milk proteins after enzymatic hydrolysis显示文摘Wroblewska B Karamac M Amarowicz R 0,,:1
7Anomalies of the coronary arteries in children显示文摘Werner B Wroblewska KM Pleskot M 2001Med Sci Monit2001,7,:1
8Ira-munoreaetive properties of peptide fractions of cow whey milk pro- teins after enzymatic hydrolysis显示文摘WROBLEWSKA B KARAMAC M AMAROWICZ R 2004Int J Food Sci Tech2004,39,8:1
9Epoxidation of allyl alcohol to glycidol over the microporous TS-1 catalyst显示文摘WROBLEWSKA A FAJDEK A 2010Journal of Hazardous Materials2010,179,123:1
10The response of rats to feeding with diets containing grapefruit flavonoid extract显示文摘JUSKIEWICZ J ZDUNCZYK Z WROBLEWSKA M 2002Food Res In2002,35,:1
11Reduction of the antigenicity of whey proteins by lactic acid fermentation 显示文摘LUCJAN J WROBLEWSKA B 1999Food and Agricultural Immunology1999,11,:1
12Allozyme differentiation and genetic structure of Lady's slipper island populations ( Cypripedium calceolus) in north-east Poland 显示文摘Brzosko E Ratkiewicz M Wroblewska A 2002a 2002Bot J Linn Soc2002,138,:1
13Spatial genetic structure and donal diversity of island populations of Lady's slipper ( Cypripedium calceolus ) from the Biebrza National Park ( northeast Poland) 显示文摘Brzosko E Wroblewska A Ratkiewicz M 2002b 2002Mol Ecol2002,11,:1
14Low allozymic variation in two island populations of Listera ovata (Orchidaceae) from NE Poland 显示文摘Brzosko E Wroblewska A 2003a 2003Ann Bot Fennici2003,40,:1
15Effect of non-digestible oligosaceharides on gut microeeosystem in rats显示文摘Bielecka M Biedrzycka E Majkowska A J uskiewicz J Wroblewska M 2002Food Res Inter2002,35,:1
16Genetic variation and clonal diversity in island Cephalanthera rubra populations from the Biebrza National Park, Poland 显示文摘Brzosko E Wroblewska A 2003b 2003Bot J Linn Soc2003,143,:1
17Antinociceptive effects of N-acetylaspartylglutamate ( NAAG ) peptidase inhibitors ZJ- 11, ZJ-17 and ZJ43 in the rat formalin test and in the rat neuropathic pain model 显示文摘Yamamoto T Hirasawa S Wroblewska B 2004Eur J Neurosci2004,20,2:1
18Reduction of the antigenicityofwhey proteins by lactic acid fermentation显示文摘Jedrychowski L Wroblewska B 1999Food and Agricul-tural Immunology1999,11,:1
19Molecular mimicry in virus infection:crossreaction of measles virus phosphoprotein or of herpes simplex virus protein with human intermediate filaments显示文摘Fujinami RS Oldstone MB Wroblewska Z 1983Proc Natl Acad Sci USA1983,80,8:1
20Lipid disturbances in a two-year follow-up after successful kidney transplantation 显示文摘Kisielnicka E Zdrojewski Z Wroblewska M 2000Transplant Proc2000,32,:1
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